Clinical trials: sponsored by Federico II University
Cow's Milk Allergy
Epigenetic Effects Involved in Children With Cow's Milk Allergy (EPICMA)
Lactobacillus GG (LGG) is able to exert long lasting effects in children with atopic disorders. Nutramigen LGG accelerates tolerance acquisition in infants with cow's milk allergy.
- Trial name
- NCT02466035
- Testing
- Extensively hydrolyzed casein formula plus Lactobacillus rhamnosus GG
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Federico II University
NAFLD
Effects of Tomato Products in Children With NAFLD
CONTROLLED TRIAL ON THE EFFECT OF TOMATO PRODUCTS IN OBESE CHILDREN WITH NON ALCOHOLIC FATTY LIVER DISEASE Aim of the study To evaluate the effect of the addition of a daily dose of lycopene enriched tomato sauce on the progress…
- Trial name
- NCT03463967
- Testing
- Lycopene-enriched tomato juice, Energy-restricted diet
- Where
- Italy
- Volunteers
- 61 people
- Sponsor
- Federico II University
Malnutrition
Evaluation of the Efficacy of Nutritional Risk Screening Tests, NRS 2002 and SGA, to Identifying Malnourished Patients
In several hospital clinical trials, the nutritional intervention has been proven to be effective in preventing and/or reducing malnutrition.
- Trial name
- NCT03408067
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Federico II University
Type 2 Diabetes Mellitus, Celiac Disease
Fiber-enriched Buckwheat Pasta and Glucose Variability in Patients With Type 1 Diabetes and Celiac Disease
The intervention was preceded by a 1-week run-in period during which participants underwent continuous glucose monitoring (CGM) and filled in a 7-day dietary record to optimize basal infusion rate and insulin-to-glycemic load…
- Trial name
- NCT03380988
- Testing
- Acute test meal with fiber-enriched buckwheat pasta, Acute test meal with corn pasta
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Federico II University
Acute Diarrhea
Oral Administration of Tannins and Flavonoids in Children With Acute Diarrhea
A pilot, randomized, case-controlled trial was conducted in 60 children affected by AG (< 7 days) with mild-moderate dehydration, according to WHO recommendations, from1 year to 17 years old.
- Trial name
- NCT03356327
- Testing
- Actitan F, Standard Oral Rehydration
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federico II University
Renal Insufficiency, Chronic, Dialysis
Egg White for Phosphorus Control in Haemodialysis Patients
To evaluate the effect on phosphatemia in hemodialysis patients of replacing the meat or fish included in two meals a week with an amount of egg white containing the same quantity of proteins.
- Conditions
- Renal Insufficiency, Chronic, Dialysis, Hyperphosphatemia
- Trial name
- UAUDIPE (NCT03236701)
- Testing
- Egg White replacement
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Federico II University
Hyperglycemia
Metabolic Effects of High-amylose Wheat-based Rusks.
Amylose-amylopectin ratio may influence the rate of starch digestion. This randomized controlled study evaluated the postprandial metabolic effects of amylose-rich- wheat- based rusks in overweight subjects.
- Trial name
- NCT02702934
- Testing
- Test meal
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Federico II University
Healthy Volunteers
Metabolic Response to the Acute Consumption of Fiber-enriched Pasta
Cardio-metabolic diseases are a leading cause of mortality worldwide. Over the years, therefore, there have been considerable efforts to identify strategies for prevention and management of risk factors.
- Trial name
- PROPASTA (NCT02842606)
- Testing
- Test meal
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Federico II University
Chronic Heart Failure
Interval Training and Hormones in Chronic Heart Failure
The investigators aim at investigating whether 24-week high intensity interval training might exert beneficial effects by modulating neurohormonal axis in patients with chronic heart failure (CHF).
- Trial name
- NCT02322034
- Testing
- Interval Training
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Federico II University
Cow's Milk Allergy, Functional Gastrointestinal Disorders
Cow's Milk Allergy and Functional Gastrointestinal Disorders
Cow's milk allergy (CMA) is the most common food allergy in early childhood, with an estimated incidence ranging between 2% and 3% in infants and marginally lower in older children.
- Trial name
- NCT01901380
- Testing
- Extensively hydrolyzed casein formula + LGG
- Where
- Italy
- Volunteers
- 220 people
- Sponsor
- Federico II University
Celiac Disease
INF-α Innate Immune Response to Gliadin
Background \& Aims The enteropathy in Celiac Disease (CD) is due the adaptive and to the innate immune response to gliadin peptides.
