Clinical trials: sponsored by Göteborg University
Critical Illness, Ethics
Life Sustaining Treatments in Critically Ill Children
Summary of the Research on Withdrawing and Withholding Life-Sustaining Treatment for Critically Ill Children Background Medical treatments require regular evaluation to ensure they align with the patient's best interests…
- Conditions
- Critical Illness, Ethics, End of Life Care
- Trial name
- LST-Ped-Int (NCT07401420)
- Testing
- There is no intervention
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Göteborg University
Pediatric Disorder, Critical Illness
Attitudes to Decisions to Withdraw or Withhold Life-sustaining Treatments in Critically Ill Children
The aim of this study is to investigate attitudes on decisions to withdraw or withhold life-sustaining treatments in critically ill children in Swedish intensive care units.
- Conditions
- Pediatric Disorder, Critical Illness, Ethics, Narrative
- Trial name
- LSTPedSurvey (NCT06281743)
- Testing
- Survey
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Göteborg University
Depression Mild, Depression Moderate
iCBT for Seniors With Depression in Primary Care
This clinical trial aims to evaluate the potential benefits of internet cognitive behavioural therapy (iCBT) for elderly patients with mild/moderate depression and compare its effectiveness with the current treatment as usual…
- Trial name
- NCT06537869
- Testing
- iCBT for depression
- Where
- Sweden
- Volunteers
- 390 people
- Sponsor
- Göteborg University
Asthma in Children, Transplantation
Digital Delivery of Person-centered Transitional Care
Advances in medical care have extended the life expectancy of individuals with congenital and pediatric-onset diseases, leading to an increased need for effective transition programs as these individuals move from pediatric to…
- Trial name
- DigiStep (NCT06823622)
- Testing
- Stepstones transition program
- Where
- 2 sites in Sweden
- Volunteers
- 100 people
- Sponsor
- Göteborg University
Bipolar Depression
OSU6162 in Bipolar Depression (OBID)
An explorative, open label, single armed, flexible dose, single center, phase IIa study of 8 weeks, initiated in subjects with bipolar depression. The study will consist of 9 visits and 1 safety visit.
- Trial name
- OBID (NCT05296356)
- Testing
- OSU6162
- Where
- Sweden
- Volunteers
- 22 people
- Sponsor
- Göteborg University
Depression, Depressive Disorder, Treatment-Resistant
OSU6162 as add-on in SSRI/SNRI-resistant Depression
This is a randomised, placebo-controlled, parallel-group trial comparing OSU6162 at flexible dosage with placebo as add-on to treatment with an SSRI/SNRI in patients with depression that have not responded to treatment with an…
- Conditions
- Depression, Depressive Disorder, Treatment-Resistant, Depressive Disorder, Depressive Episode
- Trial name
- ODEN (NCT05641623)
- Testing
- OSU6162
- Where
- 4 sites in Sweden
- Volunteers
- 180 people
- Sponsor
- Göteborg University
Urinary Incontinence (UI)
HIFEM for Incontinence After Menopause High-Intensity Focused Electromagnetic (HIFEM)
It is not difficult to imagine that leaking urine affects life in many contexts. Unfortunately, it is everyday life for far too many people in our society.
- Trial name
- HIM2025 (NCT07260604)
- Testing
- Pelvic floor training as described in point a above, with the addition of HIFEM., Pelvic Floor exercises
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Göteborg University
Peri-Implantitis
Peri-implantitis - Reconstructive Surgical Therapy
The project will evaluate the potential benefit of the use of bone replacement graft as an adjunct to surgical therapy of peri-implantitis.
- Trial name
- NCT03077061
- Testing
- Open flap debridement, Bone replacement graft
- Where
- Sweden
- Volunteers
- 140 people
- Sponsor
- Göteborg University
Nociceptive Pain
Comparison of Different Objective Nociceptive Measurement Methods During Surgery
Traditionally, hemodynamic response e.g. pulse and blood pressure are used to evaluate pain in humans who are anesthetized. These values, however, can be affected by factors other than pain response .
