Clinical trials: sponsored by Huashan Hospital
Venous Thromboembolism
Study of Venous Thromboembolism Risk Profiles and Prophylaxis in Neurosurgical Inpatients
Venous thromboembolism (VTE), comprising deep venous thrombosis (DVT), pulmonary embolism (PE), or both, is a life-threatening complication in postoperative patients.
- Trial name
- VTE (NCT04257305)
- Where
- China
- Volunteers
- 9,010 people
- Sponsor
- Huashan Hospital
Chemical and Drug Induced Liver Injury
Hepatotoxicity of Antituberculosis Therapy (HAT) Study
Drug-induced liver injury (DILI) is a common side effect in antituberculosis therapy, which interuputs the treatment of TB and leads to a higher proportion of Multidrug-Resistence TB(MDR-TB).The study primalily aims to observe…
- Trial name
- HAT (NCT04159441)
- Testing
- None intervetion
- Volunteers
- 5,000 people
- Sponsor
- Huashan Hospital
Tuberculosis, Pulmonary
Evaluation of CRISPR-based Test for the Rapid Identification of TB in Pulmonary Tuberculosis Suspects
This observational Mycobacterium tuberculosis (MTB) diagnostics evaluation study is a prospective study of pulmonary TB suspects who are undergoing sputum or bronchoalveolar lavage fluid (BALF) evaluation for pulmonary TB.
- Trial name
- NCT04074369
- Testing
- CRISPR-based Test
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Huashan Hospital
Renal Failure, Nutrition Disorders
Etiology, Epidemiology and Prognostics of Acute Kidney Injury (AKI)
To investigate the etiology, epidemiology and prognostic factors of acute kidney injury. To find out risk factors that relate with the prognosis of acute kidney injury,focusing on inflammation, oxidative stress and nutritional…
- Trial name
- NCT00953992
- Where
- China
- Volunteers
- 651 people
- Sponsor
- Huashan Hospital
Bariatric Surgery, Mechanical Ventilation
Prospective Clinical Study of PCV and PCV-VG in Patients Undergoing Bariatric Surgery
This study compares the two mechanical ventilation strategies in obese patients undergoing bariatric surgery: pressure-controlled ventilation(PCV) and pressure-controlled ventilation volume-guaranteed（PCV-VG).
- Trial name
- NCT03150264
- Testing
- PCV-VG, PEEP5cmH₂O, PCV, PEEP5cmH₂O
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Huashan Hospital
End Stage Liver DIsease, Complication
Real World Study of End-stage Liver Disease in China
The aims of this study are exploring the current situation of end-stage liver disease in China, and the optimization of diagnosis and treatment. Liver cirrhosis often accompanied by a series of complications.
- Trial name
- NCT04037995
- Testing
- No intervation
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Huashan Hospital
Hepatitis, Chronic
Real World Study of Chronic Viral Hepatitis
This study is aimed to collect and analyze clinical data of patients with chronic viral hepatitis in the real world, to investigate the long-term outcome of these patients and to optimize treatment options based on these data.
- Trial name
- NCT04025944
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Huashan Hospital
Disorder of Consciousness, Minimally Conscious State
Spinal Cord Stimulation in Patients With Disorders of Consciousness
Disorders of consciousness(DOC) is the most serious complications and has been widely paid attention to by the government. DOC patients cause large social and economic burden to our society for there has no effective cure so far.
- Conditions
- Disorder of Consciousness, Minimally Conscious State, Vegetative State
- Trial name
- NCT04010838
- Testing
- spinal cord stimulation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Huashan Hospital
Hepatitis B
Maternal Antiviral Treatment and Infants Immunoprophylaxis in the Prevention of Mother-to-child Transmission
The effective control of nucleos(t)ide analogues for patients infected with hepatitis B has significantly curbed the horizontal transmission of hepatitis B.
- Trial name
- NCT03977987
- Testing
- nucleos(t)ide analogue
- Where
- China
- Volunteers
- 233 people
- Sponsor
- Huashan Hospital
Cerebellar Function, Transcranial Magnetic Stimulation
Enhanced Recovery After Surgery Using TMS on Cerebellar Language Area for Brain Tumor Patients
At present, the incidence of language dysfunction in patients with brain language area tumor in the first month after operation was 20%-40%.
- Conditions
- Cerebellar Function, Transcranial Magnetic Stimulation, Language Disorders
- Trial name
- NCT03974659
- Testing
- Transcranial magnetic stimulation
- Where
- 2 sites in China
- Volunteers
- 106 people
- Sponsor
- Huashan Hospital
Silicosis Tuberculosis
Short Course Rifapentine and Isoniazid for the Preventive Treatment of Tuberculosis(SCRIPT-TB)
Tuberculosis (TB) remains the most important infectious disease in the world. Preventive treatment plays an important role in successful control of TB.
