Clinical trials: sponsored by Institut Pasteur
HIV Infection, Hepatitis C Infection
Evaluation of HCV Care and Treatment for HIV-HCV Co-infected Patients in Decentralised Areas in Vietnam
With the advent of direct acting antiviral (DAA) treatment in 2013, HCV elimination has become feasible. Still, achieving HCV elimination in resource-limited countries appears to be arduous as several challenges need to be…
- Trial name
- MOVIDA-Hep2 (NCT05506475)
- Testing
- Blood samples
- Where
- 2 sites in Vietnam
- Volunteers
- 400 people
- Sponsor
- Institut Pasteur
HIV Infections
MOVIDA 1 Ter - Evaluation of the Cobas® Plasma Separation Card in the Field in Vietnam
In low- and middle-income countries, viral load (VL) monitoring of patients living with HIV and followed on antiretroviral therapy (ART) in remote settings is still scarce.
- Trial name
- MOVIDA1-Ter (NCT04794725)
- Testing
- Blood sampling
- Where
- 2 sites in Vietnam
- Volunteers
- 250 people
- Sponsor
- Institut Pasteur
Monkeypox Virus Infection
A One Health Study of Monkeypox Human Infection
This multidisciplinary project aim to understand the epidemiology of the monkeypox in Central African Republic through the identification of the animal reservoir, the clinical and epidemiological description of the human…
- Trial name
- AFRIPOX (NCT05058898)
- Testing
- blood samples, Scabs and pus samples
- Where
- Central African Republic
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Hepatitis B
Neovac 2 Burkina Faso: Impact of the Integration of Hepatitis B Birth Dose Vaccine Into the Infant Immunization Schedule
Hepatitis B virus (HBV) infection is an important global health problem, and the WHO adopted a strategy to eliminate HBV infection as a public health threat by the year 2030.
- Trial name
- NEOVAC2BK (NCT04029454)
- Testing
- birth dose vaccination against hepatitis B strategy
- Where
- 2 sites in Burkina Faso
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Monkey Pox
Clinical and Biological Aspects of the MONKEYPOX Disease
Monkey pox virus (MPXV), of the genus Orthopoxvirus, regularly causes epidemics in endemic areas of central and western Africa. Since January 1, 2022, cases of Monkey pox have been reported to WHO by 96 Member States in the 6 WHO…
- Trial name
- PoxVac22 (NCT05627713)
- Testing
- Blood sample collection, urine sample collection
- Where
- France
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Bipolar Disorder
Toi Même: a Mobile System for Measuring Bipolar Illness
Bipolar disorder is a severe psychiatric illness with chronic course and it is associated with high risk of relapse and hospitalisation, and many patients do not recover to their previous psychosocial functioning.
- Trial name
- NCT03508427
- Testing
- Daily self-monitoring
- Where
- 3 sites in France
- Volunteers
- 36 people
- Sponsor
- Institut Pasteur
Tuberculosis
Dried Blood Spot Test to Assess TB in Pregnancy
Despite being a key contributor to maternal mortality in high-burden regions, TB in pregnancy is a hugely neglected area of global public health.
- Trial name
- DROPTB2 (NCT04871230)
- Testing
- 3G DBS, Sputum Test, 3G Veinous Blood
- Where
- 12 sites in Madagascar
- Volunteers
- 1,424 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur de Madagascar
SARS (Severe Acute Respiratory Syndrome), COVID-19
Sero-epidemiological Study of the SARS-CoV-2 Virus Responsible for COVID-19 in France
On January 2020, the discovery of a new coronavirus (SARS-CoV-2) was officially announced by the Chinese health authorities and the World Health Organization (WHO).
- Trial name
- CORSER (NCT04325646)
- Testing
- Human Biological samples
- Where
- 21 sites in France
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Infectious Disease, Tropical Disease
Collection of Human Biological Samples for the Development and Validation of New Methods of Diagnosis and for the Realization of Expertises Diagnostics in the Field of Infectious Diseases and Tropical
Direct constitution of collections from various samples taken on a prospective cohort of healthy volunteers, to prepare human biological samples of known characteristics (biochemical and serological in particular) and quality…
- Trial name
- Diagmicoll (NCT03912246)
- Testing
- biological samples, lumbar puncture
- Where
- 2 sites in France
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Healthy Subjects
Genetic & Environmental Determinants Of Immune Phenotype Variance: A Longitudinal Assessment
Effects of aging, genetics and environmental exposures on immune variation in a previously well-defined healthy population (NCT03905993).
