Clinical trials: sponsored by Fujian Medical University
Advanced Hepatocellular Carcinoma
A Study of TAE+HAIC Combined With Camrelizumab and Apatinib in the Treatment of Advanced Hepatocellular Carcinoma
To evaluate the efficacy and safety of TAE+HAIC combined with camrelizumab and apatinib in the treatment of advanced liver cancer with high tumor load
- Trial name
- NCT06363825
- Testing
- camrelizumab
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Fujian Medical University
Gastric Cancer
Systemic Oxidative Stress Score as a Predictor of Gastric Cancer Survival and Recurrence Risk
The Systemic Oxidative Stress Score (SOSS) , a comprehensive score reflecting the oxidative stress conditions in the microenvironment, can independently and effectively predict tumor burden and long-term prognosis in GC patients.
- Trial name
- NCT06337279
- Where
- China
- Volunteers
- 3,820 people
- Sponsor
- Fujian Medical University
Gastric Cancer
A Novel Online Calculator to Predict Long-term Survival and Recurrence Risk of Patients With Gastric Adenocarcinoma
This study aimed to develop a novel Prognostic Oxidative Stress-Immune-Inflammatory Score (POSII Score) and introduce an innovative online calculator designed to predict long-term survival and assess the recurrence risk of…
- Trial name
- NCT06337266
- Where
- China
- Volunteers
- 3,622 people
- Sponsor
- Fujian Medical University
Diffuse Large B-cell Lymphoma
R-DA-EDOCH Versus R-CEOP90, With/Without Upfront Auto-HSCT in Young Patients With High-risk DLBCL
Patients initially are randomized into 2 arms: Arm I: R-DA-EPOCH; Arm II: R-CEOP90; Patients who achieved complete remission (CR) or partial remission (PR) after 6 cycles of R-DA-EPOCH (Arm I) or R-CEOP90 (Arm II), continue to…
- Trial name
- NCT03213977
- Testing
- R-DA-EPOCH, R-CEOP90
- Where
- China
- Volunteers
- 475 people
- Sponsor
- Fujian Medical University
Breast Cancer, COVID-19
Timing of Surgery and the Evolution of Postoperative Outcomes in Breast Cancer Patients Undergoing Surgical Intervention Following Recovery From SARS-CoV-2 Infection
Perioperative SARS-CoV-2 infection significantly increases the risk of postoperative complications and mortality, while also exerting long-lasting impacts on multiple organs and systems.
- Conditions
- Breast Cancer, COVID-19, Postoperative Complications
- Trial name
- NCT06319209
- Testing
- Preoperative resolved COVID-19
- Where
- China
- Volunteers
- 392 people
- Sponsor
- Fujian Medical University Union Hospital
Pancreatic Neoplasms
Single-cell Sequencing Analysis of Resectable/Borderline Resectable Pancreatic Cancer Patients
Preoperative neoadjuvant chemotherapy is widely used in treating patients with borderline resectable pancreatic cancer (BRPC). However, there are limitations in this field.
- Trial name
- NCT06310902
- Testing
- Single-cell Sequencing Analysis
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Fujian Medical University Union Hospital
Pulmonary Infection, Pneumonia, Bacterial
Eravacycline Combination Therapy for MRAB
The goal of this observational study is to learn about the eravacycline combination therapy in multidrug-resistant acinetobacter gaumannii pneumonia. The main question is to evaluate the the effectiveness and safety.
- Conditions
- Pulmonary Infection, Pneumonia, Bacterial, Acinetobacter Baumannii
- Trial name
- NCT06282835
- Testing
- Eravacycline Injection
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Fujian Medical University Union Hospital
Tumor Positron-Emission Tomography
A Head-to-head Comparison of [68Ga]Ga-FAPI and [68Ga]Ga-TATE PET/CT in Patients With Nasopharyngeal Carcinoma: a Single-center, Prospective Study
Both fibroblast activation protein (FAP)-targeted imaging and somatostatin receptors (SSTR)-targeted imaging were the promising imaging modalities for the diagnosis of primary and metastatic nasopharyngeal carcinoma (NPC).
- Trial name
- NCT05990998
- Testing
- 68Ga-DOTATATE and 68Ga-FAPI
- Where
- China
- Volunteers
- 38 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Overall Response Rate
A Study on the Safety and Efficacy of the Combination of Candenizumab, Lenvatinib, and SOX Regimen in the Treatment of HER2 Negative Advanced Gastric or Gastroesophageal Junction Adenocarcinoma Patients
Evaluate the objective response rate (ORR) of the combination of candenizumab, lenvatinib, and SOX regimen for the treatment of HER2 negative advanced gastric or gastroesophageal junction adenocarcinoma patients
- Trial name
- NCT06277024
- Testing
- Combination of Cardonizumab with Lenvatinib and SOX regimen
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Fujian Medical University
Locally Advanced Gastric Cancer
Effect of Adjuvant Chemotherapy Cycles on Patients With Node-negative Gastric Cancer Following Neoadjuvant Chemotherapy
To explore the effect of adjuvant chemotherapy cycles on the prognosis of this specific patient with lymph node-negative gastric cancer following neoadjuvant chemotherapy.
