Clinical trials: sponsored by Huashan Hospital
Cirrhosis, Varices
Baveno VI Criteria in Dynamic Monitoring of High-risk Varices in Compensated Cirrhotic Patients
Patients meet Baveno VI criteria (with a liver stiffness <20kPa and with a platelet count >150,000 are considered to have very low risk of having varices requiring treatment, but whether these patients can be followed up by…
- Conditions
- Cirrhosis, Varices, Non-invasive Evaluation
- Trial name
- CHESS2204 (NCT05538546)
- Testing
- Complete blood count, Transient elastrography, Endoscopy
- Volunteers
- 1,000 people
- Sponsor
- Huashan Hospital
COVID-19, Vaccine Reaction
A Real-world Study to Evaluate the Safety and Immunogenicity of a Third-dose Booster After Two Doses of an Inactivated COVID-19 Vaccine
This project is a prospective observational real-world study, recruiting and screening subjects who have completed 2 doses of the COVID-19 vaccine for more than 6 months and receive the third dose of the vaccine voluntarily into…
- Trial name
- NCT05493917
- Testing
- an inactivated SARS-CoV-2 vaccine named BBIBP-CorV
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
COVID-19
A Real World Study of Paxlovid for the Treatment of Hospitalized Patients Confirmed With COVID-19
The study was designed to analyze the efficacy and safety of Paxlovid for the treatment of COVID-19.
- Trial name
- NCT05387369
- Testing
- Paxlovid
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Huashan Hospital
AD, DM
The Mechanism Study of Diabetic Pancreatic Amyloid Deposition on Cognitive Dysfunction in Alzheimer's Disease
Alzheimer's disease (AD) is closely related to diabetes (DM). DM will aggravate the progression of AD, but the specific mechanism has not yet been clarified.
- Conditions
- AD, DM, PET-CT
- Trial name
- NCT05372458
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
Acute Respiratory Infection, Severe Pneumonia
Early Identification and Severity Prediction of Acute Respiratory Infectious Disease
Early identification and Severity prediction of Acute Respiratory infectious disease has become a top priority for clinicians at department of infectious and respiratory diseases after COVID-19 broke out.
- Conditions
- Acute Respiratory Infection, Severe Pneumonia, Next Generation Sequencing, Multiplex PCR
- Trial name
- ESAR (NCT04955756)
- Testing
- mNGS, Multiplex PCR
- Where
- 3 sites in China
- Volunteers
- 440 people
- Sponsor
- Huashan Hospital
Infertility, Female, Genital Tuberculoses, Female
The Prevalence and Reproductive Outcome of Infertile Women With Genital Tuberculosis
Female genital tuberculosis infection (FGTB) is an important cause of female infertility in TB-endemic areas. The pregnancy rate of assisted reproductive treatment (ART) in the infertile women with FGTB is still unsatisfied even…
- Trial name
- TB-PRIME (NCT05311423)
- Testing
- QuantiFERON-TB test & endometrial pathology & endometrial tissue GeneXpert Ultra
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Huashan Hospital
Stroke
CHinese Acute Tissue-Based Imaging Selection for Lysis In Stroke -Tenecteplase
To select the best dosage of tenecteplase for acute ischemic stroke patients (onset time 4.5-24h) of large vessel occlusion using early combined CT/MR imaging outcomes
- Trial name
- CHABLIS-T (NCT04086147)
- Testing
- Low dose tenecteplase, High dose tenecteplase
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Huashan Hospital
CNS Tumor, Neuropathology
Artificial Intelligence Neuropathologist
CNS tumor requires biopsy for pathological diagnosis, which is known as the "golden standard". We would like to achieve automated classification of brain tumors based on deep learning in digital histopathology images and…
- Trial name
- NCT05300113
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Huashan Hospital
COVID-19
Reactogenicity and Immunogenicity of Third Dose Vaccine Booster Following Two Doses of Inactivated Vaccines
It is a prospective open-labeled study, We intended to recruit the participants who completed 2 doses of inactivated COVID-19 vaccine 4-8 months before, and volunteered to receive the third dose of vaccine (inactivated vaccine…
- Trial name
- NCT05095298
- Testing
- Vaccine, COVID19
- Where
- 2 sites in China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
COVID-19, Vaccine Reaction
Safety and Immunogenicity of COVID-19 Vaccine Booster in Patients With Liver Diseases
Previous studies should that patients with chronic liver diseases, cirrhosis, hepatocellular carcinoma and post-liver-trasplant status had lower immunological response to SARS-CoV-2 vaccines than healthy population.
