Clinical trials: sponsored by Laval University
Ischemic Heart Disease, Angina Pectoris
Physiology and Residual Ischemia After Percutaneous Coronary Intervention
Despite optimal angiographic result after stent implantation, a number of patients will undergo repeat angiography within 1 year of index procedure.
- Conditions
- Ischemic Heart Disease, Angina Pectoris, Chest Pain, Coronary Artery Disease
- Trial name
- EASY-PRIPCI (NCT04494750)
- Where
- Canada
- Volunteers
- 260 people
- Sponsor
- Laval University
Food Selection
Measurement of Greenhouse Gas Emissions From Meals of a University Food Operator
Université Laval wishes to raise awareness among students and employees in the university community so that they become aware of the impacts of their consumption choices by equipping them to adopt consumption behaviours that are…
- Trial name
- Cafeteria (NCT04152785)
- Testing
- Information regarding GHG and/or nutrition
- Where
- Canada
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Laval University
Mitral Valve Insufficiency
Determinants of the Progression and Outcome of Mitral Regurgitation
Mitral regurgitation (MR) is one of the most frequent valve lesions, both in North America and in Europe, and its prevalence is increasing with the aging of the population.
- Trial name
- PROGRAM (NCT01835054)
- Testing
- Blood biomarkers, DNA collection, Echocardiography
- Where
- 4 sites in Belgium, Canada and 1 more
- Volunteers
- 440 people
- Sponsor
- Laval University
Interstitial Lung Disease
Clinical Impact of HOME Oxygen SATURation Measurement (SATURHOME)
The use of saturometry at home is more and more widespread in patients suffering from interstitial pulmonary diseases (IPD), the patients seeing it as reassurance and a concrete way to follow the evolution of their disease.
- Trial name
- SATURHOME (NCT04624191)
- Testing
- Saturation at home
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Laval University
Aortic Valve Stenosis
Metabolic Determinants of the Progression of Aortic Stenosis
Calcific aortic stenosis (AS) has become the most common cardiac disease after coronary artery disease and hypertension. Unfortunately no medical therapies have been proven to decrease either the progression of valve stenosis or…
- Trial name
- PROGRESSA (NCT01679431)
- Testing
- Doppler-echocardiography, Computed tomography, Magnetic resonance imaging
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Laval University
Aortic Valve Stenosis
Multicenter Prospective Study of Low-Flow Low-Gradient Aortic Stenosis (TOPAS Study)
Low-flow, low-gradient (LF-LG) aortic stenosis (AS) may occur with depressed (i.e. Classical LF; CLF) or preserved (i.e. Paradoxical LF; PLF) LV ejection fraction (LVEF) and both situations are amongst the most challenging…
- Trial name
- NCT01835028
- Testing
- Echocardiography, Computed tomography, Magnetic resonance imaging
- Where
- 11 sites in United States, Austria and 4 more
- Volunteers
- 320 people
- Sponsor
- Laval University
Lung Cancer
Randomized Study of Preoperative Dexamethasone for Quality of Recovery in VATS Lung Resection Patients
The proposed study is a randomized, double-blind, placebo-controlled evaluation if a small dose of IV dexamethasone during induction anesthesia in association to pre and postoperative intercostal nerve block, improves quality of…
- Trial name
- APV (NCT02275702)
- Testing
- Dexamethasone IV, Saline solution
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Laval University
Gut Microbiota, Metabolic Syndrome
Effect of Mango on Gut Microbiota and Metabolic Health
Mango is rich in bioactive compounds such as dietary polyphenols and carotenoids, which may explain its beneficial effect on health. Polyphenols accumulate in the gut where they can positively modulate the microbiota.
- Trial name
- NCT03825276
- Testing
- Mango consumption
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Laval University
Prediabetes, Insulin Resistance
Pilot Study on Metabolic Effects of Fish Peptides and Vitamin D
The overall goal of this study is to investigate the effects and the mechanisms of action of a fish peptide and vitamin D on glucose metabolism, insulin secretion, and cardiometabolic risk profile in overweight men.
- Trial name
- BONITO (NCT02668159)
- Testing
- Fish peptide supplement, Vitamin D supplement, Fish peptide + Vitamin D3 supplements
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Laval University
Obesity, Body Weight
Effects of Capsimax on Appetite, Energy Intake and Blood Pressure
Obesity is an ongoing major public health problem in most countries of the world for which the agrifood industry still remains criticized because of the abundant offer of high sugar-lipid-energy dense foods, particularly in the…
- Conditions
- Obesity, Body Weight, Weight Loss, Overweight
- Trial name
- NCT04874701
- Testing
- Capsimax, Energy restriction
- Where
- Canada
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Laval University
Interstitial Lung Disease
Diagnostic Yield of Transbronchial Cryobiopsy in Diagnosis of Interstitial Lung Diseases
Evaluation of diagnostic yield, feasibility and safety of transbronchial lung cryobiopsies done via bronchoscopy in the investigation of interstitial lung disease in comparison with videothoracoscopy-assisted surgical lung biopsy.
