Clinical trials: sponsored by Federico II University
Mediterranean Diet, Phase Angle
Adherence to Mediterranean Diet and Phase Angle
In this cross-sectional observational study the investigators evaluated the association between the adherence to the MD and PhA in a sample of adult population, stratified according to categories of sex, age, and BMI.
- Trial name
- NCT02840968
- Volunteers
- 1,464 people, healthy volunteers welcome
- Sponsor
- Federico II University
Mediterranean Diet, Nutrition
Adherence to the Mediterranean Diet and Circulating Levels of Sirtuin 4 in Obese Subjects
The Mediterranean diet (MD), a healthy dietary pattern based on some common dietary characteristics in Mediterranean countries, is associated with high antioxidant capacity linked to the low saturated fat intake that might…
- Conditions
- Mediterranean Diet, Nutrition, Sirtuin 4, Obesity
- Trial name
- NCT02840981
- Volunteers
- 43 people
- Sponsor
- Federico II University
Cow's Milk Allergy
Epigenetic Features of FoxP3 in Children With Cow's Milk Allergy
Epigenetic mechanisms have been implicated in the pathogenesis of food allergy. The investigators previously demonstrated that tolerance acquisition in children with Immunoglobulin E- (IgE) mediated cow's milk allergy (CMA) is…
- Trial name
- NCT02779881
- Testing
- Extensively hydrolyzed casein formula plus LGG
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Federico II University
Medullary Thyroid Cancer
SOM230 Alone or in Combination With RAD001 in Patients With Medullary Thyroid Cancer
A mono centre study to evaluate the efficacy of SOM230 in patients with progressive metastatic or postoperative persistent medullary thyroid cancer.
- Trial name
- NCT01625520
- Testing
- SOM230 alone or in combination with RAD001.
- Where
- Italy
- Volunteers
- 19 people
- Sponsor
- Federico II University
Preterm Birth
Cervical Cerclage for Preventing Spontaneous Preterm Birth in Singleton Pregnancies Without Prior Spontaneous Preterm Birth and With Short Transvaginal Ultrasound Cervical Length
Spontaneous preterm birth (SPTB) remains the number one cause of perinatal mortality in many countries, including the United States.
- Trial name
- NCT02746900
- Testing
- Cervical cerclage
- Where
- Italy
- Volunteers
- 587 people
- Sponsor
- Federico II University
Insulin Resistance, Obesity
The Effects of Butyrate on Children With Obesity
Butyrate is a short chain fatty acid (SCFA) produced by bacterial fermentation of undigested starch in the gut. Butyrate carries out different effects at intestinal and extraintestinal level, including: immune regulation with…
- Trial name
- NCT02721953
- Testing
- Butyrate
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Federico II University
Preterm Birth
Cerclage for Singletons With Short Cervix Without Prior Preterm Birth
Preterm birth remains the most common cause of perinatal morbidity and mortality. A short cervi- cal length on transvaginal ultrasonography has been shown to be one of the best predictors of preterm birth.
- Trial name
- NCT02716922
- Testing
- Cervical cerclage
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Federico II University
Glucose and Lipid Metabolism, Incretin Hormones Plasma Levels
Effects of Aleurone-enriched Products on Cardiovascular Risk Factors
Very few studies have evaluated the effect of aleurone-enriched grains on cardiovascular risk factors. Price et al.(2010) have shown that 4-week supplementation of aleurone-enriched products (27 g/day of aleurone) increased…
- Conditions
- Glucose and Lipid Metabolism, Incretin Hormones Plasma Levels, Inflammation, Oxidative Stress and Endothelial Function
- Trial name
- NCT02150356
- Testing
- Aleurone, Control
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- Federico II University
Metabolic Syndrome
The Role of a Combination of Nutraceuticals in the Control of Cardiovascular Risk
Cardiovascular risk has been shown to increase with increasing blood pressure values. As a consequence, it results mandatory to achieve lower blood pressure goals in all hypertensive patients, taking into account that all drugs…
- Trial name
- ARMOPREVCVR (NCT01293162)
- Testing
- Armolipid Prev
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Federico II University
Ventricular and Atrial Extrasytoles
Role of a Combination of Nutraceuticals (Ritmonutra) on Benign Supraventricular and Ventricular Arrhythmias
Study on the role of a combination of nutraceuticals (Ritmonutra) with an effect on benign supraventricular and ventricular extrasystoles in subjects free of a specific organic heart disease.
