Clinical trials: sponsored by Laval University
Non-specific Low Back Pain
Effectiveness of Motorised Lumbar Support for Non-specific Low Back Pain
Low back pain (LBP) represents a common musculoskeletal conditions worlwide, causing substantial disability and economic burden.
- Trial name
- NCT07366827
- Testing
- Motorized lumbar support, Standard lumbar support
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Laval University
Cardiac Arrest (CA), Cardiogenic Shock
Evaluation of Acid-base Disorders and Ventilation Settings in Cardiogenic Shock and Post-cardiac Arrest Patients: Comparison With VentilO Algorithm
This study aims to better understand how mechanical ventilation settings affect patients admitted to the coronary care unit after cardiac arrest or with cardiogenic shock.
- Conditions
- Cardiac Arrest (CA), Cardiogenic Shock, Mechanical Ventilation, Acid Base Disorder
- Trial name
- VentilO CU (NCT07484828)
- Testing
- Initiation of mechanical ventilation
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Laval University
Overweight/Obesity, Metabolic Syndrome
Effects of Cranberry on Gut and Metabolic Health
The consumption of plant-based foods, particularly berries, has been associated with improved health due to their high content of bioactive compounds.
- Conditions
- Overweight/Obesity, Metabolic Syndrome, Insulin Resistance, Microbiota
- Trial name
- CRANOS (NCT07460856)
- Testing
- Cranberry beverage
- Where
- Canada
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Laval University
COPD Exacerbation, Pneumonia
Comparison of Multiple Oxygenation Targets With Different Oximeters in Chronic Obstructive Pulmonary Disease (COPD) and Non-COPD Patients- Impact on Oxygen Flows
The oximeter is an instrument for monitoring patients receiving oxygen therapy. It displays pulse oxygen saturation (SpO2), which is a reflection of arterial oxygen saturation (SaO2).
- Conditions
- COPD Exacerbation, Pneumonia, Hypoxemia, Respiratory Disease
- Trial name
- NCT05819164
- Testing
- Masimo oximeter, Nellcor oximeter, Nonin oximeter
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Laval University
Oxygen Delivery, Acute Respiratory Failure
Comparison of Two SpO2 Targets With Two Different Oximeters - Impact on FiO2 During Nasal High Flow Oxygen Therapy
Several factors can influence oxygenation monitoring and respiratory support through oxygen therapy: the type of oximeter used, skin pigmentation, and the oxygenation target.
- Conditions
- Oxygen Delivery, Acute Respiratory Failure, High Flow Oxygen Therapy, Hypoxemic Acute Respiratory Failure
- Trial name
- NCT07168213
- Testing
- Manual FiO2 titration with Philips oximeter (SpO2 target 90%), Manual FiO2 titration with Nonin oximeter (SpO2 target 90%), Manual FiO2 titration with Philips oximeter (SpO2 target 94%)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Laval University
Mechanical Ventilator Care
Measurement of Expiratory Gas Temperature in Intubated Patients to Estimate Expiratory Absolute Humidity
Adequate humidification is essential for intubated patients because dry medical gases can cause thick secretions and dangerous endotracheal tube blockages.
- Trial name
- NCT07420673
- Testing
- Expiratory gases temperature
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Laval University
Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay, Spastic Paraplegia 7
Effects of a Supervised Rehabilitation Program on Disease Severity in Spastic Ataxias
Spastic ataxias are a group of diseases causing symptoms such as walking difficulties and balance impairments that lead to a high risk of falls. No pharmacological treatments exist to treat these diseases.
- Trial name
- NCT06261424
- Testing
- IMPACT - rehabIlitation prograM for sPAstiC aTaxias
- Where
- 5 sites in Canada
- Volunteers
- 84 people
- Sponsor
- Laval University
Low Back Pain, Recurrent
Efficacy of Two Physiotherapy's Approaches in Chronic Low Back Pain: Is Addressing Psychosocial Factors Beneficial?
Low back pain is presently the first cause of disability worldwide. The most recommended interventions by clinical guidelines are exercises and cognitive behavioral therapy although the effect is modest.
- Trial name
- NCT04979403
- Testing
- Physiotherapy
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Laval University
Healthy Eating
Eating Fruits and Vegetables With Pleasure!
The objective of this interventional study is to pilot test a newly evidence-based intervention integrating different dimensions of eating pleasure to promote the consumption of fruits et vegetables.
- Trial name
- PLAISIR (NCT07387289)
- Testing
- Eating fruits and vegetables with pleasure!
