Clinical trials: sponsored by Istanbul University
Phaeochromocytoma Crisis, Hemodynamic Instability
Magnesium and Dexmedetomidine in Pheochromocytoma
Anesthesia management of pheochromocytoma excision surgery is associated with severe hemodynamic fluctuations.The objective of this study was to compare the hypertensive episodes requiring sodium nitroprusside administration…
- Trial name
- NCT05102058
- Testing
- Magnesium-Dexmedetomidine
- Volunteers
- 108 people
- Sponsor
- Istanbul University
Respiratory Distress Syndrome, Adult
Spironolactone in Covid-19 Induced ARDS
This study intended to evaluate the effects of commonly used diuretic, spironolactone, on oxygenation in covid-19 ARDS patients.
- Trial name
- NCT04345887
- Testing
- Spironolactone 100mg
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Respiratory Distress Syndrome, Adult, Ventilation Perfusion Mismatch
Comparison of Extra Vascular Lung Water Index in Covid-19 ARDS and "Typical"ARDS Patients
Covid-19 also primarily affects endothelium that line up the alveoli. The resulting hypoxemia may differ from "typical" Acute Respiratory Distress Syndrome (ARDS) due to maldistribution of perfusion related to the ventilation.
- Conditions
- Respiratory Distress Syndrome, Adult, Ventilation Perfusion Mismatch, Pulmonary Edema, Covid19
- Trial name
- NCT04508933
- Testing
- Extravascular Lung Water Index, Pulmonary Vascular Permeability Index
- Where
- Turkey (Türkiye)
- Sponsor
- Istanbul University - Cerrahpasa
Stroke
The Effect of Home-Based Telerehabilitation in Individuals With Stroke
Stroke is a clinical picture that develops due to occlusion or rupture of cerebral vessels and results in loss of cerebral functions.
- Trial name
- NCT05083195
- Testing
- Home-based Telerehabilitation, Exercise Brochure
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University - Cerrahpasa
Postoperative Pain
Paravertebral Block Versus Erector Spinae Plane Block for Analgesia in Modified Radical Mastectomy
The study is planned to be a single-center randomized, prospective double-blind study and includes patients who planned to be done unilateral MRM (modified radical mastectomy) operation in Istanbul University Istanbul Faculty of…
- Trial name
- NCT05080985
- Testing
- TPVB, ESPB, Bupivacain
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Istanbul University
Diabetes Mellitus, Type 2
The Effect of Single Probiotic on Metabolic Control in Type 2 Diabetes
Recent studies indicate that dysbiosis of intestinal microbiota and low grade inflammation are important pathogenic determinants of type 2 diabetes (T2DM), which has increased in epidemic size over the last 20 years.
- Trial name
- NCT05066152
- Testing
- Lactobacillus rhamnosus GG (ATCC 53103)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Acute Renal Injury
Acute Renal Injury After Major Elective Non-Cardiac Surgery
The study is planned to be a single-center study and includes patients who underwent major surgery within Istanbul University Istanbul Faculty of Medicine with an invasive arterial line.
- Trial name
- NCT04600271
- Testing
- Crystalloid Solutions, Colloid Blood Volume Expanders, blood replacement
- Where
- Turkey (Türkiye)
- Volunteers
- 425 people
- Sponsor
- Istanbul University
Obstructive Sleep Apnea Syndrome
The Effect of Pranayamic Techniques on Obstructive Sleep Apnea Syndrome
Study was planned to investigate the effect of pranayama on dyspnea, daytime sleepiness, cognitive function, quality of life, activities of daily living, functional exercise capacity, physical activity level, sleep quality…
- Trial name
- NCT04632147
- Testing
- Ujjayi pranayama, Nadi-Shodhana pranayama, Sukha pranayama
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Istanbul University - Cerrahpasa
Cerebral Palsy
The Effect of Instrument Assisted Soft Tissue Mobilization and Stretching Exercises in Cerebral Palsy
The aim of the study; To investigate the effects of Instrument Assisted Soft Tissue Mobilizations and Stretching Exercises on flexibility, spasticity, balance and functional mobility in patients with CP.
- Trial name
- IASTM (NCT05042570)
- Testing
- Instrument Assisted Soft Tissue Mobilization, Stretching Exercises, Control Group / NDT program
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Hypotension Drug-Induced, Cerebral Oxygen Saturation
Effect of Controlled Hypotension on Cerebral Oxygen Saturation
For a successful functional endoscopic sinus surgery (FESS), it is crucial to provide effective controlled hypotension to reduce blood loss and provide a relatively blood-free surgical environment to facilitate surgery.
