Clinical trials: sponsored by Istanbul University
Postoperative Delirium
Comparison of DRS-R-98 and 3D-CAM in the Assessment of Postoperative Delirium in Elderly Patients
Postoperative delirium (POD) is a transient and usually fully reversible altered state of consciousness that develops acutely or subacutely after surgery, characterized by widespread, daily fluctuations in brain metabolism and…
- Trial name
- NCT05992818
- Testing
- comparing DRS-R-98 (The Delirium Rating Scale--Revised-98) and 3D-CAM (3-minute diagnostic assessment for CAM-Confusion Assessment Method-defined delirium) tests to assess postoperative delirium
- Where
- Turkey (Türkiye)
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Autism With High Cognitive Abilities, COVID-19 Pandemic
The Impact of Covid-19 Pandemic On The Children With Autism Spectrum Disorder
The Covid-19 outbreak has caused families and individuals to change their life routines and eating habits, and has affected their psychology, especially for children with autism, due to the change in their routines.
- Trial name
- NCT05197634
- Testing
- Not Applicable (observation)
- Where
- Turkey (Türkiye)
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Regenerative Endodontic, Apexification
Comparison of Apexification and Regenerative Endodontic Therapy: a Retrospective Study
In this study, the effects of mineral trioxide aggregation (MTA) apexification and regenerative endodontic treatment (RET) methods on periapical healing was compared with fractal analysis (FD) and periapical index (PAI).
- Conditions
- Regenerative Endodontic, Apexification, Fractals
- Trial name
- NCT05213026
- Testing
- Regenerative endodontics
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Bariatric Surgery, Obesity
Online Clinic Pilates Exercises in Patients Undergoing Bariatric Surgery
Obesity is defined as abnormal or excessive fat accumulation that can impair health. Obesity is considered a risk factor for diseases such as hypertension, heart failure, coronary heart diseases, diabetes mellitus, sleep apnea…
- Conditions
- Bariatric Surgery, Obesity, Exercise, Physical Activity
- Trial name
- NCT05454696
- Testing
- Exercise, online physical activity counselling
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Istanbul University
Periodontitis
IL-6, IL-17 and IL-35 Levels in the Gingival Crevicular Fluid of Patients With Periodontitis and Healthy Controls
Periodontitis is an inflammatory disease characterized by periodontal tissue destruction caused by bacterial infection. The immune response plays an important role in the progression of periodontitis.
- Trial name
- NCT05306860
- Testing
- No intervention was applied to the groups the samples will be collected in terms of the diagnosis (periodontitis, healthy)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Plyometric Exercise, Proprioception
The Effect of Upper Extremity Plyometric Exercises on Proprioception, Time to Peak Torque and Performance in Young Female Basketball Players
Plyometric exercises are used in many sports branches to increase sportive performance and neuromuscular coordination. It is known that side values such as the time to reach peak torque next to muscle strength, which is one of…
- Conditions
- Plyometric Exercise, Proprioception, Upper Quarter y Balance Test, The Closed Kinetic Chain Upper Extremity Stability Test
- Trial name
- NCT05559216
- Testing
- Plyometric Training
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Peri-implant Mucositis, Peri-Implantitis
Chitosan Brushes vs Air-Abrasive Devices on Peri-implant Mucositis Treatment: A Randomized Clinical
Bleeding on probing (0,1,2,3), plaque index (+,-) and pocket probing depth will be recorded for each visit. Before the procedure, the patient will be randomly assigned to one of four groups and records will be kept.
- Conditions
- Peri-implant Mucositis, Peri-Implantitis, Bleeding on Probing, Periodontal Pocket
- Trial name
- NCT06287957
- Testing
- Labrida BioClean, EMS Handy 3.0 Perio Premium
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Adolescent Idiopathic Scoliosis
The Effects of Core Stability Training in Children With Adolescent Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) is a three-dimensional structural deformity of the spine in which lateral flexion and axial rotation are seen in vertebrae with a Cobb (method for measuring spinal curvature) angle of 10° and…
- Trial name
- NCT05056363
- Testing
- Home Based Traditional Scoliosis Exercises, Core Stability Training
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Istanbul University
Hemiplegia
The Effect of Virtual Reality-Mediated Rehabilitation in Ischemic Stroke Patients
The aim of the study was to investigate the effectiveness of virtual reality-mediated upper extremity rehabilitation added to the conventional rehabilitation program on upper extremity, quality of life, range of motion and…
- Trial name
- NCT05869786
- Testing
- Virtual Reality Mediated Upper Extremity Rehabilitation (SensoRehab®), conventional rehabilitation program, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Istanbul University
Femoral Neck Fractures, Femoral Neck Shortening
Mid-Term Radiological Outcomes of Femoral Neck Fractures Treated With Osteosynthesis: A Comparative Analysis
OBJECTIVES: This study assesses the efficacy of dynamic hip screw (DHS) versus cannulated screws for femoral neck fractures, focusing on femoral neck shortening, avascular necrosis (AVN) incidence, and functional outcomes.