- Trial name
- NCT03221647
- Testing
- Intestinal biopsies
- Where
- Italy
- Volunteers
- 53 people
- Sponsor
- Federico II University
Mediterranean Diet, Trimethylamine N-oxide
Mediterranean Diet, Trimethylamine N-oxide (TMAO) and Anti-oxidants in Healthy Adults
Trimethylamine N-oxide (TMAO) is a small organic compound naturally present in fish and seefood or generated by the bacterial breakdown of dietary phosphatidylcholine and carnitine-containing foods within the human gut…
- Conditions
- Mediterranean Diet, Trimethylamine N-oxide, Cardiovascular Risk Factor
- Trial name
- TMED (NCT03060811)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Federico II University
Crohn Disease
Surgical Prevention of Anastomotic Recurrence by Excluding Mesentery in Crohn's Disease
Kono and collegues have described a new anastomotic technique to restore bowel contintuity after ileocecal resection for Crohn's disease (CD).
- Trial name
- SuPREMeCD (NCT02631967)
- Testing
- Kono anastomosis, Stapled side-to-side anastomosis
- Where
- Italy
- Volunteers
- 132 people
- Sponsor
- Federico II University
Airway Management
Videolaryngoscopes for Tracheal Intubation
The primary end point of this study is the feasibility of intubation. The secondary end-points are the success to intubate in the first attempt, the intubation time, the Cormack and Lehane score view, the comparison of the…
- Trial name
- NCT02897518
- Testing
- Imago V-Balde, Glidescope
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Federico II University
Heart Failure, Hormone Deficiencies
Hormone Deficiency in Heart Failure With Preserved Ejection Fraction
The objective of this study is to describe the prevalence of Multiple Hormone Deficiencies in Heart Failure with preserved Ejection Fraction.
- Trial name
- MHDS in HFpEF (NCT02976350)
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- Federico II University
Single Tooth Lost
Posterior CAD/CAM Cobalt-chromium Alloy Single Crowns: 4-year Prospective Clinical Study
Objectives - To evaluate the 4-year clinical outcomes of ceramic veneered Computer Aided Design/Computer Aided Manufacturing (CAD/CAM) Co-Cr single crowns supported by natural teeth in posterior regions.
- Trial name
- NCT02956174
- Testing
- Co-Cr single crown, Periodontal parameters
- Volunteers
- 89 people
- Sponsor
- Federico II University
Infant Colics
Efficacy of a Partially Hydrolyzed Formula, Containing Lactobacillus Reuteri, for Infant Colic
Infant colic (IC) is responsible of 25% of pediatric consultation in the first 3-4 months of life affecting from 5% to 30% of infants between 2 weeks and 3 months of life (3, 4).
- Trial name
- NCT02813772
- Testing
- Milk formula NAN Sensitive, Nestle, Milk formula Optipro, Nestle
- Where
- Italy
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Federico II University
Healthy
Bioavailability of the Polyphenols Contained in a Red Grape Extract-based Drink and Their Metabolic Effects
Randomized placebo-controlled crossover study during which participants undergo two different experimental days. The participants consume a red grape based- drink (polyphenols: 300 mg/100 ml and sugar: 9.8g/100 ml) or a placebo…
- Trial name
- BIOP (NCT02865278)
- Testing
- Standard meal
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Federico II University
Multiple Sclerosis
The Effects of Focal Vibration on Spasticity in Multiple Sclerosis Patients
This trial consists of application of little devices (named Equistasi®) generating focal vibrations to treat spasticity in neurological patients, affected by multiple sclerosis.
- Trial name
- NCT02848898
- Testing
- Equistasi
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Federico II University
Infantile Colics
Efficacy of Matricariae Chamomilla L., Melissa Officinalis L. and Tyndallized Lactobacillus Acidophilus (H122) for Infantile Colics
A multicenter prospective, randomized comparative study will be conducted in infants with colic, according to Rome III criteria. Enrolled infants will be assigned at random to receive Chamomilla L., Melissa Officinalis L.
- Trial name
- NCT02708238
- Testing
- Standardized extract of Chamomilla L., Melissa Officinalis L. and tyndallized L. Acidophilus (H122), Lactobacillus reuteri DSM 17938 (108 CFU), Simethicone
- Volunteers
- 180 people
- Sponsor
- Federico II University