Clinical trials: sponsored by Mahidol University
Bloating, Rifaximin
Rifaximin Treatment in Bloating Predominant Functional Bowel Disorders
This randomized, double-blind, placebo-controlled trial will evaluate the effects of a 14-day course of rifaximin on bloating symptoms, gut microbiota, microbial metabolites, and intestinal gases in adults with Rome V irritable…
- Conditions
- Bloating, Rifaximin, Functional Bowel Disorder, Irritable Bowel Syndrome
- Trial name
- NCT07522255
- Testing
- Rifaximin (drug)
- Where
- Thailand
- Volunteers
- 78 people
- Sponsor
- Mahidol University
Diabete Mellitus, Dyslipidaemia
Prevalence and Associated Factors of High BMI and Periodontitis in Thai Adults Aged Under 60 Years
Overweight and obesity, as well as periodontitis, are common public health problems with increasing prevalence. Both conditions may be linked through shared mechanisms involving chronic low-grade systemic inflammation.
- Conditions
- Diabete Mellitus, Dyslipidaemia, Chronic Kidney Disease, Psychiatric Disorder
- Trial name
- NCT07880717
- Testing
- Periodontal Examination, Questionnaire interview, Anthropometric measurements
- Where
- Thailand
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Obstructive Sleep Apnea (OSA)
The Effects of Hypoxic Burden on Executive Function (EF) in Preschool Children With Obstructive Sleep Apnea
The goal of this observational study is to study the effect of hypoxic burden on executive function in preschool children aged 2-6 years who have OSA.
- Trial name
- NCT07023458
- Testing
- Brief-P
- Where
- Thailand
- Volunteers
- 72 people
- Sponsor
- Mahidol University
Healthy
Effects of Different Intensities of Bilateral- and Cathodal Transcranial Direct Current Stimulation in Healthy Individuals
This study will separate study to investigate the effects of 1 mA, 1.5 mA, and 2 mA of 1) bilateral- and 2) cathodal tDCS on cortical activity and motor learning in healthy individuals
- Trial name
- NCT05929014
- Testing
- study 1) Active bilateral-tDCS, study 2) active cathodal-tDCS
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Major Adverse Cardiac Events, Adverse Effect of Unspecified General Anesthetic
Adverse Events in Acute Limb Ischemic Patient Undergoing Revascularization
Acute limb ischemia is one of the devastating vascular emergencies that lead to life and limb loss if the appropriate treatment is not reached.The revascularization is a cornerstone in treating acute limb ischemia.
- Trial name
- NCT05362266
- Where
- 2 sites in Thailand
- Volunteers
- 240 people
- Sponsor
- Mahidol University
Inflammatory Bowel Diseases, Crohn Disease
Intestinal Ultrasound Guided Management in Inflammatory Bowel Disease
This randomized controlled trial evaluates whether adding point-of-care intestinal ultrasound (IUS) to standard of care changes clinical management in patients with inflammatory bowel disease (IBD).
- Conditions
- Inflammatory Bowel Diseases, Crohn Disease, Colitis, Ulcerative
- Trial name
- NCT07775352
- Testing
- Intestinal ultrasound (IUS), Standard of care
- Where
- Thailand
- Volunteers
- 137 people
- Sponsor
- Mahidol University
Healthy Aging, Health Promotion
Cost-Effectiveness Analysis of the Healthy Beat Acupunch Regimen on Physical Fitness, Sleep Quality, and Quality of Life Among Community-Dwelling Older Adults
This study will evaluate the effects and preliminary cost-effectiveness of the Healthy Beat Acupunch (HBA) exercise program among community-dwelling older adults in Thailand.
- Trial name
- NCT07868575
- Testing
- Healthy Beat Acupunch (HBA) Exercise Program
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Vaccine Hesitancy
Dengue Vaccine Hesitancy Among International Travelers
The goal of this cross-sectional study is to study dengue vaccine hesitancy among 390 international travelers who visit the Hospital for Tropical Diseases, Bangkok, and three public sites which are the area near the Grand Palace…
- Trial name
- NCT06418854
- Testing
- Questionnaire
- Where
- Thailand
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Angioplasty, Anaesthesia and Analgesia
Popliteal Block for Lower Limb Angioplasty
Endovascular revascularization is an effective procedure in treatment of chronic critical limb ischemia. The less invasive procedure in high risk patients produce the benefit to the patients.
- Trial name
- NCT04445480
- Testing
- Popliteal block, Control
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Evaluate the Prototype Digital Vaccine Platform
The Evaluation of The Prototype Digital Vaccine Platform "TM-VAX" Among User in The Hospital for Tropical Diseases
RATIONALE: Digital technology plays a key role in modern healthcare, impacting diagnosis, treatment, and health information management.
