Clinical trials: completed, sponsored by Emory University
Raynaud's Syndrome
Botulinum Toxin in the Treatment of Raynaud's
The investigators are studying a medical condition known as Raynaud's Phenomenon (RP). RP is a painful condition in which cold surroundings or stressful events trigger pain, a cold sensation, and in severe cases, sores and ulcers…
- Trial name
- NCT01233999
- Testing
- botulinum toxin A
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Emory University
Type 2 Diabetes, Inpatient Hyperglycemia
Basal Bolus Insulin Versus SSRI in Type 2 Diabetes Undergoing General Surgery
High blood glucose levels in surgical patients with diabetes are associated with increased risk of medical complications and death.
- Trial name
- RABBIT 2-SX (NCT00596687)
- Testing
- Insulin glargine, Regular insulin, Insulin glulisine
- Where
- 2 sites in United States
- Volunteers
- 234 people
- Sponsor
- Emory University
Coronary Artery Disease, Chronic Obstructive Pulmonary Disease
Inflammatory Biomarkers Predict Pulmonary Outcomes in Coronary Artery Bypass Grafting
The primary objective of this pilot study is to identify and quantify inflammatory and genetic markers from bronchoalveolar lavage fluid (BALF) and serum in patients with a history of chronic obstructive pulmonary disease (COPD)…
- Trial name
- CABG BALF (NCT01366469)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Emory University
Congenital Disorders
Multisite Feeding Study: Home Surveillance and Feeding Strategies in Infants With Complex Single Ventricle
This study will assess 75-100 patients for feeding issues following surgery for single ventricle.
- Trial name
- NCT00257517
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Emory University
End-stage Renal Disease
The Effects of Cool Dialysate on the Sleep/Wake Cycle in Patients on Chronic Hemodialysis - "The Sleep Cool Study"
A major component of this study is to test a novel application for a safe, non-pharmacologic, cost-effective intervention that is already in use in clinical practice - using cool dialysate during hemodialysis to help stabilize…
- Trial name
- NCT00218790
- Testing
- Cool Dialysate
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- Emory University
Epilepsy, Depressive Symptoms
Preventing Depression in People With Epilepsy: an Extension of Project UPLIFT
Project UPLIFT, a home-based treatment for depression in people with epilepsy, was designed to be delivered to groups by telephone or Web.
- Conditions
- Epilepsy, Depressive Symptoms, Depression, Seizure Disorder
- Trial name
- NCT01941706
- Testing
- Project UPLIFT
- Where
- 4 sites in United States
- Volunteers
- 130 people
- Sponsor
- Emory University
Hyperglycemia
Insulin Infusion in the Hospital Wards
Increasing evidence from clinical studies in Intensive Care Unit (ICU) settings indicates that insulin infusion can improve outcome measures for patients with hyperglycemia (high blood sugar) independent of a previous diagnosis…
- Trial name
- NCT00412347
- Testing
- Insulin Drip Therapy
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Emory University
Asthma
Redox Determinants of Severe Asthma (a Substudy of the Severe Asthma Research Program)
Hypotheses: 1) Airway pH regulation is abnormal in severe asthma; 2) In severe asthma, there is formation of cytotoxic nitrogen oxides and loss of beneficial nitrogen oxides in the airways
- Trial name
- SARP (NCT00590005)
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Emory University
Sepsis
Pharmacokinetic and Pharmacodynamic Evaluation of Doripenem in Critically Ill Trauma Patients
The study hypothesis is to measure how the drug doripenem is cleared from the body of critically ill trauma patients. The investigators will measure blood drug concentrations and calculate how much the drug distributes in the…
- Trial name
- NCT01027897
- Testing
- Doripenem
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Emory University
Major Depressive Disorder
Imaging Predictors of Treatment Response in Depression
While there are many effective options for treating a major depressive episode, there are no clinical markers that predict the likelihood of remission with an initial trial of either an antidepressant medication or psychotherapy.
