Clinical trials: completed, sponsored by Emory University
Cancer
Resistance Training to Improve Fatigue and Physical Function in Postmenopausal Breast Cancer Survivors
This study will begin to fill a knowledge gap by determine whether changes in kynurenine metabolism occur following Resistance Training (RT) and relate to reductions in inflammation and improved behavioral and physical function…
- Trial name
- NCT03539835
- Testing
- Resistance training (RT), Cognitively-based compassion training control (CBCT)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Emory University
Physical Activity
A Rigorous Evaluation of the Relationship Between Physical Activity and Education Outcomes
The study is a prospective study to examine the impact of a school-based physical activity intervention on fourth and fifth grade elementary students' academic achievement, as measured by standardized test scores.
- Trial name
- NCT03765047
- Testing
- Intervention Arm
- Where
- United States
- Volunteers
- 4,968 people
- Sponsor
- Emory University
Diabetes Mellitus, Type 2, Cystic Fibrosis
Redox Imbalance and the Development of Cystic Fibrosis Diabetes
Cystic fibrosis-related diabetes (CFRD) occurs in almost 20% of teens and 50% of adults. The investigators' long term goal is to determine the cause of CFRD in order to translate this knowledge into therapies aimed at preventing…
- Trial name
- Redoxy (NCT02202876)
- Testing
- Oral Glucose Tolerance Test, High Glycemic Index Meal, Low Glycemic Index Meal
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Emory University
Ewing's Sarcoma, Osteosarcoma
Aflac ST0901 CHOANOME - Sirolimus in Solid Tumors
The best treatment for recurrent cancers or those that do not respond to therapies is not known. Typically, patients with these cancers receive a combination of cancer drugs (chemotherapy), surgery, or radiation therapy.
- Conditions
- Ewing's Sarcoma, Osteosarcoma, Astrocytoma, Atypical Teratoid/Rhabdoid Tumor
- Trial name
- Aflac ST0901 (NCT01331135)
- Testing
- sirolimus
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Emory University
Health Behavior
CBCT for Spiritual Health Clinicians
The Emory University Spiritual Health department will incorporate Cognitively-Based Compassion Training (CBCT) into their training curriculum beginning in Fall 2017, which provides the opportunity to compare students receiving…
- Trial name
- NCT03529812
- Testing
- CBCT-informed training
- Where
- 7 sites in United States
- Volunteers
- 304 people
- Sponsor
- Emory University
Headache, Cervicogenic Headache
Dry Needling for Cervicogenic Headache
This is a single-blinded randomized clinical trial. The primary aim of this study is to compare the effectiveness of dry needling of myofascial trigger points in the muscles of the head and cervical spine in addition to an upper…
- Trial name
- NCT04305223
- Testing
- Dry Needling, Upper extremity stretching program
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Emory University
Chronic Kidney Disease
Two Vitamin D Dosing Strategies in Children With Chronic Kidney Disease
Vitamin D deficiency is common in the general population and more common in children with chronic kidney disease. Vitamin D is very important for bone health, especially in children with chronic kidney disease.
- Trial name
- NCT01909115
- Testing
- 1000 IU of Vitamin D3, 4000 IU of Vitamin D3
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Emory University
Hemophilia, Menstrual Flow Excessive
Extended Half Life Factor (EHF) Products For Heavy Menstrual Bleeding in Hemophilia Carriers
The purpose of this feasibility study is to find out if two clotting factor products, Eloctate [hemophilia A] and Alprolix [hemophilia B], can reduce the amount of menstrual bleeding in female hemophilia A and B carriers (14…
- Trial name
- NCT03272568
- Testing
- Recombinant FVIII Fc fusion product Eloctate, Recombinant FIX Fc fusion product Alprolix, Patient-operated diagnostic device for anemia AnemoCheck.
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Emory University
Health Behavior
Compassion-Centered Spiritual Health for Faculty and Staff
Compassion-Centered Spiritual Health (CCSH) at Emory University was launched as a joint creation by Spiritual Health and the Center for Contemplative Science and Compassion-Based Ethics in 2018.
- Trial name
- NCT04060901
- Testing
- CCSH Intervention for Teams
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Emory University
Chronic Kidney Disease
Stress and CKD Among African Americans
The goal of this study is to determine whether experiencing stress from discrimination may increase chronic kidney disease (CKD) progression in African Americans.
