Clinical trials: sponsored by Göteborg University
Heat Stress, Kidney Injury
Does Probiotic Supplementation Prevent Kidney Injury During Strenuous Physical Exercise?
Severe heat strain arising from intense physical work under climate conditions that does not allow sufficient heat dissipation may lead to heat stroke.
- Trial name
- NCT04985292
- Testing
- Probiotic, Lactobacillus
- Where
- Sweden
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Congenital Heart Defects
Is Levosimendan Superior to Milrinone Regarding Acute Kidney Injury After Cardiac Surgery for Congenital Heart Disease?
The aim of the study is to assess the ability of Levosimendan to reduce the postoperative acute kidney injury in pediatric patients undergoing surgery for congenital heart disease (CHDs).
- Trial name
- MiLe-1 (NCT02232399)
- Testing
- Levosimendan, Milrinone
- Where
- 2 sites in Finland, Sweden
- Volunteers
- 72 people
- Sponsor
- Göteborg University
Thyroid Gland; Node, Lactation
Iodine Status in Swedish Lactating Women - Effect of Iodine Supplementation in the Thyroid Function of Mother and Infant
The aim of the study is to measure urinary milk iodine concentration (MIC), iodine concentration (UIC), thyroid hormones (TSH, FT4) and thyroperoxidase antibodies (TPOab) in breast-feeding women, and UIC in their nursing infants…
- Trial name
- NCT02378233
- Testing
- iodine
- Where
- Sweden
- Volunteers
- 77 people
- Sponsor
- Göteborg University
Cystic Fibrosis
Thoracic Mobility in Cystic Fibrosis Care
Cystic fibrosis (CF) is an inherited, genetic disease of the body's mucus-producing glands that primarily affects the lungs and gastrointestinal tract.
- Trial name
- NCT04696198
- Testing
- Manual Therapy Intervention, Standard care
- Where
- Sweden
- Volunteers
- 63 people
- Sponsor
- Göteborg University
Pulmonary Embolism
Effects of Information and Breathing Technique - for Patients With Respiratory Pain in Acute Pulmonary Embolism.
Acute pulmonary embolism (PE) is a serious disease and the third most common cardiovascular disease following myocardial infarction and stroke. The most common symptoms of acute PE are breathlessness and respiratory pain.
- Trial name
- NCT03375723
- Testing
- Information on anatomy and physiology, and breathing technique, Usual care treatment
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Aortic Aneurysm, Abdominal, Complication of Surgical Procedure
Myocardial Injury in Treatment of AAA
Comparison of elective infrarenal aneurysm surgery with open and endovascular technique, respectively, for subclinical ischemic myocardial injury detectable with troponin T and/or 3-channel Holter ECG with ST analysis
- Conditions
- Aortic Aneurysm, Abdominal, Complication of Surgical Procedure, Myocardium; Ischemic
- Trial name
- TREATROP (NCT04292652)
- Testing
- AAA surgery
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Göteborg University
Inflammatory Response, Inflammation
Fat Quality and Postprandial Inflammation
This aim of this randomized controlled postprandial study is to compare the effects of four different far sources (butter, coconut, corn oil and flax seed oil) on postprandial inflammation and metabolic response.
- Trial name
- PI:fat (NCT05674708)
- Testing
- Fat intake
- Where
- Sweden
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Severe Obesity
Bypass Equipoise Sleeve Trial (BEST)
This is nationwide registry-based randomised clinical multicenter trial in which patients will be randomised to gastric bypass (RYGB) or sleeve gastrectomy (SG).
- Trial name
- BEST (NCT02767505)
- Testing
- gastric bypass, Sleeve gastrectomy
- Where
- 21 sites in Norway, Sweden
- Volunteers
- 1,752 people
- Sponsor
- Göteborg University
Glaucoma Capsulare, Genetic Predisposition to Disease
Genetic and Risk Factors in Exfoliation Glaucoma Patients
Prospective non-randomised cohort study enrolling patients with exfoliation glaucoma. All patients were ophthalmological examined at inclusion. Blood samples were taken for genetic analysis.