- Trial name
- NCT02235779
- Testing
- Transbronchial lung cryobiopsy
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Laval University
Diet Habit, Microbial Colonization
Effect of Diet on the Microbiota / Endoccanabinoidome Axis in Response to Physical Activity
Both the endocannabinoid system and the microbiome are highly conditioned by nutrition and physical activity, and have an interdependent, bidirectional relationship.
- Conditions
- Diet Habit, Microbial Colonization, Activity, Motor
- Trial name
- PerOME (NCT04766528)
- Testing
- 3 maximal aerobic tests
- Where
- Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Laval University
Contraception
Spermicidal Efficacy Of A Vaginal Gel
There is an urgent need to develop non-hormonal innovative preventive measures under the control of women that can prevent unintended pregnancy.
- Trial name
- NCT03833115
- Testing
- vaginal gel containing or not sodium lauryl sulfate
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Laval University
Hypotension, Anesthesia; Adverse Effect, Spinal and Epidural
ONDANSETRON AND EFFECTIVE DOSE IN 50% OF SUBJECTS OF PROPHYLACTIC NOREPINEPHRINE INFUSIONS FOR PREVENTING SPINAL ANESTHESIA-INDUCED HYPOTENSION DURING CESAREAN DELIVERY
Spinal anesthesia is the preferred technique for elective cesarean section as per ASA guidelines. Hypotension is the main complication of this technique and is secondary to both sympatholysis and its associated decrease in…
- Conditions
- Hypotension, Anesthesia; Adverse Effect, Spinal and Epidural, Cesarean Section
- Trial name
- NCT04703088
- Testing
- Ondansetron 4 MG, 0.9% Saline
- Volunteers
- 60 people
- Sponsor
- Laval University
COVID19, Tailored Recommendations
Optimization of the Management of COVID-19 Through Tailored Recommendations to the Citizens
People with chronic diseases including atherosclerotic heart disease, high blood pressure and diabetes are considered as a group with a high vulnerability.
- Conditions
- COVID19, Tailored Recommendations, Citizen Self-reported Symptoms
- Trial name
- VIGIE-COVID (NCT04699851)
- Testing
- Tailored recommendations, General recommendation
- Where
- Canada
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Laval University
Asthma
Follow-up of Mild Eosinophilic Asthma
Asthma is a chronic respiratory disease affecting approximately 10% of the population, the majority of patients with very mild to mild asthma.
- Trial name
- NCT04650503
- Testing
- No intervention
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Laval University
Parkinson Disease, Mild Cognitive Impairment
Goal Management Training for Parkinson Disease Mild Cognitive Impairment
Mild cognitive impairment is experienced by approximately 30% of patients with Parkinson's disease (PD-MCI), often affecting executive functions.
- Trial name
- NCT04636541
- Testing
- Goal Management Training, Psychoeducation
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Laval University
Panic Disorder, Generalized Anxiety Disorder
Physical and Psychological Health Trajectories in the Context of Coronary Heart Disease
The primary aim of this study is to establish how frequently patients with coronary artery disease present or develop two anxiety disorders (panic disorder and generalized anxiety disorder) in the two years following a medical…
- Conditions
- Panic Disorder, Generalized Anxiety Disorder, Coronary Artery Disease, Anxiety Disorders
- Trial name
- NCT04433832
- Where
- Canada
- Volunteers
- 3,610 people
- Sponsor
- Laval University
Hypertension
Lifestyle Intervention for Treating Systemic Hypertension in Primary Care Setting
The Canadian hypertension education program recommends increased physical activity, adoption of the Dietary Approaches to Stop Hypertension (DASH) diet, and reduction in sodium and alcohol intake for treatment and prevention of…
- Trial name
- NCT02492035
- Testing
- Lifestyle intervention
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Laval University
COPD, Spirometry
Evaluation of a Mobile Application to Facilitate the Interpretation of Spirometry by Family Physicians and Residents
Problematic: Spirometry is used to objectify the obstructive syndrome defining chronic obstructive pulmonary disease (COPD). However, this test remains underused in the primary care.
- Conditions
- COPD, Spirometry, Mobile Application
- Trial name
- NCT03206606
- Testing
- SPIRO
- Where
- 8 sites in Canada
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Laval University