- Trial name
- NCT05218551
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Göteborg University
Ectopic Tooth Eruption, Palatal Expansion Technique
The Effectiveness of Early Intervention to Correct the Position of PDC:s
Approximately 2-3% of children will have problems with one or both of their permanent or 'adult' canine teeth in the upper jaw. These canine teeth sometimes fail to erupt properly, because they are displaced into the roof of the…
- Conditions
- Ectopic Tooth Eruption, Palatal Expansion Technique, Randomized Clinical Trial
- Trial name
- PDC (NCT06267989)
- Testing
- Extraction of the primary canine teeth, Expansion
- Where
- 3 sites in Germany, Sweden and 1 more
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Peri-Implantitis
Air-polishing in the Treatment of Peri-implantitis
The aim of the present study is to evaluate the potential benefit of the adjunctive use of an air-polishing device in the non-surgical treatment of peri-implantitis as compared to mechanical infection control alone.
- Trial name
- NCT04847648
- Testing
- Air-polishing, Mechanical decontamination
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Göteborg University
Childhood Cancer, Communication
Pictorial Support in Person-centred Care for Children (PicPecc)
Introduction: Person-centred care is based on the assumption that every person has resources that should be used in the care situation.
- Conditions
- Childhood Cancer, Communication, Symptoms and Signs
- Trial name
- PicPecc (NCT04433650)
- Testing
- Pictorial support in person-centred care for children (PicPecc)
- Where
- Sweden
- Volunteers
- 29 people
- Sponsor
- Göteborg University
Appetite, Obesity and Obesity-related Medical Conditions
Metabolic Effects of Short-term Ultra-processed Food Intake (MEST-UPF)
The overall aim of this project is to study the effects of short-term high ultra-processed food intake, compared to nutrient- and energy density matched low ultra-processed food (UPF) intake, on energy intake and appetite.
- Trial name
- NCT07213245
- Testing
- Meal high in energy density, high in ultra-processed food, Meal high in energy density, low in ultra-processed food, Meal low in energy density, high in ultra-processed food
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Non-Small Cell Carcinoma of Lung
Aspects of Quality of Life During Adjuvant Oncological Treatment for Locally Advanced Lung Cancer Which Include Immune Checkpoint Inhibitor.
Current oncological treatment for patients with locally advanced lung cancer comprise adjuvant immunotherapy (immune checkpoint inhibitors-ICI) as an additional one-year treatment after chemoradiotherapy which increases overall…
- Trial name
- NCT07754409
- Where
- Sweden
- Volunteers
- 75 people
- Sponsor
- Göteborg University
Cardiometabolic Risk Factors, Microbiota
Health Effects of Ultra-processed Food Intake
Ultra-processed food (UPF) intake has been related to negative health effects and increased energy intake in previous intervention studies.
- Conditions
- Cardiometabolic Risk Factors, Microbiota, Diet Interventions
- Trial name
- UPFront (NCT07634159)
- Testing
- Diet high in UPF, Diet low in UPF
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Carbohydrate Intake and Exercise Performance
Carbohydrate Availability and Running Performance in Professional Male Footballers
The goal of this clinical trial is to learn how different daily carbohydrate intakes affect training performance in professional male football players during a pre-season training week.
- Trial name
- NCT07668726
- Testing
- High-Carbohydrate Beverage
- Where
- Sweden
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Healthy
Biomarker pAtterns Reflecting habITual fOod iNtakE: the BARITONE Project
The BARITONE study's overall aim is to understand how our eating habits affect our long-term health. By identifying biological traces in blood, urine and other samples - so-called biomarkers - the investigators want to be able to…
- Trial name
- BARITONE (NCT07128940)
- Testing
- Meat vs fish, Meat vs Vegetarian, Fish vs Vegetarian
- Where
- Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Blood Pressure Regulation
The Effects of Nitrate-Rich Mouthwash on Vascular Tone
High blood pressure (hypertension) is a major risk factor for cardiovascular disease. One important contributing factor to high blood pressure is reduced availability of nitric oxide (NO).
- Trial name
- NITRATONE (NCT07602764)
- Testing
- Nitrate-rich mouth rinse, Nitrate-rich drink
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Sick Leave
Assessment of Activity Limitations, a Basis for Understanding the Need for Sickness Certificate and Rehabilitation
In Sweden mental disorders have the highest proportion of sickness absence and sickness spells. One cause for this is proposed as the lack of knowledge on which activity limitations that have an impact on the ability to return to…
- Trial name
- NCT05772494
- Testing
- Assessment of activity limitations, SDO and DOA, Control group
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Göteborg University
Chronic Pain, Persistent Pain
Pleasant Touch Perception in Persistent Pain.
The goal of this observational study is to learn how individuals with chronic pain experience pleasant touch and how often they are exposed to such touch in their daily lives.
- Trial name
- NCT07551687
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Göteborg University