- Trial name
- TB (NCT03900858)
- Testing
- Isoniazid；Rifapentine
- Where
- China
- Volunteers
- 566 people
- Sponsor
- Huashan Hospital
Tuberculous Meningitis
Retrospective Real-word Study of Linezolid for the Treatment of Tuberculous Meningitis
Tuberculous meningitis (TBM) is the most serious form of Mycobacterium tuberculosis infection, causing mortality and disability in more than half of the patients.
- Trial name
- NCT03898635
- Testing
- Linezolid
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Huashan Hospital
Hypertension, Hyperlipidemia
Hospital-level Variation in the Management of Blood Pressure and Low-density Lipoprotein in the Outpatient Hypertensives in China-a Cross Sectional Study
To investigate the proportion, medication use and control rate of metabolic abnormalities such as dyslipidemia in outpatients with hypertension in different levels of hospitals in China.
- Trial name
- NCT03862183
- Testing
- continuing medical education program
- Where
- China
- Volunteers
- 21,000 people
- Sponsor
- Huashan Hospital
Anemia, Iron-Deficiency
the Efficacy and Safety of Vitamin C for Iron Supplementation in Adult IDA Patients
IDA patients ofen receive ferrous succinate treatment to speed up the recovery of anemia, the doctor will prescribe ferrous succinate with or without vitamin C according to their own preferences.
- Trial name
- NCT02631668
- Testing
- ferrous succinate and vitamin C, ferrous succinate
- Where
- China
- Volunteers
- 440 people
- Sponsor
- Huashan Hospital
Astrocytoma, Oligodendroglioma
A Prospective Cohort to Study the Effect of Temozolomide on IDH Mutational Low Grade Gliomas
Low grade gliomas (LGGs) are the most common primary central nervous system malignancies. Brain surgeries with the most possible extent of resection are endeavored to achieve longer survivals in LGG patients.
- Conditions
- Astrocytoma, Oligodendroglioma, Oligoastrocytoma
- Trial name
- NCT02209428
- Testing
- Temozolomide
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Huashan Hospital
Parkinson Disease
A Pilot Study to Evaluate the Severity of Motor Dysfunction in Parkinson's Disease Based on AI Video Analysis
This study is a pilot study, mainly to explore the potential application value of specific pattern movement after video-based quantitative methods in the early recognition and assessment of Parkinson's disease.
- Trial name
- NCT03655171
- Testing
- Video-based quantitative methods
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Huashan Hospital
Glioma
Awake Intraoperative Language Mapping and Chinese Probabilistic Map Construction
The study aims at constructing a Chinese language probabilistic map by awake intraoperative direct electrical stimulation (DES) language mapping.
- Trial name
- NCT03641391
- Testing
- Intraoperative direct cortical electrical stimulation, Intraoperative direct subcortical electrical stimulation
- Where
- 3 sites in China
- Volunteers
- 300 people
- Sponsor
- Huashan Hospital
Gut Microbiota, Glioblastoma Multiforme, Microglia, Tumor Related Macrophagocyte, Prognosis
Gut Microbiota and Glioblastoma Multiforme Prognosis
Glioma is the most common primary cancer of the central nervous system, and around 50% of patients present with the most aggressive form of the disease, glioblastoma.
- Trial name
- NCT03631823
- Testing
- Chemotherapy with temozolomide or no chemotherapy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
Glioblastoma
Bevacizumab and Nimustine in Patients With Recurrent High Grade Glioma
The purpose of this study is to determine whether bevacizumab and nimustine are effective in the treatment of recurrent high grade glioma and to explore whether there is any subgroup being sensitive to this therapeutic protocol.
- Trial name
- NCT02698280
- Testing
- Bevacizumab, Nimustine
- Where
- China
- Volunteers
- 23 people
- Sponsor
- Huashan Hospital
Multidrug Resistant Tuberculosis
NGS-Guided(G) Regimens(R) of Anti-tuberculosis(A) Drugs for the Control(C) and Eradication(E) of MDR-TB
Tuberculosis (TB) has been one of the top 10 causes of death worldwide from a single infectious agent, ranking above HIV/AIDS. Management and eradication of this disease is being hindered by the emergence of multidrug-resistant…
- Trial name
- GRACE-TB (NCT03604848)
- Testing
- WHO-approved MDR-TB regimen, NGS-guided regimen: Regimen A, NGS-guided regimen: Regimen B
- Where
- 12 sites in China
- Volunteers
- 488 people
- Sponsor
- Huashan Hospital