Clinical trials: sponsored by Göteborg University
Coronary Artery Disease, Heart Infarction
Effects of Personalized Training Program on Coronary Flow Reserve in Healthy Volunteers
This study investigates whether an individualized exercise program, including a personal trainer, can improve cardiovascular status quantified with ultrasound to assess coronary flow reserve and other non-invasive techniques.
- Trial name
- NCT02713724
- Testing
- physical exercise, limited physical exercise
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Obesity
Short- and Longterm Effects of Physical Activity and Dietary Restriction Postpartum
The study will investigate whether physical exercise, or dietary restrictions, or a combination of both, among overweight and obese postpartum women lead to a significantly larger reduction in weight in a longer perspective…
- Trial name
- LEVA (NCT01343238)
- Testing
- Diet, Exercise, Diet and Exercise
- Where
- Sweden
- Volunteers
- 76 people
- Sponsor
- Göteborg University
Barrett's Esophagus
Expression and Function of the Renin-Angiotensin System in the Esophagus
Barrett's esophagus (BE) is the major esophageal pre-neoplastic lesion in which dysplastic transformations eventually can lead to cancer development.
- Trial name
- NCT02879721
- Testing
- Candesartan, Enalapril
- Where
- Sweden
- Volunteers
- 33 people
- Sponsor
- Göteborg University
Type 2 Diabetes
Diabetes Prevention in Clinical Practice.
We randomize individuals with impaired glucose tolerance to one of three arms for degree of physical activity: 1. Continue with your current life style; 2. Ordinary life activities for increased physical activity; 3.
- Trial name
- DIAVIP (NCT01834378)
- Testing
- Low intensity intervention, High intensity intervention.
- Volunteers
- 96 people
- Sponsor
- Göteborg University
Mouth Diseases, Quality of Life
Prospective Studies on Oral Health and Quality of Life in Head and Neck Cancer Patients
Radiation therapy (RT) leads to a markedly reduced salivary secretion rate, which makes it difficult to eat and talk and it is a risk factor for oral disorders such as caries and mucosal infections.
- Conditions
- Mouth Diseases, Quality of Life, Secretion; Salivary Gland, Deficient
- Trial name
- NCT02870270
- Testing
- Cancer treatment
- Where
- Sweden
- Volunteers
- 33 people
- Sponsor
- Göteborg University
Obstructive Sleep Apnea, Sleep-Disordered Breathing
A Short Term Open, Randomized Cross-over Trial Exploring the Effect of Carbonic Anhydrase Inhibition by Acetazolamide on Sleep Apnea Associated Hypertension and Vascular Dysfunction
This is a short term open, randomized cross over trial to explore and compare the efficacy of pharmacological carbonic anhydrase (CA) inhibition on obstructive sleep apnea (OSA) related hypertension.
- Conditions
- Obstructive Sleep Apnea, Sleep-Disordered Breathing, Blood Pressure, Hypertension
- Trial name
- NCT02220803
- Testing
- Acetazolamide, nasal Continuous Positive Airway Pressure (nCPAP)
- Where
- Sweden
- Volunteers
- 13 people
- Sponsor
- Göteborg University
Depression
Management of Depression in Primary Care
Most people in Sweden with mild to moderate depression are treated in primary care, but follow-up is unstructured, and we know little about whether structured, follow-up would affect the prognosis for depression and working life.
- Trial name
- NCT01402206
- Testing
- Structured patient-centered follow up of depression
- Where
- Sweden
- Volunteers
- 258 people
- Sponsor
- Göteborg University
Ankylosing Spondylitis, Osteoporosis
Treatment With Alendronate in Patients With Ankylosing Spondylitis (AS)
This prospective study will assess the effects of treatment with alendronate in osteoporotic patients with ankylosing spondylitis.
- Trial name
- NCT01104987
- Testing
- alendronate
- Where
- Sweden
- Volunteers
- 16 people
- Sponsor
- Göteborg University
Ankylosing Spondylitis
Remicade in the Treatment of Patients With Active Ankylosing Spondylitis
The aim of the study was to evaluate the efficacy of infliximab (IFX) treatment, 5 mg/kg every 6 weeks, in patients with active ankylosing spondylitis (AS) and to determine whether IFX dose reduction and interval extension, 3…
- Trial name
- NCT01850121
- Testing
- Infliximab
- Where
- Sweden
- Volunteers
- 19 people
- Sponsor
- Göteborg University
Abortion, Habitual
RECAB-ASA; Treatment of Recurrent Abortion With Aspirin
The aim of this study is to examine whether treatment with 75 mg aspirin daily compared with placebo could reduce the risk for a new miscarriage.
