Clinical trials: sponsored by KU Leuven
Proprioceptive Training, Low Back Pain
Proprioceptive Training and Low Back Pain
Proprioceptive weighting changes may explain differences in postural control performance. Deficits in proprioception are found in a subgroup of patients with low back pain.
- Trial name
- NCT01505595
- Testing
- Proprioceptive training
- Where
- Belgium
- Volunteers
- 18 people
- Sponsor
- KU Leuven
Osteo Arthritis Knee
Power Production in Older Adults With Knee Osteoarthritis
Knee osteoarthritis is an important cause of functional disabilities at old age. Previous research has demonstrated that individuals with knee osteoarthritis have reduced knee-extensor strength in comparison to healthy…
- Trial name
- NCT03680807
- Testing
- Muscle function test
- Where
- Belgium
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Low Back Pain
Central Proprioceptive Processing and Postural Control in LBP
This project aims to elucidate neural correlates of proprioceptive deficits in patients with recurrent non-specific low back pain, by studying whether brain activation patterns during the processing of proprioceptive signals from…
- Trial name
- NCT03097718
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Chronic Low Back Pain
Efficacy of a Classification Based 'Cognitive Functional Therapy' in Nurses With Non Specific Chronic Low Back Pain
A series of case-studies to explore the efficacy of classification based cognitive functional physiotherapy according to the classification system proposed by Peter O'Sullivan in specific nursing population with non specific…
- Trial name
- NCT01882686
- Testing
- Classification Based Cognitive Functional Therapy
- Where
- Belgium
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Medication and Supplement Use, Pregnant Women
A Cross-sectional Study Evaluating Pregnancy Related Use of Vitamins and Medication
This cross-sectional study will try to give answers to the following project aims: To provide an overview of the prevalence of health products' use among Belgian pregnant women (prescription and OTC medication, vitamin…
- Trial name
- PREVIM (NCT03105583)
- Testing
- Medication use during pregnancy, Supplement use during pregnancy, Vitamin status of a pregnant woman
- Volunteers
- 381 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Cardiovascular Disease
Technology-enabled Cardiac Rehabilitation Through PATHway. Feasibility, Clinical Effectiveness and Cost-effectiveness
The PATHway system is designed to help patients remain physically active and maintain a good cardiovascular health. It proposes a novel approach that aims to empower patients to self-manage their CVD, set within a collaborative…
- Trial name
- PATHway (NCT02717806)
- Testing
- PATHway
- Where
- 3 sites in Belgium, Ireland
- Volunteers
- 120 people
- Sponsor
- KU Leuven
Congenital Heart Defect
Start-to-Sport - Home-based Exercise for Adolescents and Adults With Congenital Heart Disease
Almost 1% of all baby's is born with a heart defect (CHD) and most of them survive. Even though outcomes are good, they need lifelong follow-up because of a higher risk for cardiovascular diseases.
- Trial name
- S2S-ACHD (NCT02240147)
- Testing
- home-based exercise training
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- KU Leuven
Prostate Cancer, Quality of Life
Functional Outcomes and QoL in Patients With High Versus Low and Intermediate Risk Prostate Cancer Treated by RARP
The Be-RALP database is Belgian prospective multicenter database governed by the Belgian cancer registry. This database investigates the status after robot assisted laparoscopic prostatectomy (RALP) in prostate cancer patients.
- Conditions
- Prostate Cancer, Quality of Life, Erectile Function, Urinary Function
- Trial name
- NCT03790995
- Testing
- Robot assisted laparoscopic prostatectomy
- Where
- 25 sites in Belgium
- Volunteers
- 9,235 people
- Sponsor
- KU Leuven
Emotions, Stress
The Role of Short Chain Fatty Acids in Microbiota-gut-brain Axis
The role of short chain fatty acids (SCFA) in the microbiota-gut-brain axis is examined in a sample of healthy volunteers. SCFA are the major products of bacterial fermentation of dietary fiber in the colon, and are hypothesised…
- Conditions
- Emotions, Stress, Fear
- Trial name
- SCFA-AP (NCT03688854)
- Testing
- SCFA mixture
- Where
- Belgium
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Respiratory Disease
Pulmonary Function Test Study - Automated Interpretation
A multicentric study to explore variability when clinicians are intrepreting lung function tests. Comparison with results of in-house built software for automatic interpretation.
