Clinical trials: sponsored by Linkoeping University
Perioperative/Postoperative Complications, Risk Factor, Cardiovascular
Myocardial Injury in Noncardiac Surgery in Sweden
The purpose of this multicentre, prospective, observational study is to identify robust biochemical markers that predict adverse cardiovascular outcomes and mortality in patients undergoing major abdominal surgery.
- Trial name
- MINSS (NCT03436238)
- Where
- 7 sites in Sweden
- Volunteers
- 1,269 people
- Sponsor
- Linkoeping University
Septic Shock, Sepsis
Sepsis in the ICU-II
Sepsis-induced cardiac dysfunction (SIMD) is a well-known phenomenon yet its diagnosis remains elusive with no accepted definition, or defining pathophysiological mechanism associated with this disease.
- Conditions
- Septic Shock, Sepsis, Cardiomyopathies, Organ Failure, Multiple
- Trial name
- NCT04695119
- Testing
- Exposure is septic shock (defined according to Sepsis-III) and standard treatment according to departmental protocols.
- Where
- 4 sites in France, Sweden
- Volunteers
- 379 people
- Sponsor
- Linkoeping University
COVID-19, Critical Illness
Characteristics and Outcomes of Patients Admitted to Swedish Intensive Care Units for COVID-19
This is a registry-based cohort study of all adult patients (≥18 years) admitted to Swedish Intensive Care Units with confirmed SARS-CoV-2 infection and COVID-19 disease during the first 2 months of the 2020 pandemic.
- Trial name
- NCT04462393
- Testing
- Admission to ICU for COVID-19
- Where
- Sweden
- Volunteers
- 7,500 people
- Sponsor
- Linkoeping University
Cardiovascular Diseases
Effects of Exergaming to Reduce Sedentary Time in Inactive Patients With Heart Failure
The goal of this to determine the effect of tailored exergaming for inactive patients with heart failure to reduce their sedentary time, improve their daily physical activity, exercise capacity, decrease frailty and improve…
- Trial name
- Heart-eXg (NCT05641662)
- Testing
- Heart Farming
- Where
- 12 sites in Portugal, Slovakia and 2 more
- Volunteers
- 750 people
- Sponsor
- Linkoeping University
Cancer
Medical YOga dUring CANcer Treatment in a Digital or Physical Setting - a PREFERensbased Study
To enhance the implementation of yoga in cancer care, studies that explore patients with cancer preferences for the execution of yoga, effects, and the experience of participating in group yoga sessions online compared to…
- Trial name
- YouCanPrefer (NCT06248450)
- Testing
- Medical yoga
- Where
- Sweden
- Volunteers
- 163 people
- Sponsor
- Linkoeping University
Heart Failure With Reduced Ejection Fraction
Digital Support Program for Patients With Heart Failure - a Cluster-Randomized Hybrid Type 2 Study
The overall aim of this project is to evaluate the effects of a digital support program for patients with heart failure through a cluster-randomized controlled trial, and to investigate the outcomes of different implementation…
- Trial name
- NCT07275931
- Testing
- Tailored implementation support
- Where
- Sweden
- Volunteers
- 240 people
- Sponsor
- Linkoeping University
Nutrition Poor, Overweight and Obesity
Nutrition Care in Patients Living With Chronic Pain
The investigators' purpose is to develop and test the feasibility, usability, and satisfaction of the Diet4painrelief app as a platform for implementing nutrition care in a specialist pain rehabilitation clinic.
- Conditions
- Nutrition Poor, Overweight and Obesity, Mobile Phone Use, Pain, Chronic
- Trial name
- NCT06277232
- Testing
- Nutrition care, Dialogue and education (part of Interdisciplinary Pain Rehabilitation Program), activity training (part of Interdisciplinary Pain Rehabilitation Program)
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Linkoeping University
Depression and Anxiety Symptom
ICBT for Psychological Symptoms Related to Economy
This study aims to investigate the effects of guided internet-based cogitive behavioral therapy (ICBT) on psychological symptoms related to economy.
- Trial name
- NCT07391540
- Testing
- Internet-based cognitive behavioral therapy
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Linkoeping University
Childhood Cancer, Depressive Symptoms
Cultivating Resilience in Oncology Practice
The purpose of the CROP study is to investigate the potential to cultivate psychological resources and resilience in childhood cancer patients and their family members using a mobile phone-based intervention.
