Clinical trials: sponsored by Laval University
Obesity
Effects of a Probiotic on Body Weight
Probiotics administration is associated with health benefits on gut barrier integrity and immunological functions of the gastrointestinal tract.
- Trial name
- NCT01106924
- Testing
- Probiotic
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Laval University
Double Lumen Tube Intubation
The New GlideRite DLT Stylet®: An Observational Study
Thoracic surgeries usually require lung isolation techniques. Double-lumen tube (DLT), either right or left sided, is the most frequent tool used to realize this technique.
- Trial name
- NCT01308918
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Laval University
Bariatric Surgery, Obesity
Impact of Weight Loss Following Bariatric Surgery on Pulmonary Function in Patients With Morbid Obesity
Increase in body mass index (BMI)is associated with a decrease in expiratory flows.Obesity is also associated with an increased prevalence of asthma.Consequences of obesity on respiratory function and on bronchial responsiveness…
- Conditions
- Bariatric Surgery, Obesity, Respiratory Diseases
- Trial name
- NCT00532896
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Laval University
Asthma
Persistence of Airway Inflammation and Remodeling in Subjects With Symptomatic or Complete Asthma Remission
This study aims at determining the patterns of asthma remission, the prevalence of these different patterns, the various factors associated with such remissions and possible recurrences of asthma, in order to determine the…
- Trial name
- NCT00526019
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Laval University
Asthma, Obesity
Characterisation of Asthma in Obese Subjects
Our hypothesis: Obese subjects with a physician's made diagnosis of asthma have a poorer asthma control than asthmatics with normal weight, less variability of peak expiratory flows (PEF) and bronchodilator response,increased…
- Trial name
- NCT00532831
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- Laval University
Obesity, Asthma
Obesity and Asthma:a Specific Phenotype
Clinicians frequently observed that obese women referred for severe asthma do not respond to treatment. These patients, despite the presence of wheezing, often have normal expiratory flows and normal or "borderline" airway…
- Trial name
- ORPA (NCT00532363)
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- Laval University
Coronary Artery Disease
(EASY)-IMProving Adherence to Clopidogrel Trial (IMPACT))
The purpose of this study is to test the impact of a multidisciplinary approach to improve the adhesion and persistence to Clopidogrel therapy.
- Trial name
- EASY-IMPACT (NCT01134679)
- Testing
- Multi-disciplinary disease management approach
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- Laval University
Eating, Obesity
(Mis)Perceptions About Healthy Eating: Effects on Food Intake and Appetite in Men and Women
In the face of an increased prevalence of obesity and chronic diseases in Canada, much effort has been invested to educate the population about healthy eating.
- Trial name
- COLLATION (NCT01141140)
- Testing
- Healthy, Diet, Unhealthy
- Where
- Canada
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- Laval University
Chronic Obstructive Pulmonary Disease
Impact of Muscle Afferent Feedback During Exercise in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Recently, direct evidences point to the contributing role of peripheral muscle fatigue in exercise tolerance among patients with COPD.
- Trial name
- NCT01522729
- Testing
- Fentanyl
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Laval University
Myocardial Infarction, Ischemia
A Randomized Trial of Early Discharge After Trans-radial Stenting of Coronary Arteries in Acute MI
HYPOTHESES 1. Bolus administration of total abciximab dose provides superior maximal and mean platelet aggregation inhibition (PAI) compared with standard bolus (0.25 mg/kg) administration. 2.
- Trial name
- EASY-MI (NCT00440778)
- Testing
- Abciximab
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- Laval University
Coronary Artery Bypass Grafting
Treatment of Moderate Vein Graft Lesions With Paclitaxel Drug Eluting Stents: The VELETI Trial
HYPOTHESIS 1. Sealing moderate SVG lesions with the TAXUS stent prevents SVG atherosclerosis progression as evaluated by IVUS. 2.