- Trial name
- NCT03264417
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Exercise Training
Plyometric Exercise to Improve Rapid Force Production in Older Men
Rapid force production declines as a consequence of ageing. Given the functional relevance of rapid force production, exercise interventions in older adults should aim at improving the capacity to produce force rapidly.
- Trial name
- NCT03645772
- Testing
- Exercise intervention
- Where
- Belgium
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Heart Failure
Protocol of a Pilot Study to Optimize Care for Heart Failure Patients in Primary Care
Heart failure (HF) imposes a burden for patients and health economics. Although guidelines exist, they are not implemented as such in the Belgian health care system.
- Trial name
- NCT02905786
- Testing
- Cobas h232 (Roche Diagnostics), Clinical audit and feedback, Assistance by a specialized HF nurse
- Where
- Belgium
- Volunteers
- 538 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Malignant Mesothelioma
IP3R Modulation by Cancer Genes in Mesothelioma
Obtaining pleural biopsies in cases of malignant mesothelioma to detect molecular mechnisms and signal transduction
- Trial name
- NCT03558932
- Testing
- pleural biopsy
- Volunteers
- 20 people
- Sponsor
- KU Leuven
Diffuse Interstitial Lung Disease
Innovation in Endobronchial Sampling
Evaluating an integrated diagnostic work-up of virtual navigation bronchoscopy (VNB), confocal laser endomicroscopy and micro computerized tomography (micro-CT) in the diagnostic path of pulmonary lesions in the non-oncological…
- Trial name
- NCT02380326
- Testing
- Advanced endoscopic imaging modalities
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- KU Leuven
Interstitial Lung Disease
Diagnostic Value of Transbronchial Lung Cryobiopsy
Evaluating the diagnostic value of transbronchial lung cryobiopsy (TBLC) as well as its procedural feasibility and safety in a prospective series of 20 patients with diffuse interstitial lung diseases (DILD) who are referred for…
- Trial name
- NCT02579304
- Testing
- transbronchial lung cryobiopsy
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- KU Leuven
Critically Ill Patients With a Predicted Prolonged ICU Stay
NMES in Critically Ill Patients
Critically ill patients with a predicted prolonged ICU stay will receive neuromuscular electrical stimulation (NMES) of one quadriceps muscle.
- Trial name
- NESCI (NCT02133300)
- Testing
- electrical stimulation
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- KU Leuven
Pharmacist, Physicians, Primary Care
Exploratory Study to Inventory Opportunities to Optimize Continuity of Pharmacotherapy at Hospital Discharge
Title of the research: Exploratory study to inventory opportunities to optimize continuity of pharmacotherapy at hospital discharge Study area: Care region Leuven (individual interviews), care region Bruges (individual…
- Conditions
- Pharmacist, Physicians, Primary Care, Patient Discharge
- Trial name
- NCT03223584
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- KU Leuven
Breast Cancer
The Distress-barometer: Face-to-face Interviews or Written Self-report Questionnaires?
Breast cancer is the most prevalent cancer among women worldwide [1]. 5 years after diagnosis, up to 87% survives. A substantial group of these survivors report reduced physical, psycho social and cognitive functioning.
- Trial name
- NCT03357744
- Testing
- distress barometer
- Volunteers
- 59 people
- Sponsor
- KU Leuven
Tremor, Limb
Effects of High Amplitude and Focused tACS on Entraining Physiological Tremor
Transcranial alternating current stimulation (tACS) is a noninvasive neuromodulation method that works by passing alternating electric current between electrodes where at least one of them is attached to the head.
- Trial name
- NCT03337334
- Testing
- tACS at tremor frequency
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Medication and Supplement Use During Pregnancy
Retrospective Analysis of Hospital Medical Records on Medication and Supplement Use in Pregnant Women
Monocentric study in University Hospitals Leuven (campus Gasthuisberg). Hospital medical records from all pregnant women who delivered between 01/07/2015 and 31/12/2015 in University Hospitals will be analyzed for the presence of…
- Trial name
- NCT02842216
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- KU Leuven