Clinical trials: sponsored by Kessler Foundation
Stroke
Effect of Transcranial Magnetic Stimulation on Recovery of Upper Limb Among Stroke Survivors
Approximately two thirds of stroke survivors have profoundly impaired function of the upper limb. Currently the main stay of the treatment for upper limb motor function is rehabilitation therapy focusing on repetitive and…
- Trial name
- NCT01938690
- Testing
- Transcranial magnetic stimulation (TMS)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Kessler Foundation
Stroke, Vascular Dementia
Aricept to Improve Functional Tasks in Vascular Dementia
Medications for memory improvement are available but they may not actually improve the ability to do real world tasks. The purpose of this research study is to determine if a medicine used to treat memory problems…
- Conditions
- Stroke, Vascular Dementia, Memory Deficits
- Trial name
- NCT00457769
- Testing
- Donepezil and self-generated memory training, Donepezil and experimenter-administered memory training
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Kessler Foundation
Spatial Neglect, Hemispatial Neglect
A Model to Identify Specific Predictors of Spatial Neglect Recovery
This study examines methods to better predict improvement of a hidden disability of functional vision, spatial neglect, following stroke.
- Conditions
- Spatial Neglect, Hemispatial Neglect, Hemineglect, Unilateral Neglect
- Trial name
- NCT00990353
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Kessler Foundation
Refractory Epilepsy
Feasibility of HOBSCOTCH Telehealth Intervention in Refractory Epilepsy
The purpose of this study is to see whether a phone-intervention called HOBSCOTCH will improve health, daily functioning and quality of life among patients with refractory epilepsy.
- Trial name
- HOBSCOTCH (NCT04240977)
- Testing
- HOBSCOTCH: "Home-Based Self-Management and Cognitive Training Changes Lives"
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Kessler Foundation
Breast Cancer
Neurophysiological Evaluation of Training Effect on Cancer-Related Weakness
Breast cancer patients often suffer from long-term physical symptoms of weakness. In this study, investigators propose to compare how two different low intensity physical exercise training programs can improve handgrip strength…
- Trial name
- NCT02844504
- Testing
- Low Intensity Exercise Training 1, Low Intensity Exercise Training 2
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Spinal Cord Injuries
Longitudinal Assessment of Spinal Cord Structural Plasticity Using DTI in SCI Patients
This study will apply novel magnetic resonance imaging (MRI) techniques to investigation of spinal cord injury (SCI) to learn how nerve fibers repair and neural cells regain ability to control muscle during the rehabilitation.
- Trial name
- NCT03069222
- Testing
- Standard Rehabilitative Treatment
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Multiple Sclerosis
Remediation of Emotional Processing Deficits in MS
This study will test the effectiveness of an emotional processing intervention in individuals with MS in a double blind placebo controlled randomized clinical trial.
- Trial name
- NCT03373344
- Testing
- Emotional Processing Training
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Kessler Foundation
Multiple Sclerosis, Traumatic Brain Injury
Remediation of Emotional Deficits in Multiple Sclerosis and Traumatic Brain Injury
This study will examine the efficacy of a clinical intervention for improving emotional processing in individuals with MS and TBI.(1)The main outcome measure will be changes in emotional processing measures from pre to post…
- Trial name
- NCT04408274
- Testing
- Emotional Processing Training
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Kessler Foundation
Chronic Pain, Spinal Cord Injuries
Improving Functioning in Persons With Chronic Pain Post-SCI Through Virtual Classroom Education
Chronic pain (pain that is that is present for a long period of time) is very common among people with spinal cord injury (SCI).
- Trial name
- NCT02561676
- Testing
- Education Program Type 1, Education Program Type 2
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Kessler Foundation
Spinal Cord Injury, Chronic Pain
Education Interventions for Self-Management of Pain Post-SCI: A Pilot Study
Chronic pain (pain that is that is present for a long period of time) is very common among people with spinal cord injury (SCI). Unfortunately, chronic pain is very difficult to treat.
- Trial name
- NCT02262234
- Testing
- Education Program Type 1, Education Program Type 2
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Kessler Foundation
Cognitive Impairment in Multiple Sclerosis
Intellectual Enrichment to Build Cognitive Reserve in MS
Cognitive problems are a primary concern for people with multiple sclerosis. In many cases, people with MS report these issues to be more debilitating than the motor symptoms that are targeted by most treatment strategies.
