Clinical trials: sponsored by Indiana University
Insomnia, Chronic Pain
TRAIN Your Sleep; Treating Adolescent Insomnia With Cognitive Behavioral Therapy for Insomnia (CBT-I)
The primary aim of this study is to understand how insomnia contributes to chronic pain in youth. Specifically, the investigators are interested in how insomnia and the treatment of insomnia impact emotional states and the body's…
- Trial name
- NCT04920630
- Testing
- Cognitive Behavioral Therapy - Insomnia (CBT-I)
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Indiana University
Colorectal Neoplasms
Gluteal Squeeze for Left Colon Distension
Good distension of the colon during colonoscopy is essential to detect polyps. Gas sometimes escapes the colon through the anus resulting in compromised distension.
- Trial name
- NCT04827485
- Testing
- Gluteal squeeze, No squeeze
- Where
- 2 sites in United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Indiana University
NAFLD, NASH - Nonalcoholic Steatohepatitis
Quantitative Ultrasound With Liver Incytes for Evaluation of Non-Alcoholic Fatty Liver Disease
The purpose of this study is to prospectively evaluate the utility of Liver Incytes in assessing NAFLD with or without advanced fibrosis in patients seen in liver clinics for suspected NAFLD diagnosis.
- Trial name
- NCT04576923
- Testing
- Velacur by Sonic Incytes
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Indiana University
FPP, Fermented Papaya Preparation
Nutritional Regulation of Leukocyte Function
The objective of the current study is to determine the dose at which Fermented Papaya Preparation ( FPP) is able to improve inducible respiratory burst outcomes in peripheral blood mononuclear cells (PBMC) and neutrophils of…
- Conditions
- FPP, Fermented Papaya Preparation, Supplements, Diabetic Wound
- Trial name
- FPP Supplement (NCT05191758)
- Testing
- FPP supplement
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Indiana University
Triple Negative Breast Cancer
Discerning the Impact of ctDNA Detection on Patient Decision Making in Early Stage Breast Cancer: a Conjoint Analysis
This study will examine how ctDNA and additional prognostic genomic information in patients with early stage breast cancer might influences patient decision- making regarding systemic therapy options.
- Trial name
- NCT05730010
- Where
- United States
- Volunteers
- 289 people
- Sponsor
- Indiana University
Solid Tumor, Exercise
Assessing Exercise Behavior and Preferences Among Patients and Oncologists
The purpose of this study is to understand the preferences and barriers surrounding exercise of both the patients and oncologists within Indiana University Simon Cancer Center.
- Trial name
- NCT04047589
- Testing
- Survey regarding exercise habits, barriers to exercise, and experience with exercise services from the cancer center., Survey regarding personal exercise habits and beliefs, barriers to making exercise recommendations
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Indiana University
Schizophrenia
Interactions of Fronto-Parietal High Frequency rTMS on Anterior Cingulate Cortex Activation in Schizophrenia
This will be a single site pilot study. 20 subjects with EPP (Early Phase Psychosis), defined as medical record documentation of the onset of clinically significant psychotic symptoms within the past 10 years, will be enrolled.
- Trial name
- rTMS-FPCC (NCT04309370)
- Testing
- 20 Hz rTMS
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- Indiana University
Schizophrenia
rTMS as a Probe of Episodic Memory Neurocircuitry in Schizophrenia
This will be a single site pilot study. 30 subjects with Early Phase Psychosis (EPP), defined as medical record documentation of the onset of clinically significant psychotic symptoms within the past ten years, will be enrolled.
- Trial name
- rTMS-EM (NCT04182113)
- Testing
- 1 Hz rTMS Stimulation
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Indiana University
Mild Cognitive Impairment
DIGITAL Biomarker: Blood Based Biomarkers in the Primary Care Setting for Alzheimer's Disease
The primary objective of this study is to evaluate the feasibility of implementing blood-based biomarker testing for amyloid positivity designed to aid the early detection of Alzheimer's Disease and Related Dementia (ADRD) in…
- Trial name
- DIGITAL (NCT05844488)
- Testing
- PrecivityAD
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Indiana University
NAFLD, NASH - Nonalcoholic Steatohepatitis
Vitamin E for NASH Treatment in HIV Infected Individuals
The purpose of this study is to see how taking Vitamin E daily affects fatty liver in persons living with HIV. Subjects will have both HIV and a fatty liver and the purpose of the study is to learn if underlying liver condition…
- Conditions
- NAFLD, NASH - Nonalcoholic Steatohepatitis, HIV Infections
- Trial name
- NCT03669133
- Testing
- Vitamin E
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- Indiana University
Anxiety Acute, Chronic Pain
Canine-Assisted ANxiety Reduction IN Emergency Care IV
Prior literature demonstrates that human stress can be reduced with exposure to animals. This study challenges current dogma by introducing a widely available, low cost method of dog therapy to reduce patient and provider stress.
