Clinical trials: sponsored by Kaiser Permanente
Hyperphosphatemia
Transition to Ferric Citrate Among Hemodialysis and Peritoneal Dialysis Patients
Transition to Ferric Citrate among Hemodialysis and Peritoneal Dialysis Patients: A Phase 4 "Real World" Experience Study from Kaiser Permanente Southern California
- Trial name
- NCT03079869
- Testing
- Ferric Citrate
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Kaiser Permanente
Heart Failure, Chronic Kidney Diseases
Kaiser Permanente Evaluation of Medically Tailored Meals in Adults With Medical Conditions at High Readmission Risk
This study is a virtual, remote, decentralized pragmatic clinical trial comparing the efficacy of medically tailored meals alone or medically tailored meals with remote nutritional counseling compared with usual standard of care…
- Conditions
- Heart Failure, Chronic Kidney Diseases, Diabetes Mellitus, Type 2
- Trial name
- KP NOURISH (NCT05166525)
- Testing
- Medically tailored meals
- Where
- 5 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- Kaiser Permanente
Vaccination
Effect of Electronic and Mail Outreach From Primary Care Physicians for COVID-19 Vaccination Among Elderly Patients
This randomized controlled trial tested the effect of culturally tailored and standard electronic secure messages and mailings from patients' primary care physicians to encourage COVID-19 vaccination among adults aged 65 and…
- Trial name
- NCT05096026
- Testing
- Standard PCP Outreach, Culturally Tailored PCP Outreach
- Where
- United States
- Volunteers
- 8,287 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Depression, Suicidal Ideation
UH3 Pragmatic Suicide Prevention Trial
This pragmatic clinical trial will evaluate the effectiveness of two population-based outreach programs for preventing suicide attempts among patients identified as at-risk.
- Trial name
- SPOT (NCT02326883)
- Testing
- Care Management, Skills Training, Usual Care
- Volunteers
- 18,882 people
- Sponsor
- Kaiser Permanente
Physical Activity
An mHealth Mobile Application Supporting Maintenance of Physical Activity Among Men and Women With High Blood Pressure
The aim of this research is to evaluate the efficacy of contextually tailored activity suggestions and activity planning for increasing physical activity among sedentary adults.
- Trial name
- HeartSteps (NCT03937674)
- Testing
- HeartSteps: A just-in-time intervention for increasing physical activity among sedentary adults.
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- Kaiser Permanente
HSV-2 Infection, PreTerm Birth
Comparative Effectiveness of Treatment Options for Genital Herpes Infection to Reduce Adverse Pregnancy Outcomes
Preterm delivery (PTD), together with low birthweight (LBW), is the leading cause of infant death and illness, affecting 500,000 births with annual medical costs of more than $26 billion in the U.S. each year.
- Conditions
- HSV-2 Infection, PreTerm Birth, Pregnancy Complications
- Trial name
- PCORIHSV (NCT02986802)
- Where
- United States
- Volunteers
- 89,132 people
- Sponsor
- Kaiser Permanente
Physical Activity, PreDiabetes
Exercise Promotion in Primary Care
The investigators conducted a pilot study to determine if telephone counseling, in a health care setting that routinely assesses physical activity of its members, is a feasible approach to improve physical activity among patients…
- Conditions
- Physical Activity, PreDiabetes, Diabetes
- Trial name
- EPPC (NCT03429088)
- Testing
- Motivational interviewing telephone counseling
- Volunteers
- 67 people
- Sponsor
- Kaiser Permanente
Cancer of the Breast, Anomaly of Breast
Autologous Fat Grafting of the Breast in Women With Post Lumpectomy Contour Defects
The purpose of the study is to evaluate the safety and efficacy of breast reconstruction using Autologous Fat Grafting (AFG) for women post lumpectomy that have contour defects.
- Trial name
- NCT02302196
- Testing
- Autologous Fat Grafting of the Breast, Control Arm
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Kaiser Permanente
Value-Based Health Insurance
Evaluating the Impact of a Value-based Prescription Drug Formulary
The objective of this study is to evaluate the impact of the value-based formulary on patient out-of-pocket spending and health plan spending as well as the impact of the value-based formulary on medication use, emergency…
- Trial name
- VBF-e (NCT04904055)
- Testing
- Value-based Formulary
- Where
- United States
- Volunteers
- 36,333 people
- Sponsor
- Kaiser Permanente
Anesthesia Morbidity, Osteoarthritis, Knee
Evaluation of Anesthetic Techniques in Outpatient Total Joint Replacement Surgery in an Integrated Health Care Delivery System
The study is a retrospective cohort study of adult patients undergoing outpatient primary unilateral total knee or total hip replacement surgeries from 2017 to 2019 assessing for difference in anesthetic techniques and outcomes.
