Clinical trials: completed, sponsored by Emory University
Blood Coagulation Disorders
Thrombin Generation in Neonates
Children having open heart surgery must be on a heart-lung bypass machine. It is essential that the blood in the heart-lung machine does not clot. This is accomplished by giving a drug called heparin, a "blood thinner".
- Trial name
- NCT00165906
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Emory University
Sleep, Pain
Acupuncture for Pain and Sleep Disturbance in Knee Osteoarthritis
The hypotheses of this study are: In the older population with knee OA, When acupoints are chosen for both sleep and pain, there are additive effects on sleep improvement and pain relief (i.e. no interaction).
- Trial name
- NCT00694447
- Testing
- Acupuncture
- Where
- United States
- Sponsor
- Emory University
Mandibular Injuries
Champy Versus AO for Mandible Fractures
Patients who sustain a broken lower jaw have traditionally been treated in one of three ways. The first involves having their teeth and jaws being wired together for a period of 4 to 6 weeks in order to allow the broken jaw to…
- Trial name
- Mand (NCT00628849)
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Emory University
Children With Heart Defects
Heparin Responses in Pediatric Patients Undergoing Cardiopulmonary Bypass.
Heparin is an anticoagulant or "blood thinner". Heparin is always given to patients undergoing open-heart surgery to prevent blood from clotting when a patient is placed on the heart-lung machine.
- Trial name
- NCT00166140
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Emory University
Primary Condition: Heart Defects Requiring Surgery With CPB
Heparin Management During Cardiopulmonary Bypass in Children
We propose a comparison between between our standard ACT based heparin management protocol for children undergoing CPB and a patient-specific heparin concentration-based heparin management protocol.
- Trial name
- NCT00146653
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Emory University
Depression, Panic Disorder
Evaluating the Effects of Stress in Pregnancy
This study will evaluate pregnant women with a past or current diagnosis of depression or anxiety to gain a better understanding of how these disorders can affect an infant's development, both during and after pregnancy.
- Conditions
- Depression, Panic Disorder, Generalized Anxiety Disorder, Post-Traumatic Stress Disorder
- Trial name
- NCT00525226
- Where
- United States
- Volunteers
- 1,431 people, healthy volunteers welcome
- Sponsor
- Emory University
Cardiopulmonary Bypass
Thrombin Generation in Neonatal Plasma After Cardiopulmonary Bypass
The primary goal of this investigation is to determine the ability of recombinant activated factor VII (rFVIIa) and prothrombin complex concentrate (PCC) to improve thrombin generation in neonatal plasma after CPB.
- Trial name
- NCT01352143
- Testing
- Recombinant activated factor VII, Prothrombin Complex Concentrate
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Emory University
Pancreatic Insufficiency
Pancreatic Insufficiency Secondary to Tobacco Exposure
Pancreatic insufficiency is a condition in which there is a decrease in the production and release of enzymes made in the pancreas, which causes nutrient malabsorption.
- Trial name
- NCT01988350
- Where
- United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Emory University
Breast Cancer
An Evaluation of Stereoscopic Digital Mammography for Earlier Detection of Breast Cancer and Reduced Rate of Recall
The primary goal of this study is to compare, within a clinical screening setting, the performance of stereoscopic digital mammography with standard (non-stereo) digital mammography in the detection of abnormalities in the…
- Trial name
- NCT00208871
- Testing
- Stereoscopic Digital Mammography
- Where
- United States
- Volunteers
- 1,467 people, healthy volunteers welcome
- Sponsor
- Emory University
Sexually Transmitted Diseases
HIV Prevention for African American Teens
AFIYA aims to reduce both the risk of Sexually Transmitted Infections (STIs) and HIV in young African American females through a culturally and gender appropriate intervention (group sessions) coupled with an individualized HIV…
- Trial name
- NCT00279799
- Testing
- Afiya HIV Prevention Intervention
- Where
- 3 sites in United States
- Volunteers
- 701 people, healthy volunteers welcome
- Sponsor
- Emory University
Chronic Disease, Mental Illness
Medical Self-Management for Improving Health Behavior Among Individuals in Community Mental Health Settings
This study will evaluate the effectiveness of a medical illness self-management program in improving the health and health behavior of people who are receiving care at a community mental health center.
