Clinical trials: sponsored by Laval University
Transition, Emergencies
The LEARNING WISDOM Phase II Scale up Project
Inspired by the Acute Care for Elders program at Mount Sinai Hospital, this study aims to improve care for elderly patients in four hospitals of Chaudière-Appalaches.
- Conditions
- Transition, Emergencies, Health Care Utilization, Frailty
- Trial name
- NCT04093245
- Testing
- GEM nurse, pre- and post-hospitalization medication list reconciliation, systematic discharge summaries
- Where
- Canada
- Volunteers
- 4,000 people
- Sponsor
- Laval University
Anterior Cruciate Ligament Injuries, ACL
Laval University Rouge et or Post ACL Surgery Program Effectiveness
The main objective is to compare the effectiveness of two readaptation programs post anterior cruciate ligament surgery. Laval University Rouge et or program is to be compared with the intervention guide from the CHU.
- Trial name
- NCT04137003
- Testing
- Rouge et Or Program, CHU intervention guide
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Laval University
Mild Traumatic Brain Injury, Emergencies
Wiki Head CT Choice Study: Adaptation of US Two Decision Aids to a Québec Local Context
This study aims to adapt two decision aids (DAs) (pediatric and adult) developed in the United States to the Quebec context to develop context-adapted tools and training program that will facilitate the process of shared…
- Conditions
- Mild Traumatic Brain Injury, Emergencies, Decision-making
- Trial name
- NCT04140084
- Testing
- Real-life clinical meetings
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Laval University
ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
Predictive Factors for a Successful Return to Run After ACL-R
After anterior cruciate ligament (LCA) rupture, the recommended treatment for athletes is the surgical reconstruction of the ligament (ACL-R), followed by a long rehabilitation period.
- Trial name
- NCT04130308
- Testing
- Retrun to run protocol
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Laval University
Obstructive Sleep Apnea, Treatment Compliance
Impact of Automatic Positive Airway Pressure on Treatment Compliance in OSA Patients Awaiting Bariatric Surgery
Obstructive sleep apnea (OSA) is a syndrome characterized by intermittent dynamic obstruction of the upper airways that causes a fall in oxygen saturation, reflex sympathetic activation and sleep micro-arousals.
- Conditions
- Obstructive Sleep Apnea, Treatment Compliance, Automatic Positive Airway Pressure
- Trial name
- APAP-CPAP (NCT02209220)
- Testing
- Positive airway pressure for the treatment of OSA
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Laval University
Decision Making, Resuscitation
Evaluation of a Decision Aid About Life-sustaining Therapies
Introduction: Clinical practice guidelines recommend shared decision making (SDM) to facilitate goals-of-care discussions. This study will train clinicians about how to use a context-adapted decision aid (DA) and SDM to conduct…
- Conditions
- Decision Making, Resuscitation, Intensive Care Unit, Goals-of-care
- Trial name
- NCT04034979
- Testing
- decision aid
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- Laval University
Trauma
The WikiTrauma Interrupted Time Series Protocol
The purpose of this study is to study the combined effect of WikiTrauma, a free collaborative database of clinical decision support tools, and Wiki101, a training course teaching participants how to use WikiTrauma, on the quality…
- Trial name
- WikiTrauma (NCT04035772)
- Testing
- Wiki101 and WikiTrauma
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Laval University
Chronic Obstructive Pulmonary Disease, Nocturnal Desaturation
The International Nocturnal Oxygen (INOX) Trial
This multicenter randomized placebo controlled trial aims to determine if in patients with COPD not qualifying for LTOT but presenting significant nocturnal arterial oxygen desaturation, whether nocturnal oxygen therapy provided…
- Trial name
- INOX (NCT01044628)
- Testing
- Concentrator
- Where
- 28 sites in Canada, France and 2 more
- Volunteers
- 243 people
- Sponsor
- Laval University
COPD
Ultibro® Versus Spiriva® Alone to Reduce Exertional Dyspnea in Patients With Moderate to Severe COPD
The investigators will compare the reduction in Borg dyspnea score during the 3-min constant rate shuttle walking test after 3 weeks of indacaterol 110 µg/Glycopyrronium 50 µg (Ultibro®) versus Tiotropium 18 µg (Spiriva®) alone…
- Trial name
- RED (NCT02567214)
- Testing
- Ultibro®, Spiriva®
- Where
- 3 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Laval University
Rotator Cuff Tendinopathy
Effects of Kinesiotaping on Symptoms, Functional Limitations, and Underlying Deficits of Patients With Rotator Cuff Tendinopathy
Introduction: Rotator cuff tendinopathy (RCTe) is the most frequent cause of shoulder pain, resulting in considerable losses to society and public resources.
