Clinical trials: sponsored by Göteborg University
Type1 Diabetes Mellitus
Ixekizumab Diabetes Intervention Trial (I-DIT)
Although the clinical onset of type 1 diabetes (T1D) is acute, the progression of T1D occurs over many years often in a patchy manner with inflammation in certain lobes of the pancreas, leaving other lobes unaffected and…
- Trial name
- I-DIT (NCT04589325)
- Testing
- Ixekizumab
- Where
- 17 sites in Sweden
- Volunteers
- 127 people
- Sponsor
- Göteborg University
Behavior, Child, Parenting
The Effect and Experience of the Parental Program AFFEKT
This project is the first to evaluate the effect and experience of the parent program AFFEKT, through a randomized controlled trial and qualitative study, within primary health care.
- Conditions
- Behavior, Child, Parenting, Parent-Child Relations, Stress
- Trial name
- NCT05983705
- Testing
- AFFEKT - a manual based brief parent program for parents of children (aged 6-12 years) with externalizing behaviors.
- Where
- Sweden
- Volunteers
- 198 people
- Sponsor
- Göteborg University
Pediatric Obesity, Obesity
OBDIPHY (OBesity DIgital-PHYsical Care Study)
This is a prospective randomized controlled multicentre non-inferiority trial. The aim of this study to evaluate digi-physical care compared to regular physical/in person care and investigate if digi-physical care can be an equal…
- Conditions
- Pediatric Obesity, Obesity, Adolescent Obesity, Lifestyle Risk Reduction
- Trial name
- OBDIPHY (NCT05247918)
- Testing
- Digital-physical care, Treatment as usual
- Where
- 5 sites in Sweden
- Volunteers
- 102 people
- Sponsor
- Göteborg University
Vitamin D Deficiency, Vitamin D3 Deficiency
PREDIN: Pregnancy and Vitamin D Intervention Study
Vitamin D deficiency is common among certain risk groups in Sweden, and occurs approximately in every tenth pregnant woman.The aim of the randomized double-blind controlled trial Pregnancy vitamin D intervention (PREDIN) is to…
- Conditions
- Vitamin D Deficiency, Vitamin D3 Deficiency, Pregnancy Complications
- Trial name
- PREDIN (NCT05329428)
- Testing
- Vitamin D Supplementation 20 µg/day, Vitamin D Supplementation 40 µg/day, Usual Antenatal Care
- Where
- Sweden
- Volunteers
- 105 people
- Sponsor
- Göteborg University
PANS Pediatric Acute-Onset Neuropsychiatric Syndrome
Open-label Trial of IVIG in Children With PANS
Open-label prospective trial to study efficacy, safety and tolerability of intravenous immunoglobulin (IVIG) once monthly for 6 months in children and adolescents with PANS. Number of subjects: 10. Age range: 4-17 years.
- Trial name
- NCT04609761
- Testing
- Privigen Injectable Product (Intravenous Immunoglobulin)
- Where
- Sweden
- Volunteers
- 17 people
- Sponsor
- Göteborg University
Behavior Problems, Neurodevelopmental Disorders
RCT of PR-ESSENCE - a Problem Solving Model for Youth With Challenging Behavior in Special (SiS) Treatment Homes
Randomized controlled trial of PR-ESSENCE treatment for youth with challenging behavior in two youth treatment homes, including 60-70 youth.
- Trial name
- NCT04505072
- Testing
- PR-ESSENCE, Treatment as usual
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Göteborg University
Obesity (Disorder), Child Obesity
Pharmacological Treatment - An Overview of Its Role in Managing Childhood Obesity
The aim of the study is to examine the effects of pharmacological treatment for obesity on BMI trajectories and metabolic markers among patients in routine clinical care. A retrospective observational study.
- Trial name
- NCT07304141
- Testing
- Liraglutide 3 mg (Saxenda)
- Where
- Sweden
- Volunteers
- 128 people
- Sponsor
- Göteborg University
Ovarian Cancer, Complication
Hysterectomy and OPPortunistic SAlpingectomy
HOPPSA is a register based randomized controlled trial (R-RCT), with the objective to examine if opportunistic salpingectomy compared with no salpingectomy, at the time of hysterectomy for a benign reason has no increased risk of…
- Trial name
- HOPPSA (NCT03045965)
- Testing
- Salpingectomy
- Where
- Sweden
- Volunteers
- 4,400 people
- Sponsor
- Göteborg University
Cardiometabolic Risk Factors, Inflammation
FILIP: Fat Intake, Inflammation and LIPids
Low-grade inflammation is involved in the pathogenesis of type 2 diabetes and cardiovascular disease. Increasing evidence suggests that dietary intake may be involved in the inflammatory process.
- Conditions
- Cardiometabolic Risk Factors, Inflammation, Microbiota
- Trial name
- FILIP (NCT06640036)
- Testing
- Rapeseed oil, Butter, Coconut oil
- Where
- Sweden
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Obesity and Obesity-related Medical Conditions, Appetite
Effects of Meal Characteristics on Appetite
The overall aim of the study is to determine effects of different meal characteristics on energy intake, eating rate and appetite.
