Clinical trials: sponsored by Henry Ford Health System
Osteoarthritis (OA) of the Knee
Novel Extended-Release Bupivacaine Polymer for Sustained Pain Relief Following Total Knee Arthroplasty
Participants are being invited to take part in a research study about pain control after total knee replacement surgery (also called total knee arthroplasty or TKA).
- Trial name
- NCT07775248
- Testing
- Periarticular Injection, Adductor Canal Block, Bupivacaine-Meloxicam
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Henry Ford Health System
Amyloidosis
Carpal Tunnel Release With Risk Factors for Amyloidosis
Bilateral carpal tunnel syndrome has been demonstrated in previous literature to be a warning sign for potential amyloidosis. One study has been performed in which patients with bilateral carpal tunnel syndrome underwent tissue…
- Trial name
- NCT05793320
- Testing
- Carpal Tunnel Release Surgery
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Henry Ford Health System
Arthroplasty, Replacement, Knee, Arthroplasty, Replacement, Hip
Sleep Patterns After Total Joint Replacement Surgery
The purpose of this study is to determine sleep patterns and sleep quality following total joint arthroplasty, in order to understand when patients should expect to return to baseline or improved sleep following total joint…
- Trial name
- NCT04896892
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Scope of Practice of Today's Hepatopancreatobiliary Surgeons
Current Scope of Practice of Today's Hepatopancreatobiliary Surgeons: A Survey of AHPBA Members
The development of multiple training pathways to foster competent hepatopancreatobiliary (HPB) surgeons has led to a diverse group of surgical subspecialists.
- Trial name
- NCT05075733
- Testing
- Survey
- Where
- United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Pleural Mesothelioma, Asbestos Exposure
Mesothelioma Early Detection by VOCs
This is a two phase study, The first phase (phase 1) will identify potential biomarkers among asbestos exposed individuals with pleural mesothelioma.
- Conditions
- Pleural Mesothelioma, Asbestos Exposure, Pleural Plaque
- Trial name
- MED-VOC (NCT04106973)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Henry Ford Health System
Covid-19
Comparison of the ID NOW and Accula Point-of-Care Assays for Detection of COVID-19
This study is a comparison of the ID Now COVID-19 (Abbott) assay to the Accula SARS-CoV-2 (Mesa Biotech) assay to assist in the identification of infection with COVID-19.
- Trial name
- NCT04403035
- Testing
- ID NOW vs. Accula
- Where
- United States
- Sponsor
- Henry Ford Health System
Pain, Opioid Use
Healing After Injury to Reduce Opioid Use and Pain Through Preventive Engagement
The goal of this proposed project is to optimize the adaptive psychological intervention and assess the feasibility and acceptability.
- Trial name
- HOPE (NCT07741201)
- Testing
- Computerized brief intervention, Psychological sessions, Opioid taper recommendations
- Volunteers
- 80 people
- Sponsor
- Henry Ford Health System
Gynecologic Disease
Bowel Preparation in Minimally Invasive Gynecologic Surgery
This is a prospective randomized study of patients who are scheduled to undergo minimally invasive robotic gynecologic surgery. Patients will be randomized to require either pre-surgical bowel preparation vs.
- Trial name
- NCT06820359
- Testing
- Bowel Preparation, No bowel preparation
- Where
- 2 sites in United States
- Sponsor
- Henry Ford Health System
Pelvic Organ Prolapse
Pain After Insufflation for Robotic Sacrocolpopexy (PAIRS) Trial
This study evaluates post-operative pain between different insufflation pressures during robotic-assisted sacrocolpopexy. Subjective pain and narcotic usage after surgery will be measured.
- Trial name
- NCT04858438
- Testing
- Insufflation during surgery
- Where
- United States
- Sponsor
- Henry Ford Health System
MASLD, Fatty Liver
Effects of Peanut Consumption on Adults With Metabolic Associated Fatty Liver Disease
The aim of this randomized interventional trial is to understand the effects of peanut consumption on patients with metabolic associated fatty liver.
- Trial name
- NCT07646197
- Testing
- Peanut consumption
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Henry Ford Health System
To Assess the Changes in Markers of Bone Turnover Over a Six Month Period After Epidural Steroid Inject, To Assess the Changes in Bone Mineral Density
Effect of Epidural Steroid Injection on Bone Mineral Density in Postmenopausal Women
To evaluate for the effect of corticosteroid epidural injections on bone mineral density in postmenopausal women. Candidates for the study: Post menopausal women between the ages of 55 and 80. No history of bone disease.
