Clinical trials: sponsored by Indiana University
Type 1 Diabetes
Long Term Effects of Diabetes of Very Young Children
To investigate neurocognitive and behavioral measures in 25 children aged 6-10 years diagnosed with diabetes for > 5 years who have received long-term insulin pump therapy (> 3 years) compared to a group of children matched for…
- Trial name
- NCT00707629
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Indiana University
Pancreas Neoplasms
Use of Celecoxib in Patients With Intraductal Papillary Mucinous Neoplasms (IPMNs)
The purpose of the study is to find out whether the drug celecoxib has beneficial effects on people with pre-cancerous lesions of the pancreas.
- Trial name
- NCT00198081
- Testing
- COX-2 Inhibitor 6-8 weeks prior to surgery, COX-2 Inhibitor for 6 months prior to follow-up EUS or ERCP
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Indiana University
Pancreatic Cancer, Adenocarcinoma of the Pancreas
Phase I Study of Gemcitabine, Sorafenib and Radiotherapy in Patients With Unresectable Pancreatic Cancer
The purpose of this study is to evaluate the safety and tolerability of the combined treatment of Sorafenib (BAY 43-9006) with Gemcitabine and radiotherapy in patients with localized unresectable pancreatic cancer.
- Trial name
- NCT00375310
- Testing
- Gemcitabine, Sorafenib, Radiotherapy
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Indiana University
Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia
Basiliximab #2: In-Vivo Activated T-Cell Depletion to Prevent Graft-Versus_Host Disease (GVHD) After Nonmyeloablative Allotransplantation for the Treatment of Blood Cancer
The purpose of this study is to compare the effects (good and bad) of the medication basiliximab in combination with cyclosporine (investigational therapy) for the prevention of a complication of bone marrow transplantation known…
- Conditions
- Acute Myelogenous Leukemia, Acute Lymphocytic Leukemia, Chronic Myelogenous Leukemia, Chronic Lymphocytic Leukemia
- Trial name
- NCT00975975
- Testing
- Basiliximab
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Indiana University
Infection Prevention
Study of Catheter-related Infections Using Antibiotic-coated Versus Conventional Catheters in Children
The primary purpose of the study is to determine if a therapeutic difference exists between central venous catheters impregnated with minocycline and rifampin and conventional catheters not impregnated with antibiotics when used…
- Trial name
- NCT00370149
- Testing
- Antibiotic-impregnated Catheters (M/R), Non-impregnated Catheters (C/S)
- Where
- United States
- Volunteers
- 326 people
- Sponsor
- Indiana University
Gallbladder Cancer, Cholangiocarcinoma
Storage of Bile From Routine Procedures to Study Risk Factors
The purpose of the study is to establish a repository of human bile as a resource for studies evaluating molecular predictors of biliary cancer risk.
- Conditions
- Gallbladder Cancer, Cholangiocarcinoma, Biliary Tract Cancer
- Trial name
- NCT00414843
- Where
- United States
- Volunteers
- 390 people
- Sponsor
- Indiana University
Insertional Achilles Tendinopathy
Eccentric Exercise Versus Eccentric Exercise and Astym for Insertional Achilles Tendinopathy
The purpose of this research study is to determine if Astym® treatment is an effective treatment for patients with Achilles pain.
- Trial name
- NCT01988155
- Testing
- Eccentric Exercise, Astym
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Indiana University Health Ball Memorial Hospital Rehabiliation Services
Morbid Obesity
Study to Determine Effective Dosing of Fondaparinux in Obese Persons
This is a prospective open-label study comparing two dosing regimens of fondaparinux, which is used to prevent deep vein thrombosis, in morbidly obese volunteers.
- Trial name
- NCT00346879
- Testing
- fondaparinux
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Indiana University
Type 2 Diabetes Mellitus, Healthy
Modulation of Human Myocardial Metabolism by GLP-1 Dose Response
The objective of this proposal is to provide quantitative dose-response data for effects of GLP-1 on myocardial glucose uptake in healthy control subjects and obese type 2 diabetic subjects, in support of the design of later…
- Trial name
- NCT01607450
- Testing
- GLP-1 Low Dose, GLP-1 Mid-Range Dose, GLP-1 High Dose
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Indiana University
Asthma
Assessment Of The Effects Of Short and Long Term Use Of CPAP
We hypothesize that the nocturnal use of continuous positive airway pressure in adults and children with asthma will decrease airway reactivity.