- Trial name
- NCT07178405
- Testing
- Meal low in energy density, low in ultra-processed food, Meal low in energy density, high in ultra-processed food, Meal high in energy density, low in ultra-processed food
- Where
- Sweden
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Obesity, Pain, Postoperative
Effects of an Opioid Free/Sparing Care Pathway for Patients Undergoing Obesity Surgery
The opioid consumption has exploded in the western world, and for some patient populations such as obese patients, patients with sleep apnoea or patients undergoing cancer treatment, opioid-sparing/ opioid-free strategies could…
- Trial name
- OS-PCC (NCT03756961)
- Testing
- Dexmedetomidine, Person-centred care (PCC), Esketamine
- Where
- 2 sites in Sweden
- Volunteers
- 220 people
- Sponsor
- Göteborg University
Stroke
Evaluation of the Ronnie Gardiner Method in Individuals With Stroke in Late Phase of Recovery
Stroke is a common condition that often leads to long-term disabilities, significantly affecting individuals' quality of life and imposing substantial societal costs.
- Trial name
- NCT06979050
- Testing
- The Ronnie Gardiner Method
- Where
- 3 sites in Sweden
- Volunteers
- 80 people
- Sponsor
- Göteborg University
Normal Pressure Hydrocephalus Patients, Normal Pressure Hydrocephalus
Non-invasive Diagnostics of Shunt Obstruction in Adult Hydrocephalus
The goal of this RCT is to test whether volumetric assessment of magnetic resonance imaging (MRI) could diagnose shunt obstruction in Adult Hydrocephalus patients, and in addition to explore correlations of blood biomarkers…
- Trial name
- NCT07172841
- Testing
- Intervention group "Virtual OFF", Control group (no change in shunt setting)
- Volunteers
- 60 people
- Sponsor
- Göteborg University
Coronary Syndrome, Pediatric
Cerebral Oxygenation and Burst Suppression
investigators want to observe a group of pediatric patients who are going to undergo open thoracic surgery at Queen Silvia's child and youth hospital, Sahlgrenska University Hospital.
- Trial name
- NCT04206683
- Where
- Sweden
- Volunteers
- 15 people
- Sponsor
- Göteborg University
Thyroid Gland; Node, Pregnancy
Swedish Iodine in Pregnancy and Development in Children (SWIDDICH) Study
THE ULTIMATE GOAL of this project is to answer the question "In MILD IODINE DEFICIENCY (ID), should a tablet with vitamins and minerals, including 150 μg iodine/day be administered to pregnant women with a normal diet, to attain…
- Conditions
- Thyroid Gland; Node, Pregnancy, Cognitive Developmental Delay
- Trial name
- SWIDDICH (NCT02378246)
- Testing
- Iodine
- Where
- 4 sites in Sweden
- Volunteers
- 1,337 people
- Sponsor
- Göteborg University
Cancer Uterus Cervix
Respiration After Robot Assisted Laparoscopic Hysterectomy
The study will investigate how respiratory function is affected by robot-assisted surgery. Previous studies have investigated the impact after open and laparoscopic surgery, but there are no studies yet after robot-assisted…
- Trial name
- REHYR (NCT06806280)
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Göteborg University
Gingiva Atrophy
Effectiveness of Meshed Free Gingival Graft for Widening of Keratinized Tissues
The overall objective of this project is to evaluate, over a period of 1 year, the outcomes of either conventional free gingival graft (FGG) or mesh-FGG to increase the width of keratinized mucosa (KM) at implant sites.
- Trial name
- NCT06037694
- Testing
- Conventional Free Gingival Graft, 'Mesh Free Gingival Graft
- Where
- United Arab Emirates
- Volunteers
- 30 people
- Sponsor
- Göteborg University
Periodontitis, Furcation Defects
Use of a Bone Substitute Material in the Surgical Therapy of Furcation Defects
The aim of this randomized clinical trial is to evaluate the potential benefit of the use of a bone substitute material in the treatment of furcation degree II-involved molars.
- Trial name
- NCT06270303
- Testing
- Access flap & surgical debridement, Application of bone substitute material (BioOss Collagen)
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Göteborg University
Healthy Conditions
Diet Induced Intestinal Mucosal Adaptation
Human beings are 'omnivores' meaning that all principal components of food (i.e. the macronutrients: carbohydrates, fat, proteins) can be assimilated by the gastrointestinal tract.
- Trial name
- NCT02088853
- Testing
- high fat diet (hfd), then high carbohydrate diet, high carbohydrate diet, then high fat diet
- Where
- Sweden
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Childhood Obesity, Physical Inactivity
The Halland Obesity Municipal Effort for Children
A retrospective study to investigate the method called The Halland Obesity Municipal Effort for children. All children participating in the intervention since the start of this specific method will be eligible for inclusion.
- Conditions
- Childhood Obesity, Physical Inactivity, Physical Activity, BMI
- Trial name
- NCT05254938
- Testing
- The Halland Obesity Municipal Effort for children
- Where
- Sweden
- Volunteers
- 141 people
- Sponsor
- Göteborg University