- Trial name
- NCT00941473
- Testing
- Triamcinilone (kenalog)
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Postpartum Depression
Prenatal Yoga to Prevent Postpartum Depression
Although psychological interventions exist for the prevention of PPD, a yoga-based intervention to prevent PPD among at-risk women utilizes a similar theoretical foundation (i.e., mindfulness), may be more acceptable to women of…
- Trial name
- PRY-D (NCT06004232)
- Testing
- Prenatal Yoga to Prevent Postpartum Depression (PRY-D) intervention, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Henry Ford Health System
Carpal Tunnel Syndrome
Corticosteroid Injection Effectiveness in Carpel Tunnel Patients With Negative or Mild EMG Studies
Carpal Tunnel Syndrome (CTS) is the most common nerve entrapment syndrome worldwide. There are currently no studies examining the effectiveness of corticosteroid injections in patients with normal (negative) EMG studies.
- Trial name
- NCT04737239
- Testing
- Corticosteroid injections for CTS treatment
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Henry Ford Health System
Lower Extremity Deep Vein Thrombosis
Effect of Emergency Department Bedside Compression Ultrasonography on Door-to-Disposition Time in Patients Suspicious for Lower Extremity Deep Venous Thrombosis
Comparing the disposition time of point of care ultrasound (POCUS) versus formal lower extremity doppler in emergency department patients.
- Trial name
- NCT05682040
- Testing
- Bedside Compression Ultrasonography
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Henry Ford Health System
Malignant Solid Neoplasm, Malignant Head and Neck Neoplasm
Symptom Management to Improve Completion of Patient-reported Outcome Measures
In this clinical trial, patient reported outcome (PRO) assessment completion is compared between patients (undergoing systemic therapy for head and neck or lung cancer) who receive additional symptoms monitoring and…
- Conditions
- Malignant Solid Neoplasm, Malignant Head and Neck Neoplasm, Malignant Lung Neoplasm
- Trial name
- NCT07723495
- Testing
- Monitoring of PROMIS symptoms and physical function, Monitoring of additional symptoms and symptom self-management
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Henry Ford Health System
Rectal Cancer
Treatment of Adenocarcinoma of the Rectum With Transanal Local Excision for Complete Responders
The current standard of care for rectal cancer has diminished local recurrence and enhanced survival. Quality of life, however, remains poor for many patients and the probability of distant recurrence is high.
- Trial name
- NCT03941366
- Testing
- Standard of care chemotherapy with the change for avoidance of extensive surgery
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Henry Ford Health System
Rectal Cancer
Watchful Waiting for Complete Responders to Therapy in Rectal Cancer
The purpose of this project is to determine if in a selected group of patients, at higher risk of wound dehiscence and other complications, treatment by local excision and management by a "watchful waiting" or an initial…
- Trial name
- NCT05526079
- Testing
- Watchfuf waiting
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Henry Ford Health System
Lung Cancer (NSCLC)
Perioperative Cemiplimab for Resectable Non-Small Cell Lung Cancer With High PD-L1
This is a single arm phase II trial enrolling patients with stage II-IIIA non-small cell lung cancer whose disease is deemed amenable for surgical resection and has a PD-L1 level of ≥50%.
- Trial name
- NCT07450183
- Testing
- Cemiplimab, Adjuvant chemotherapy
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Henry Ford Health System
Heart Failure
Project 4: ACHIEVE PATHFINDER
ACHIEVE-P4: PATHFINDER is a randomized, blinded clinical trial of portable air cleaners (PAC) provided at the time of hospital discharge to Heart Failure (HF) patients. It will be carried out at Henry Ford Hospitals.
- Trial name
- PATHFINDER (NCT06070428)
- Testing
- PAC provision at hospital discharge, Control non-intervention; PAC without filter
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Henry Ford Health System
Lung Cancers
Bright Light Therapy on Sleep Health in Lung Cancer Patients
The goal of this randomized intervention trial is to determine the effect of bright light therapy on sleep disturbance, as well as to investigate the impacts of bright light therapy on biological age measured by clinical…
- Trial name
- BLT (NCT07064395)
- Testing
- bright light
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Henry Ford Health System