Clinical trials: sponsored by Hospital for Special Surgery, New York
Cervical Radiculopathy
Cervical Radiculopathy Imaging Using MRN With Electrodiagnostic Correlation
This project will study patients with cervical radiculopathy. We will evaluate the combined diagnostic and prognostic value of magnetic resonance neurography (MRN), electrodiagnostic (EDX) studies, and historical and physical…
- Trial name
- NCT06971575
- Testing
- Magnetic resonance neurography
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Hospital for Special Surgery, New York
Same-day Discharge, Length of Stay
Preoperative Oral Hydration in the Ambulatory Arthroplasty Population
The purpose of this study is to investigate if the consumption of a complex carbohydrate drink preoperatively, decreases the length of stay and causes for failure to launch in patients undergoing ambulatory total joint…
- Trial name
- NCT05520593
- Testing
- Complex Carbohydrate Drink
- Where
- United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Artificial Intelligence (AI), Health Literacy
Comparing Original Patient Educational Materials vs. AI-Simplified Materials to Improve Patient Comprehension and Health Literacy
Poor health literacy and patient comprehension have been associated with adverse health outcomes. Patient educational materials (PEMs) are articles that are intended to assist patients in their understanding of a given medical…
- Conditions
- Artificial Intelligence (AI), Health Literacy, Patient Comprehension, Patient Educational Material
- Trial name
- NCT07505719
- Testing
- AI Simplification, Unmodified Patient Educational Material
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Surgical Wound, Post Operative Wound Infection
Early Versus Delayed Bathing of Orthopaedic Surgical Wounds
This is a single center randomized control trial assessing the effect of early versus delayed bathing on orthopaedic surgical wounds in patients undergoing surgical treatment of fractures.
- Trial name
- EVDB (NCT06014411)
- Testing
- Time to bathing (delayed), Time to bathing (early)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Hospital for Special Surgery, New York
Total Knee Arthroplasty, Opioid Use
Dronabinol in Total Knee Arthroplasty (TKA)
The goal of this double-blinded randomized controlled trial is to compare whether the addition of Dronabinol compared to a placebo will affect opioid intake in patients undergoing a total knee arthroplasty.
- Trial name
- NCT04734080
- Testing
- Dronabinol 5mg Cap
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Hospital for Special Surgery, New York
Patellar Dislocation, Recurrent, Patellar Dislocation
JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction
The goal of this observational study is to learn about the outcomes of medial patellofemoral ligament (MPFL) reconstruction for the treatment of recurrent patellar instability.
- Conditions
- Patellar Dislocation, Recurrent, Patellar Dislocation, Patellar Instability, Patellofemoral Dislocation
- Trial name
- NCT06883396
- Testing
- Medial Patellofemoral Ligament (MPFL) Reconstruction
- Where
- 16 sites in United States
- Volunteers
- 850 people
- Sponsor
- Hospital for Special Surgery, New York
Patellar Instability
Pediatric and Adolescent Patellar Instability
This is a multi-center, randomized controlled clinical trial, the purpose of which is to determine if patients age 25 and younger who undergo medial patellofemoral ligament (MPFL) reconstruction have lower rates of recurrent…
- Trial name
- PAPI (NCT02333825)
- Testing
- Medial patellofemoral ligament reconstruction surgery, Physical therapy and rehabilitation
- Volunteers
- 240 people
- Sponsor
- Hospital for Special Surgery, New York
Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis
PRP in ACLR to Prevent PTOA
The purpose of our study is to examine the effect of platelet-rich-plasma (PRP) injection on the short-term resolution of post-injury inflammation (biomarkers) and improvement in joint function in patients with acute ACL injury.
- Conditions
- Anterior Cruciate Ligament Injuries, Post-traumatic Osteoarthritis, PRP
- Trial name
- NCT05412381
- Testing
- platelet rich plasma (PRP) injection
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Hospital for Special Surgery, New York
Lumbar Spine Surgery
Comparing Patients' and Surgeons' Expectations of Lumbar Spine Surgery
The goals of this study are to assess concordance between the patient-surgeon pair regarding expectations of lumbar spine surgery.
- Trial name
- NCT02257554
- Testing
- education
- Where
- United States
- Volunteers
- 437 people
- Sponsor
- Hospital for Special Surgery, New York
Hip Osteoarthritis, Knee Osteoarthritis
Return to Golf After Orthopaedic Surgery
The GOLF study is a multicenter, prospective study with the goal to investigate golfers' return to the sport following hip, knee or shoulder arthroplasty.
