Clinical trials: sponsored by Lund University
Asphyxia Neonatorum, Resuscitation
Effects of Delayed Cord Clamping During Resuscitation of Newborn Near Term and Term Infants
This study evaluates resuscitation with an intact umbilical cord compared to resuscitation with the umbilical cord cut. Half of the newborn babies in need of resuscitation will be handled while having an intact umbilical cord and…
- Trial name
- SAVE (NCT04070560)
- Testing
- Intact cord (≥ 180 seconds) resuscitation, Early (≤ 60 seconds) cord clamping
- Where
- 3 sites in Sweden
- Volunteers
- 600 people
- Sponsor
- Lund University
Back Pain, Neck Pain
WorkUp. Structured Care With Workplace Interventions to Improve Work Ability in Patients With Neck and/or Low Back Pain
WorkUp is a prospective cluster randomised controlled trial in primary care. The main purpose is to investigate effects of early structured care based on screening of red flags (signs of serious medical conditions/disease)…
- Trial name
- WorkUp (NCT02609750)
- Testing
- Structured care & workplace intervention, Treatment as Usual
- Volunteers
- 364 people
- Sponsor
- Lund University
Diabetes Type 2
Arabinoxylan-oligosaccharides (AXOS) for the Management of Type-2 Diabetes
The project aims to achieve significantly improved clinical care for type 2 diabetes. The current standard treatment metformin has low adherence due to its main side effect gut dysbiosis, which also results in more complications…
- Trial name
- NCT05689684
- Testing
- AG+XOS+AXOS
- Where
- Sweden
- Volunteers
- 66 people
- Sponsor
- Lund University
Mental Disorders
Study of Mindfulness-based Group Treatment in Patients With Depression and Anxiety
The purpose of this study is to determine the effectiveness, with respect to symptoms and systemic inflammatory level, of mindfulness-based group treatment compared with normal treatment in patients diagnosed with minor to…
- Trial name
- NCT01476371
- Testing
- Mindfulness-based group treatment
- Volunteers
- 215 people
- Sponsor
- Lund University
Head and Neck Neoplasms, Radiotherapy; Complications
The Impact of Dental Health on Complications During and Following Radiotherapy in the Head and Neck Region.
Study the risk of complications after dental extractions in patients recieving radiotherapy.
- Conditions
- Head and Neck Neoplasms, Radiotherapy; Complications, Extracting Own Teeth
- Trial name
- NCT06840639
- Testing
- Dentoalveolar surgery
- Where
- Sweden
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Lund University Hospital
Quality of Life
A Municipality Implemented Behavioural Intervention to Improve Quality of Life Among Older Adults
Ageing is associated with circadian rhythm sleep disorders, poor sleep at night, less physical activity and more time spent indoors, affecting the wellbeing of older adults.
- Trial name
- NCT06807060
- Testing
- 'Light, activity and sleep in my daily life' intervention
- Where
- 4 sites in Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lund University
End Stage Kidney Disease (ESRD)
Novel Combined Function Test for Patients on Peritoneal Dialysis
Peritoneal membrane function tests such as the traditional peritoneal equilibrium test (PET) aid in the assessment of various peritoneal membrane functions, and are widely used in clinical practice to guide dialysis prescription…
- Trial name
- NCT06723223
- Testing
- Traditional Peritoneal Equilibrium Test, Combined Peritoneal Equilibrium Test
- Where
- Sweden
- Volunteers
- 34 people
- Sponsor
- Lund University
Cesarean Section Complications, Vital Signs Monitoring
Wireless Physiologic Monitoring After Cesarean
With over 18.5 million procedures performed worldwide and increasing, Cesarean section (CS) is the commonest surgical procedure.
- Conditions
- Cesarean Section Complications, Vital Signs Monitoring, Maternal Health Care
- Trial name
- WIP (NCT06654115)
- Testing
- Wireless Physiologic Monitoring
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Lund University
Graves Ophthalmopathy, Thyroid Associated Ophthalmopathy
Treatment of Graves´ophthalmopathy with Simvastatin (GO-S)
In an investigator initiated multicenter trial (Malmö, Odense, Århus) the investigators aim at evaluating activity of Graves´ophthalmopathy (GO) and progress to severe GO in patients with mild to moderate Graves´ ophthalmopathy…
- Conditions
- Graves Ophthalmopathy, Thyroid Associated Ophthalmopathy, Thyroid Associated Orbitopathy
- Trial name
- NCT03131726
- Testing
- Simvastatin 40mg
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Lund University
Exercise, Children
Long-term Exercise Effects from Robotic Walking
The vision of the Long-term Exercise Effects from Robotic Walking (LEER) research program is to develop optimal, individualized exercise strategies that would in turn enhance the health and well-being of non-ambulatory children…
- Conditions
- Exercise, Children, Cerebral Palsy
- Trial name
- LEER (NCT04307602)
- Testing
- Exercise - High Intensity Interval Training (HIIT), Exercise - Submaximal Steady State Training (SST)
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lund University
Head and Neck Squamous Cell Carcinoma
a Multicentre Phase III Study of Risk-based Treatment Intensification With Hyperfractionated Radiotherapy in Head and Neck Cancer Patients
There is an unmet need to personalise treatment for patients with head and neck squamous cell carcinoma (HNSCC) and to improve treatment results for patients with advanced disease.
