Clinical trials: sponsored by Kaiser Permanente
Influenza, Vaccination
Kaiser Colorado Flu Nudge
Influenza infection leads to significant morbidity and mortality each year. Influenza vaccines can reduce the risk of flu and the severity of flu illness, In addition, flu vaccinations can reduce flu complications such as…
- Trial name
- NCT07372950
- Testing
- Behavioral economics framed test messaging
- Where
- United States
- Volunteers
- 100,000 people
- Sponsor
- Kaiser Permanente
Chronic Pain
Tailored Non-Pharmacotherapy Services for Chronic Pain
The RESOLVE study is a multicenter comparative effectiveness trial of two cognitive behavioral therapy-based chronic pain (CBT-CP) treatments delivered via telehealth modalities: 1) online program and 2) live, health coach-led…
- Trial name
- RESOLVE (NCT04523714)
- Testing
- Online CBT-CP based program, Virtual health coach-led CBT-CP based program
- Where
- 4 sites in United States
- Volunteers
- 2,333 people
- Sponsor
- Kaiser Permanente
Diabetes Mellitus
ASCEND: ApproacheS to CHC ImplEmeNtation of SDH Data Collection and Action
This work will test a set of strategies for helping community health centers (CHCs) routinely identify and take action on the SDH-related needs of patients with / at risk for DM using a stakeholder-driven process to develop…
- Trial name
- ASCEND (NCT03607617)
- Testing
- SDH Tool
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Cancer
Cancer Financial Experience
This study is a randomized clinical trial designed to test a novel financial navigation intervention. The study assesses the impact of the financial navigation intervention on financial hardship and health-related quality of…
- Trial name
- CAFE (NCT05018000)
- Testing
- Financial navigation, Enhanced usual care
- Where
- United States
- Volunteers
- 371 people
- Sponsor
- Kaiser Permanente
Diabetes Mellitus, Type 2
Kaiser Permanente Evaluating Nutritional Interventions in Food-Insecure High-Risk Adults Study
The goal of this randomized controlled trial is to compare the effect of receiving 6 months of monetary support for healthy food through a food delivery platform on change in glycosylated hemoglobin (HbA1c) levels among adults…
- Trial name
- KP ENRICH (NCT06061861)
- Testing
- Financial support for healthy foods and free home delivery, Free home delivery
- Where
- 2 sites in United States
- Volunteers
- 1,007 people
- Sponsor
- Kaiser Permanente
Chronic Low-back Pain
Acupuncture for Chronic Low Back Pain in Older Adults
The main goal of the BackInAction research study is to determine the effectiveness of a standard course of acupuncture (15 sessions of acupuncture over 3 months) and an enhanced course of acupuncture (an additional 6 sessions of…
- Trial name
- BackInAction (NCT04982315)
- Testing
- Standard Acupuncture, Enhanced Acupuncture
- Where
- 4 sites in United States
- Volunteers
- 807 people
- Sponsor
- Kaiser Permanente
Lung Cancer, Lung Cancer Screening
Multilevel Interventions to Increase Adherence to Lung Cancer Screening
Screening for lung cancer has the potential for a profound public health benefit. Repeat annual screening is necessary for early detection of lung cancer.
- Trial name
- Larch (NCT05747443)
- Testing
- Stepped Reminders, Patient Education
- Where
- United States
- Volunteers
- 1,837 people
- Sponsor
- Kaiser Permanente
Colon Cancer
Study of Colorectal Cancer Screening Options
The investigators propose to evaluate Guardant Health's commercially available colorectal cancer screening assay(Guardant SHIELD) in individuals who are not up to date with CRC screening.
- Trial name
- NCT05987709
- Testing
- GuardantSHIELD Blood Test
- Where
- United States
- Volunteers
- 2,004 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Suicide, Attempted, Suicide, Fatal
Implementation of Suicide Risk Models in Health Systems
The goal of this clinical trial is to evaluate a suicide risk model in patients receiving behavioral health care treatment. The main question it aims to answer is: Does the implementation of the suicide risk model reduce suicide…
- Trial name
- NCT06060535
- Testing
- Suicide Attempt Risk Model Care Pathway
- Where
- 3 sites in United States
- Volunteers
- 394,000 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Breast Cancer, Colorectal Cancer
The Engaging Primary Care in Cancer Survivorship (EPICS) Study
A quasi-experimental non-randomized pre/post with control group trial of two models of cancer survivorship care in early-stage colorectal and breast cancer survivors cared for in a community-based, integrated health care setting.
