Clinical trials: completed, sponsored by Emory University
Tuberculosis
Impact of Vitamin D Supplementation on Host Immunity to Mycobacterium Tuberculosis and Response to Treatment
Tuberculosis bacterium (TB) is a germ that can infect any part of the human body, especially the lungs. Vitamin D is a hormone present in humans that regulates blood electrolytes such as calcium and phosphate.
- Trial name
- NCT00918086
- Testing
- Vitamin D pill
- Where
- Georgia
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Emory University
Diabetes
Diabetes Group Visits
This pilot study aims to increase access to diabetes education by delivering it in a culturally-appropriate community setting and by involving different members of the diabetes care team including physicians, diabetes educators…
- Trial name
- NCT01000363
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Emory University
End-stage Renal Disease
Vitamin D and Arteriovenous Fistulae
Patients requiring hemodialysis following kidney failure need a form of dialysis vascular access in order to undergo the dialysis procedure. Dialysis vascular access dysfunction is an enormous clinical problem.
- Trial name
- NCT00912782
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Emory University
Tobacco Use Disorder
A Pilot Study of the Neural Correlates of Treatment Effect on Nicotine Craving
The purpose of this study is to gather pilot data to determine feasibility of and guide the development of a larger clinical trial investigating the effects of topiramate as an adjunct to nicotine replacement therapy and…
- Trial name
- NCT00208858
- Testing
- Topiramate
- Where
- United States
- Sponsor
- Emory University
Acute Myocardial Infarction
Phase 1 Study of Potential Anti-Inflammatory Effects of Glucose Control During Acute Myocardial Infarction.
The purpose of this study is to determine if intense control of high glucose levels in patients treated with angioplasty for heart attack has anti-inflammatory and anti-thrombotic effects.
- Trial name
- NCT00209144
- Testing
- Intensive insulin therapy
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- Emory University
Type 2 Diabetes
Insulin Detemir Versus NPH Insulin In Hospitalized Patients With Diabetes
High blood glucose levels in hospitalized patients with diabetes are associated with increased risk of medical complications. Improved glucose control with insulin injections may improve clinical outcome and prevent some of the…
- Trial name
- DEAN (NCT00590226)
- Testing
- Detemir + aspart insulin before meals, NPH insulin + regular insulin
- Where
- 2 sites in United States
- Volunteers
- 130 people
- Sponsor
- Emory University
Glaucoma
Interactive Study to Increase Glaucoma Adherence to Treatment
Study participants who receive the I-SIGHT intervention will have higher rates of glaucoma treatment compliance (e.g., medication-taking and refill compliance, return for clinical follow-up) and more positive eye health outcomes…
- Trial name
- I-SIGHT (NCT00794170)
- Testing
- Telephone and Print based intervention
- Where
- 2 sites in United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Emory University
Aortic Arch Hypoplasia or Atresia
Modified Perfusion for Neonatal Aortic Arch Reconstruction
Even though the lower part of the body does receive some blood supply during Cardiopulmonary Bypass(CPB) surgery, it may not be enough.
- Trial name
- NCT00490256
- Testing
- Modified Selective Cerebral Perfusion
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Emory University
Depression, Cardiovascular Diseases
Mechanisms Linking Depression to Cardiovascular Risk
To examine the role of depression on risk for cardiovascular disease in twins.
- Conditions
- Depression, Cardiovascular Diseases, Heart Diseases
- Trial name
- NCT00017836
- Sponsor
- Emory University
Pulmonary Hypertension
NO Need to Ventilate: A Trial of Non-invasive Inhaled Nitric Oxide in Persistent Pulmonary Hypertension of the Newborn
The primary objective of the trial is to determine the feasibility and clinical safety and efficacy of non-invasive inhaled nitric oxide in infants with PPHN without significant pulmonary +-parenchymal disease who would normally…
- Trial name
- NCT00139217
- Testing
- iNO, Non-invasive nitric oxide
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Emory University
Cancer
Analysis of Percutaneous Ablations for Cancer Treatment
This is a study involving patients with cancer who are referred by their treating physician for percutaneous locoregional therapies.
- Trial name
- NCT01563679
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Emory University
Liver Cancer, Portal Vein Thrombosis
TheraSpheres Treatment for Unresectable Hepatocarcinoma and Portal Vein Thrombosis
Therasphere will be administered via catheter through the Hepatic Artery to treat patients with Hepatocellular Carcinoma and Portal vein Thrombosis.
- Trial name
- NCT01556282
- Testing
- TheraSphere
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Emory University
Liver Cancer
Prospective Liver Study
This study is designed for patients diagnosed with Liver cancer to collect information about the relationship between types of liver cancer, methods of treatment and outcomes over time.
- Trial name
- NCT01539993
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Emory University
Sickle Cell Disease
Curative Versus Disease-Modifying Therapies in Children With Severe Sickle Cell Disease
The research proposed is a pilot study of pediatric and adolescent/young adult patients who have received the curative intervention (MSD-SCT), disease-modifying interventions (HU or CT) or SCC (control), with respect to three…
- Trial name
- SCD_Cross (NCT01369160)
- Testing
- Quality of Life measures
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- Emory University
Sickle Cell Disease
Analysis of T-Cell Immune Reconstitution Following Allogeneic Hematopoietic BMT for Severe SCD
In this study, patient blood samples from NMA transplants will be provided by Pittsburgh, and samples from myeloablative transplants will be provided by Atlanta (comparative controls).
- Trial name
- NCT00228631
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Emory University
Nausea and Vomiting
Ondansetron vs Prochlorperazine for Nausea and Vomiting in the Emergency Department
This study will compare the effect of prochlorperazine and ondansetron for the treatment of nausea and vomiting in the emergency department.
- Trial name
- NCT00590317
- Testing
- Prochlorperazine, Ondansetron
- Where
- 2 sites in United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Emory University
Surgery
Topical 0.4% Ketorolac and Vitreoretinal Surgery
To determine whether use of topical 0.4% ketorolac has any effect on pupil size during vitreoretinal surgery.
- Trial name
- NCT00576329
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Emory University
End Stage Renal Disease
Effects of Hemodialysis on the Sleep/Wake Cycle
The purpose of this study is to test a novel application of an existing treatment - using col dialysate (often used to treat hypotension) as opposed to warm dialysate (standard treatment) during hemodialysis for its ability to…
- Trial name
- NCT00460863
- Testing
- using cool versus warm dialysate during hemodialysis
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Emory University
Diabetes Mellitus, Heart Failure
Cost Effectiveness and Quality of Life in Heart Failure Patients With Diabetes
The purposes of this study are: 1. to develop and test an integrated self care intervention for Heart Failure (HF)patients with Diabetes (DM) for its effects on patient outcomes including health related quality of life (HRQOL)…
- Trial name
- QUALITYHF-DM (NCT01606085)
- Testing
- HF DM self care, Usual Care
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Emory University
HIV, Acquired Immunodeficiency Syndrome
Differences in Response to the Flu Vaccine Among Adults With HIV and Without HIV in Uganda
To use a systems biological approach to study the molecular signatures of innate and adaptive responses to vaccination in a HIV infected versus uninfected adult population in Kampala, Uganda.
- Conditions
- HIV, Acquired Immunodeficiency Syndrome, Influenza
- Trial name
- NCT01916759
- Testing
- Seasonal trivalent inactivated influenza vaccine (Vaxigrip®)
- Where
- Uganda
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Emory University