Clinical trials: sponsored by Hadassah Medical Organization
Aminoglycoside Dosing Based on PK/PD Characteristics
Adjustment of Aminoglycoside Dosing Based on Peak Serum Concentration and Bacterial Minimal Inhibitory Concentration
Aminoglycoside (AG) antibiotics have been in clinical use since the 1960s for treating various infections. The main safety concern related to AG use is nephrotoxicity.
- Trial name
- NCT05618457
- Testing
- Aminoglycoside dose adjustment
- Where
- Israel
- Volunteers
- 151 people
- Sponsor
- Hadassah Medical Organization
Rash Due to Epidermal Growth Factor Receptor Inhibitors
A Study to Examine the Effect of Reconval K1 Cream to Prevent Skin Toxicity From EGFRI
Vitamin K1 cream may prevent papulopustular rash induced by EGFRI given to metastatic colorectal cancer patients. This study will prospectively accrue metastatic colorectal patients receiving EGFRI and treat with reconval cream…
- Trial name
- EGFRI (NCT01763307)
- Testing
- RECONVAL CREAM
- Volunteers
- 18 people
- Sponsor
- Hadassah Medical Organization
Pain, Postoperative, Postoperative Nausea and Vomiting
Anesthetic Premedication With a Cannabis Extract (Cannapremed)
Clinical evidence about the effects of cannabis in a perioperative setting or for the management of acute pain is rather scarce, mostly consisting of case report-based opinions on adverse events during or after general anesthesia…
- Conditions
- Pain, Postoperative, Postoperative Nausea and Vomiting, Anxiety
- Trial name
- Cannapremed (NCT02283281)
- Testing
- Tetrahydrocannabinol, Dummy oromucosal
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Hadassah Medical Organization
Anxiety
The Effectiveness of Virtual Reality on Anxiety Reduction in Women Undergoing Elective Egg Cryopreservation.
A randomized trial assessing the effectiveness of virtual reality exposure prior to an oocyte retrieval procedure in terms of anxiety level .
- Trial name
- VRFORANXIETY (NCT06280222)
- Testing
- The VR instrument - Oculus Quest 2
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Dental Caries, Patient Compliance
A Study to Compare Caries Detection in the Pediatric Population Between the iTero Element 5D System and Bitewing Radiographs
This is a non-significant risk, single site, prospective clinical study. The study will be conducted in the department of pediatric dentistry of the faculty of dental medicine of the Hebrew university, Israel
- Trial name
- NCT05792631
- Testing
- Near infra red imaging
- Where
- Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Cesarean Delivery Affecting Fetus, Post Operative Bowel Function
Paula Method Versus Chewing Gum for Postoperative Recovery After Caesarean Section
The goal of this clinical trial is to compare the effectiveness of gum chewing vs Paula exercises in patients after cesarean delivery.
- Trial name
- NCT05729984
- Testing
- Paula exercises, Gum chewing
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Cesarean Section Complications, Uterine Bleeding
Surgical Incision Closure Method to Prevent Niche Formation After Cesarean Section- Randomized Controlled Trial
In the last decade we have been exposed to the complication of a caesarean section called a "niche". A niche is an anaerobic defect in the location of the cesarean section, which represents the discontinuity of the endometrium…
- Trial name
- NCT04766073
- Testing
- Niche prevention suture
- Where
- Israel
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Gaucher Disease Type 1
A Second-generation AI Based Therapeutic Regimen in Patients With Gaucher Disease Treated With Enzyme Replacement Therapy.
An open-labeled, prospective, single-center proof-of-concept study. Patients with Gaucher Disease aged 18-75 who received intravenous Enzyme Replacement Therapy once every two weeks were enrolled.
- Trial name
- NCT06050967
- Testing
- Enzyme replacement therapy for Gaucher disease in combination with altus care application
- Where
- Israel
- Volunteers
- 5 people
- Sponsor
- Hadassah Medical Organization
Acute Decompensated Heart Failure, Cytokine Storm
Asses the Anti-inflammatory Effects of Short Term Copaxone Therapy on Patients the Acute Decompensated Heart Failure
Assess the anti-inflammatory effects of short-term Copaxone therapy on patients with acute decompensated heart failure. Trial Design An open-label, randomized, prospective trial of patients hospitalized due to acute…
- Conditions
- Acute Decompensated Heart Failure, Cytokine Storm, Inflammatory Response, Heart Failure
- Trial name
- Copaxone (NCT06003972)
- Testing
- Copaxone, guideline directed medical therapy (GDMT)
- Where
- Israel
- Volunteers
- 14 people
- Sponsor
- Hadassah Medical Organization
Sciatica, Spinal Stenosis of Lumbar Region
Prolotherapy Versus Epidural Steroid Injections (ESI) for Lumbar Pain Radiating to the Leg
The hypothesis is that in the treatment of low back pain (LBP) radiating to the leg, the long-term results of prolotherapy are more effective than those of the current conventional treatment: epidural steroid injections (ESI).
