Clinical trials: sponsored by H. Lundbeck A/S
Migraine
A Trial Investigating Lu AG09222 With Ubrogepant in Participants With Migraine
The main goal of this trial is to learn more about the safety and tolerability of Lu AG09222 when taken together with ubrogepant.
- Trial name
- NCT06578585
- Testing
- Ubrogepant, Lu AG09222
- Where
- 4 sites in United States
- Volunteers
- 43 people
- Sponsor
- H. Lundbeck A/S
Healthy Participants
A Study Investigating Lu AG06474 in Healthy Young Participants
The purpose of this study is to investigate the safety of multiple oral doses of Lu AG06474, how well the doses are tolerated, and what the body does to the drug after administering it to healthy young participants.
- Trial name
- NCT05943327
- Testing
- Lu AG06474
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Healthy Participants
A Trial Investigating Lu AF82422 in Healthy Chinese and Caucasian Adults
The main goals of this trial are to learn more about a) the safety and tolerability of Lu AF82422 (any new or worsening medical issues the participants have with treatment), b) the immunogenicity of Lu AF82422 (the potential for…
- Trial name
- NCT06258720
- Testing
- Lu AF82422
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Healthy Participants
A Study Investigating the Movement of Lu AF28996 Into, Through, and Out of the Body of Healthy Men
The main goal of this study is to learn about how Lu AF28996 moves into, through, and out of the body after a single dose is given to healthy male participants.
- Trial name
- NCT06337110
- Testing
- Lu AF28996
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Cluster Headache, Episodic
Eptinezumab in Participants With Episodic Cluster Headache
The purpose of this study is to evaluate the efficacy of eptinezumab in participants with episodic Cluster Headache (eCH)
- Trial name
- ALLEVIATE (NCT04688775)
- Testing
- Eptinezumab
- Where
- 120 sites in United States, Belgium and 17 more
- Volunteers
- 231 people
- Sponsor
- H. Lundbeck A/S
Chronic Cluster Headache
A 1-year Trial to Inform About Long-term Exposure to Eptinezumab in Participants With Chronic Cluster Headache (cCH)
The main goal of this trial is to inform about long-term safety and tolerability of eptinezumab in participants with chronic cluster headache.
- Trial name
- CHRONICLE (NCT05064397)
- Testing
- Eptinezumab
- Where
- 31 sites in United States, Denmark and 7 more
- Volunteers
- 131 people
- Sponsor
- H. Lundbeck A/S
Healthy Participants
A Trial Investigating the Pain-relieving Properties of Lu AG06474 in Healthy Adult Participants
The main goal of this trial is to learn about the effect of Lu AG06474 on a battery of Evoked Pain Tests when a single dose is given to healthy adult participants.
- Trial name
- NCT06077786
- Testing
- Lu AG06474, Ibuprofen, Pregabalin
- Where
- Netherlands
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Healthy Participants
A Trial Investigating Lu AF28996 in Healthy Adult Participants
The purpose of this study is to investigate repeated doses of Lu AF28996 in healthy participants and co-administered with two other compounds, and in a separate cohort following co-administration with antibiotics, to see how well…
- Trial name
- NCT06277609
- Testing
- Lu AF28996, Acetylsalicylic Acid, Mefenamic Acid
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Migraine
Real World Effectiveness of Eptinezumab in Participants With Migraine
The purpose of this study is to examine how eptinezumab compares to other advanced preventive medications in a real-world community setting in adult participants with episodic migraine (EM) or chronic migraine (CM).
- Trial name
- EVEC (NCT05284019)
- Testing
- Eptinezumab, Erenumab, Onabotulinumtoxin-A
- Where
- 10 sites in United States
- Volunteers
- 32 people
- Sponsor
- H. Lundbeck A/S
Migraine
A Study With Lu AG09222 in Adults With Migraine Who Have Not Been Helped by Prior Preventive Treatments
Researchers are trying to learn whether a drug called Lu AG09222 can help prevent migraine headaches for people who have not been helped by other treatments that are used to prevent migraines.
- Trial name
- NCT05133323
- Testing
- Lu AG09222
- Where
- 28 sites in United States, Czechia and 4 more
- Volunteers
- 237 people
- Sponsor
- H. Lundbeck A/S
Healthy
Study in Healthy Subjects to Compare Two Tablet Formulations of Memantine (Ebixa®) in Fasted and Fed Conditions
The purpose of this study is to investigate the release of memantine into the bloodstream of two different formulations: one formulation containing lactose and one without lactose.