- Trial name
- NCT06843876
- Testing
- digital vaccine platform "TM VAX" application
- Where
- Thailand
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Hpv
Effectiveness of HPV Vaccine Among Adolescents and Reproductive Women
To assess the effectiveness of HPV vaccine 2 doses or less to prevent HPV high risk infection among adolescents and adults. We conduct the test-negative control study including 12-45 women who interest to do a check-up pap smear.
- Trial name
- NCT06220747
- Where
- 2 sites in Thailand
- Volunteers
- 760 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Postoperative Recovery in Children
Development and Validation of the Paediatric Scale for Quality of Recovery in the Post-Anaesthesia Care Unit
This project aims to develop and test a new questionnaire to measure how well children recover in the post-anaesthesia care unit (PACU).
- Trial name
- PedSQoR-PACU (NCT07610915)
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Mahidol University
Hemorrhagic Stroke, Ischemic Stroke
Changes in Hemodynamic Response Following Transcranial Electrical Stimulation in Sroke Individuals
The present study will use transcranial electrical stimulation (tES) which are transcranial direct current stimulation (tDCS) and transcranial alternating current stimulation (tACS) combined with conventional physical therapy and…
- Conditions
- Hemorrhagic Stroke, Ischemic Stroke, Subacute Stroke, Chronic Stroke Survivors
- Trial name
- NCT07433972
- Testing
- Transcranial direct current stimulation, transcranial alternating current stimulation, Rehabilitation program
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Migraine Disorders, Medication Overuse Headache
Greater Occipital Nerve Block for Migraine With Medication Overuse Headache
Migraine is among the leading causes of disability worldwide. Inappropriate use of acute medications in the setting of primary headache, particularly migraine can result in a debilitating condition known as medication overuse…
- Conditions
- Migraine Disorders, Medication Overuse Headache, Greater Occipital Nerve Block
- Trial name
- GONB_MOH (NCT07568496)
- Testing
- Lidocaine 2% and Methylprednisolone 80 mg
- Where
- 3 sites in Thailand
- Volunteers
- 130 people
- Sponsor
- Mahidol University
Sleep Disturbance, Delirium
Lemborexant for Sleep and Delirium Prevention in Elderly ICU Patients
Sleep disturbance is very common among critically ill patients in the intensive care unit (ICU), particularly in older adults after surgery.
- Conditions
- Sleep Disturbance, Delirium, Critical Illness
- Trial name
- NCT07407400
- Testing
- Lemborexant
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Mahidol University
Edible Insect Allergy, Shrimp Allergy
Shrimp Sensitization and Allergy Among Patients With Edible Insect Allergy
This study aims to determine the prevalence of shrimp sensitization and clinical shrimp allergy among patients aged ≥7 years with confirmed allergy to edible insects, including silkworm, bamboo worm, and palm weevil.
- Conditions
- Edible Insect Allergy, Shrimp Allergy, Shrimp Sensitization
- Trial name
- NCT07857187
- Testing
- Edible Insect Oral Food Challenge, White Shrimp Oral Food Challenge
- Where
- Thailand
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Influenza
Safety and Immunogenicity of GPO Seasonal Tetravalent Inactivated Split Virion Influenza Vaccine in Healthy Thais
The study is aim to evaluate the safety and immunogenicity of one dose TetraFluvac TF vaccine (15 μg HA per strain per dose) of the GPO seasonal quadrivalent inactivated split virion influenza vaccine in healthy adults aged 18…
- Trial name
- NCT05895955
- Testing
- TetraFluvac TF vaccine, Vaxigrip vaccine
- Where
- Thailand
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Pertussis
10-year Follow-up After a Single Dose Acellular Pertussis Vaccination
This is a phase IV, open-label, non-randomized study to demonstrate superior immunogenicity and safety of a second booster dose of Pertagen® as compared to Adacel® at 10 years after the first booster vaccination and to evaluate…
- Trial name
- NCT06803524
- Testing
- Pertagen® vaccine, Adacel® vaccine
- Where
- 2 sites in Thailand
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Tuberculosis (TB), End-Stage Kidney Disease
Evaluation of IGRA, Symptoms and Chest Radiograph for Subclinical TB Detection in ESRD and KT
This is an observational study among approximately 160 end-stage renal disease patients on renal replacement therapy and post-living donor or deceased donor kidney transplant recipients.
- Trial name
- NCT06700876
- Where
- Thailand
- Volunteers
- 160 people
- Sponsor
- Mahidol University
Constipation
Mixed Natural Prebiotic-Fibers Impact on Stool Frequency and Fecal Microbiota in Constipated Thai Adults
Mixed Natural Prebiotic-Fibers Impact on Stool Frequency and Fecal Microbiota in Constipated Thai Adults: A Randomized Clinical Trial.
- Trial name
- NCT06274242
- Testing
- Haruna
- Where
- Thailand
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Mahidol University