- Trial name
- NCT06263309
- Testing
- Femoral neck shortening measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Istanbul University
Analgesia, Pain, Postoperative
Comparison of Local Anesthetic Dose in Ipack Block Performed in Knee Arthroplasty Operations
The investigators research was designed as a single-center, prospective, randomized study. The patients undergoing knee artrhroplasty surgery in Istanbul University Istanbul Medicine Faculty Department of Orthopedics and…
- Conditions
- Analgesia, Pain, Postoperative, Anesthesia
- Trial name
- NCT05963139
- Testing
- Bupivacaine, Morphine Sulfate
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Istanbul University
Distal Radius Fractures
CT Analysis Comparing Cast and Three-Point Indexes in Distal Radius Fracture Care
Objectives: To compare the cast index and three-point index measurements obtained using computed tomography (CT) with those acquired using conventional methods for treating distal radius fractures Design: A retrospective cohort…
- Trial name
- NCT06255106
- Testing
- cast treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 113 people
- Sponsor
- Istanbul University
Cerebral Palsy, Care Giving Burden
Caregiver Burden in Cerebral Palsy Undergoing Hip and Knee Surgery
The aim of this observational study was to obtain information about the change in the burden of care of parents of children with cerebral palsy after hip and knee surgeries.
- Trial name
- Caregiver CP (NCT06224322)
- Testing
- Assesment Scale
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Ozone Therapy, Exercise Performance
Effect of Ozone Therapy on Aerobic Exercise Performance
The goal of this clinical trial is to investigate the effect of the ozone therapy applied using the major autohemotherapy method on exercise performance in male healthy individuals.
- Trial name
- NCT06217549
- Testing
- ozone therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Patellar Tendinopathy
Diagnostic Value of Shear-Wave Elastography for Patellar Tendinopathy
To investigate the accuracy of shear-wave elastography (SWE) in diagnosing patellar tendinopathy in female volleyball and basketball players.
- Trial name
- NCT06199583
- Testing
- Shear-wave elastography
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Knee Osteoarthritis
Estimation of the MCID for Patients With Knee Osteoarthritis
Background: The effect of exercise on knee osteoarthritis (OA) is often evaluated with patient-reported scales. The Minimal Clinically Important Difference (MCID) values of these scales are needed to understand the change in…
- Trial name
- NCT06034665
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Istanbul University
Knee Osteoarthritis
Effects of Dextrose Prolotherapy in Patients With Knee Osteoarthritis
In this prospective, randomized, controlled, single-blinded study, we aimed to evaluate the effects of Dextrose Prolotherapy injections in patients with chronic knee osteoarthritis.
- Trial name
- NCT06063356
- Testing
- Intra-articular and extra-articular Dextrose Prolotherapy injection, Intra-articular and extra-articular Saline injection
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Istanbul University
Postoperative Complications, Procedure, Thoracic Surgical
Preoperative RESpiratory Training and MOBilization to Prevent Postoperative Pulmonary Complications in Patients Undergoing Thoracic Surgery
Postoperative pulmonary complications (PPCs) are the most frequent complications occurring in patients undergoing thoracic surgery and they are associated with prolonged hospital stay, decreased survival and expanding medical…
- Trial name
- RESMOB (NCT05416411)
- Testing
- Inspiratory muscle training
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 436 people
- Sponsor
- Istanbul University
Sepsis, Septic Shock
Evaluation of Candidate Biomarkers to Predict Disease Severity and Acute Kidney Injury in Sepsis Patients
Investigators predict that the information that can be obtained in terms of renal functions before clinical development in sepsis patients can be valuable in terms of guiding treatment algorithms, planning renal replacement…
- Conditions
- Sepsis, Septic Shock, Acute Kidney Injury
- Trial name
- NCT05310812
- Testing
- Biochemical evaluation.
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Istanbul University
COVID-19, Dentistry
COVID-19 and Working Conditions of Dentists
The aim of this study is to evaluate the protective measures and awareness of dentists working in Turkey regarding the COVID-19 pandemic.
- Trial name
- NCT05175820
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 1,008 people, healthy volunteers welcome
- Sponsor
- Istanbul University