- Conditions
- Anesthesia Morbidity, Osteoarthritis, Knee, Osteoarthritis, Hip
- Trial name
- NCT04203732
- Testing
- Anesthesia Type
- Where
- United States
- Volunteers
- 12,466 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Chronic Disease, Patient Outcome Assessment
Consumer Health IT Tools: Impact on Experience, Access, and Outcomes for Patients With Complex Chronic Conditions
Patient use of health IT tools to interact with healthcare providers and delivery systems, including exchanging secure messages with their medical providers and using other web-based tools, has great potential to increase patient…
- Conditions
- Chronic Disease, Patient Outcome Assessment, Electronic Health Records
- Trial name
- NCT02292940
- Volunteers
- 168,477 people
- Sponsor
- Kaiser Permanente
Hepatitis C, Chronic
Real World Study: Genotype 1 Chronic Hepatitis C Virus Treatment and Evaluation of Real World SVR and PRO
This is a Phase IV, open-label, multi-center study to evaluate the real world sustained virological response rate, subject adherence, and subject reported outcomes during and after treatment of non-cirrhotic genotype 1 chronic…
- Trial name
- NCT02461745
- Testing
- ombitasvir, paritaprevir/r, dasabuvir + ribavirin, ombitasvir, paritaprevir/r, dasabuvir
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Kaiser Permanente
Advanced Cancer, Depression
POEM (Practice of Embracing Each Moment) Study (Delivery Science)
The objective of the proposed pilot pragmatic cluster randomized trial targeting cancer patients undergoing palliative and supportive therapy and their informal caregivers is to pilot test implementation of mHealth two…
- Conditions
- Advanced Cancer, Depression, Anxiety
- Trial name
- NCT03751995
- Testing
- Mindfulness meditation
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- Kaiser Permanente
Chronic Sinus Infection, Chronic Sinusitis
Impact of Budesonide Irrigations on Patients With Chronic Rhinosinusitis and Impact on Sinus Surgery Rates
This study is intended to assess the impact of a 90 day course of high volume budesonide irrigations for patients who have failed other medical therapy and assessing the impact of the budesonide irrigations on the need for sinus…
- Conditions
- Chronic Sinus Infection, Chronic Sinusitis, Chronic Sinusitis - Ethmoidal, Posterior, Chronic Sinus Congestion
- Trial name
- NCT03519061
- Testing
- Budesonide
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Back Pain, Neck Pain
A Naturalistic Experiment Evaluating the Impact of Medicaid Treatment Reimbursement Changes on Opioid Prescribing and Patient Outcomes Among Patients With Back Pain
Back on Track is a quasi-experimental, mixed-methods study of a unique natural experiment that will answer the question: what is the comparative effectiveness of different payer or health-system strategies that aim to prevent…
- Trial name
- Back on Track (NCT03393143)
- Where
- United States
- Volunteers
- 2,748 people
- Sponsor
- Kaiser Permanente
Blood Pressure
Blood Pressure Checks for Diagnosing Hypertension (BP-CHECK)
Hypertension is usually diagnosed at a clinic or doctor's office when a patient has blood pressure (BP) that is high for several measurements.
- Trial name
- NCT03130257
- Testing
- Clinic Blood Pressure Measurement, Home Blood Pressure Measurement, Kiosk Blood Pressure Measurement
- Where
- United States
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Colorectal Cancer
Systems of Support (SOS) to Increase Colon Cancer Screening and Follow-up
SOS is a four-arm randomized controlled study of ways to increase screening for colorectal cancer. About 40-50% of the people age 50 and older are not up to date on screening.
- Trial name
- SOS (NCT00697047)
- Testing
- Automated Mailing, Automated Mailing Plus Assisted, Auto Plus Assisted Plus Navigation
- Where
- United States
- Volunteers
- 4,653 people
- Sponsor
- Kaiser Permanente
Influenza
Performance Feedback in Health Care
The Southeast Permanente Medical Group (TSPMG) at Kaiser Permanente Georgia provides performance feedback to its providers. The performance feedback designs can vary and change over time in terms of targets, summary statistics…
- Trial name
- NCT04579614
- Testing
- The Impact of Performance Feedback and Variable Goal Setting on Flu Vaccination Success Rates of Providers
- Where
- United States
- Volunteers
- 595 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Diabetes, Weight Loss
De Por Vida: A Diabetes Risk Reduction Intervention for Hispanic Women
This pragmatic randomized clinical trial will assess the efficacy, cost, and sustainability of a culturally tailored weight-loss program targeting obese Hispanic women with pre-diabetes or T2D.
- Conditions
- Diabetes, Weight Loss, PreDiabetes, Obesity
- Trial name
- NCT03113916
- Testing
- Behavioural Lifestyle Intervention
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Acute Coronary Syndrome, Chest Pain
Standardizing Emergency Work-ups Around Risk Data
Chest pain is the second leading reason for emergency department (ED) visits in the United States. Resource utilization for this ED subpopulation is particularly high, in part due to a dearth of accepted standardized clinical…
- Conditions
- Acute Coronary Syndrome, Chest Pain, Risk Reduction
- Trial name
- STEWARD (NCT03286179)
- Testing
- modified HEART score and/or Emergency Department Assessment of Chest pain Risk Score (EDACS)
- Where
- 12 sites in United States
- Volunteers
- 13,419 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente