Clinical trials: sponsored by Laval University
Cardiac Surgery, Mechanically Ventilated Patients
Pilot Evaluation of Closed Loop Ventilation and Oxygen Controller
The study compares automated settings (Intellivent) with protocolized settings of the ventilator after cardiac surgery. The settings concern the respiratory rate, the inspiratory and expiratory pressure and FiO2.
- Trial name
- CLOSER1 (NCT01090258)
- Testing
- Hamilton ventilator (G5 modify to S1) Automated settings, Hamilton ventilator (G5) protocolized settings
- Volunteers
- 60 people
- Sponsor
- Laval University
Insulin Sensitivity, Polycystic Ovarian Syndrome
Assessment of Cod Protein as an Insulin-sensitizing Agent in Women With Polycystic Ovary Syndrome.
The objective of our study is to determine the effects of fish protein on insulin sensitivity in PCOS women with insulin resistance, and its mechanism of action on glucose and endocrine metabolism.
- Trial name
- PCOS (NCT01766557)
- Testing
- Semi-controlled nutritional intervention with fish protein diet, Semi-controlled intervention with other animal proteins
- Where
- Canada
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Laval University
Hypertension, Cardiovascular Diseases
Impact of Dairy Consumption on Hypertension: a Clinical Study
Hypertension and endothelial dysfunction are being increasingly recognized as key etiological factors in the development of atherosclerosis and subsequent cardiovascular disease (CVD).
- Trial name
- PLAT (NCT01776216)
- Testing
- Dairy diet, Control diet
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Laval University
Pulmonary Disease, Chronic Obstructive
Muscle Metabolism and Oxygenation During Localized Fatigue-exercise in COPD
The purpose of this study is to investigate whether a localized exercise, in which cardiorespiratory demand is reduced, will result in greater limb muscle fatigue in patients with COPD as a consequence of muscle oxygenation and…
- Trial name
- NCT01909544
- Testing
- Fatiguing exercise
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Laval University
Brain Injury
Evaluation of the Acceptability, Feasibility and Effectiveness of Two Methods of Involvement of Patients With Cognitive Disability in Clinical Guidelines Development: a Randomized Crossover Pilot Trial
There is a lack of evidence about the best method to involve the patient and population (IPP) into clinical practice guidelines (CPG) development.
- Trial name
- NCT02023138
- Testing
- Focus group, Wiki
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Laval University
Stable Angina, Unstable Angina
Low Rate Fluoroscopy to Reduce Radiation Dose During Coronary Angiography and Intervention
Objectives: To determine the efficacy of low rate fluoroscopy at 7.5 frames per second (FPS) vs. conventional 15 FPS for reduction of operator and patient radiation dose during diagnostic coronary angiography and percutaneous…
- Conditions
- Stable Angina, Unstable Angina, Acute Coronary Syndrome
- Trial name
- NCT01990924
- Testing
- 15 FPS, 7.5 FPS
- Where
- Canada
- Volunteers
- 385 people
- Sponsor
- Laval University
Moderate Chronic Obstructive Pulmonary Disease, Severe Chronic Obstructive Pulmonary Disease
Sensitivity of the Step Test to Detect Improvement in Dyspnea Following Bronchodilation in Patients With Chronic Obstructive Pulmonary Disease
During the previous phases of the project (Phase I and II), two new field tests have been designed and validated for an integration in a primary care setting in Chronic Obstructive Pulmonary Disease (COPD).
- Conditions
- Moderate Chronic Obstructive Pulmonary Disease, Severe Chronic Obstructive Pulmonary Disease, Dyspnea
- Trial name
- CODEx (NCT01655199)
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- Laval University
Obesity
Dissemination of the "Choisir de Maigrir?" Program
The Québec government launched in October 2006 an action plan (PAG) to reduce the prevalence of overweight and obesity among young people and adults by 2012.
- Trial name
- CHOIX-CSSS (NCT01640821)
- Testing
- CdM? program
- Where
- Canada
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Laval University
Satisfaction
Comparison of Patient Comfort With the Nasal and Oral Insertion of the Endobronchial Ultrasound Bronchoscope
The aim of this study is to determine if the insertion of the linear endobronchial ultrasound bronchoscope is more comfortable for patients when done through the nose compared to its insertion through the mouth.
- Trial name
- NCT01742195
- Testing
- Oral EBUS insertion, Nasal EBUS insertion
- Where
- Canada
- Volunteers
- 220 people
- Sponsor
- Laval University
Cardiovascular Diseases
Effects of the Mediterranean Diet on Cardiovascular Risk Profile in Men and Women (ALIMED)-Part 2
The purpose of this study is to document differences between men and women (referred here as gender differences) in diet adherence and in changes in specific dietary intakes and energy density in response to a 12-week nutritional…
- Trial name
- NCT01852721
- Testing
- Experimental: Men and Mediterranean diet, Experimental: Women and Mediterranean diet
- Where
- Canada
- Volunteers
- 123 people
- Sponsor
- Laval University
Chronic Obstructive Pulmonary Disease
Modulation of Dyspnea Perception During Exercise in COPD Patients Using Attentional Distraction
Chronic obstructive pulmonary disease (COPD) is a major health problem whose prevalence is increasing rapidly. The gradual decrease in exercise tolerance is one of the usual consequences of COPD that affects the functional…
- Trial name
- DVD (NCT01902927)
- Testing
- Attentional distraction using IAPS protocol (standardized images)
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Laval University
Radiculopathy
Effect of Mobilizations and Exercises Targeting the Opening of Intervertebral Foramens Following Cervical Radiculopathy
The primary objective of this randomised clinical trial (RCT) is to compare, in terms of disability and pain, an intervention targeting the opening of intervertebral foramens to a conventional physiotherapy intervention, in…
- Trial name
- NCT01500044
- Testing
- Program targeting the opening of foramen, Conventional Rehabilitation Program
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Laval University
Chronic Insomnia
Cognitive-Behavior Therapy for Insomnia
Insomnia is a prevalent public health problem affecting large segments of the population on an occasional, recurrent, or chronic basis.
- Trial name
- NCT00869934
- Testing
- Cognitive-Behavior Therapy, Behavior Therapy, Cognitive Therapy
- Where
- 2 sites in United States, Canada
- Volunteers
- 186 people
- Sponsor
- Laval University
Uterine Atony, Post-partum Hemorrhage
Comparison of Two Doses of Carbetocin for Prevention of Uterine Atony, During Elective Cesarean Section
The purpose of this study is to evaluate the effectiveness of two doses of carbetocin (50 mcg vs 100 mcg) in preventing uterine atony during elective cesarean section.
- Trial name
- NCT01630187
- Testing
- Carbetocin
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- Laval University
Hepatitis B, Vaccination
Long Term Immunogenicity Study of Engerix-B Vaccine in 10 Year Old Children and the Effect of Booster Injections
Hepatitis B immunization has been offered to all grade 4 students (age 9-10) in the province of Quebec, using Engerix-B at a dose of 10 mkg.
- Trial name
- NCT00169858
- Testing
- Engerix-B
- Where
- Canada
- Volunteers
- 1,129 people, healthy volunteers welcome
- Sponsor
- Laval University
Solar Skin Damage
Flavanols and Skin Photo Protection: a Clinical Trial
As flavanols have antioxidants, anti-inflammatory and anti-DNA damaging effects and may increase microcirculation in skin, the purpose of the study is to investigate the chronic effect of flavanol-rich chocolate as an effective…
- Trial name
- CHOCOPO (NCT01444625)
- Testing
- Flavanol-rich chocolate, Flavanol-free chocolate
- Where
- Canada
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Laval University
Asthma, Rhinitis
Validation of the Rhinitis Control Scoring System (RCSS)
Many patients suffering from allergic rhinitis do not recognize or perceive their symptoms. Instruments have been developed to assess quality of life in rhinitis, asthma or both, but there is a need to develop validated tools or…
- Trial name
- RCSS (NCT00967967)
- Testing
- Medication Mometasone furoate and desloratadine
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Laval University
Asthma
Evaluation of Decisional Conflict and Needs Assessment in Asthma Management
Many patients suffering from asthma are not compliant to their treatment and consequently, are not well controlled. Shared decision making intervention has shown an improvement in the outcome of patients with chronic disease.
- Trial name
- NCT01520883
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Laval University
Sleep Initiation and Maintenance Disorders
Behavioral and Pharmacological Treatment for Insomnia
This study will evaluate the long- and short-term effects of cognitive-behavior therapy (CBT), alone and in combination with zolpidem (Ambien®), for chronic insomnia.
- Trial name
- NCT00042146
- Testing
- Cognitive-behavior therapy, zolpidem
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Laval University
Asthma
Role of Airway Hyperresponsiveness on Performance in Elite Swimmers.
The prevalence of airway hyperresponsiveness (AHR) is very high in elite swimmers, reaching 80% in certain studies. Repeated Chlorine-derivatives exposure may be a major causative factor for its development.
- Trial name
- NCT00876135
- Testing
- Ventolin
- Where
- Canada
- Volunteers
- 57 people
- Sponsor
- Laval University