Clinical trials: sponsored by Fujian Medical University
Prostate Cancer (Adenocarcinoma)
68Ga-PSMA-11 PET Imaging for Diagnosing Prostate Cancer, a Head-to-head Comparison With mpMRI
68Ga-PSMA-11 is a widely used radiotracer targeting PSMA. In this study, we investigated the diagnostic efficacy of 68Ga-PSMA-11 PET imaging (PET/CT or PET/MRI) in patients with newly diagnosed, treatment-naive prostate cancer…
- Trial name
- NCT07209878
- Testing
- 68Ga-PSMA-11
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Prosthetic Joint Infection, Unicompartmental Knee Arthroplasty
Metal Artifact Reduction Sequence MRI for Surgical Decision-Making in Infected Unicompartmental Knee Arthroplasty
A single-center retrospective cohort study was conducted in the Department of Orthopedics of Fujian Medical University Affiliated First Hospital.
- Trial name
- NCT07208968
- Where
- China
- Volunteers
- 28 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
NAFLD, Diabete Type 2
The Improvement Effect of Henggliejin on Fatty Liver in Type 2 Diabetes Patients With Nonalcoholic Fatty Liver:
To evaluate the effect and safety of Henggliejin on fatty liver in type 2 diabetes patients with nonalcoholic fatty liver disease
- Trial name
- NCT07198516
- Testing
- Addition of Hengge Liejing treatment for 48 weeks
- Volunteers
- 149 people
- Sponsor
- Fujian Medical University Union Hospital
Chronic Cough, Video-assisted Thoracoscopic Surgery (VATS)
A Prospective, Randomized, Double-blind Study on the Effects of Different Anesthesia Strategies on Postoperative Cough in Patients Undergoing Video-assisted Thoracoscopic Surgery.
This study aims to systematically evaluate the effects of different anesthesia methods on postoperative chronic cough in lung cancer patients undergoing video-assisted thoracoscopic lung resection (VATS), and to clarify the…
- Trial name
- Chronic cough (NCT07190664)
- Testing
- Patients were randomly grouped
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University Union Hospital
Renal Cell Carcinoma (RCC)
CT-based Radiomics for Prediction of MIT Family Translocation Kidney Cancer: a Multicenter, Retrospective Clinical Study
This project intends to construct a multicenter retrospective study, retrospectively collect clinical, imaging, pathological and prognostic data of patients, establish a complete data management system, establish a prediction…
- Trial name
- NCT07181954
- Volunteers
- 746 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Renal Carcinoma, Serology
Serological Autoantibodies in Early Kidney Cancer Diagnosis and Prognosis: A Multicenter Study
This project aims to construct a multicenter retrospective study by retrospectively collecting clinical, serological, and pathological data from patients.
- Conditions
- Renal Carcinoma, Serology, Autoantibody
- Trial name
- NCT06917560
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Fujian Medical University
AML, Adult
Leptin: A Marker for AML Chemo-Sensitivity
Acute Myeloid Leukemia (AML) is a malignant clonal disorder of hematopoietic stem/progenitor cells, with a five-year survival rate of approximately 30%. Chemotherapy resistance and relapse remain major challenges.
- Trial name
- NCT07163728
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Fujian Medical University Union Hospital
Intertrochanteric Fractures, Internal Fixation Failure
Controlling Nutritional Status as a Superior Predictor of Fixation Failure in Intertrochanteric Fractures: Development and Validation of a Multicentre Nomogram
A multicentre retrospective cohort study was conducted within the Department of Orthopaedics at the First Affiliated Hospital of Fujian Medical University.
- Conditions
- Intertrochanteric Fractures, Internal Fixation Failure, CONUT Score, Nomogram Model
- Trial name
- NCT07159945
- Where
- China
- Volunteers
- 1,296 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Renal Cell Carcinoma (RCC)
Computed Tomography Radiomics-Derived Nomogram for Predicting Early Renal Function Decline After Partial Nephrectomy in Renal Cell Carcinoma: A Multicenter Development/Validation Study
The goal of this observational study is to explore the relationship between CT-based radiomics and postoperative renal function changes in patients with localized renal cell carcinoma (RCC) undergoing partial nephrectomy (PN).
- Trial name
- NCT07117786
- Testing
- CT Contrast, Computed Tomography
- Volunteers
- 1,437 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Stroke, Microbial Disease
Estimate the Relationship Between Oral Microbiota and Stroke
Oral bacteria constitute the second largest population of the human microbiome. Recent studies have identified their role in the development of systemic diseases, such as cardiovascular and cerebrovascular diseases.
- Trial name
- NCT06479915
- Where
- 2 sites in China
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
Temporomandibular Disorder (TMD)
The Effectiveness of Different Therapeutic Jaw Position Determining Methods in Repositioning Splint Therapy for Temporomandibular Joint Disk Displacement Without Reduction：A Randomized Controlled Clinical Trial
The goal of this clinical trial is to learn if different therapeutic jaw position determining methods influence the efficacy of repositioning splint therapy for temporomandibular joint disk displacement without reduction.