- Trial name
- ARTSCAN VI (NCT06248996)
- Testing
- Hyperfractionated radiotherpy, Control group
- Where
- 11 sites in Sweden
- Volunteers
- 308 people
- Sponsor
- Lund University Hospital
Arthroscopic Surgery, Temporomandibular Joint
Arthroscopy of the Temporomandibular Joint. On Jaw Mobility, Pain and HRQoL
The aim of the present study is to retrospectively investigate whether arthroscopic treatment in patients with TMD symptoms depending on internal derangement of the temporomandibular joint (TMJ) gives a satisfying result on the…
- Conditions
- Arthroscopic Surgery, Temporomandibular Joint, Health-Related Quality Of Life, Follow-Up Studies
- Trial name
- NCT06433154
- Testing
- Arthroscopic surgery
- Where
- 2 sites in Sweden
- Volunteers
- 127 people
- Sponsor
- Lund University Hospital
Depressive Disorder, Major
Aerobic Group Exercise for Adolescents With Depression
The aim is to evaluate aerobic group exercise versus leisure group activities in adolescents with mild to moderate depression. Primary outcome is Children's Depression Rating Scale - Revised (CDRS-R).
- Trial name
- NCT04695145
- Testing
- Aerobic exercise in group, Group sessions with leisure activities
- Where
- Sweden
- Volunteers
- 14 people
- Sponsor
- Lund University Hospital
Head and Neck Neoplasms, Osteoradionecrosis
Radiation Field, Dose and Fractionation Related to Mandibular Complications
Radiotherapy is inhibiting the healing capacity of the mandibular bone. Late complications as bone exposure, fracture of the jaw, osteoradionecrosis might be a consequence of this vulnerability.
- Conditions
- Head and Neck Neoplasms, Osteoradionecrosis, Radiotherapy; Complications
- Trial name
- NCT05412849
- Testing
- Radiotherapy
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Lund University Hospital
Anterior Cruciate Ligament Injury
Motor Imagery to Facilitate Sensorimotor Relearning After ACL Injury
Anterior cruciate ligament injury is a common issue in sports involving cutting and jumping. Treatment may include surgical intervention followed by physical therapy, or no surgical intervention with the main treatment being…
- Trial name
- MOTIFS (NCT03473821)
- Testing
- MOTIFS
- Where
- Sweden
- Volunteers
- 106 people
- Sponsor
- Lund University
Oral Surgical Procedures, Surgery, Oral
Standardized Osteotomy Guides for Free Flap Reconstruction of Continuous Defects of the Jaws - a Simplified Method
The aim of the present project is to evaluate the outcome from reconstruction of the jaws, with a standardized simplified technique, after a continuous defect.
- Conditions
- Oral Surgical Procedures, Surgery, Oral, Mandibular Reconstruction
- Trial name
- NCT05715359
- Testing
- Reconstruction
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Lund University Hospital
Sport Injury, Ice-Skates Accident
Epidemiology of Injuries in the Professional Women's Swedish National IceHockey League Permitted to Body-Checking
This research project can contribute to a deeper understanding of injury patterns among professional female ice-hockey players allowed to body check.
- Conditions
- Sport Injury, Ice-Skates Accident, Sports Accident, Female Athlete Triad
- Trial name
- NCT06351618
- Testing
- No intervention will be conducted.
- Where
- Sweden
- Volunteers
- 225 people
- Sponsor
- Lund University
Heart Arrest, Out-Of-Hospital, Computed Tomography
Head Computed Tomography for Predicting Neurological Outcome After Cardiac Arrest
The European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM) joint guidelines for post-resuscitation care recommend a multimodal approach to prognostication of neurological outcome.
- Conditions
- Heart Arrest, Out-Of-Hospital, Computed Tomography, Unconsciousness, Neurologic Deficits
- Trial name
- NCT03913065
- Testing
- CT
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Lund University
Cardiac Arrest, Neurological Outcome
Early Neuroprognostication After OHCA
This is a prospective observational substudy of the STEPCARE trial ClinicalTrials.gov Identifier: NCT05564754) with the aim to examine whether prognostication of neurological outcome after cardiac arrest can be performed earlier…
- Conditions
- Cardiac Arrest, Neurological Outcome, EEG, CT
- Trial name
- NCT05706194
- Testing
- Early neurological prognostication with biomarkers, EEG and CT
- Where
- 4 sites in Finland, Germany and 1 more
- Volunteers
- 1,000 people
- Sponsor
- Lund University
Nerve Injury, Peripheral Nerve Injuries
Experience and Feasibility of Methods for Early Sensory Training
The good effects of using guided plasticity for a rehabilitative purpose in case of nerve damage have been shown, but a problem that has been presented is that some individuals find it difficult to assimilate these effects due to…
- Trial name
- NCT05611983
- Testing
- sensory relearning
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Lund University Hospital