- Trial name
- NCT02967029
- Testing
- Esmolol Hydrochloride, Remifentanil Hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Disability Physical, Neck Pain
Evaluation of the Relationship Between Neck Pain and Ergonomic Factors in Office Workers
Neck pain is a prevalent condition and leading causes of disability particularly in office workers compared to other occupations (1-3).
- Conditions
- Disability Physical, Neck Pain, Ergonomic Factors
- Trial name
- NCT04803760
- Testing
- A self-administered questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 1,028 people
- Sponsor
- Istanbul University
Stroke, Multiple Sclerosis
Development and Application of Tele-Neuro Rehabilitation System
Disability due to neurological diseases is increasing in our country and world. With regular physiotherapy and rehabilitation, as well as patients' symptoms are brought under control, their affected functions in daily life are…
- Conditions
- Stroke, Multiple Sclerosis, Parkinson Disease
- Trial name
- NCT05031403
- Testing
- Telerehabilitaton, Home Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people
- Sponsor
- Istanbul University - Cerrahpasa
Arm, Rheumatic Diseases
Validity and Reliability of "Shriners Hospital Upper Extremity Evaluation" in Children With Rheumatic Disease
The most commonly used performance tests to evaluate upper extremity function in children diagnosed with rheumatic disease are the 9-hole peg test and Jebsen Taylor hand function tests.
- Conditions
- Arm, Rheumatic Diseases, Child, Only
- Trial name
- NCT04685434
- Testing
- Shriners Hospital for Children Upper Extremity Evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Assessment, Self, Stoma Colostomy
The Effect of Self and Peer Assesment Education Given to Nursing Students: Stoma Care Skill Example
Self- and peer-assessment is one of the important methods among student-centered assessment methods. The ability of the student to evaluate himself and his peers provides many contributions to him in his education and…
- Conditions
- Assessment, Self, Stoma Colostomy, Achievement
- Trial name
- NCT05012553
- Testing
- education of self and peer assesment
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Healthy Lifestyle, Preeclampsia
Efficiency of the Web-Based Support Program Based on the Health Promotion Model in Pregnant Women With Preeclampsia
In the literature, it has been reported that health promotion model-based care approaches are beneficial in gaining positive healthy lifestyle behaviors, taking responsibility for the individual's health and increasing the…
- Conditions
- Healthy Lifestyle, Preeclampsia, Pregnancy; Renal Disease
- Trial name
- preeclampsia (NCT05021692)
- Testing
- Web-based support program for pregnant women with preeclampsia based on the Health Promotion Model
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Istanbul University - Cerrahpasa
Subacromial Impingement Syndrome
Effectiveness of Neuromuscular Electrical Stimulation in Patients With Subacromial Impingement Syndrome
Subacromial Impingement Syndrome (SIS) is one of the musculoskeletal system problems. SIS, which is the most common cause of shoulder pain, constitutes 44-65% of complaints of shoulder pain.
- Trial name
- NCT04667273
- Testing
- Neuromuscular Electrical Stimulation (NMES), Exercise Training (ET)
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Istanbul University - Cerrahpasa
Trigger Point Pain, Myofascial
Trigger Point Incidence After Lumbar Disc Herniation Surgery
Our purpose is to determine the incidence of trigger points in patients who remain in a fixed position for a long time during lumbar disc herniation surgery.
- Trial name
- NCT04136197
- Testing
- Manual palpation for incidence determination
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Istanbul University - Cerrahpasa
Hematologic Diseases
Effects of Music Therapy on Sleep Quality in Patients Who Had Hematopoietic Stem Cell Transplantation
In patients undergoing hematopoietic stem cell transplant; Side effects associated with high-dose chemotherapy and radiotherapy, night treatment and care, social isolation cause emotional problems and deterioration in sleep…
- Trial name
- NCT05015140
- Testing
- musıc therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Infant, Newborn, Weight Loss
Effect of Kangaroo Care on Phyiological Weight Loss in Term Newborns
The aim of the study is to evaluate the effect of kangaroo care on physiological weight loss in term newborns.
- Trial name
- NCT05001334
- Testing
- Kangaroo care training
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Istanbul University
COVID-19 Acute Respiratory Distress Syndrome, Hypoxemia
Effects of Low Molecular Weight Heparin Therapy With Soft-Mist Inhaler for COVID-19 Induced Hypoxemia
This is an investigator initiated, single-center, open-label, Phase IIb clinical trial with 40 patients (for a total of 80 patients) to assess efficacy of Low molecular weight heparin using soft mist inhaler in the treatment of…
- Trial name
- NCT04990830
- Testing
- Inhaled Low molecular weight heparin, Standard Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istanbul University
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