Clinical trials: completed, sponsored by Emory University
Kidney Transplantation, Liver Transplantation
Quality of Life in Pediatric Transplant Recipients
Adherence to medical regimens refers to what degree a patient chooses to follow the advice given by his/her healthcare provider.
- Conditions
- Kidney Transplantation, Liver Transplantation, Heart Transplantation, Lung Transplantation
- Trial name
- NCT00209196
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Emory University
Heart Failure, Systolic, Left Bundle Branch Block
Optimal Coronary Sinus Lead Implantation Using Intracardiac Impedography and Magnetic Resonance Imaging
Despite the dramatic effect of cardiac resynchronization therapy (CRT) on survival and morbidity in people with congestive heart failure, 50-70% of eligible patients do not respond to this intervention.
- Trial name
- NCT01129635
- Testing
- Cardiac Resynchronization Therapy (CRT) implantation
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Emory University
Cystic Fibrosis, Immune Function
Glutamine Supplementation in Cystic Fibrosis
Patients with cystic fibrosis develop frequent and potentially life-threatening lung infections. Recent studies suggest that the nutrient "glutamine" may help the body fight off infection.
- Trial name
- CFG (NCT01051999)
- Testing
- Glutamine, L-alanine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Emory University
Diseases, Metabolic, Insulin Sensitivity
Comparing Soybean Oil-Based (Intralipid) With an Olive Oil-Based (ClinOleic) Lipid Emulsion on Healthy Volunteers
Many patients in the hospital who are malnourished or not eating received intravenous feeding or total parenteral nutrition (TPN). Despite improving nutrition, TPN may increase the risk of infections and hospital complications.
- Trial name
- TPN1 (NCT02185729)
- Testing
- Intralipid, ClinOleic, Dextrose
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Emory University
Diabetes
Intensive Insulin Therapy in Patients Undergoing Coronary Artery Bypass Surgery
High blood glucose levels (hyperglycemia) in cardiac surgery patients with diabetes are associated with increased risk of hospital complications.
- Trial name
- CABG (NCT01361594)
- Testing
- Regular insulin (intensive treatment), Regular Insulin (conventional treatment)
- Where
- United States
- Volunteers
- 338 people
- Sponsor
- Emory University
Type 2 Diabetes, Hypertension
Free Fatty Acid-Induced Hypertension in Obese Subjects With Type 2 Diabetes
Insulin resistance has been implicated as the central pathogenetic feature of cardiovascular risk factor cluster that includes hypertension, impaired glucose tolerance, diabetes, dyslipidemia, and hemostatic disorders.
- Trial name
- NCT00738023
- Testing
- Rosiglitazone, Normal saline 0.9%, Intralipid 20%
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Emory University
Peripheral Arterial Disease
Granulocyte-Macrophage Stimulating Factor in the Treatment of Peripheral Arterial Disease
Peripheral arterial disease is a common condition in older adults involving poor arterial circulation in the legs leading to leg pain and debility.
- Trial name
- GPAD-2 (NCT01041417)
- Testing
- Granulocyte-Macrophage Stimulating Factor (GM-CSF)
- Where
- United States
- Volunteers
- 159 people
- Sponsor
- Emory University
PSORIASIS
Etanercept and Vascular Function in Psoriasis
The investigators plan to measure the health of the vascular system of subjects taking Etanercept for the treatment of plaque psoriasis.
- Trial name
- EVIP (NCT01989689)
- Testing
- Etanercept
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Emory University
Hypertension
Effect of Nebivolol on Oxidative Stress and Endothelial Progenitor Cells
Hypertension, or high blood pressure, is a common disease that affects many Americans, and can lead to devastating consequences such as heart attack, stroke, and death if not treated.
- Trial name
- NCT01041287
- Testing
- Nebivolol, Metoprolol succinate
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Emory University
Sepsis
Study of the Function of Cells Involved in Inflammation in the Lungs of Those With Acute Lung Injury and Sepsis
Acute lung injury (ALI) is an often deadly form of respiratory failure caused by inflammation. The widespread injury to the lungs involves a build-up of fluid in the lungs that results in damage to the lungs and a decreased…
- Trial name
- AMFAS (NCT01725061)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Emory University
Postoperative Pain
Hydromorphone and C-section
This study will investigate the dose of hydromorphone which will relieve the pain of women following a cesarean section when delivered directly in the area around the spinal cord (i.e., intrathecal injection).