- Trial name
- NCT03670095
- Testing
- Lactose-free memantine, Memantine
- Where
- China
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Healthy
Bioequivalence Study to Compare Two Formulations of Deanxit®
The purpose of this study is to establish bioequivalence of flupentixol/meltracen, between a new film-coated tablet formulation and the marketed coated tablet formulation (Deanxit®), administered single dose in fasted and fed…
- Trial name
- NCT03472651
- Testing
- test treatment: flupentixol/melitracen, reference treatment: flupentixol/melitracen
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Parkinson Disease
A Trial Investigating Lu AF28996 in Adult Japanese Participants With Parkinson's Disease (PD)
This trial will evaluate the effects of Lu AF28996 in adult Japanese men and women with Parkinson's disease (PD). The main goals of the trial are to learn more about a) the safety and tolerability of Lu AF28996 (any new or…
- Trial name
- NCT06004180
- Testing
- Lu AF28996
- Where
- Japan
- Volunteers
- 6 people
- Sponsor
- H. Lundbeck A/S
Migraine in Children, Migraine
A Study in Children and Young People With Migraine to Learn What the Body Does to Eptinezumab
The purpose of the study is to investigate how the body absorbs, distributes, and get rid of eptinezumab when given directly into a vein.
- Trial name
- NCT04537429
- Testing
- Eptinezumab
- Where
- 9 sites in United States
- Volunteers
- 28 people
- Sponsor
- H. Lundbeck A/S
Migraine
A Study to Evaluate the Efficacy and Safety of Eptinezumab for the Prevention of Migraine in Participants That Are Not Helped by Previous Preventive Treatments
Evaluation of eptinezumab in the prevention of migraine in participants with unsuccessful prior preventive treatments.
- Trial name
- DELIVER (NCT04418765)
- Testing
- Eptinezumab
- Where
- 138 sites in United States, Belgium and 15 more
- Volunteers
- 892 people
- Sponsor
- H. Lundbeck A/S
Healthy Participants
A Study Investigating Lu AG22515 in Healthy Adults
The main goal of this study is to learn more about the safety of a drug called Lu AG22515. During the trial, healthy adult participants will receive a single dose of Lu AG22515 or a placebo (normal saline solution).
- Trial name
- NCT05136053
- Testing
- Lu AG22515, Immune System Activator
- Where
- 2 sites in United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
Symptomatic Neurogenic Orthostatic Hypotension
Sustained Effect of Droxidopa in Symptomatic Neurogenic Orthostatic Hypotension
To evaluate the time to treatment intervention in patients with Parkinson's Disease (PD), Multiple System Atrophy (MSA), Pure Autonomic Failure (PAF), Non-Diabetic Autonomic Neuropathy (NDAN) or Dopamine Beta Hydroxylase (DBH)…
- Trial name
- RESTORE (NCT02586623)
- Testing
- Droxidopa capsules
- Where
- 168 sites in United States
- Volunteers
- 453 people
- Sponsor
- H. Lundbeck A/S
Healthy, Alzheimer Disease
Study With Lu AF87908 in Healthy Participants and Participants With Alzheimer's Disease
The purpose of this study is to investigate the safety of a single dose of Lu AF87908, how well it is tolerated and what the body does to the drug in healthy participants and participants with Alzheimer's disease.
- Trial name
- NCT04149860
- Testing
- Lu AF87908
- Where
- 6 sites in United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S
PTSD
Lu AG06466 in Participants With Post Traumatic Stress Disorder (PTSD)
The purpose of this study is to investigate the effect of Lu AG06466 after multiple doses of 30 milligrams (mg) in participants with PTSD.
- Trial name
- NCT04597450
- Testing
- Lu AG06466
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- H. Lundbeck A/S
Healthy
A Study to Evaluate Lu AF90103 in Healthy Men
The purpose of this study is to investigate the safety and tolerability of Lu AF90103 and what the body does to Lu AF90103 after single doses of the drug administered directly into a vein.
- Trial name
- NCT04940949
- Testing
- Lu AF90103
- Where
- Netherlands
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- H. Lundbeck A/S