- Trial name
- NCT03387319
- Testing
- Racialized Stressful Event Recall, Non-Racialized Stressful Event Recall
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Emory University
Type 2 Diabetes
Glargine U300 Hospital Trial
The purpose of this study is to find out if treatment with Glargine U300 when compared to Glargine U100 will result in similar sugar control in patients with Type 2 Diabetes (T2D), who are admitted to the hospital and then…
- Trial name
- NCT03013985
- Testing
- Glargine U300, Glargine U100, Glulisine Insulin
- Where
- 4 sites in United States
- Volunteers
- 247 people
- Sponsor
- Emory University
Alzheimer Disease
CBT for African Americans With Cognitive Impairment
The aim of the study is to test the feasibility and acceptability of a six-month cognitive-behavioral therapy (CBT) program (group based and phone-based) compared with usual care, and to determine if the intervention can improve…
- Trial name
- NCT03384069
- Testing
- Group-based Cognitive Behavioral Therapy (CBT), Phone-based Cognitive Behavioral Therapy (CBT)
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Emory University
Vocal Fold Palsy, Dysphagia
Universal Screening for Vocal Fold Motion Impairment in Children Undergoing Congenital Cardiac Surgery
The purpose of this study is to determine how often heart or chest surgery in children leads to problems with the movement of the vocal folds.
- Conditions
- Vocal Fold Palsy, Dysphagia, Congenital Heart Disease in Children
- Trial name
- NCT03882450
- Testing
- Flexible fiberoptic laryngoscopy, Laryngeal ultrasonography
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Emory University
Chronic Pain
Meditation for Pain
The general scope of the study involves meditation and its effects on pain management, narcotic use, and emotional well-being. Half of the participants will receive access to a meditation app, which they will be asked to use for…
- Trial name
- NCT03495726
- Testing
- Headspace app
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- Emory University
Social Behavior, Depression
Contemplative Well-being Apps for the Workplace
The study will examine the use and impact of a meditation app delivered to adult workforce populations facing extreme time demands.
- Conditions
- Social Behavior, Depression, Inflammation
- Trial name
- NCT03452670
- Testing
- Active Group, Waitlist Group
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Emory University
Retinoblastoma, Clear Cell Sarcoma
Simvastatin With Topotecan and Cyclophosphamide in Relapsed and/or Refractory Pediatric Solid and CNS Tumors
This is a Phase I trial with new experimental drugs such as simvastatin in combination with topotecan and cyclophosphamide in the hopes of finding a drug that may work against tumors that have come back or that have not responded…
- Conditions
- Retinoblastoma, Clear Cell Sarcoma, Renal Cell Carcinoma, Rhabdoid Tumor
- Trial name
- AflacST1402 (NCT02390843)
- Testing
- Simvastatin, Cyclophosphamide, Topotecan
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Emory University
Cardiovascular Diseases
The Morehouse-Emory Cardiovascular Center for Health Equity Study: Clinical Intervention Project
This study will recruit from participants in the Morehouse-Emory Cardiovascular (MECA) study for a clinical intervention examining cardiac outcomes between participants who are randomized to received Health360x (a web-based and…
- Trial name
- MECA (NCT03308812)
- Testing
- Health360x, Health Coach
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- Emory University
Mental Disorder
Engaging Patients With Mental Disorders From the ED in Outpatient Care
This study will compare the effectiveness of professional and peer care managers in improving linkage to and engagement in outpatient care after an emergency department (ED) discharge, as well as the mechanisms by which…
- Trial name
- EPIC (NCT02989805)
- Testing
- Care Management
- Where
- United States
- Volunteers
- 326 people
- Sponsor
- Emory University
Influenza A Subtype H5N1 Infection
Durability and Impact of the Seasonal Influenza Vaccine on H5 Induced B Cell Response
The study is a prospective single site exploratory study to examine the impact of Food and Drug Administration (FDA) approved seasonal flu vaccine on the immune responses of H5N1 vaccine previously received with or without the…
- Trial name
- HIPCVAX-010S (NCT03701061)
- Testing
- Seasonal Influenza Vaccine
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Emory University
Coronary Artery Disease
Age and Endothelial Progenitor Cell Mobilization
It is hypothesized that aging is associated with reduced vascular injury-induced endothelial progenitor cell activity, resulting in impaired vascular repair and increased vascular disease.
- Trial name
- AGE-PCI (NCT00585949)
- Testing
- Percutaneous Coronary Angioplasty, Angiography
- Where
- 2 sites in United States
- Volunteers
- 123 people
- Sponsor
- Emory University