Clinical trials: completed, sponsored by Emory University
Sepsis
Novel Sepsis Sub-phenotypes Based on Trajectories of Vital Signs
Sepsis is a dysregulated host response to infection resulting in organ dysfunction. Over the past three decades, more than 30 pharmacological therapies have been tested in >100 clinical trials and have failed to show consistent…
- Trial name
- NCT05826223
- Testing
- Implementation and evaluation of a sepsis sub-phenotyping algorithm
- Where
- 4 sites in United States
- Volunteers
- 1,916 people
- Sponsor
- Emory University
Asthma in Children
Symptom Clusters in Children With Exacerbation-prone Asthma
Pediatric participants with exacerbation-prone asthma will receive an intramuscular injection of triamcinolone acetonide and will be followed for 48 weeks.
- Trial name
- NCT04002362
- Testing
- Triamcinolone Acetonide
- Where
- 2 sites in United States
- Volunteers
- 68 people
- Sponsor
- Emory University
Cholera
Immunologic Responses to a Live Attenuated Oral Cholera Vaccine
The primary objective of this study is to evaluate the antibody response to the cholera vaccine, Vaxchora®, in healthy subjects.
- Trial name
- NCT03251495
- Testing
- Vaxchora
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Emory University
Non-cystic Fibrosis Bronchiectasis
Trikafta for Patients With Non-cystic Fibrosis Bronchiectasis
Study participants with non-cystic fibrosis bronchiectasis will be given Trikafta for four weeks. The researchers will monitor clinical endpoints, quality of life, and weight.
- Trial name
- NCT05743946
- Testing
- Trikafta
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Emory University
Healthy
Aldena STAR Particles
The objective of this study is to find out the best method of applying STAR particles to the skin. STAR particles are very small particles with microneedles on the surface that can increase and create small punctures in the skin.
- Trial name
- NCT06004973
- Testing
- STAR Particles, Gel without STAR Particles
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Emory University
Cardiovascular Disease, Coronary Artery Disease
Smartphone Delivered In-home Cardiopulmonary Rehabilitation
The goal of this study is to determine if a remote cardiac or pulmonary rehabilitation program delivered via a smartphone application and regular telephone calls will lead to improved delivery of cardiac rehabilitation compared…
- Trial name
- NCT02791685
- Testing
- MULTIFIT Cardiac Rehabilitation, Movn Pulmonary Rehabilitation, Standard of Care Cardiac Rehabilitation
- Where
- United States
- Volunteers
- 258 people
- Sponsor
- Emory University
Mild Cognitive Impairment
Keeping on Course: A Communication-Focused Psychoeducational Program
The goal of Keeping on Course is to develop and test a psychoeducation program to provide dyads facing mild cognitive impairment (MCI) with communication skills and strategies that will establish or restore a sense of agency as…
- Trial name
- NCT05423912
- Testing
- Keeping on Course Program
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Emory University
Hospital Infection, Standardized Antibiotic Prescribing Ratio (SAR)
InPART RX - Epicenters
InPART Rx is a collaborative research study to measure the impact of a planned quality improvement initiative to reduce unnecessary antibiotic prescribing by the Hospital Medicine Service through a process of receiving…
- Trial name
- InPART RX (NCT07368660)
- Testing
- Messaging Hospitalists, Usual Care
- Where
- 4 sites in United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Emory University
Advanced Pancreatic Adenocarcinoma, Metastatic Pancreatic Adenocarcinoma
Paricalcitol and Hydroxychloroquine in Combination With Gemcitabine and Nab-Paclitaxel for Advanced Pancreatic Cancer
This phase II trial investigates how well paricalcitol and hydroxychloroquine work when combined with gemcitabine and nab-paclitaxel in treating patients with pancreatic cancer that has spread to other places in the body…
- Conditions
- Advanced Pancreatic Adenocarcinoma, Metastatic Pancreatic Adenocarcinoma, Stage IV Pancreatic Cancer AJCC v8
- Trial name
- NCT04524702
- Testing
- Gemcitabine, Hydroxychloroquine, Nab-paclitaxel
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- Emory University
Trigger Finger
Trigger Finger Trial
Trigger finger is a common condition of the hand caused by the thickening of the A1 pulley or flexor tendon that alters the way in which the flexor tendon glides within the tendon sheath.