- Trial name
- CANINE IV (NCT04287452)
- Testing
- Control, Dog Therapy
- Where
- United States
- Sponsor
- Indiana University
Anemia
ORthopaedic Trauma Anemia With Conservative Versus Liberal Transfusion
The purpose of this study is to determine if there is a difference in outcomes between liberal transfusion (transfusing when hemoglobin drops below a set higher value number) and conservative transfusion (transfusing when…
- Trial name
- ORACL (NCT02972593)
- Testing
- Blood and blood products for transfusion
- Volunteers
- 161 people
- Sponsor
- Indiana University
Conduct Disorder, Child
Virtual Reality to Improve Social Perspective Taking
This project will examine how virtual reality treatment that provides users with the alternate perspective of a virtual interpersonal interaction impacts psychological and neurobiological markers of social perspective taking in…
- Conditions
- Conduct Disorder, Child, Adolescent, Attention Deficit and Disruptive Behavior Disorders
- Trial name
- NCT03927612
- Testing
- Virtual reality perspective taking training, Virtual reality control perspective
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Indiana University
Nephrectomy
Comparing 3 Different Types of Pain Blocks After Laparoscopic Nephrectomy
All three methods of postoperative analgesia have been shown to decrease postoperative pain control in nephrectomy patients, the three methods have never been compared to each other.
- Trial name
- NCT03581539
- Testing
- Transverses Abdominis Plane (TAP) block, Quadratus Lumborum (QL) block, Surgeon Infiltration using Exparel
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Indiana University
Post-ERCP Acute Pancreatitis
Urine Trypsinogen 2 Dipstick for the Early Detection of Post-ERCP Pancreatitis
Post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) is the most common, serious complication of ERCP. More than 500,000 ERCP procedures are performed from which 25,000 cases of PEP occur in the U.S.A.
- Trial name
- NCT03098082
- Testing
- Actim Pancreatitis
- Where
- United States
- Volunteers
- 394 people
- Sponsor
- Indiana University
Relapsed Germ Cell Cancer, Cisplatin Induced Tinnitus
Music Therapy For The Treatment Of Cisplatin Induced Tinnitus In Patients With rGCC: A Pilot Study
Pilot study evaluating the feasibility of recruitment, retention, and compliance to a modified Heidelberg Model of Neuro-Music Therapy (mHNMT) in patients with Cisplatin-induced Tinnitus and relapsed Germ Cell Cancer (rGCC).
- Trial name
- NCT04402593
- Testing
- Modified Heidelberg Model of Neuro-Music Therapy
- Where
- United States
- Sponsor
- Indiana University
Opioid Use, Post-thoracotomy Pain Syndrome
Serratus Anterior Plane Block for Management of Post Thoracotomy Pain
This is a single-center, randomized, prospective study evaluating the effect of serratus anterior plane block performed after induction of anesthesia, but before the start of surgery on postoperative opioid requirements.
- Conditions
- Opioid Use, Post-thoracotomy Pain Syndrome, Local Anaesthetic Agent Overdose, Local Anesthetic Complication
- Trial name
- SAPB (NCT04258436)
- Testing
- Serratus anterior block
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Indiana University
Depression
Standardized Versus Tailored Implementation of Measurement Based Care for Depression
Depression remains among the nation's top 10 chronic illnesses, costing over $80 billion annually; however, Measurement Based Care (MBC) is a relatively simple evidence-based intervention framework that has been shown to improve…
- Trial name
- iMBC (NCT02266134)
- Testing
- Tailored Implementation of Measurement Based Care, Standard Implementation of Measurement Based Care
- Where
- 6 sites in United States
- Volunteers
- 382 people
- Sponsor
- Indiana University
Childhood Obesity
A Theory Driven, Rurally Tailored, Family-Based, Telehealth Intervention for Childhood Obesity
This pilot trial aims to improve the lives of individuals in rural Indiana by addressing the leading cause of death, obesity. The purpose is to help children and their families develop healthy behaviors to decrease childhood…
- Trial name
- NCT04720703
- Testing
- Newsletters, Family-based Telehealth Intervention
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Indiana University
Pregnancy, High Risk
Coconut Oil vs. Commercial Ultrasound Gel In Obstetric Ultrasounds
The goal of this randomized controlled trial is to compare the use of coconut oil with commercial ultrasound gel for obstetrical ultrasounds. The main questions it aims to answer are: 1.
- Trial name
- NCT05653362
- Testing
- Coconut Oil, Commercial Ultrasound Gel
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Indiana University
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