- Trial name
- RECAB-ASA (NCT02823743)
- Testing
- Aspirin
- Volunteers
- 400 people
- Sponsor
- Göteborg University
Hyposalivation
The Effect of Probiotic Streptococci and pH-rising Components on the Oral Microbial Flora
The test group consisted of eighteen subjects with hyposalivation used probiotic tablets (≥ 4/day) and gel (once a week) (streptococci, bicarbonate and carbamide) for 3 months and 9 used placebo tablets and gel.
- Trial name
- NCT02677480
- Testing
- Test group, probiotic tablets and gel
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Göteborg University
Abdominal Obesity
Rosuvastatin in Visceral Adiposity
The purpose of this study is to investigate whether 6 months treatment with the cholesterol-lowering drug rosuvastatin may reduce visceral fat tissue in obese middle aged men.
- Trial name
- RIVIERA (NCT01068626)
- Testing
- Rosuvastatin
- Where
- Sweden
- Volunteers
- 54 people
- Sponsor
- Göteborg University
Irritable Bowel Syndrome
Traditional Dietary Advice Versus a Low FODMAP Diet Intake in IBS Patients
The purpose of this study is to to assess if the new diet with a low-FODMAP(Fermented Oligo-, Di-, Monosaccharides And Polyols) -content yields a milder symptom picture in IBS patients compared to traditionally dietary advice in…
- Trial name
- KRIBS (NCT02107625)
- Testing
- Diet A i.e. Low FODMAP diet, Diet B, i.e. Traditional IBS diet
- Volunteers
- 75 people
- Sponsor
- Göteborg University
Acute Low Back Pain, Physical Activity
Acute Low Back Pain: Causes, Mechanisms, Treatment and Followup
The purpose of this study is to investigate acute low back pain, its origin, mechanisms, the cause of pain, evaluation of treatments and development.
- Trial name
- ALBP (NCT02517762)
- Testing
- Physical activity
- Volunteers
- 99 people
- Sponsor
- Göteborg University
Slow Labour Progress
Labour Augmentation by Means of Oxytocin - Obstetric Outcome and Women's Experiences
Slow labour progress is common in nulliparous women and is associated with childbirth complications and negative birth experiences. Oxytocin augmentation is widely used to treat slow labour despite associated risks for the fetus.
- Trial name
- NCT01263158
- Testing
- Expectancy of standard oxytocin treatment
- Where
- Sweden
- Volunteers
- 2,072 people
- Sponsor
- Göteborg University
Ankylosing Spondylitis
Clinical Trial of Osteoporosis in Ankylosing Spondylitis
This is an observational study aiming to study the prevalence and risk factors for osteoporosis and vertebral fractures in patients with ankylosing spondylitis attending three Rheumatology clinics in Western Sweden.
- Trial name
- NCT00858819
- Where
- Sweden
- Volunteers
- 250 people
- Sponsor
- Göteborg University
Hepatitis C
Ribavirin Loading Dose or Priming and Concentration Targeting for HCV Genotype 1
This is a randomized, open-label, parallel group, multicenter pilot study evaluating the efficacy and safety of alternative dosing of ribavirin vs.
- Trial name
- RibaC (NCT01226771)
- Testing
- Ribavirin "loading" dose given, "Priming" dose of ribavirin given, Group C ("Standard-of-Care")
- Where
- Sweden
- Volunteers
- 105 people
- Sponsor
- Göteborg University
Cervical Dysplasia
Effect of Fee on Attendance in Cervical Cancer Screening
Several reasons can explain non-attendance in cervical cancer screening. In low resource settings the attendance is even lower. The effect of fee as contributing reason of non attendance has not been studied before why the…
- Trial name
- NCT02378324
- Testing
- Screening without fee
- Volunteers
- 3,124 people
- Sponsor
- Göteborg University
Pain
Local Infiltration Analgesia After Abdominal Hysterectomy
The aim of the study is to evaluate traditional analgesic therapy after abdominal hysterectomy with single infiltration of local anesthetics in the surgical area at the end of surgery.
- Trial name
- LIA (NCT01782781)
- Testing
- ropivacaine, ketorelac and epinephrine
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Göteborg University
Peri-Implantitis
Surgical Treatment of Peri-implantitis
The objective of this randomized controlled clinical trial is to evaluate the outcome of treatment of peri-implantitis with or without systemic antibiotics.
- Trial name
- NCT01857804
- Testing
- Amoxicillin, Chlorhexidine gluconate, Saline
- Where
- Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Göteborg University