Clinical trials: completed, sponsored by Emory University
Malignancy, Bone Marrow Transplantation
Rifaximin for Preventing Acute Graft Versus Host Disease (AGVHD)
Acute graft versus host disease is a frequent and often life threatening complication of allogeneic blood and marrow transplantation. The bacteria that normally reside in the intestine play a critical role in its development.
- Trial name
- NCT00967096
- Testing
- Rifaximin
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Emory University
Congenital Heart Disease
Neurodevelopmental Outcomes in Hypoplastic Left Heart Syndrome
There have been many improvements in the care of children with hypoplastic left heart syndrome (HLHS). This has helped these children survive longer.
- Trial name
- NCT00399555
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Emory University
Pediatric, Cardiac Surgery
Cardiopulmonary Circuits in the Pediatric Population
During open-heart surgery, blood flow is supported by a heart-lung machine that both pumps the blood and gives it oxygen. A problem associated with a heart-lung machine is the damage to some of the blood caused by protein in the…
- Trial name
- NCT00208728
- Testing
- PC/SMART cardiopulmonary bypass circuit, PMEA modified cardiopulmonary bypass circuit, Standard of care uncoated cardiopulmonary bypass circuit
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Emory University
Children With Heart Transplants
Tissue Doppler Echo Imaging of Heart Function After Transplant
There are many children born with Congenital Heart Disease. Many of these children have to undergo surgical procedures to correct the problem. Some patients must eventually get a new heart.
- Trial name
- NCT00208650
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Emory University
Congenital Heart Disease
Retrospective Pulmonary Valve Replacement Imaging
This is a retrospective chart review examining children and adults with history of Tetralogy of Fallot or pulmonary stenosis who have undergone subsequent pulmonary valve replacement.
- Trial name
- NCT00446108
- Where
- 2 sites in United States
- Volunteers
- 153 people
- Sponsor
- Emory University
Colorectal Adenomatous Polyps
Calcium and Vitamin D vs Markers of Adenomatous Polyps
The purpose of this study is to test whether calcium and/or vitamin D supplementation favorably affects a set of biomarkers of risk for colon cancer in persons who are at higher than average risk for colon cancer (ie, have…
- Trial name
- CaDvMAP (NCT00208793)
- Testing
- Calcium and vitamin D3 combined, Calcium, Vitamin D3
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Emory University
Heart Disease, Congenital, Pulmonary Valve Replacement
Outcomes Following Pulmonary Valve Replacement in Adults
One of the most common residual lesions in adult survivors of pediatric cardiac surgery is pulmonary valve disease, particularly regurgitation.
- Trial name
- NCT00276237
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Emory University
Endocarditis
Outcomes Following Medical or Surgical Management of Endocarditis
Infective endocarditis is a rare disease, and while there have been several large reviews of the incidence of endocarditis in the pediatric patient population, relatively little has been published regarding the short and…
- Trial name
- NCT00166023
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Emory University
Kidney Transplant, Immunology
Protective Immunity Project 02
Influenza (Flu) vaccine is recommended for kidney transplant patients who are at least 6 months post-transplant. The influenza vaccine stimulates the immune system to builds protective antibodies against the flu virus.
- Conditions
- Kidney Transplant, Immunology, Immunosuppression
- Trial name
- PIP-02 (NCT00833651)
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Emory University
Kidney Transplantation, Immunity
Protective Immunity Project 01
Patients who undergo kidney transplant must take medications to prevent organ rejection. There are standard immunosuppressant medications such as prednisone, tacrolimus (Prograf), mycophenolate mofetil(Cellcept) or sirolimus…
- Conditions
- Kidney Transplantation, Immunity, Immunosuppression
- Trial name
- PIP-01 (NCT00788021)
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Emory University
HIV Prevention, HIV Infections
HIV- Risk Reduction Behavioral Intervention for Commercial Sex Workers in Yerevan Armenia
This pilot study will test the efficacy of a behavioral intervention in reducing HIV related risk behaviors among sex workers in Yerevan, Armenia.
- Trial name
- NCT00886561
- Testing
- HIV risk reduction intervention
- Where
- Armenia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Emory University
Odontogenic Infection
A Comparison of Redrubber Versus Penrose Drains
All patients presenting to Grady Memorial Hospital with an odontogenic (dental) infection that requires admission to the hospital and incision and drainage will be eligible for inclusion in this pilot study.
- Trial name
- redrubber (NCT00645957)
- Testing
- penrose drain, red rubber drain
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Emory University
COPD
Study on COPD Corticosteroid-induced Hyperglycemia on Clinical Outcome in Patients With COPD
Hyperglycemia is a common complication of corticosteroid (cortisone) therapy. It is estimated that more than a third of patients with chronic pulmonary disease (COPD) exacerbation (16).
- Trial name
- NCT00605007
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- Emory University
Temporomandibular Joint Dysfunction
A Comparison of Arthrocentesis, Arthroscopy and Arthroplasty in the Treatment of Temporomandibular Joint Dysfunction
Many patients suffer from a disorder known as temporomandibular joint dysfunction. This disorder has jaw joint pain and limited function as key elements.
- Trial name
- TMJ (NCT00636727)
- Testing
- arthrocentesis, arthroscopy, arthroplasty
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Emory University
Non-alcoholic Fatty-liver Disease
Effects of Dietary Fructose Reduction in Children With Hepatic Steatosis
Primary Objectives: 1. To determine whether a 4 week reduction in dietary fructose intake improves hepatic steatosis in overweight children who have a baseline high fructose consumption and hepatic steatosis. 2.
- Trial name
- Sweet Bev (NCT01188083)
- Testing
- Fructose Drink, Glucose Drink
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Emory University
Breast Cancer
Comparison Study of Breast Tomosynthesis Slice Thicknesses
Early diagnosis is one of the most important factors in the survival of patients diagnosed with breast cancer. To aid in the early detection of breast cancer, a new technology, called tomosynthesis imaging is being developed.
- Trial name
- NCT00957567
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Emory University
Hyperglycemia, Diabetes
Diabetes in the Perioperative Period
High blood glucose levels in surgical patients with and without diabetes are associated with increased risk of medical complications and death.
- Trial name
- NCT00738114
- Where
- United States
- Volunteers
- 3,184 people
- Sponsor
- Emory University
Spinal Cord Injury
Intermittent Hypoxia Elicits Prolonged Restoration of Motor Function in Human SCI
The goal of the study is to determine whether repeatedly breathing low oxygen levels for brief periods (termed intermittent hypoxia) will improve limb function after spinal cord injury.
- Trial name
- NCT01272349
- Testing
- Acute intermittent hypoxia, Room air
- Where
- 2 sites in United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Emory University
Catheter-Related Infections, Bacteremia
Comparison of Infection Rates Among Patients Using Two Catheter Access Devices
Intravenous catheters are placed in nearly every hospitalized patient. These catheters, since they are breaks in skin integrity, are potential sources of infection that occur in the bloodstream.
- Trial name
- NCT00965198
- Where
- 2 sites in United States
- Volunteers
- 10,000 people
- Sponsor
- Emory University
Diabetes, Hyperglycemia
Basal/Bolus Versus Sliding Scale Insulin In Hospitalized Patients With Type 2 Diabetes
High blood glucose levels in hospitalized patients with diabetes are associated with increased risk of medical complications. Improved glucose control with insulin injections may improve clinical outcome and prevent some of the…
- Trial name
- NCT00394407
- Testing
- sliding scale regular insulin, glargine basal insulin and glulisine prandial insulin
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Emory University