- Conditions
- Sciatica, Spinal Stenosis of Lumbar Region, Degeneration of Lumbar or Lumbosacral Intervertebral Disc
- Trial name
- NCT01934868
- Testing
- prolotherapy solution of 20% dextrose, Epidural Steroid Injection
- Where
- Israel
- Volunteers
- 110 people
- Sponsor
- Hadassah Medical Organization
Sedentary Behavior
Do Implementation Intentions Increase Average Daily Step Count.
Cardiovascular disease is the second major cause of death for women in Israel and the leading cause of death among women worldwide.
- Trial name
- NCT04259710
- Testing
- Goal-setting intervention, Goal setting with implementation intentions, Pedometer only
- Where
- Israel
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Health Literacy
eHealth Literacy Workshops in the Community
This study aims to implement and evaluate an eHeath literacy workshop that trains women to take advantage of the digital media available to them so that they can use it to their advantage- set appointments, search for doctors…
- Trial name
- NCT04960917
- Testing
- Evaluation of ehealth literacy workshop
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Cardiovascular Diseases, Lifestyle Risk Reduction
Lifestyle Intervention Plus Emotion Regulation Group Intervention Impact on Women's Cardiovascular Risk Reduction
This pilot study aims to demonstrate that emotional regulation (ER) is a valuable supplement to a documented and effective group-based lifestyle intervention on cardiovascular disease risk reduction maintenance in a non-clinical…
- Trial name
- NCT03167489
- Testing
- Lifestyle Plus Emotional Regulation
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Sedentary Behavior, Risk Reduction
Training Health Promotion Women Community Leaders
Goal of the Program: To develop personal and group ability for participants in the DPP to plan and implement health promotion programs. Objectives: 1.
- Trial name
- NCT04500977
- Testing
- leadership empowerment
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Obesity, Childhood, Health Behavior
School-Based Intervention Program to Promote Healthy Eating and Physical Activity
The purpose of this research is to develop, apply, and evaluate a school-based intervention program in East Jerusalem schools, designed to increase knowledge and to improve the attitudes and healthy behavior of schoolchildren…
- Conditions
- Obesity, Childhood, Health Behavior, Physical Activity, Dietary Habits
- Trial name
- NCT03205293
- Testing
- Intervention Program to Promote Healthy Eating and Physical Activity among Palestinian Female Schoolchildren
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Diabetes, Health Behaviors
Community-Based Lifestyle Intervention for Diabetes Prevention in Arab Women
Arab women present increased risk for diabetes, with a 70% greater risk for adult-onset diabetes and a significantly younger age at onset compared with Jewish Israelis.
- Trial name
- CBLI (NCT03358797)
- Testing
- Attention-control, Community based intervention with resilience training, intervention-HPP
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Sedentary Behavior, Nutritional and Metabolic Disease
A Pilot Program Measuring Effectiveness of Health Coaching Interventions
Women will participate in a workshop within a group and individual meetings. the workshop will include providing information regarding guidelines for healthy eating, engaging in physical activity, personal training tools to build…
- Trial name
- NCT04297189
- Testing
- Coaching and health information intervention
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Hadassah Medical Organization
Sedentary Behavior, Risk Reduction
Achievement and Adherence to Behavioral Health Goals in the Setting of Patient-Directed Goal Choice
Health care decisions should include patients' health outcome goals and care preferences so as to enable a unified set of individualized patient outcome goals, rather than disparate disease-specific goals that do not reflect…
- Trial name
- NCT04294381
- Testing
- Decision tool
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Hadassah Medical Organization
Lifestyle Risk Reduction, Health Knowledge, Attitudes, Practice
Impact of Employee Health Promotion Course on Health Promotion in the Work Place.
People of working age spend most of their day at work, and usually have less time to participate in other activities, the work day in Israel being one of the longest in the OECD.
- Conditions
- Lifestyle Risk Reduction, Health Knowledge, Attitudes, Practice, Empowerment
- Trial name
- NCT03295136
- Testing
- Health Promotion Training for Women Employees
- Where
- Israel
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Cardiovascular Diseases, Health Behavior
Evaluation of a Socio-ecological Cardiovascular Disease Prevention Intervention for Ultra-Orthodox Jewish Hasidic Women
The purpose of this research study is to design, implement, and evaluate a community level, socio-ecological based CVD prevention intervention using a participatory approach for women in a homogeneous ultra-Orthodox Jewish…
- Trial name
- NCT03201523
- Testing
- Socio-ecologial, community-based intervention
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization