Clinical trials: sponsored by Istanbul University
Brain Tumors
Integrated Pulmonary Index and Opioid Based Patient Controlled Analgesia
An optimal analgesic therapy is very important for postoperative recovery. In recent years, several studies showed that the prevalence of the moderate to severe pain after craniotomy ranged from 69 to 87% of patients.
- Trial name
- NCT04313374
- Testing
- Morphine PCA 1 mg, Morphine PCA 0,5 mg
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Varicose Veins of Lower Limb, Varicose Veins and Edema of Leg
Effects of Kinesio Taping Method on Functional Capacity and Quality of Life in Patients With Chronic Venous Disease
The purpose of this randomised and controlled study is to investigate the effects of Kinesio Taping method and compression stockings, combined with exercise therapy, on pain, edema, functional capacity and quality of life in…
- Conditions
- Varicose Veins of Lower Limb, Varicose Veins and Edema of Leg, Chronic Venous Hypertension Peripheral, Spider Veins
- Trial name
- NCT04148950
- Testing
- Kinesio Tape, Compression Stockings, Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Istanbul University
Chronic Postoperative Pain
Data Collection for Prediction of Postoperative Chronic Pain for a Software
Postoperative Persistent Pain (PPP) is reported with a high incidence in adults 11.5-47%. This high incidence effects quality of life of patients causes social-economical problems and arises medico-legal issues.
- Trial name
- NCT02190682
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 733 people
- Sponsor
- Istanbul University
Difficult Intubation
Indirect Laryngoscopy and Ultrasonography in Prediction of Difficult Airway
This study was designed to assess the success of indirect laryngoscopy and ultrasonographic measurements in the prediction of difficult airway.
- Trial name
- NCT04226703
- Testing
- Ultrasonographic upper airway measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Glenohumeral Arthritis
Investigation The Efficacy of Manual Therapy and Exercise in Patients With Glenohumeral Arthritis
The aim of the investigator's study is to compare the efficacy of manual therapy and exercise practices compared to exercise practice in patients with Glenohumeral Arthritis. Thirty volunteer patients will include into the study.
- Trial name
- NCT03958227
- Testing
- Manuel Therapy plus Exercise Intervention, Exercise Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul University
Transversus Abdominis Plane Block
The Efficacy of Different Bupivacaine Concentrations in Pediatric Patients Undergoing Transversus Abdominis Plane Block
This study is designed to compare the analgesic efficacy of different bupivacaine concentrations in pediatric patients undergoing ultrasound-guided transversus abdominis plane (TAP) block for unilateral inguinal hernia repair.
- Trial name
- NCT04202367
- Testing
- 1 mg.kg-1 bupivacaine 0.25%, 1 mg.kg-1 bupivacaine 0.125%
- Volunteers
- 74 people
- Sponsor
- Istanbul University
Obesity, Regional Anesthesia
Regional Anesthesia and Analgesia Techniques in Obese Patients
Obesity is a health problem throughout the world and has increasingly become a widespread epidemic all over the world and also in Turkey.
- Trial name
- NCT04197752
- Testing
- Regional anesthesia/analgesia techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Istanbul University
Muscle Weakness, Metatarsal Fracture
Comparison Different Method Treatment in Tuberosity Fractures of the Proximal Fifth Metatarsal
Fracture of the base of the fifth metatarsal is one of the most common injuries in ankle trauma. There are many conservative treatment protocols for fifth metatarsal base fractures which have up to 99% success.
- Conditions
- Muscle Weakness, Metatarsal Fracture, Healing Fracture of Bone
- Trial name
- NCT04168411
- Testing
- Symptomatic Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Istanbul University
Glomerulonephritis, Membranous
Rituximab in Refractory Primary Membranous Nephropathy
Primary membranous nephropathy (PMN), an autoimmune disease mostly associated with anti-phospholipase-A2-receptor (PLA2R) antibodies, is one of the most common causes of nephrotic syndrome in adults.
- Trial name
- NCT03880643
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Istanbul University
Kidney Transplant; Complications, Hepatitis C, Chronic
Direct Acting Antivirals for HCV Infection in Kidney Transplant Recipients
Chronic hepatitis C virus (HCV) infection, an important cause of morbidity and mortality worldwide, is a significant problem in kidney transplant recipients (KTRs) given its high prevalence in patients undergoing hemodialysis.
- Trial name
- NCT03880682
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul University
Carpal Tunnel Syndrome, Physiotherapy
Efficiency of Mirror Therapy After Carpal Tunnel Surgery
In the randomized controlled study with patients who appropriate the inclusion criteria are divided into two groups by simple drawing method.
- Conditions
- Carpal Tunnel Syndrome, Physiotherapy, Rehabilitation
- Trial name
- NCT03634618
- Testing
- Mirror Therapy, Convantional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Istanbul University
Massage Therapy, Temporomandibular Disorder
Effect of Massage Treatment in Temporomandibular Joint
Temporomandibular disorders (TMD) have multiple and broad clinical effects on orofacial structures and are often diagnosed in patients with a prevalence of between 5% and 12%.
- Trial name
- TMD (NCT04132726)
- Testing
- Massage therapy, non-effective treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Feeding Behavior
Effect of Feeding Positions of Preterm Infants on Some Physiological Characteristics
The purpose of this study is to determine the effect of Semielevated Side-Lying (ESL) and Semielevated Supine Position (ESU) positions used in bottle-feeding of very preterm infants upon their physiological characteristics and…
- Trial name
- NCT02962609
- Testing
- Semielevated Side-lying Position-ESL, Semielevated Supine Position
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Endotracheal Tube Cuff Pressure, Surgery; Ear
Changes of Endotracheal Tube Cuff Pressures After Ear, Head and Neck Surgery Positions
Increased or decreased intracuff pressures (ICPs) of cuffed endotracheal tubes (cETTs) can lead to many morbidities.The ICPs of cETTs can be changed by the the patients' ear and head\&neck surgery positions.
- Conditions
- Endotracheal Tube Cuff Pressure, Surgery; Ear, Surgery; Head and Neck, Position
- Trial name
- NCT04037553
- Testing
- Intracuff pressure measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Istanbul University
Urinary Incontinence
Effect of Glutamine on Urinary Incontinence
The objective of this study is to determine to effect of additional oral glutamine to Kegel exercises on pelvic floor strength and clinical parameters of urinary incontinence in females with either urinary incontinence (stress…
- Trial name
- NCT03265509
- Testing
- glutamine supplementation, fantomalt supplementation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University
Morbid Obesity
Nasal High Flow in Bariatric Surgery
High frequency nasal cannula (HFNC) provides an inspiration O2 fraction of 21-1% and it has a minimal dead space and can be well tolerated due to humidified air.
- Trial name
- NCT04048798
- Testing
- Oxygen therapy via HFNC, Oxygen therapy via face mask
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Diabetes Mellitus, Nerve Block Duration
Infraclavicular Block Properties in Diabetic Patients
Background and objectives: The investigators are performing this study to explore whether the presence of diabetes mellitus (DM) will affect the outcomes of infraclavicular brachial plexus blocks (ICBs) in patients undergoing…
- Conditions
- Diabetes Mellitus, Nerve Block Duration, Pain, Postoperative
- Trial name
- NCT03486535
- Testing
- Infraclavicular Brachial Plexus Blocks
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Thyroid Cancer, Thyroid Nodule
Modified Cormack Lehane Scores Evaluated by Laryngoscopy During Awake Versus Under General Anesthesia
Nowadays, 5-step modified Cormack-Lehane scoring (MCL) system is frequently used in the observation of laryngeal structures by direct laryngoscopy.
- Conditions
- Thyroid Cancer, Thyroid Nodule, Thyroid Adenoma
- Trial name
- NCT03826680
- Testing
- Flexible fiberoptic laryngoscopy, Direct laryngoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Colorectal Cancer
Colorectal Cancer Awareness in Turkey
Colorectal cancer is among the most common types of cancer worldwide. Population-based screening programs for breast, cervical, and colorectal cancer have been introduced as part of cancer control in many high-income countries.
- Trial name
- NCT04020614
- Testing
- Survey
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Istanbul University
Stroke Patients
Effect of mCIMT on Upper Extremity Functions of Stroke Patients With Right/Left Hemiplegia
The investigators aimed To analyze effect of modified constraint induced movement therapy on upper extremity functions and quality of life of subacute and chronic phase stroke patients with right/left hemisphere damage.
- Trial name
- NCT04013750
- Testing
- Modified Constraint Induced Movement Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University