Clinical trials: completed, sponsored by Emory University
Atherosclerosis, Endothelial Dysfunction
Predictive Medicine Research
To establish normal values by age, race, and gender of novel markers of risk in healthy subjects necessary to predict precise risk of cardiovascular disease in an individual
- Trial name
- NCT00384761
- Where
- United States
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- Emory University
Endothelial Dysfunction
To Compare the Ischemic Pre-conditioning and Post-conditioning on Reperfusion Injury in Humans.
Reperfusion Injury occurs by the sudden blood flow to the injured and ischemic myocardium during restoration of blood flow either by Mechanical revascularization or thrombolysis.
- Trial name
- NCT00385151
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Emory University
Metabolic Syndrome
Partnership Programs to Reduce Cardiovascular Disparities- Morehouse- Emory Partnership
The theme of this Morehouse-Emory Partnership Program focuses on elucidating the etiologic basis of ethnic differences in obesity-related CVD and discovering new intervention strategies to ameliorate CV health in all communities.
- Trial name
- Meta-Health (NCT00336869)
- Where
- 2 sites in United States
- Volunteers
- 680 people, healthy volunteers welcome
- Sponsor
- Emory University
Obesity
Effect of a Mediterranean Diet and Omega-3 Fatty Acids on Oxidative Stress and Endothelial Progenitor Cells (EPC's)
Problem of Interest: A typical American diet that is high in an intake of fats (especially saturated fats and cholesterol) is known to lead to high blood levels of cholesterol, hardening of the arteries, and increases the risk of…
- Trial name
- NCT00166088
- Testing
- Mediterranean Diet, Mediterranean Dietary Supplement
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Emory University
Myocardial Infarction, Coronary Artery Disease
Intra-coronary Infusion of Bone Marrow Derived Autologous CD34+ Selected Cells in Patients With Acute Myocardial Infarction
Following a Heart attack the acute loss of heart muscle cells results in a cascade of events causing an immediate decrease in cardiac function that has the potential to persist long term.
- Trial name
- AMR-1 (NCT00313339)
- Testing
- Intra-coronary infusion
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Emory University
Obesity, Cardiovascular Diseases
Comparison of Workplace Obesity Management Programs
The purpose of this study is to design and demonstrate the feasibility of implementing moderate and intensive environmental obesity prevention programs at major worksites.
- Conditions
- Obesity, Cardiovascular Diseases, Heart Diseases
- Trial name
- NCT00122928
- Testing
- Diet, Exercise, Environmental Obesity Program - Healthy Culture
- Volunteers
- 5,124 people
- Sponsor
- Emory University
Behavioral Resilience, Biological Resilience
Cognitively-Based Compassion Training and Mindfulness Attention Training Program
This project will explore the effect of Cognitively-Based Compassion Training or mindfulness training on behavior and saliva stress hormones in elementary school-age children.
- Trial name
- NCT01592188
- Testing
- Cognitively-Based Compassion Training (CBCT), Mindfulness training
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Emory University
Diabetes
Diabetes in the Elderly: Retrospective Study
Diabetes is highly prevalent in the elderly, afflicting about 20% of older adults aged 65-75 years and 40% of adults >80years of age. Management of hyperglycemia is challenging in the geriatric population in long-term facilities.
- Trial name
- NCT01104168
- Where
- 2 sites in United States
- Volunteers
- 1,409 people, healthy volunteers welcome
- Sponsor
- Emory University
Melasma
Treatment of Melasma With Jessner's Solution vs. Trichloroacetic Acid
Melasma is an acquired discoloration of the skin characterized by brown patches. Chemical peels using agents such as Jessner's solution and trichloroacetic acid (TCA) are commonly used to treat melasma.
- Trial name
- NCT00166192
- Testing
- Jessner's solution chemical peel, Trichloroacetic acid chemical peel
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Emory University
Pregnancy, Bipolar Disorder
Bipolar Disorder (BPD) in Pregnancy: Predictors of Morbidity
Very little is known about the impact of pregnancy and the postpartum period on BPD. As a result, the investigators have little evidence on which to base treatment guidelines.