- Trial name
- NCT01598545
- Testing
- Hydromorphone
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Emory University
Coronary Artery Disease
Assessment of Translesional Markers and Metabolomics
Blockages in the blood vessels of the heart are the main cause of chest pain, heart attacks, and sudden death. A cardiac catheterization, or injecting x-ray dye into the blood vessels of the heart and taking pictures, is…
- Trial name
- NCT00321139
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Emory University
HIV Infections
Kaletra-isentress Treatment Evaluation
This study will examine the effectiveness and safety of raltegravir (isentress) when used together with lopinavir/ritonavir (kaletra) for the treatment of HIV-infection.
- Trial name
- KITE (NCT00700115)
- Testing
- Kaletra + Isentress, Pre-study antiretroviral regimen
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Emory University
Aortic Coarctation
A Pilot Study of Thrombin Generation Changes in Neonates Undergoing Placement of a Blalock-Taussig Shunt
The primary goal of this investigation is to describe perioperative thrombin generation in neonates undergoing placement of a Blalock-Taussig (BT) shunt to better understand the coagulation changes that precipitate postoperative…
- Trial name
- NCT01340378
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Emory University
Acromegaly, Nonfunctioning Pituitary Tumor
Calcium Homeostasis in Acromegaly: Effect of Surgical/Medical Treatment and Comparison With Nonfunctioning Pituitary Tumors
The purpose of the study is to evaluate the Calcium homeostasis in adult patients with uncontrolled acromegaly. The measurements will be repeated 3-6 months after the treatment of acromegaly (surgical or medical).
- Trial name
- NCT01568359
- Where
- 2 sites in United States
- Volunteers
- 49 people
- Sponsor
- Emory University
Head and Neck Neoplasms, Cancer of the Head and Neck
A Study of Carboplatin, Cetuximab and RAD001 in Advanced Head and Neck Cancer
The purpose of this study is to test the drug RAD001 in combination with other chemotherapy drugs, Carboplatin and Cetuximab. Because RAD001 has not been used in this combination before, it is not clear which dose will be best…
- Trial name
- NCT01283334
- Testing
- Carboplatin, Cetuximab, RAD001
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Emory University
Mild Cognitive Impairment
A Rehabilitation Intervention for Amnestic Mild Cognitive Impairment
Mild Cognitive Impairment (MCI) is often an early manifestation of Alzheimer's disease (AD). The ability to identify MCI has led to hope that health prevention models might work in AD as they have in cancer and heart disease.
- Trial name
- NCT01283269
- Testing
- Memory Support System, Computer Training
- Where
- 3 sites in United States
- Volunteers
- 128 people
- Sponsor
- Emory University
Inflammatory Bowel Diseases, Skin Pigmentation
Weekly Vitamin D in Pediatric IBD
The purpose of this study is to determine whether weekly dosing of oral vitamin D3 is effective in correcting low vitamin D levels in children and adolescents with inflammatory bowel disease (also known as Crohn's disease and…
- Trial name
- NCT02076750
- Testing
- Vitamin D3 (cholecalciferol)
- Where
- 2 sites in United States
- Volunteers
- 34 people
- Sponsor
- Emory University
Precancerous Conditions
Phase I/II Study of Chemoprevention With EGFR and COX-2 Inhibitor
Evaluate effect on cells and patient response to study medications, assess side effects of these medications, and evaluate chemicals in cells that may tell how the drug works, before, and after receiving the study medications.
- Trial name
- NCT00314262
- Testing
- Erlotinib & Celecoxib
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Emory University
Feeding Disorders, Specific Phobia
D-cycloserine and Treatment of Feeding Disorders
The proposed study represents the first attempt to systematically investigate the use of DCS as an adjunct to behavioral intervention to address chronic food aversion through an randomized control drug trial in children treated…
- Trial name
- NCT01923896
- Testing
- Behavioral Intervention, d-cycloserine (DCS)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Emory University