- Trial name
- NCT02881021
- Testing
- Rehabilitation program, Kinesiotaping
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- Laval University
Streptococcus Group B
Development and Optimization of a GBS Diagnostic Test
The purpose of this clinical study is to develop an easily performed test to detect Group B Streptococcus (GBS) in pregnant women at the time of delivery, which would allow health care providers to make an accurate and rapid…
- Trial name
- NCT00322829
- Where
- Canada
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Laval University
Lung Diseases, Obstructive
Impacts of a Continuing Education Activity Targeted at COPD Case Managers
This study aims to compare the impacts of two versions of a continuing education activity targeted at COPD case managers on educational outcomes: 1) participation; 2) satisfaction; 3) learning; 4) competence; 5) performance; 6)…
- Trial name
- NCT02870998
- Testing
- Active learning, Passive learning
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Laval University
Acute Rotator Cuff Tendinopathy
Comparison of Two Treatments for Acute Rotator Cuff Tendinopathy
The primary objective of this study is to compare the short-term effectiveness (2 and 6 weeks following the start of the rehabilitation program), in terms of symptoms and functional limitations, of a rehabilitation program…
- Trial name
- NCT02813304
- Testing
- Gradual reloading, Rest and cryotherapy
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- Laval University
Migraine
Clopidogrel For the Prevention of New Onset Migraine Headache Following Transcatheter Closure of Atrial Septal Defects
The addition of clopidogrel on top of aspirin may reduce the occurrence of new-onset migraine headache episodes following transcatheter ASD closure.
- Trial name
- CANOA (NCT00799045)
- Testing
- Clopidogrel
- Where
- Canada
- Volunteers
- 220 people
- Sponsor
- Laval University
Asthma, Allergic Rhinitis
Nasal Allergen Challenge in Rhinitic Subjects
Background: Nasal allergen challenge (NAC) is useful to study the pathophysiology of rhinitis, and multiple challenges may more adequately approximate natural exposure.
- Trial name
- NCT01286129
- Testing
- Nasal allergen challenge
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Laval University
Asthma, COPD
The Mixed Phenotype of Asthma and COPD: the Overlap Syndrome
RATIONALE: In asthmatic subjects, smoking can lead to several changes in disease characterictics. in smokers of more than 20 pack-years, chronic obstructive pulmonary disease (COPD) can be associated with asthma, also called…
- Trial name
- NCT03817333
- Where
- Canada
- Volunteers
- 115 people
- Sponsor
- Laval University
HPV Vaccines Immunogenicity and Safety
Immunogenicity and Safety of Gardasil-9 and Cervarix
A ninevalent HPV vaccine (Gardasil-9) has been recently approved for clinical use. No data on immunogenicity and safety of interchangeable use of the ninevalent and the bivalent vaccine (Cervarix) are available.
- Trial name
- NCT02567955
- Testing
- Immunogenicity two doses of Gardasil-9, Immunogenicity Cervarix and Gardasil-9
- Where
- Canada
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- Laval University
Diet Habit
Family and Web-based Nutrition Intervention to Increase Vegetable, Fruit, and Dairy Intakes in Children
Considering the high prevalence of childhood obesity worldwide, effective interventions are needed . Parental involvement in interventions and the use of web-based modalities appear to be promising approaches.
- Trial name
- NCT03798808
- Testing
- Consumption of fruits, vegetables and dairy products
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Laval University
Asthma, Eosinophilic Asthma
Intense Airway Eosinophilia in Asthma
In asthma, the type and importance of the inflammatory response in the airways has allows identification of different phenotypes.
- Trial name
- NCT03696914
- Where
- Canada
- Volunteers
- 918 people
- Sponsor
- Laval University
Healthy
Enhancing Knowledge Translation in Nutrition Through a Healthy Eating Blog
The purpose of this study is to evaluate the effects of an evidence-based healthy eating blog on dietary behaviors of mothers
- Trial name
- NCT03156803
- Testing
- Healthy eating blog
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Laval University