- Where
- Canada
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Laval University
Charcoal, Decontamination, Poisoning
Activated CHARcoal in Poisoned Patient - Pilot Trial
The goal of this clinical pilot trial is to determine the feasibility of the clinical trial. Then the large-scale CHARPP will be conducted in order to determine the efficacity of activated charcoal as a treatment for acute…
- Trial name
- CHARPP-Pilot (NCT05471479)
- Testing
- Activated Charcoal, No activated charcoal
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Laval University
Low Back Pain
Effect of Thermal Therapy and Exercises on Acute Low Back Pain
Low back pain (LBP) ranks among the first diseases in term of years lived with disability. The latest Clinical Guideline from the American College of Physicians for acute LBP recommends to select "nonpharmacologic treatment with…
- Trial name
- NCT03986047
- Testing
- Thermal care, Exercises, Education for the management of acute low back pain
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Laval University
Chronic Low-back Pain (cLBP)
Combining Brain Stimulation and Physiotherapy for the Management of Chronic Low Back Pain
Chronic low back pain (CLBP) is a major health challenge in Canada, leading to substantial disability and socioeconomic burden, particularly among Veterans. In military Veterans, LBP is the most common chronic pain condition.
- Trial name
- NCT06999772
- Testing
- Active rTMS, Psychologically-informed physiotherapy (PiP), Usual physiotherapy
- Where
- 2 sites in Canada
- Volunteers
- 96 people
- Sponsor
- Laval University
Hepatitis B
Immunogenicity of 2 Versus 3 Doses of Combined Hepatitis B Vaccines in 2-18 Months Old Children
The main objective of this study is to compare the immunogenicity of the hepatitis B component in children vaccinated with (I) two doses of Infanrix-hexa administered at 2 and 12 months of age versus (II) one dose of…
- Trial name
- NCT04294433
- Testing
- Infanrix-hexa, Infanrix-hexa and Twinrix Junior
- Where
- 2 sites in Canada
- Volunteers
- 431 people, healthy volunteers welcome
- Sponsor
- Laval University
Insomnia Disorder, Insomnia
Cultural Adaptation of CBTi for the Arab World
The goal of this clinical trial is to learn whether culturally adapted versions of Cognitive Behavioral Therapy for insomnia (CBTi) can reduce insomnia severity and improve sleep and mood outcomes in Arab adults with insomnia.
- Conditions
- Insomnia Disorder, Insomnia, Cultural Adaptation
- Trial name
- NCT07337369
- Testing
- Surface+deep level adaptations, Surface level adaptation
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Laval University
Employee Well-being, Work-related Outcomes
Effectiveness of a Multi-Modal Workplace Rest Cabin on Worker Well-Being
This study examines whether access to a rest cabin in the workplace supports employee well-being. Employees of a Canadian insurance company are randomly assigned to one of two groups: immediate access to the rest cabin or a…
- Trial name
- RECHARJME-RCT (NCT07322354)
- Testing
- Recharjme Multi-Modal Rest Cabin
- Where
- 4 sites in Canada
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Laval University
Diabetes, Mellitus, Type 1
A Study About Patient Decision Aids Designed to Help Parents and Guardians in Canada Make Evidence-informed, Values-congruent Decisions About Screening Children for Type 1 Diabetes and Follow-up Decisions.
This study will design and test patient decision aids to help parents and guardians in Canada make decisions about screening their children for type 1 diabetes.
- Trial name
- NCT07317973
- Testing
- Web-based patient decision aid, Standard materials
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Laval University
Type 1 Diabetes (T1D)
CommuniT1D: A Customized Virtual Peer Support Program For People Living With Type 1 Diabetes In Canada
When you live with type 1 diabetes (T1D), it is easy to feel alone. Managing your own T1D or your child's T1D takes constant effort that is invisible to most people.
- Trial name
- NCT07317986
- Testing
- Peer support meetings
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Laval University
Rotator Cuff Related Shoulder Pain
Optimizing the Use of Virtual Reality in Rehabilitation for Individuals With Persistent Shoulder Pain
The primary objective of this clinical trial is to investigate the effect of a block of four specific virtual reality (VR) exercises on upper limb function, pain, kinesiophobia, and pain catastrophizing in individuals with…
- Trial name
- NCT07293312
- Testing
- Virtual reality unimanual distraction task, Virtual reality bimanual distraction task, Virtual reality unimanual reaching tasks with augmented visual feedback
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Laval University
Bariatric Surgery Candidate, Diabetes
Surgery Versus Best Medical Management for the Long Term Remission of Type 2 Diabetes and Related Diseases (REMISSION)
Bariatric surgery procedures induce weight loss through restriction and/or malabsorption. The mechanisms underlying type 2 diabetes remission and others metabolic improvements after Roux-en-Y Gastric Bypass (RYGB), sleeve…
- Trial name
- REMISSION (NCT02390973)
- Testing
- Sleeve Gastrectomy, Roux-en-Y Gastric Bypass, Biliopancreatic Diversion with Duodenal Switch
- Where
- Canada
- Volunteers
- 408 people
- Sponsor
- Laval University
Obesity, Obesity, Morbid
Management of Sleeve Gastrectomy Failure Using Single-anastomosis Metabolic Surgery
Sleeve gastrectomy (SG) has become the most commonly performed weight loss surgery, accounting for 60% of all bariatric operations worldwide.
- Trial name
- NCT05242835
- Testing
- Standard duodenal switch, Single-anastomosis duodenal switch
- Where
- Canada
- Volunteers
- 151 people
- Sponsor
- Laval University