- Trial name
- NCT00380536
- Testing
- Peer-Led Health Education Class
- Where
- 2 sites in United States
- Volunteers
- 111 people
- Sponsor
- Emory University
Major Depressive Disorder
Treatment of Reduced Heart Rate Variability Associated With Major Depression With Electroconvulsive Therapy
The purpose of this study is to evaluate alterations in sympathetic tone in patients with major depression with and without ischemic heart disease and then to reevaluate these patients after 8 treatments with electroconvulsive…
- Trial name
- NCT00209066
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Emory University
Healthy
Infectivity of Norovirus in Shellfish Treated With High Hydrostatic Pressure Processing-Human Challenge Study
Norwalk virus and related "Norwalk-like viruses" are the most common cause of outbreaks of stomach sickness (nausea, vomiting, diarrhea) in older children and adults in the United States.
- Trial name
- Shellfish (NCT00674336)
- Testing
- High Hydrostatic Pressure Processing
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Emory University
Healthy
Infectivity of Norovirus in Groundwater-Human Challenge Study
Norwalk virus and related "Norwalk-like viruses" are the most common cause of outbreaks of stomach sickness (nausea, vomiting, diarrhea) in older children and adults in the United States.
- Trial name
- NCT00313404
- Testing
- Safety tested norovirus inoculum
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Emory University
HIV Infections
IMARA, Adapting SiHLE for Detained African American Adolescent Females
The IMARA Program will test the efficacy of a multi-session HIV Prevention program, adapted from an existing program(SiHLE), for incarcerated African American adolescent females.
- Trial name
- IMARA (NCT00746369)
- Testing
- IMARA HIV Prevention Intervention
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Emory University
Lung Cancer
Amino Acid Tracer (FACBC) Positron Emission Tomography for Lung Nodule
This study will look at how the [18]FACBC goes into the lung nodules. This will hopefully lead to the development of better imaging techniques to look at lung nodules.
- Trial name
- SPN (NCT01502670)
- Testing
- 18F-FACBC Radiotracer
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Emory University
Mental Disorders
Improving Primary Care in Patients With Mental Disorders
This study will determine the effectiveness of medical case management in improving the medical care of people with mental disorders or substance abuse problems.
- Trial name
- NCT00183313
- Testing
- Nurse case management, Usual care
- Where
- 2 sites in United States
- Volunteers
- 407 people
- Sponsor
- Emory University
HIV Infections, Sexually Transmitted Diseases
HORIZONS HIV Intervention
The Horizons Program will test the efficacy of a multi-session HIV prevention program for African American female teens attending reproductive health clinics in Atlanta, GA.
- Trial name
- HORIZONS (NCT00633906)
- Testing
- HORIZONS HIV Intervention, enhanced standard-of-care
- Where
- 3 sites in United States
- Volunteers
- 715 people, healthy volunteers welcome
- Sponsor
- Emory University
Cardiovascular Diseases
Predictive Medicine Research. (PRE MED)
Principal Investigator: Arshed A. Quyyumi, MD To establish normal values by age, race, and gender of novel markers of risk in healthy subjects necessary to predict precise risk of cardiovascular disease in an individual.
- Trial name
- NCT00336570
- Where
- United States
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Emory University
Hypertension
Effects of Tetrahydrobiopterin on Blood Pressure
Tetrahydrobiopterin (BH4) is a cofactor for the nitric oxide (NO) synthase enzymes, such that its insufficiency results in uncoupling of the enzyme, leading to release of superoxide rather than NO in disease states, including…
- Trial name
- NCT00208780
- Testing
- Tetrahydrobiopterin
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Emory University