- Trial name
- NCT01647984
- Testing
- Ritmonutra
- Where
- Italy
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Federico II University
Chronic Sacrococcygeal Pilonidal Sinus
Video Assisted Ablation of Pilonidal Sinus Versus Conventional Treatment
Video assisted ablation of pilonidal sinus (VAAPS) is a new endoscopic minimally invasive treatment. In an attempt to validate the effectiveness of the VAAPS, the investigators have designed a comparative study between the…
- Trial name
- NCT02222298
- Testing
- Video assisted ablation of pilonidal sinus, Bascom Cleft lift procedure
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Federico II University
Obesity, Overweight
Metabolic Effect of New Foods Through Gut-brain Axis
A diet high in easily obtained energy-dense foods leads to the problems of overweight and obesity common in the developed world. Foods enriched with fiber or bitter compounds may increase satiety and decrease energy intake.
- Trial name
- CHECKMATE (NCT01851304)
- Testing
- Satiety of breads, Satiety of puddings
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Federico II University
Irritable Bowel Syndrome, Dyspepsia Chronic
Bifidobacteria In Children With Abdominal Pain-Associated Functional Gastrointestinal Disorders
Abdominal pain (AP)-associated functional gastrointestinal disorders (FGIDs), particularly Irritable Bowel Syndrome (IBS) and Functional Dyspepsia (FD), are common in pediatrics, and no safe and effective treatment is available.
- Trial name
- NCT02566876
- Testing
- Mixture of three Bifidobacteria
- Where
- Italy
- Volunteers
- 73 people
- Sponsor
- Federico II University
Cystic Fibrosis
Probiotics in Cystic Fibrosis
Cystic fibrosis (CF) is a complex systemic disease that mainly involves the respiratory and gastrointestinal (GI) tracts. The polymicrobial community composition of respiratory and GI tracts is influenced by both genetic and…
- Trial name
- NCT01956916
- Testing
- Lactobacillus rhamnosus GG
- Where
- 5 sites in Italy
- Volunteers
- 110 people
- Sponsor
- Federico II University
Nosocomial Infection
Administration of a Lactobacillus GG and Vitamins Containing Mixture is Effective in Preventing Nosocomial Infection in Children
Nosocomial infections are infections that occur from the time of 'entry in the hospital up to 48h after discharge. In most developed countries, the incidence of nosocomial infections in children is between 5% and 44% with the…
- Trial name
- NCT02558192
- Testing
- Lactobacillus Rhamnosus GG
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Federico II University
Friedreich Ataxia
Efficacy Study of Epoetin Alfa in Friedreich Ataxia
Friedreich's ataxia (FRDA) is a rare genetic disorder characterised by severe neurological disability and cardiomyopathy. Friedreich's ataxia is the consequence of frataxin deficiency.
- Trial name
- FRIEMAX (NCT01493973)
- Testing
- Epoetin alfa
- Where
- 3 sites in Italy
- Volunteers
- 56 people
- Sponsor
- Federico II University
Acute Gastroenteritis, Upper Respiratory Tract Infections
Fermented Milk on the Appearance of Common Winter Infectious Diseases
Respiratory and gastrointestinal infections are common in children under the age of 4 years, especially after the start of schooling.
- Trial name
- NCT02367612
- Testing
- Fermented milk
- Where
- 3 sites in Italy
- Volunteers
- 140 people
- Sponsor
- Federico II University
Gastrointestinal Infections, Respiratory Infections
Fermented Milk and Fermented Rice on the Appearance of Respiratory and Gastrointestinal Symptoms
The respiratory and gastrointestinal infections are a very common problem with high morbidity in children. These conditions were due, in general, immaturity and all "inexperience" of the immune system, as well as to the…
- Trial name
- NCT01909128
- Testing
- fermented milk, fermented rice
- Where
- Italy
- Volunteers
- 405 people
- Sponsor
- Federico II University
Cow's Milk Allergy
Effect of Therapy With Aminoacid Based Formula Versus Hydrolyzed Whey Proteins in Children With Cow's Milk Allergy
Cow's milk allergy is an immunologically mediated adverse reaction to milk proteins. In industrialized countries there is an incidence of 2-3% in children younger than 2 years.
- Trial name
- NCT02379598
- Testing
- Aminoacid based formula, Hydrolyzed whey formula
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Federico II University
Diabetes Mellitus, Type 1
Postprandial Blood Glucose Control and Gastric Emptying in Type 1 Diabetes: Pathogenetic Factors and Therapeutic Options
This study evaluates the prevalence of gastric emptying (GE) in type 1 diabetic patients (DM1) free of chronic complications in comparison with a group of healthy control subjects.
- Trial name
- NCT02365740
- Testing
- gastric emptying test, gut hormones determination, Continuous Glucose Monitoring
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federico II University