- Conditions
- Childhood Cancer, Depressive Symptoms, Anxiety Disorders and Symptoms, Mental Health Issue
- Trial name
- CROP (NCT04902313)
- Testing
- Awareness and insight Modules (AiM)
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Linkoeping University
Knee Osteoarthritis
Pre-Operative Exercise Therapy and Patient Education Before Total Knee Replacement
The goal of this multi-center randomized controlled trial is to investigate the effect of pre-operative exercise therapy and education for patients awaiting knee replacement surgery on subjective knee function, patient…
- Trial name
- PROTEKT (NCT06290336)
- Testing
- Pre-operative exercise therapy and education, Standardized pre-operative information session
- Where
- Sweden
- Volunteers
- 110 people
- Sponsor
- Linkoeping University
Hypertension, Primary Aldosteronism
Genetic Predisposition to High Blood Pressure
Primary aldosteronism (PA) is a known but underdiagnosed cause of high blood pressure. It is estimated that more than 10% of all people with high blood pressure (HT) suffer from PA, which is often caused by aldosterone-producing…
- Conditions
- Hypertension, Primary Aldosteronism, Genetic Predisposition to Disease
- Trial name
- NCT07181213
- Testing
- Adrenalectomy
- Where
- Sweden
- Volunteers
- 76 people
- Sponsor
- Linkoeping University
Skin Cancer
Artificial Intelligent Decision Support for Skin Cancer Diagnostics in Primary Care
Background: Artificial intelligence has in numerous studies shown high accuracy in detecting skin cancer when trained on various databases of dermatoscopic images.
- Trial name
- AI-DSSC (NCT06932172)
- Testing
- Artificial inteligence based decision support to detect skin cancer
- Where
- 8 sites in Sweden
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Cardiopulmonary Exercise Test, End-Tidal Carbon Dioxide
Test-Retest Reliability And Validation For End-Tidal Carbon Dioxide Measurement (PetCO2) During Rest And Low-Loaded Steady State Work Using A Portable Capnograph.
The goal of this observational study is to investigate exhaled carbon dioxide measuring during rest and low-loaded work using a portable device (capnograph) and standard of care apparatus during a cardiopulmonary exercise test…
- Conditions
- Cardiopulmonary Exercise Test, End-Tidal Carbon Dioxide, VO2max, Ventilatory Physiology
- Trial name
- NCT07326449
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Linkoeping University
Depression Symptoms, Anxiety Symptoms
ICBT for Psychological Symptoms Related to the COVID-19 Pandemic Remaining After Societal Opening
This study aim to investigate the effects of internet-based cognitive behavioral therapy (ICBT) addressing psychological symptoms related to the COVID-19 pandemic and its consequences that remain after societal opening.
- Trial name
- PCC (NCT05656430)
- Testing
- Internet-based Cognitive Behavioral Therapy
- Where
- Sweden
- Volunteers
- 24 people
- Sponsor
- Linkoeping University
NAFLD
NAFLD in Diabetes Type 2 in Primary Care
The EPSONIP (Evaluating Prevalence and Severity Of NAFLD In Primary care) trial is a longitudinal cohort study of patients with T2DM recruited from primary health care centers in Östergötland, Sweden.
- Trial name
- EPSONIP (NCT03864510)
- Where
- 2 sites in Sweden
- Volunteers
- 317 people
- Sponsor
- Linkoeping University
Severe Obesity, Sleeve Gastrectomy
Longitudinal Retrospective Analysis of Prospectively Collected Data for Outcomes After Primary Sleeve Gastrectomy (N=20 000) in the Swedish National Quality Registry SOReg (Scandinavian Obesity Surgery Registry)
The main questions to answer are: Weight outcomes in weight strata over time? What was the proportion of patients reaching sufficient weight outcome in different weight strata? To what extent are co-morbid conditions improved or…
- Trial name
- SCAN (NCT07280845)
- Where
- Sweden
- Volunteers
- 19,977 people
- Sponsor
- Linkoeping University
Depressive Symptoms
The Purpose of the Study is to Investigate if a Smartphone App Combined With Internet Based Cognitive Behavioural Therapy (ICBT) Leads to Improved Symtoms in Depressive Adults on Antidepressive Medicine, Compared to a Wait-list Control Condition
The purpose of the study is to investigate if a smartphone app combined with internet delivered cognitive behavioural therapy (ICBT) leads to improved symptoms in depressive adults on antidepressive mediation.
- Trial name
- FIG (NCT06907134)
- Testing
- Smartphone delivered internet-based Cognitive Behavioural Therapy
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Linkoeping University
Frailty, Ageing Well
Healthy Older Adults Through Movement and Engagement
The HOME Project evaluates the effects of structured health dialogues with individuals aged 67-84 years in the municipality of Borgholm, Sweden.
- Conditions
- Frailty, Ageing Well, Prevention Intervention, Health Related Quality of Life
- Trial name
- HOME (NCT07136168)
- Testing
- Health dialogue
- Where
- Sweden
- Volunteers
- 2,952 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Type 2 Diabetes
DIgitAl diabeTES Treatment - the Healthy Eating, heaLthy Patients Trial
This randomized controlled trial will assess the impact of the FoodSwitch mobile app, which provides interpretive front-of-pack labelling via barcode scanning, in 900 Swedish adults with type 2 diabetes.
- Trial name
- DIATEST-HELP (NCT05977218)
- Testing
- FoodSwitch
- Where
- Sweden
- Volunteers
- 900 people
- Sponsor
- Linkoeping University
Occupational Health
Systematic Health-promoting Work Environment Management in Dentistry
Research shows that the workplace is an important arena where much can be done to promote a sustainable working life while maintaining health.
- Trial name
- NCT06343675
- Testing
- There is no intervention
- Where
- Sweden
- Volunteers
- 732 people, healthy volunteers welcome
- Sponsor
- Linkoeping University