- Trial name
- NCT00592631
- Testing
- CPAP-Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Indiana University
HIV, Endothelial Dysfunction
N-acetylcysteine to Reduce Oxidative Stress and Improve Endothelial Function in HIV-infected Older Adults
The goal of this study is to determine if n-acetylcysteine, given as PharmaNAC, reduces oxidative stress and improves vascular function in HIV-infected older adults already on HIV treatment.
- Conditions
- HIV, Endothelial Dysfunction, Oxidative Stress
- Trial name
- NCT01962961
- Testing
- PharmaNAC (N-acetylcysteine)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Indiana University
Attention Deficit Hyperactivity Disorder
Using Computers to Assist in the Diagnosis and Treatment of Attention-deficit/Hyperactivity Disorder (ADHD)
Attention-deficit/hyperactivity disorder (ADHD) is the most commonly diagnosed behavioral disorder in children. Prevalence rates in the United States range from 2% to 18% depending on diagnostic criteria and population studied.
- Trial name
- NCT01351064
- Testing
- CHICA ADHD Module
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Indiana University
Panic Disorder
A Study of Quetiapine SR (Seroquel SR) to Treat SSRI-Resistant, Comorbid Panic Disorder Patients
The primary objective of this study is to test the hypothesis that a SSRI plus quetiapine SR (Seroquel SR) will result in superior early (first 1-3 weeks of treatment) stabilization of panic symptoms in SSRI-resistant, comorbid…
- Trial name
- NCT00619892
- Testing
- quetiapine XR
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Indiana University
Hemodialysis, Hypertension
Hypertension in Hemodialysis Patients (Aim 3)
We will directly test the hypothesis that an initial strategy of lisinopril-based therapy will be more effective than atenolol-based therapy in causing regression of left ventricular hypertrophy (LVH) over one year in patients…
- Conditions
- Hemodialysis, Hypertension, Left Ventricular Hypertrophy
- Trial name
- NCT00582114
- Testing
- Lisinopril, Atenolol
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Indiana University
Exercise-Induced Bronchospasm
Effects of Montelukast on Occult Exercise-Induced Bronchospasm in Athletes
The purpose of this study is to determine if treatment of exercise-induced Bronchospasm with montelukast will help college athletes train more effectively and thus become more competitive in a non ergogenic manner.
- Trial name
- NCT00375232
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Indiana University
Cardiovascular Diseases, Heart Diseases
Salt Sensitivity, Cardiovascular and Metabolic Disease
To identify the role of salt-sensitivity of blood pressure in the pathogenesis of hypertension.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension, Angina Pectoris
- Trial name
- NCT00005489
- Sponsor
- Indiana University
Severe Mental Illness
Illness Management and Recovery Treatment Integrity Scale Validation and Leadership Intervention Development
Illness Management and Recovery (IMR) is an evidenced-based approach to teaching consumers with severe mental illness how to set and achieve personal recovery goals and acquire the knowledge and skills to independently manage…
- Trial name
- IT IS VALID (NCT02431299)
- Volunteers
- 299 people
- Sponsor
- Indiana University
Colonic Motility Index, Constipation
Effect of Octreotide on the Colonic Motility in Pediatric Patients
The research study is designed to test how a medication called octreotide affects the motility (contraction or squeezing) of the colon (large intestine).
- Trial name
- NCT01917773
- Testing
- Octreotide, Bisacodyl
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Indiana University
Major Depressive Disorder, Depression
Anti-INFLammatory to Address Mood and Endothelial Dysfunction (INFLAMED)
The objective of this clinical trial is to evaluate whether an anti-inflammatory medication, pentoxifylline, reduces depressive symptoms and improves artery function.
- Conditions
- Major Depressive Disorder, Depression, Depressive Symptoms, Cardiovascular Disease (CVD)
- Trial name
- INFLAMED (NCT01625845)
- Testing
- Pentoxifylline, Standard Treatment
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Indiana University
Breast Cancer, Cancer Survivor
Quality of Life in African-American or Caucasian Female Breast Cancer Survivors
RATIONALE: Studying quality of life in cancer survivors may help determine the long-term effects of breast cancer and may help improve the quality of life for future cancer survivors.
- Conditions
- Breast Cancer, Cancer Survivor, Depression, Fatigue
- Trial name
- NCT00268502
- Testing
- study of socioeconomic and demographic variables, fatigue assessment and management, management of therapy complications
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- Indiana University
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