- Trial name
- MI-V3 (NCT05381857)
- Testing
- Human Biological Samples
- Where
- France
- Volunteers
- 415 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
SARS (Severe Acute Respiratory Syndrome), Covid19
Longitudinal Follow-up of a Population Cohort in a French City With High SARS-CoV-2 Circulation, in Early 2020 [COVID-19]
An initial retrospective epidemiological investigation was conducted in a city north of France after the diagnosis of the first case of COVID-19 on February 2020.
- Trial name
- COVID-OISE (NCT04644159)
- Testing
- Human biological samples
- Where
- 2 sites in France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Covid19
Study of Socio-demographic Factors, Behaviors and Practices Associated With Infection With SARS-CoV-2 Responsible for COVID-19
The objective of the study is to identify socio-demographic factors, behaviors and practices associated with infection with SARS-CoV-2 to help determine where and how patients mostly get infected with SARS-CoV-2.
- Trial name
- ComCor (NCT04607941)
- Testing
- Questionnaires, Phone interviews
- Where
- 2 sites in France
- Volunteers
- 766,818 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Rabies
Immunity Persistence After Abridged Intradermal Rabies PEP
After exposure, rabies can be prevented in almost 100% of cases by the administration of sufficient and timely post-exposure prophylaxis (PEP).
- Trial name
- RESIST-3 (NCT04829630)
- Testing
- rabies vaccine
- Where
- 2 sites in Cambodia, Madagascar
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Rabies Post-exposure Prophylaxis
Immunogenicity Assessment of Subjects Receiving Rabies Post-exposure Prophylaxis in Cambodia
A rabies virus neutralizing antibody (RVNA) concentration ≥ 0.5 IU/ml at 14 days after immunization is considered a proxy for protection in vaccine efficacy studies.
- Trial name
- NCT05684185
- Testing
- Intramuscular (IM) rabies post-exposure prophylaxis, Intradermal (ID) rabies post-exposure prophylaxis
- Where
- Cambodia
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur du Cambodge
COVID-19
Immunogenicity of Heterologous Versus Homologous Prime Boost Schedule With mRNA and Inactivated COVID-19 Vaccines
This study is a randomized, simple-blinded comparative phase III clinical trial comparing the immunogenicity of two doses Coronovac to that of a first dose of Coronovac (Sinovac, Beijing, China) followed by a booster shot with…
- Trial name
- NCT05668065
- Testing
- CoronaVac/CoronaVac, CoronaVac/BNT162b2
- Where
- 5 sites in Tunisia
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur de Tunis
Obesity
Food Supplement Effect on Overweight or Moderate Obesity
The aim of this study is to assess the effect of a food supplement containing extracts of carrot and rose hip seeds on the weight of volunteers with overweight or moderate obesity.
- Trial name
- PHYTOENIX (NCT05178667)
- Testing
- High dose, Low dose, Maltodextrin
- Where
- 2 sites in France
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur de Lille
Burn Out, Psychological Disturbance
A Specialized Nutraceutical for Pre-burnout
High demands, professional overload and emotional stress are well known negative influences on mental health. Chronic stress-related occupational diseases, especially Burnout, are becoming an important issue.
- Trial name
- WELBI (NCT04532892)
- Testing
- Meta 18.06 Day and Meta 18.06 Night
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur de Lille
Assess the Effect of an IR Reflexotherapy on Overweight and Class I Obese People
Interest in the Medium Term of an Infrared Reflexotherapy on Overweight or Class I Obese People
The study aim is to Assess the Effect of an IR Reflexotherapy on Overweight and Class I Obese People.
- Trial name
- REFLEX-IR (NCT02000037)
- Testing
- IR Reflexotherapy, Dietary care
- Where
- France
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur de Lille
Child Development
Effect of Infant Formula Intake on Infant Growth From 0 to 6 Months.
From birth to 5 months, milk is the essential and unique food of the newborn. The French National Nutrition Program (PNNS) recommends exclusive breastfeeding "up to 6 months and at least 4 months for a healthy benefit".
- Trial name
- BABYMILK (NCT02997826)
- Testing
- Infantil formula
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur de Lille
Shift-work, Eating Behavior
Assesment of the Impact of a Nutritional Prevention Programme for Employees in Staggered Hours.
Staggered work affects about 20% of French employees and its health risks are now well known. They concern physical health (sleep disorders, weight gain, cancer, cardiovascular disorders, nutritional problems, etc.) and…
- Trial name
- PREV'HODE (NCT03203135)
- Testing
- Nutritional prevention programme
- Where
- France
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur de Lille