- Trial name
- NCT00367341
- Testing
- escitalopram, Cognitive Behavioral Therapy (CBT)
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Emory University
Type 1 Diabetes Mellitus
Insulin Delivery Using Microneedles in Type 1 Diabetes
The goal of this study is to determine if microneedles can effectively and painlessly deliver insulin to children and young adults with type 1 diabetes.
- Trial name
- NCT00837512
- Testing
- Microneedle, Subcutaneous insulin catheter
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Emory University
Atherosclerosis
Evaluation of Atorvastatin on Atherosclerosis Composition
The purpose of this study is to evaluate the effects of Atorvastatin on the coronary atherosclerosis plaque morphology.
- Trial name
- NCT00576576
- Testing
- Atorvastatin
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Emory University
Degenerative Disc Disease
Comparison of IDD Therapy and Non-surgical Treatment for Low Back Pain Caused by Degenerative Disc Disease
This study is looking at a new machine called the Accu-Spina which administers internal disc decompression by following a computer program.
- Trial name
- NCT00165893
- Testing
- Accu-Spina Device/IDD therapy, Physical Therapy
- Volunteers
- 50 people
- Sponsor
- Emory University
Severe Traumatic Brain Injury
Discrete Hypothermia in the Management of Traumatic Brain Injury
The primary goal of this project is to demonstrate the feasibility and clinical benefits of a new rapid treatment for secondary treatment for secondary brain injury called Discrete Cerebral Hypothermia System by CoolSystems…
- Trial name
- NCT00676104
- Testing
- CoolSystems Discrete Cerebral Hypothermia System
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Emory University
Coronary Disease
A Randomized Controlled Trial to Improve Medication Compliance Among Patients With Coronary Heart Disease
Coronary heart disease (CHD) is the most common cause of death in the United States. A common term for CHD is "blocked arteries." People with CHD or "blocked arteries" often have high blood pressure, high cholesterol, or…
- Trial name
- NCT00208832
- Testing
- Graphic medication schedule (Pill card), Refill reminder postcard
- Where
- United States
- Volunteers
- 440 people
- Sponsor
- Emory University
Congestive Heart Failure
Stimulus Intensity in Left Ventricular Leads
Cardiac resynchronization therapy (CRT) is a device implanted to improve the function of some people's hearts. CRT involves the placement of 3 wires in the heart through a vein near the front of your left or right shoulder into…
- Trial name
- SILVeR-CRT (NCT01060449)
- Testing
- LV stimulus intensity
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Emory University
Familial Hypercholesterolemia
Effects of Low-density Lipoprotein (LDL) Apheresis on Inflammatory and Lipid Markers
The primary objective of this study is to measure how LDL apheresis affects levels of inflammatory and cholesterol markers in human beings.
- Trial name
- INFLAME (NCT01138371)
- Testing
- LDL Apheresis
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Emory University
HIV Prevention
S.T.A.R.S.: Sistas Talking About Real Solutions
STARS: Sistas Talking About Real Solutions is a health education intervention for African-American women, ages 18-29 aimed at reducing their risk for HIV.
- Trial name
- STARS (NCT01028157)
- Testing
- STARS: Sistas Talking About Real Solutions, General Health & Nutrition
- Where
- United States
- Volunteers
- 855 people, healthy volunteers welcome
- Sponsor
- Emory University
Short Bowel Syndrome
Mechanisms of Adaptation in Human Short Bowel Syndrome
This is an observational, natural history trial of mechanisms of gut adaptation in adult short bowel syndrome (SBS). Patients with SBS (< 200 cm small bowel ± colon) will be studied initially 2-9 months after the last small bowel…
- Trial name
- NCT00248573
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Emory University
Domestic Violence, Post-Traumatic Stress Disorder
Mental Health Symptoms and Intimate Partner Violence
Using a touch screen computer, the researchers are screening emergency department patients for intimate partner violence and mental health issues.
- Conditions
- Domestic Violence, Post-Traumatic Stress Disorder, Depression
- Trial name
- NCT00166075
- Testing
- Computer screen with community resource printout
- Where
- United States
- Volunteers
- 569 people, healthy volunteers welcome
- Sponsor
- Emory University