- Conditions
- Hip Osteoarthritis, Knee Osteoarthritis, Shoulder Osteoarthritis
- Trial name
- NCT05675618
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 432 people
- Sponsor
- Hospital for Special Surgery, New York
Rheumatoid Arthritis
Analysis of T and B Cell Repertoire Changes in Response to Orencia® (Abatacept) in Rheumatoid Arthritis
The condition that will be studied is Rheumatoid Arthritis (RA), and in particular, RA patients with moderate to highly active disease who were prescribed Abatacept (Orencia®) (ABA) by their physician during their setting of care…
- Trial name
- NCT05782335
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Knee Arthroplasty
Hospital for Special Surgery Knee Arthroplasty Cohort
Total joint replacements are some of the most successful medical devices developed over the last fifty years. They enable millions of people to remain ambulatory and pain free, with minimal risk.
- Trial name
- NCT00454467
- Testing
- Baseline Questionnaire, Operative Data, Intra-operative data will be collected post-operatively
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- Hospital for Special Surgery, New York
Proximal Junctional Kyphosis, Adult Spinal Deformity Surgery
Post-Operative Thoracolumosacral Orthosis for PJK
Proximal junctional kyphosis (PJK) is a common post-operative radiographic finding after surgery for adult spinal deformity (ASD) patients.
- Conditions
- Proximal Junctional Kyphosis, Adult Spinal Deformity Surgery, Thoracolumbosacral Orthosis
- Trial name
- NCT06491030
- Testing
- Align PJK™ TLSO brace, Standard of Care
- Where
- 6 sites in United States
- Volunteers
- 84 people
- Sponsor
- Hospital for Special Surgery, New York
Complex Regional Pain Syndrome, Pain
CSS-SR Validation Study
Complex Regional Pain Syndrome (CRPS) is an orphan condition with no interventions proven effective in large-scale clinical trials.
- Trial name
- NCT06798493
- Testing
- Complex Regional Pain Syndrome (CRPS) Severity Score - Self Report
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Undifferentiated Connective Tissue Disease
Undifferentiated Connective Tissue Disease Registry
This registry has been established to gain a better understanding of the clinical and emotional presentations of patients with undifferentiated connective tissue disease.
- Trial name
- UCTD Registry (NCT02234388)
- Testing
- Observation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Hospital for Special Surgery, New York
Hypertension, Perioperative Hypertension
The Effectiveness of a Preoperative Blood Pressure Screening Program to Identify Undiagnosed Hypertension in Ambulatory Surgery Patients
Elevated blood pressure is the largest contributing risk factor to all-cause and cardiovascular mortality. According to the U.S. Preventive Services Task Force, hypertension affects nearly 30% of the adult population.
- Trial name
- Peri-op HTN (NCT03678207)
- Testing
- Anesthesiologist phone call
- Where
- United States
- Sponsor
- Hospital for Special Surgery, New York
Achilles Tendon Rupture, Database
Barriers to Efficient PACU Discharge at a Major Academic Orthopaedic Ambulatory Surgery Center
This is a retrospective chart review to determine the etiologies contributing to prolonged PACU discharge at a major Orthopedic Ambulatory Center
- Trial name
- NCT04356612
- Testing
- Chart Review
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Shoulder Arthroplasty
Hospital for Special Surgery Shoulder Arthroplasty Cohort
Total joint replacements are some of the most successful medical devices developed over the last fifty years. They enable millions of people to remain ambulatory and pain free, with minimal risk.
- Trial name
- NCT00527839
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- Hospital for Special Surgery, New York
Total Knee Replacement, Mediation
Mindfulness Meditation Intervention Study
The goal of this pilot study is to develop a randomized control trial study with sufficient power to definitely address if a preop mindfulness meditation intervention can improve post-total knee arthroplasty mental well-being or…
- Conditions
- Total Knee Replacement, Mediation, Feasibility
- Trial name
- NCT06180486
- Testing
- Mindfulness Meditation Intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hospital for Special Surgery, New York
ACL, Anterior Cruciate Ligament Injuries
Genicular Nerve Blocks for Anterior Cruciate Ligament Knee Surgery
The purpose of this randomized controlled trial is to assess a new analgesia regimen that includes the addition of genicular never blocks to our current standard regimen of peripheral nerve blocks, which includes an adductor…
- Trial name
- NCT05720949
- Testing
- Genicular Nerve Block with bupivacaine and preservative free dexamethasone
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Hospital for Special Surgery, New York