- Trial name
- NCT05251428
- Testing
- Excision of the A1 pulley, Incision of the A1 pulley in the standard fashion
- Where
- 6 sites in United States
- Volunteers
- 80 people
- Sponsor
- Emory University
Vaccine Response
Systems Biological Assessment of Statin Effect on Vaccine Responses
This study is being done to answer the question: Does the use of statin lipid-lowering medication change the effect of influenza vaccine? The research team will use the knowledge gained from answering this question to understand…
- Trial name
- NCT06024096
- Testing
- Atorvastatin, Quadrivalent seasonal influenza vaccine
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Emory University
Coronary Artery Disease
The MATCH Investigation: CT Myocardial Perfusion and CT-FFR vs PET MPI
The overall goal of this project is to compare the absolute quantification of myocardial perfusion done by using CT myocardial perfusion imaging (CT-MPI) and the coronary flow measured by using CT Fractional Flow Reserve analysis…
- Trial name
- NCT04316676
- Testing
- PET-MPI Protocol, CT-MPI, Coronary CT angiography (CCTA) for CT-FFR calculation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Emory University
Autism Spectrum Disorder
Promoting Transactional Supports to Optimize Social Communication Outcomes for Infants and Their Families
This early treatment project is designed to address two significant public health challenges - the need for validated, manualized, treatments for young children with Autism Spectrum Disorder (ASD) that are cost-efficient and…
- Trial name
- NCT03307057
- Testing
- Social Communication Growth Charts (SCGC), Parent-Implemented (P-I) Condition, Clinician-Implemented (C-I) Condition
- Where
- United States
- Volunteers
- 269 people
- Sponsor
- Emory University
Sickle Cell Disease
Development and Adaptation of I-STRONG for SCD
This study develops and tests the feasibility and acceptability of an adapted intervention, Integrative Strong Body and Mind Training (I-STRONG), in adolescents with pain from sickle cell disease.
- Trial name
- NCT06110754
- Testing
- I-STRONG for SCD
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- Emory University
Substance Use Disorders
Linking Individuals Needing Care for Substance Use Disorders to Peer Coaches
This is a 3-arm randomized controlled trial. Participants will be randomized via a maximally tolerated imbalance randomization procedure using NCI's Clinical Trial Randomization Tool with 1:1:1 allocation to each group: in-person…
- Trial name
- LINCS UP: RCT (NCT05847621)
- Testing
- Peer recovery coaching with linkage to recovery resources, Usual Care
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Emory University
Locally Advanced Unresectable Pancreatic Adenocarcinoma, Metastatic Pancreatic Adenocarcinoma
Telotristat Ethyl to Promote Weight Stability in Patients With Advanced Stage Pancreatic Cancer
This phase II trial studies how well telotristat ethyl works in promoting weight stability in patients with pancreatic adenocarcinoma that has come back and spread to other places in the body.
- Conditions
- Locally Advanced Unresectable Pancreatic Adenocarcinoma, Metastatic Pancreatic Adenocarcinoma, Recurrent Pancreatic Adenocarcinoma, Stage III Pancreatic Cancer AJCC v8
- Trial name
- NCT03910387
- Testing
- Gemcitabine, Nab-paclitaxel, Telotristat Ethyl
- Where
- 3 sites in United States
- Volunteers
- 23 people
- Sponsor
- Emory University
Lupus Erythematosus, Systemic
Women Empowered to Live With Lupus Study
The purpose of this research is to examine whether the Chronic Disease Self-management Program (CDSMP) would improve health outcomes and reduce health care use in African American women with systemic lupus erythematosus (SLE).
- Trial name
- WELL (NCT02988661)
- Testing
- Chronic Disease Self-management Program (CDSMP)
- Where
- United States
- Volunteers
- 699 people
- Sponsor
- Emory University
Type 1 Diabetes, Type 2 Diabetes
Automated Insulin Delivery for Inpatients With Dysglycemia
This randomized controlled trial will test the efficacy and safety of automated insulin delivery (AID) in hospitalized patients with diabetes (type 1 or type 2) requiring insulin therapy who are admitted to general…
- Trial name
- AIDING (NCT06418880)
- Testing
- AID system with Remote Real-Time CGM, Standard of Care Insulin Therapy + CGM
- Where
- 3 sites in United States
- Volunteers
- 130 people
- Sponsor
- Emory University
Idiopathic Nephrotic Syndrome
UrApp for Childhood Nephrotic Syndrome Management (Incident Cohort)
Idiopathic nephrotic syndrome is one of the most common chronic kidney diseases in children. Patients suffer from frequent disease relapses and complications.
- Trial name
- NCT04075656
- Testing
- Standard of Care, UrApp
- Where
- 3 sites in United States
- Volunteers
- 58 people
- Sponsor
- Emory University
Weight Change, Body
Healthy Homes/Healthy Families (HH/HF) Intervention in 2-1-1 Callers
This trial will evaluate a healthy eating and weight gain prevention intervention for delivery through calls to the 2-1-1 number.
- Trial name
- NCT04373434
- Testing
- Health Homes/Healthy Families (HH/HF) Intervention, Control
- Where
- United States
- Volunteers
- 512 people
- Sponsor
- Emory University