- Conditions
- COVID-19, Vaccine Reaction, Liver Diseases
- Trial name
- NMCIDCHESS2201 (NCT05204602)
- Where
- 19 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Huashan Hospital
Hypogonadotropic Hypogonadism
Efficacy of Prolonged GnRH Test in Male Adolescents With Postoperative HH
The Hypogonadotropic Hypogonadism(HH) could be caused by sellar lesions, sellar surgery or sellar radiotherapy. The incidence of HH after sellar surgery was higher in men than in women, and the therapy of HH was insufficient.
- Trial name
- NCT05184374
- Testing
- Gonadorelin
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Huashan Hospital
Recurrent Glioblastoma
Neoadjuvant PD-1 Antibody Alone or Combined With DC Vaccines for Recurrent Glioblastoma
Glioblastoma multiforme (GBM) are the most prevalent malignant tumor in central nervous system. At recurrence, no clear standard-of-care therapy is agreed for recurrent GBM (rGBM) and median overall survival is estimated to…
- Trial name
- NCT04888611
- Testing
- Camrelizumab plus GSC-DCV
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Huashan Hospital
Hepatocellular Carcinoma
Safety and Efficacy of Autoimmune Cell Therapy for Patients With Hepatocellular Carcinoma
In this study, safety and effects of IPM001 vaccine on human hepatocellular carcinoma are going to be investigated, IPM001 is a neoantigen/tumor-specific antigen sensitized autoimmune cell injection
- Trial name
- NCT05105815
- Testing
- IPM001
- Where
- China
- Volunteers
- 23 people
- Sponsor
- Huashan Hospital
Glioma
iMRI Guided Resection in Cerebral Glioma Surgery
Many clinical studies have been reported on iMRI, however, their evidence levels are relatively not as good as what people hope they will be.
- Trial name
- NCT01479686
- Testing
- iMRI, conventional neuronavigation
- Where
- China
- Volunteers
- 321 people
- Sponsor
- Huashan Hospital
Lipoprotein Disorder
A Multi-center, Prospective, Observational Study to Describe the siTuation of Blood Lipid mAnagement Among the Population With hypeRtension and/or Type 2 diabeTes in Community Health Center
A multi-center, prospective, observational Study to describe the siTuation of blood lipid mAnagement among the population with hypeRtension and/or type 2 diabeTes in Community Health Center
- Trial name
- NCT05081440
- Volunteers
- 5,000 people
- Sponsor
- Huashan Hospital
Enhanced Recovery After Surgery, Gastrointestinal Cancer
Study on the Efficacy and Safety of Enhanced Recovery After Surgery （ERAS）in Gastrointestinal Cancer
At present, there are more and more reports about enhanced recovery after surgery（ERAS）in China, but there is no ERAS treatment standard for gastrointestinal cancer, and there are many factors limiting the development of ERAS.
- Trial name
- NCT04201730
- Testing
- Enhanced Recovery After Surgery （ERAS）
- Where
- China
- Volunteers
- 356 people
- Sponsor
- Huashan Hospital
Rectal Cancer
Effectiveness and Safety Study on Different Timing of Preventive Ileostomy Closure After Surgery for Rectal Cancer
The purpose of this study is to evaluate the appropriate timing to do preventive ileostomy closure after total mesorectal excision of rectal cancer.
- Trial name
- NCT02665026
- Testing
- stoma closure at different times
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Huashan Hospital
Stroke, Ischemic
Thrombolysis Combined With Edaravone Dexborneol on Hemorrhagic Transformation for Acute Ischemic Stroke
To explore the safety and efficacy of edaravone dexborneol for the treatment of acute ischemic stroke patients who received thrombolysis.
- Trial name
- NCT05035953
- Testing
- Edaravone Dexborneol
- Volunteers
- 200 people
- Sponsor
- Huashan Hospital
Glioblastoma Multiforme
Adoptive Cell Therapy of Autologous TIL and PD1-TIL Cells for Patients With Glioblastoma Multiforme
At present, the investigators want to evaluate safety and efficacy of cell therapy based on Tumor-infiltrating T Lymphocyte (TIL）in glioblastoma.
- Trial name
- NCT03347097
- Testing
- TIL, PD1-TIL
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Huashan Hospital
Ultrasound Therapy; Complications
Identification of Interscalene Brachial Plexus on Ultrasonography Using a Deep Neural Network
The purpose of the study is to develop and validate an algorithm based on deep neural networks (DNNs) to identify interscalene brachial plexus on ultrasonography automatically.
- Trial name
- IBRUNNET (NCT04183972)
- Testing
- ultrasound examination
- Where
- China
- Volunteers
- 1,126 people
- Sponsor
- Huashan Hospital