- Trial name
- NCT06277453
- Testing
- surgery
- Where
- China
- Volunteers
- 219 people
- Sponsor
- Fujian Medical University
Locally Advanced Gastric Cancer
The Safety and Efficacy of Neoadjuvant Immunochemotherapy Followed by Laparoscopic Gastrectomy for Gastric Cancer
To evaluate the safety and effectiveness of laparoscopic gastrectomy (LG) following neoadjuvant immunochemotherapy (nICT)
- Trial name
- NCT06235164
- Testing
- immune checkpoint inhibitors: sintilimab, nivolumab, and camrelizumab
- Where
- China
- Volunteers
- 585 people
- Sponsor
- Fujian Medical University
Gastric Cancer, Machine Learning
Predict 5-Year Survival in Elderly Gastric Cancer
In this study, elderly patients with gastric cancer who underwent radical gastrectomy in Union Hospital Affiliated to Fujian Medical University from 2012 to 2018 were included as a derived cohort, and the training set and…
- Trial name
- NCT06208046
- Where
- China
- Volunteers
- 2,187 people
- Sponsor
- Fujian Medical University
Orthostatic Hypotension, Alzheimer Disease
Efficacy, Safety and Response Predictors of Adjuvant Astragalus for Cognition in Orthostatic Hypotension
Background: This pragmatic clinical trial aims to determine the efficacy and safety of add-on Astragalus for cognition and non- cognition in patients with of mild to moderate Alzheimer's disease complicated with orthostatic…
- Trial name
- NCT05647473
- Testing
- Routine treatment, add-on low dose Astragalus, add-on high dose Astragalus
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Fujian Medical University Union Hospital
Breast Cancer, Sentinel Lymph Node
Impact of a Predictive Model on Sentinel Lymph Node Biopsy in Initially Lymph Node-positive, HER2-positive Breast Cancer
The aim of the study was to develop and validate a nomogram to assess axillary pathological complete response (pCR) in patients with initially lymph node-positive, human epidermal growth factor receptor 2 (HER2)-positive breast…
- Trial name
- NCT06149377
- Testing
- Test cohort
- Where
- China
- Volunteers
- 716 people
- Sponsor
- Fujian Medical University Union Hospital
Esophageal Squamous Cell Carcinoma Thoracic Stage II, Esophageal Squamous Cell Carcinoma Thoracic Stage III
Postoperative Immune Maintenance Therapy for Esophageal Squamous Cell Carcinoma After Radical Resection
Esophageal cancer (EC) is one of the most common malignant tumors of the digestive tract in human beings. Most cases of EC are initially diagnosed in an advanced stage of the disease.
- Conditions
- Esophageal Squamous Cell Carcinoma Thoracic Stage II, Esophageal Squamous Cell Carcinoma Thoracic Stage III, Esophageal Squamous Cell Carcinoma Thoracic Stage IV
- Trial name
- NCT06161909
- Testing
- sintilimab
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Fujian Medical University Union Hospital
Lung Cancer Stage I, Quality of Life
Postoperative Chronic Operation-related Symptoms After Minimally Invasive Lung Surgery
Lung cancer has been the most commonly diagnosed cancer globally over the past few decades. Histologically, adenocarcinoma in situ (AIS) and minimally invasive adenocarcinoma (MIA) are defined as cancers with no or limited tissue…
- Trial name
- NCT06016881
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Fujian Medical University Union Hospital
General Anesthesia Induction for Elective Surgery
Carotid Artery Corrected Flow Time as a Predictor of Hypotension After Induction of General Anesthesia in Elderly Patients
The number of elderly patients undergoing elective surgery has been growing in recent years. Elderly patients often have a variety of underlying diseases, including hypertension, coronary heart disease, diabetes…
- Trial name
- NCT05628051
- Testing
- ultrasonographic measurement of carotid artery corrected flow time (FTc)
- Where
- China
- Volunteers
- 177 people
- Sponsor
- Fujian Medical University Union Hospital
Hepatocellular Carcinoma Resectable
A Clinical Study of Tislelizumab Combined With TACE and Lenvatinib in the Neoadjuvant Treatment of Resectable HCC
In order to improve the R0 resection rate, reduce distant metastasis, and lower postoperative recurrence, there is a growing exploration of surgical treatments for hepatocellular carcinoma (HCC), including preoperative…
- Trial name
- NCT06003673
- Testing
- neoadjuvant therapy
- Where
- China
- Volunteers
- 20 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Indocyanine Green, Gastric Cancer
Randomized Controlled Trial on Effect of Lymph Node Mapping by Indocyanine Green Via Submucosal or Subserosal Injection
The purpose of this study was to evaluate whether submucosal or subserous injection of indocyanine green during laparoscopic lymphadenectomy for patients with gastric cancer was different.
- Conditions
- Indocyanine Green, Gastric Cancer, Injection Site
- Trial name
- NCT04219332
- Testing
- Subserosa injection of indocyanine green, submucosal injection of indocyanine green
- Where
- China
- Volunteers
- 266 people
- Sponsor
- Fujian Medical University
Tooth Bleaching
The Effectiveness of At-home , In-office and Combined Dental Bleaching System ：A Randomized Controlled Clinical Trial
This randomized controlled clinical trial aimed to investigate the effectiveness of at-home , in-office and combined dental bleaching system.
- Trial name
- NCT05021965
- Testing
- different combined of tooth bleaching procedure
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University