- Trial name
- NCT07090772
- Testing
- Repositioning splint therapy with jaw position determined by mechanical articulator, Repositioning splint therapy with jaw position determined by ai-assisted virtual articulator, Repositioning splint therapy with jaw position determined by ai-assisted virtual patient
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Fujian Medical University
Carbapenem-Resistant Enterobacteriaceae Infection, Pneumonia - Bacterial
Different Methods of Aerosolized Polymyxin B Inhalation for Treating Carbapenem-Resistant Gram-Negative Bacterial Pneumonia.
Study Design: A randomized, open-label, parallel-group clinical trial comparing the efficacy and safety of jet nebulization versus vibrating mesh nebulization of sulfate polymyxin B in mechanically ventilated patients with…
- Trial name
- NCT07086391
- Testing
- Polymyxin B Sulfate 25mg Jet Nebulization / Vibrating Mesh Nebulization
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Fujian Medical University Union Hospital
Older Adults
Social Participation Program for Older Adults in Nursing Homes
The goal of this clinical trial is to learn whether a multi-level social participation program can help improve social engagement and slow down cognitive decline in older adults living in nursing homes.
- Trial name
- NCT07079124
- Testing
- Multi-level Social Participation Intervention, Health Education
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
Thyroid Surgery
Quantitative Intra-operative Assessment of Parathyroid Perfusion Using Indocyanine Green (ICG) Fluorescence Imaging
This single-center, prospective, three-phase observational cohort quantifies the relationship between indocyanine green (ICG) fluorescence and early parathyroid function.
- Trial name
- NCT07010341
- Testing
- ntra-operative Indocyanine Green (ICG) Fluorescence Quantification
- Where
- 2 sites in China
- Volunteers
- 210 people
- Sponsor
- Fujian Medical University
Prostate CA
Research on the Application of 68Ga-PSMA-CYC PET Imaging in the Diagnosis, Staging, and Restaging of Prostate Cancer
68Ga-PSMA-CYC is a novel radiotracer targeting PSMA. In this study, we investigated the safety, biodistribution, radiation dosimetry of 68Ga-PSMA-CYC PET/CT in patients with prostate cancer, and performed a head-to-head…
- Trial name
- NCT07056790
- Testing
- 68Ga-PSMA-CYC, CYC
- Where
- China
- Volunteers
- 40 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Thyroid Neoplasms, Carcinoma, Papillary
Hybrid Endoscopic Hemithyroidectomy and Targeted Ablation for Bilateral Papillary Thyroid Carcinoma
This study evaluates a thyroid-function-preserving alternative to routine total thyroidectomy for bilateral papillary thyroid carcinoma (PTC).
- Trial name
- NCT07033572
- Testing
- Endoscopic Hemithyroidectomy with Central-Neck Dissection, Ultrasound-Guided Radiofrequency Ablation of Contralateral Nodule
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Fujian Medical University
Hyperparathyroidism, Primary, Parathyroid Neoplasms
WHITE CAP: Intra-operative Parathyroid Tissue Sensor (PTS)-Guided Assessment of Parathyroid Viability and Surgical Decision-Making
Primary hyperparathyroidism is usually cured by removing the single over-active parathyroid adenoma. During surgery, however, surgeons often see a thin rim of normal parathyroid tissue that still "glows" under a near-infrared…
- Conditions
- Hyperparathyroidism, Primary, Parathyroid Neoplasms, Parathyroid Adenoma, Hypocalcemia
- Trial name
- WHITE CAP-PTS (NCT07043010)
- Testing
- Near-Infrared Parathyroid Tissue Sensor Imaging (PTS), Rim-Preservation Technique, En-bloc Resection Technique
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Fujian Medical University
Papillary Thyroid Carcinoma, Thyroid Neoplasms
RET-US Study - Ultrasound-Based Prediction of RET Alterations and Lateral-Neck Metastasis in Thyroid Cancer
Why is this study being done? RET gene alterations occur in only 5-10 % of papillary thyroid cancers, but they can change how surgeons treat the disease.
- Conditions
- Papillary Thyroid Carcinoma, Thyroid Neoplasms, RET Proto-Oncogene Mutation, Lymphatic Metastasis
- Trial name
- RET-US (NCT07042984)
- Testing
- AI-Ultrasound RET Prediction
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Fujian Medical University
Postoperative Delirium
Effects of Different Preoperative Oral Rehydration Protocols in Undergoing Thoracoscopic Radical Lung Cancer Surgery
This study aims to compare the new preoperative oral rehydration protocol (administering 50-100 mL of clear fluids or carbohydrate-rich beverages orally every hour until the patient arrives at the operating room) with the…
- Trial name
- NCT07042503
- Volunteers
- 420 people
- Sponsor
- Fujian Medical University Union Hospital
Vocal Cord Paralysis, Bilateral, Airway Obstruction, Postoperative
Peri-operative BiPAP to Prevent Tracheostomy in High-Risk Bilateral Vocal-Cord Paralysis (BVCP)
Why: After thyroid or neck surgery, some patients can lose movement of both vocal cords (bilateral vocal-cord paralysis, BVCP). This can make breathing difficult and often leads to an emergency or preventive tracheostomy…
- Conditions
- Vocal Cord Paralysis, Bilateral, Airway Obstruction, Postoperative, Thyroid Neoplasms, Sleep Apnea, Obstructive
- Trial name
- BVCP-BiPAP (NCT07042971)
- Testing
- Pre-operative BiPAP Training, Post-extubation BiPAP Support, Standard Peri-operative Care
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Fujian Medical University