- Trial name
- NCT00864370
- Where
- United States
- Volunteers
- 237 people
- Sponsor
- Emory University
Major Depressive Disorder
Characterizing Psychological Consequences of Childhood Trauma
This study will characterize the mental health consequences of early-life trauma.
- Trial name
- NCT00209105
- Testing
- DEX-CRF stimulation test, Psychosocial stress induction, Brain imaging of sad mood , self-reference, reward
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Emory University
Ketosis Prone Diabetes, Diabetic Ketoacidosis
Ketosis Prone Diabetes in African-Americans
Over 50% of obese African-Americans (AA) presenting with newly diagnosed, severe hyperglycemia and/or unprovoked diabetic ketoacidosis (DKA) display clinical, metabolic, and immunogenetic features of type 2 diabetes.
- Conditions
- Ketosis Prone Diabetes, Diabetic Ketoacidosis, Severe Hyperglycemia
- Trial name
- NCT00426413
- Testing
- pioglitazone
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Emory University
Senile Dementia, Alzheimer Type, Dementia, Alzheimer Type
A Comparison of Two Standard Therapies in the Management of Dementia With Agitation
The purpose of this study is to determine whether an antipsychotic medication alone or an antipsychotic medication in combination with divalproex is the most effective and safest way to treat agitation in elderly patients with…
- Conditions
- Senile Dementia, Alzheimer Type, Dementia, Alzheimer Type, Alzheimer Disease, Dementia
- Trial name
- NCT00208819
- Testing
- risperidone, quetiapine, olanzapine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Emory University
Social Anxiety Disorder (SAD)
Nefazodone in the Treatment of Social Phobia
The purpose of this study is to determine the effectiveness of nefazadone in patients with social anxiety disorder (SAD).
- Trial name
- NCT00231348
- Testing
- Nefazodone
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Emory University
Congenital Disorders
Effects of Beta-adrenergic in Adults w/Transposition of Great Arteries on Systemic Ventricular Function
The purpose of this chart review study is to examine the effects of beta -adrenergic blocking agents on systemic ventricular dimensions, systemic atrioventricular valve function and exercise tolerance in patients with…
- Trial name
- NCT00313352
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Emory University
Generalized Anxiety Disorder, Anxiety
Muscle Relaxation Therapy With Odorant Cue
A novel procedure for generalized anxiety disorder where an odorant cue is paired with the state of deep relaxation during training.
- Trial name
- NCT00208910
- Testing
- Odorant Cue
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Emory University
Major Depression, Mental Health
Provigil in Conjunction With SSRIs for the Treatment of Mild or Moderate Depression With Attendant Symptoms of Sleepiness and Fatigue.
The main purpose of this study is to determine if Provigil® (modafinil) at a dose of 200 mg once daily is safe and effective for treating symptoms of sleepiness and fatigue associated with Major Depressive Disorder when added to…
- Trial name
- NCT00208715
- Testing
- Provigil
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- Emory University
Social Anxiety Disorder
Study To Evaluate The Effects Of Gabitril™ In Patients With Social Anxiety Disorder
The main purpose of this study is to determine how safe and effective Gabitril is for outpatients with Social Anxiety Disorder (SAD).
- Trial name
- NCT00208741
- Testing
- Gabitril
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Emory University
HIV Infections
A Pharmacokinetic (PK) Study of a Combination of Indinavir, Ritonavir, and Amprenavir
When individuals who are infected with HIV are started on treatment with HIV medications, the effect of these drugs only lasts for a limited period of time, often because of development of drug resistance by the HIV virus.
- Trial name
- NCT00148785
- Testing
- Indinavir/Ritonavir/Fosamprenavir
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Emory University
Major Depressive Disorder
Does Fluoxetine Have an Effect on the CNS CRF Systems in Women Abused in Childhood?
The primary objective of this project is to determine whether treatment with the SSRI, fluoxetine versus placebo reverses alterations in the central CRF system induced by early life stress experiences (i.e.
- Trial name
- NCT00208897
- Testing
- Fluoxetine
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Emory University