- Trial name
- NCT01978574
- Testing
- Intellectual Enrichment daily activities, Intellectual Enrichment documentary videos
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Kessler Foundation
Multiple Sclerosis
Speed of Processing Training to Improve Cognition in Multiple Sclerosis
The purpose of this research study is to investigate the effectiveness of a computerized technique designed to improve processing speed (i.e.
- Trial name
- NCT02301260
- Testing
- Speed of Processing Training (SPT)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Kessler Foundation
Shoulder Pain, Shoulder Impingement Syndrome
Micro-Fragmented Adipose Tissue (Lipogems®) Injection for Chronic Shoulder Pain in Persons With Spinal Cord Injury
Rotator cuff disease (i.e., rotator cuff tendinopathy or tear) is a common cause of shoulder pain in persons with chronic spinal cord injury (SCI).
- Conditions
- Shoulder Pain, Shoulder Impingement Syndrome, Rotator Cuff Impingement Syndrome, Rotator Cuff Tendinitis
- Trial name
- NCT03167138
- Testing
- Autologous micro-fragmented adipose tissue, Lipogems system
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Kessler Foundation
Spinal Cord Injuries, Urinary Bladder, Neurogenic
Mirabegron and Oxybutynin Safety and Efficacy Trial in Spinal Cord Injury
The purpose of this research study is to determine the effectiveness and safety of mirabegron compared to oxybutynin chloride immediate release (oxybutynin IR) for a condition called neurogenic detrusor overactivity in…
- Trial name
- MOSET-SCI (NCT03187795)
- Testing
- Oxybutynin Chloride IR, Mirabegron
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Kessler Foundation
Brain Injuries, Traumatic
Evaluating the Effectiveness of Treatment for Metacognition in Moderate and Severe Traumatic Brain Injury
Metacognition, in-the-moment awareness of performance while engaging in cognitive tasks, is negatively affected by traumatic brain injury (TBI).
- Trial name
- NCT03169647
- Testing
- Listening-based intervention
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Kessler Foundation
Multiple Sclerosis
The SEMS Project: Staying Employed With MS
Description of Project: Multiple sclerosis (MS), a disorder of young and middle aged adults, is known to have a grave impact on one's well-being and incurs a significant cost to society due to the nearly 80% rate of unemployment.
- Trial name
- NCT03647904
- Testing
- SEMS Project
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Kessler Foundation
Traumatic Brain Injury, Brain Injuries, Traumatic
Training Executive Functions to Facilitate Recovery Following Traumatic Brain Injury
The purpose of this research study is to investigate different types of task training to determine if training improves thinking processes following traumatic brain injury.
- Trial name
- NCT01993407
- Testing
- Task Switching Training, Control Task
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Breast Cancer
Chemotherapy Effect on Brain Structure, Neurophysiology and Psychomotor Behavior in Breast Cancer Patients
Some cancer patients report experiencing mild problems with thinking during or following chemotherapy. Symptoms include problems concentrating, slow thinking, some gaps in memory and difficulty performing complex or multi-tasks.
- Trial name
- NCT02896504
- Testing
- Exposure: Adjuvant chemotherapy treatment, Exposure: Adjuvant hormonal therapy treatment
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Spinal Cord Injury
Combination Therapy With Dalfampridine and Locomotor Training for Chronic, Motor Incomplete Spinal Cord Injury
The purpose of this study is to determine the efficacy, safety, and tolerability of treatment with dalfampridine in combination with locomotor training in persons with chronic, motor incomplete SCI.
- Trial name
- NCT01621113
- Testing
- Dalfampridine
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Kessler Foundation
Psychosocial Problems
Advances in Treatment: Examining the Effectiveness of a Behavioral Intervention.
The purpose of this research is to investigate the influence a mindfulness based cognitive therapy (MBCT) intervention will have on internalizing and externalizing problems in children and adolescents that have suffered a…
- Trial name
- NCT03282500
- Testing
- Mindfulness Based Cognitive Therapy
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Kessler Foundation