- Conditions
- Glaucoma Capsulare, Genetic Predisposition to Disease, Risk Reduction
- Trial name
- NCT06237764
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 130 people
- Sponsor
- Göteborg University
Hypomineralization of Enamel, Dental Fear
Analysis of Treatment Outcomes in Patients Affected by Molar-Incisor Hypomineralization (MIH)
The aim is to long-term evaluate extraction or restoration therapy, of first permanent molars with extensive treatment needs as a result of severe MIH in a national multicenter study concerning dental fear and anxiety, oral…
- Conditions
- Hypomineralization of Enamel, Dental Fear, Quality of Life
- Trial name
- GuREx-MIH (NCT06228989)
- Testing
- Restorative therapy, Extraction therapy
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Noise Exposure, Sleep Disturbance
Low Particle Emission and Low Noise Tyres
This study will investigate the biological mechanisms linking sleep disruption by noise and the development of disease. In a laboratory sleep study, the investigators will play synthesised automotive tyre sounds, investigating…
- Conditions
- Noise Exposure, Sleep Disturbance, Sleep Hygiene, Metabolic Disturbance
- Trial name
- LEON-T (NCT05611619)
- Testing
- Tyre noise - continuous flow, Tyre noise - discrete events, High noise level
- Where
- Sweden
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Diabetes Mellitus, Type 2, Physical Activity
Effects of Measurement of Handgrip Strength on Physical Activity Level for Patients With Diabetes Type 2
Background: It is recommended that patients with diabetes type 2 keep themselves physically active and it is known that good muscular strength has a positive effect on these patients.
- Conditions
- Diabetes Mellitus, Type 2, Physical Activity, Muscular Weakness
- Trial name
- NCT03693521
- Testing
- Handgrip strength measurement, Standard care
- Where
- 7 sites in Sweden
- Volunteers
- 334 people
- Sponsor
- Göteborg University
Intensive Care (ICU), Mobilization
Physiological Response and Experience Between Sitting in Bed and Sitting in a Chair in ICU
Background: In the work with early mobilization (EM), in intensive care, several types of EM are used A sitting in bed in semi- Fowler's position, sitting on the edge of the bed, and sitting in a chair.
- Trial name
- NCT05118529
- Testing
- Routine care
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Göteborg University
Critical Illness
Limitations and Mortality in Intensive Care
This is an observational prospective pilot-study that investigates which patient-related variables that predict a decision to limit life sustaining treatments.
- Trial name
- LIMO (NCT04228380)
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Göteborg University
Oesophageal Cancer
Effects of Increased Physical Activity Before Thoracoabdominal Esophageal Surgery
Thoracoabdominal oesophageal resection for cancer is a procedure with high risks for complications, and patients' preoperative status is a crucial factor for outcome.
- Trial name
- NCT03452319
- Testing
- Pretraining, Usual care
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Göteborg University
Depression
Care Manager - Coordinating Care for Person Centered Management of Depression in Primary Care
The aim of the project is to explore if a complementary addition of a care manager for depression treatment in the primary care setting has positive effects concerning reduction of the patients' depressive symptoms as well as…
- Trial name
- PRIM-CARE (NCT02378272)
- Testing
- care manager for depression
- Where
- Sweden
- Volunteers
- 376 people
- Sponsor
- Göteborg University
Vitamin D Deficiency, Body Composition
GraviD-child Follow-up of the Children´s Health, Growth and Development Within the GraviD-study
GraviD is a multi-ethnic population-based pregnancy cohort. Pregnant women were invited to participate in the GraviD study when registering for antenatal care in parts of the region of Västra Götaland in Sweden in 2013-2014.
- Conditions
- Vitamin D Deficiency, Body Composition, Vascular Health, Cardiometabolic Risk
- Trial name
- NCT05228925
- Testing
- Maternal vitamin D status
- Where
- Sweden
- Volunteers
- 172 people
- Sponsor
- Göteborg University
Chronic Pain
Early Accessible Person-centred Rehabilitation for Patients With Chronic Pain
The goal of the research project EAPER-P is to evaluate PCC person-centred care (PCC) in the form of a combined eHealth and telephone support for patents with chronic pain.
- Trial name
- EAPER-P (NCT04706195)
- Testing
- Person-centred care at distance through an eHealth platform
- Where
- Sweden
- Volunteers
- 220 people
- Sponsor
- Göteborg University
Surgical Adhesions, Intestinal Obstruction
Band Adhesions in Relation to Previous Abdominal Surgery
This study investigates the prevalence of previous abdominal surgery in a cohort of patients operated for bowel obstruction and analyzes the causes of obstruction discovered at surgery.
- Conditions
- Surgical Adhesions, Intestinal Obstruction, Surgery Induced Tissue Adhesions
- Trial name
- NCT03663023
- Testing
- Intestinal obstruction
- Volunteers
- 196 people
- Sponsor
- Göteborg University
Musculoskeletal Diseases, Joint Instability
Wrist Stabilizing Exercise Versus Hand Orthotic Intervention for Persons With Hypermobility
The goal of this study is to investigate if a Wrist Stabilizing Exercise Programme, WSE, compared to Conventional Intervention use of orthosis in daily activities, HO in persons with Hypermobility Spectrum Disorders, HSD or…
- Trial name
- NCT05696041
- Testing
- Static strength training program or/and Dynamic strength training program of the hand
- Where
- Sweden
- Volunteers
- 169 people
- Sponsor
- Göteborg University