Clinical trials: sponsored by Istanbul University
Early Mobilization, Open-heart Surgery, Virtual Reality
Exercises for Early Mobilization of Patients Undergoing Open Heart Surgery With Virtual Reality Application
This randomized controlled trial evaluated the effects of a virtual reality (VR)-assisted early mobilization exercise program in patients undergoing open-heart surgery.
- Trial name
- NCT06918600
- Testing
- Virtual Reality-Supported Early Mobilization Program
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Lipedema
Telerehabilitation-Supported Exercise in Women With Lipedema
This prospective, single-blind, randomized controlled trial aims to evaluate the effectiveness of a telerehabilitation-supported exercise program in women with lipedema.
- Trial name
- NCT07885241
- Testing
- Telerehabilitation-Supported Exercise, Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Istanbul University
Wound Healing, Alveolitis of Jaw
Effect of Curcumin Topical Spray on Wound Healing After Tooth Extraction
This randomized, single-blind, controlled clinical trial aims to evaluate the effects of a topical curcumin spray on post-extraction wound healing and postoperative symptoms in adults undergoing first molar extraction.
- Conditions
- Wound Healing, Alveolitis of Jaw, Tooth Extraction, Curcumin
- Trial name
- NCT07874789
- Testing
- Curcumin Topical Spray, Chlorhexidine Topical Spray
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Postoperative Period, Lung Cancer (Diagnosis)
Investigation of the Effects of Tele-Yoga Training in Individuals With Lung Cancer Undergoing Lung Resection Surgery
This randomized controlled clinical trial aims to evaluate the effects of an 8-week tele-yoga intervention in individuals with lung cancer who have undergone lung resection surgery.
- Trial name
- NCT07001670
- Testing
- Tele-Yoga Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University
Periodontal Disease, Periodontitis
Antibiotic Resistance Genes in Periodontitis
Antimicrobial resistance (AMR) is a major global public health concern, and the oral microbiome may serve as an important reservoir of antibiotic resistance genes (ARGs).
- Conditions
- Periodontal Disease, Periodontitis, Antibiotic Resistance Genes
- Trial name
- NCT07887204
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul University
PARKINSON DISEASE (Disorder)
Effectiveness of a Home-Based Exercise Program Supported by Self-Management Education in People With Parkinson Disease
This randomized, assessor-blinded clinical trial evaluates whether a structured self-management education and home exercise program improves balance, walking capacity, fall-related concerns, upper-extremity dexterity, and quality…
- Trial name
- NCT07817862
- Testing
- Self-Management Education and Home Exercise Program, Parkinson Disease Educational Booklet
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Istanbul University
Spinal Anesthesia-Induced Hypotension, Cerebral Oxygenation
Effects of Ondansetron Timing During Spinal Anesthesia for Urologic Surgery
This study will evaluate whether the timing of intravenous ondansetron administration affects cerebral oxygenation and hemodynamic stability in older adults undergoing endoscopic urologic surgery under spinal anesthesia.
- Trial name
- NCT07858149
- Testing
- Ondansetron 8 mg, 0.9 % sodium chloride
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people
- Sponsor
- Istanbul University
Pain, Postoperative
Glossopharyngeal Nerve Block in Pediatric Adenotonsillectomy Operations
Tonsilloadenoidectomy operations in pediatric patients cause local pain. Especially, in order to reduce the need for narcotic painkillers, to ensure patient compliance and well-being, and to provide better quality pain management…
- Trial name
- NCT07873307
- Testing
- Bupivacaine hydrogen chloride (HCl) %0.125 in 0,2 milliliter/kilogram (ml/kg)+ 0,2 milliliter/kilogram (ml/kg) injection, Bupivacaine hydrogen chloride (HCl) %0.25 in 0,2 milliliter/kilogram (ml/kg)+ 0,2 milliliter/kilogram (ml/kg) injection
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Istanbul University
Developmental Coordination Disorder (DCD)
Video-Assisted Core Stabilization Exercises in Children With Developmental Coordination Disorder
This single-center, single-blind, prospective randomized controlled trial aims to investigate the effects of a video-assisted core stabilization exercise program (Fun-Core) on motor competence, balance, and gait in children with…
- Trial name
- NCT07868263
- Testing
- Video-Assisted Fun-Core Exercise Program, Home-Based Core Stabilization Exercise Program
- Volunteers
- 22 people
- Sponsor
- Istanbul University
Frozen Shoulder
Comparison of the Effectiveness of Stretching and Strengthening Exercises in Patients With Frozen Shoulder
The aim of the study is to compare the effectiveness of stretching and strengthening exercises on pain, functional status, range of motion and psychosocial factors in patients with frozen shoulder.
- Trial name
- NCT06469502
- Testing
- Stretching Exercises, Strengthening Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Istanbul University
Zone 2 Flexor Tendon Injuries of the Hand
Investigation of Effectiveness of Telerehabilitation for Zone 2 Flexor Tendon Injuries of the Hand
The treatment process following Zone 2 flexor tendon injuries, which are particularly controversial for hand surgery, is challenging.