- Trial name
- VELETI (NCT00289835)
- Testing
- Paclitaxel eluting stent
- Where
- Canada
- Volunteers
- 57 people
- Sponsor
- Laval University
Overweight
Effects of a Health-At-Every-Size Approach on Weight Management in Premenopausal Overweight Women
The purpose of this study is to measure the effects of a Health-At-Every-Size (HAES) approach on global health status of premenopausal overweight women preoccupied about their weight and who have been unsuccessful in previous…
- Trial name
- CHOIX (NCT01240499)
- Testing
- Health-At-Every-Size (HAES)
- Where
- Canada
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Laval University
Cardiovascular Diseases
Effects of the Mediterranean Diet on Cardiovascular Risk Profile in Men and Women
The purpose of this study is to document differences between men and women in changes in metabolic variables associated with cardiovascular risk in response to a 4 weeks isocaloric controlled nutritional intervention based on the…
- Trial name
- ALIMED (NCT01293344)
- Testing
- Controlled nutritional intervention based on the Mediterranean diet
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Laval University
Dystrophia Myotonica 1
Methylphenidate in Myotonic Dystrophy Type 1
The purpose of this study is to determine whether methylphenidate is effective in the treatment of excessive daytime sleepiness due to myotonic dystrophy type 1 (DM1).
- Trial name
- NCT01421992
- Testing
- Methylphenidate
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- Laval University
Chronic Obstructive Pulmonary Disease
Effects of Cardioselective β-blockers on Dynamic Hyperinflation in COPD
Patients with chronic obstructive pulmonary disease (COPD) are at greater risk of suffering from diseases for which beta-blockers may be indicated and effective.
- Trial name
- NCT01273298
- Testing
- Bisoprolol
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- Laval University
Chronic Obstructive Pulmonary Disease (COPD)
Effects of Advair® in Outpatients With Chronic Obstructive Pulmonary Disease (COPD) Acute Exacerbation
Short course of steroids in COPD exacerbation improves FEV1 and decreases the relapse rate. However, some concerns remain about using systemic steroids for all patients with acute exacerbation.
- Trial name
- NCT00531791
- Testing
- prednisone group, Advair group
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- Laval University
Mild Chronic Obstructive Pulmonary Disease, Respiratory Symptoms
GOLD Stage I Chronic Obstructive Pulmonary Disease (COPD)
Recently integrated in clinical practice, the Global Initiative for Chronic Obstructive Lung Disease (GOLD) classification states that a mild (stage I) chronic obstructive pulmonary disease (COPD) is present, in a smoker, when…
- Conditions
- Mild Chronic Obstructive Pulmonary Disease, Respiratory Symptoms, Physical Activity
- Trial name
- GOLD (NCT01360788)
- Where
- Canada
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Laval University
Chronic Obstructive Pulmonary Disease
Effects of Tiotropium on Walking Capacity in Patients With COPD
This study was designed to test the following hypothesis: A) The acute and long-term (3 weeks) bronchodilator-induced changes in exercise tolerance and in the physiological response during the endurance shuttle walk will be…
- Trial name
- NCT01307189
- Testing
- Tiotropium
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- Laval University
Asthma, Cardiovascular Diseases
Respiratory Health of Elite Athletes
Eleven National Sports Teams are located in the Quebec Metropolitan Area. In these groups, many athletes are aiming for Olympic medals in Beijing 2008 and Vancouver 2010 Olympic Games.
- Conditions
- Asthma, Cardiovascular Diseases, Metabolic Diseases
- Trial name
- cold air (NCT00686491)
- Where
- Canada
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Laval University
Asthma
Bronchoscopy With Bronchial Biopsies Sub-study of: Persistence of Airway Inflammation and Remodeling in Asthma Remission
This study aims at determining the patterns of asthma remission, the prevalence of these different patterns and the various factors associated with such remissions and possible recurrences of asthma, in order to determine the…
- Trial name
- NCT00526344
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Laval University