- Trial name
- EPICS (NCT04745754)
- Testing
- Embedded primary care in cancer survivorship model
- Where
- 13 sites in United States
- Volunteers
- 2,450 people
- Sponsor
- Kaiser Permanente
Type 2 Diabetes Mellitus, Cardiovascular Diseases
Comparison of Type 2 Diabetes Pharmacotherapy Regimens
This study is designed to help patients with type 2 diabetes and their clinicians: (a) identify which glucose lowering medications have the most favorable effects on heart health and other patient-important outcomes, (b) inform…
- Trial name
- ON TARGET DM (NCT05073692)
- Testing
- SU, DPP4, SGLT2i
- Where
- 6 sites in United States
- Volunteers
- 241,981 people
- Sponsor
- Kaiser Permanente
Opioid Tapering
Prescription Opioid Discontinuation: Honoring Patient Insights and Experience to Support Safe and Caring Transitions -- Decision Aid Pilot
Because of recent policies to decrease opioid use, some people using long-term opioid therapy (LTOT) are encouraged or required to stop (discontinue) taking opioids.
- Trial name
- PHOENIX (NCT07202026)
- Testing
- Patient-centered Decision Aid to support long-term opioid therapy tapering
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Kaiser Permanente
Prostate Cancer
Surveillance or Focal Therapy
Patients with newly diagnosed low-intermediate risk prostate cancer often are not advised of all the options in an easy to understand way.
- Trial name
- SOFT (NCT07207902)
- Testing
- Explainer video
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Kaiser Permanente
COVID-19 Testing
COVID-19 Antibody and Reinfection Study
The goal of this study is to establish a cohort of Kaiser Permanente Colorado (KPCO) members who have and have not had COVID-19 infection for serial antibody testing and PCR testing to: 1.
- Trial name
- NCT05365750
- Where
- United States
- Volunteers
- 4,235 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Hereditary Cancer Syndrome
Cancer Health Assessments Reaching Many
The CHARM (Cancer Health Assessment Reaching Many) study will assess the utility of clinical exome sequencing and how it affects care in diverse populations.
- Trial name
- CHARM (NCT03426878)
- Testing
- Modified genetic counseling, Traditional genetic counseling
- Where
- 2 sites in United States
- Volunteers
- 967 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Obesity
Motivational Wellness Coaching to Reduce Childhood Obesity in Families and Kids
Primary care settings lack interventions to address the childhood obesity epidemic that are feasible and sustainable without requiring significant resources.
- Trial name
- WC4K (NCT05143697)
- Testing
- Wellness Coaching for Families and Kids
- Where
- United States
- Volunteers
- 6,600 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Postpartum Depression
Postpartum Wellness
The purpose of this study is to test whether a web-based (eHealth) exercise intervention for new moms at increased risk for postpartum depression increases physical activity and decreases postpartum depression symptoms.
- Trial name
- POW (NCT04414696)
- Testing
- Exercise intervention
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Kaiser Permanente
Solitary Pulmonary Nodule, Coin Lesion, Pulmonary
The Watch the Spot Trial
This study will compare two clinically accepted protocols for surveillance imaging in individuals who are found to have a small pulmonary nodule on chest computed tomography (CT) scans.
- Conditions
- Solitary Pulmonary Nodule, Coin Lesion, Pulmonary, Lung Neoplasms, Carcinoma, Non-small-cell Lung
- Trial name
- WTS (NCT02623712)
- Testing
- More Frequent Surveillance Strategy, Less Frequent Surveillance Strategy
- Where
- United States
- Volunteers
- 34,686 people
- Sponsor
- Kaiser Permanente
Drug Use Disorders, Illicit Drug Use
An Initial Study of the Implementation of Digital Therapeutics for Substance Use Disorders in Primary Care
The DIGITS Trial addresses a critical knowledge gap: How to best implement digital treatments for opioids and other substance use disorders in primary care.
- Conditions
- Drug Use Disorders, Illicit Drug Use, Alcohol-Related Disorders
- Trial name
- DIGITS Pilot (NCT04907045)
- Testing
- Health Coaching, Practice Facilitation, Standard Implementation
- Where
- United States
- Volunteers
- 1,552 people
- Sponsor
- Kaiser Permanente
Post Partum Depression, Perinatal Depression
mHealth Mindfulness Intervention for Pregnant Black and Latina Women at Risk of Postpartum Depression
Postpartum depression (PPD) is associated with significant health consequences for mothers and children, and the current COVID-19 pandemic has had a major impact on the mental health of particularly vulnerable populations…
- Trial name
- NCT05186272
- Testing
- Stress reduction program 'A', Stress reduction program 'B'
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Kaiser Permanente