- Trial name
- NCT06356766
- Testing
- Telerehabilitation, Face-to-face rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Istanbul University
Appendicitis Acute, Disbiosis
Differences In Microbiota Profiles Of Pediatric Appendicitis Cases
The microbial profile varies between simple appendicitis (SA) and complicated appendicitis (CA) cases. An appendectomy has been noted to temporarily diminish gut bacterial diversity.
- Conditions
- Appendicitis Acute, Disbiosis, Complicated Appendicitis, Simple Appandiscitis
- Trial name
- NCT07860307
- Testing
- Appendectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Cerebral Hemodynamics, Mechanical Ventilation Strategies
Cerebral Hemodynamic Effects of Individualized PEEP During Robotic Prostatectomy
This randomized clinical trial will compare two approaches to setting positive end-expiratory pressure (PEEP) during robot-assisted radical prostatectomy performed in the Trendelenburg position.
- Conditions
- Cerebral Hemodynamics, Mechanical Ventilation Strategies, Robotic Prostatectomy
- Trial name
- NCT07784010
- Testing
- Individualized PEEP Titration, Standard PEEP Group
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Istanbul University
Intraoperative Hypotension, Spinal Aneshtesia
Dural Sac Area-Guided Spinal Anesthesia Dosing for TURP
This randomized controlled study will evaluate whether individualizing the dose of spinal anesthesia according to the ultrasound-derived dural sac cross-sectional area (DSCSA) can improve hemodynamic stability in patients…
- Conditions
- Intraoperative Hypotension, Spinal Aneshtesia, TURP(Transurethral Resection of Prostate)
- Trial name
- NCT07794852
- Testing
- DSCSA-Guided Individualized Spinal Anesthesia Dosing, Bupivacaine, Fentanyl (FEN)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Hemiplegic Cerebral Palsy, Cerebral Palsy (CP)
Effects of Fun-Core (Child-Friendly Core Stabilization) Exercises on Balance and Functional Mobility in Children With Spastic Cerebral Palsy
A total of 54 children, aged between 6 and 12 years, diagnosed with hemiplegic cerebral palsy and not meeting the exclusion criteria, who registered at the outpatient clinics of the Department of Physical Medicine and…
- Conditions
- Hemiplegic Cerebral Palsy, Cerebral Palsy (CP), Core Stabilization, Exercise
- Trial name
- NCT07233824
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Istanbul University
Perimenopause, Postmenopause
The Effect of Structured Health Information-Seeking Training on Cyberchondria and E-Health Literacy in Menopausal Women: A Randomized Controlled Trial
This randomized controlled study will examine whether two different forms of structured health information-seeking education can help women in perimenopause or postmenopause use online health information more effectively.
- Conditions
- Perimenopause, Postmenopause, Cyberchondria, E-Health Literacy
- Trial name
- NCT07834216
- Testing
- Video-Based Health Information-Seeking Education, Pecha Kucha-Based Health Information-Seeking Education
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Anesthesia, Behavior Change
pEEG-Guided Anesthesia and Behavioral Outcomes in Children
Post-hospitalization behavioral changes are common in children after surgery and general anesthesia and may persist for varying durations depending on individual and perioperative factors.
- Conditions
- Anesthesia, Behavior Change, Behavior Child Problems, Anesthesia Depth Monitoring
- Trial name
- NCT07473024
- Testing
- Processed EEG Monitoring, Standard Anesthesia Management
- Where
- Turkey (Türkiye)
- Volunteers
- 230 people
- Sponsor
- Istanbul University
Gastric Ultrasonography, Supraglottic Airways
Comparison of Gastric Volume Changes After Ventilation With Endotracheal Tube, First-Generation Supraglottic Airway, and Second-Generation Supraglottic Airway in Pediatric Patients
This study aims to compare the gastric volumes of pediatric patients undergoing positive-pressure ventilation with different airway management techniques.
- Conditions
- Gastric Ultrasonography, Supraglottic Airways, Supraglottic Airway Use in Children, Gastric Volume
- Trial name
- NCT07555080
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Istanbul University
Breast Cancer-Related Lymphedema, Lymphedema
Effectiveness of a Tele-Rehabilitation-Based Exercise and Self-Lymphatic Drainage Program Supported by Self-Management for Breast Cancer-Related Lymphedema
A total of 64 women, aged between 20 and 65 years, diagnosed with stage I or II breast cancer-related lymphedema and not meeting the exclusion criteria, who registered at the outpatient clinics of the Department of Physical…
- Trial name
- NCT07794904
- Testing
- Tele-rehabilitation-Based Exercise and Self-Lymphatic Drainage Program, Home-Based Exercise and Self-Lymphatic Drainage Program
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Istanbul University
Knee Osteoarthritis, Hyaluronic Acid
The Effect of Hyaluronic Acid Injection on TNF-Alpha and IL-1β in Knee Osteoarthritis
In this study, the effect of intra-articular HA injection therapy on pre- and post-treatment TNF-alpha and IL-1beta levels and methylation changes in blood and synovial fluid in patients with knee osteoarthritis will be…
- Trial name
- NCT06960564
- Testing
- Hyaluronic Acid injections
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University