Clinical trials: sponsored by Mahidol University
Bullous Dermatoses, Psoriasis
Intradermal Tozinameran for Patients With Immune-mediated Dermatologic Diseases
This is a randomised controlled trial conducted to prove that the immunological performance of intradermal tozinameran (i.e., Pfizer-BioNTech COVID-19 vaccine) is no worse than the standard intramuscular route in patients with…
- Conditions
- Bullous Dermatoses, Psoriasis, COVID-19 Vaccines
- Trial name
- NCT05406908
- Testing
- tozinameran
- Where
- Thailand
- Volunteers
- 109 people
- Sponsor
- Mahidol University
Knee Arthropathy
Comparison of Accuracy and Functional Outcome Between Robotic and Gyroscopic Assisted Surgery in Primary TKA
A randomized controlled trial was conducted with 72 participants who had moderate knee osteoarthritis (Kellgren and Lawrence grade 2-3).
- Trial name
- NCT06321952
- Testing
- ROSA robotic assist TKA, iassist TKA
- Where
- Thailand
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Cryotherapy Effect, Warts
Cost-effectiveness of EndWarts® FREEZE - an Alternative Home Cryotherapy Device for Wart Treatment
This study aimed to study cost-effectiveness of EndWarts® FREEZE for wart treatment, compared to conventional liquid nitrogen cryotherapy
- Trial name
- NCT04781244
- Testing
- EndWarts® FREEZE, Liquid nitrogen
- Where
- Thailand
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Cirrhosis, Hep A
Efficacy and Durability of Hepatitis A Vaccination in Patients With Advanced Fibrosis and Cirrhosis
The hepatitis A virus (HAV) is a significant global public health concern. The hepatitis A virus is transmitted primarily by the faecal-oral route, leading to acute hepatitis.
- Conditions
- Cirrhosis, Hep A, Vaccination
- Trial name
- NCT06277882
- Testing
- HAVRIX
- Where
- Thailand
- Volunteers
- 50 people
- Sponsor
- Mahidol University
Microbial Disease, Metabolomics
Foot-skin Microbiome and Metabolomics of Pitted Keratolysis
This study aimed to investigate the skin microbiome and metabolomics of patients with pitted keratolysis.
- Trial name
- Foot-skin M&M (NCT04781036)
- Testing
- 4%Chlorhexidine
- Where
- 2 sites in Thailand
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Head and Neck Cancer, Locally Advanced
Palbociclib With Cetuximab and IMRT for Locally Advanced Squamous Cell Carcinoma
Cyclin D kinase 4 (CDK4) is a key regulator of the G1-S transition in the cell cycle. Alterations in CDK4-cyclin D-retinoblastoma (Rb) pathway may lead to carcinogenesis in many cancers.
- Trial name
- NCT03024489
- Testing
- Palbociclib, Cetuximab, Intensity Modulated Radiation Therapy
- Where
- Thailand
- Volunteers
- 27 people
- Sponsor
- Mahidol University
SIRS
Efficacy of Intravenous In-line Filter in Patient Undergoing Cardiac Surgery
The aim of this study is to demonstrated efficacy of in-line filtration to reduce systemic inflammatory response syndrome (SIRS) ,specific organ dysfunction and complications in adult cardiac surgery.
- Trial name
- NCT03784521
- Testing
- In-line filtration, Standard care
- Where
- Thailand
- Volunteers
- 486 people
- Sponsor
- Mahidol University
Myocardial Injury
Comparison of Lactated Ringer's Solution and PlasmaLyte-A as a Base Solution for Del Nido Cardioplegia
Del Nido cardioplegia has been used exclusively for myocardial protection in pediatrics cardiac surgery for decades. Its unique properties including lidocaine which helps counteract potassium depolarization of the myocardial cell…
- Trial name
- NCT04051580
- Testing
- Lactated Ringer
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Mahidol University
Depression
Effectiveness of Ketamine Treatment for Three Consecutive Days in Depression
Inclusion criteria: 1. patient over 20 years old with depression diagnosed by a psychiatrist and MADRS >= 25 scores; 2. failed to improve by at least optimal dosage of two antidepressants for four weeks and one psychotherapy.
- Trial name
- NCT05026203
- Testing
- Ketamine Hydrochloride, Midazolam
- Where
- Thailand
- Volunteers
- 24 people
- Sponsor
- Mahidol University
Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
Biomechanics and Clinical Outcomes in Responders and Non-Responders
Knee osteoarthritis is a degenerative joint disease that affects many older adults. However, not all patients see improvements as a result of physical therapy management; therefore, a better understanding of biomechanics and…
- Conditions
- Osteoarthritis, Knee, Arthroplasty, Replacement, Knee, Physical Therapy
- Trial name
- NCT06080763
- Testing
- Physical Therapy Management
- Where
- 2 sites in Thailand
- Volunteers
- 80 people
- Sponsor
- Mahidol University
Type 2 Diabetes, Insomnia
Cognitive Behavioral Therapy for Insomnia in Type 2 Diabetes Mellitus
This study will explore the effects of cognitive behavioral therapy for insomnia (CBTI) compare to health educations in patients with type 2 diabetes (T2DM) with insomnia symptoms.
- Trial name
- NCT06202742
- Testing
- cognitive behavioral therapy for insomnia, Health education
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Surgery-Complications, Nephrolithiasis Staghorn Calculus
Comparison of Total Tubeless Mini-PCNL Versus Tubeless Mini-PCNL
Limited literature has focused on the use of totally tubeless mini-percutaneous nephrolithotomy (Mini-PCNL) for the treatment of large renal stones.
- Conditions
- Surgery-Complications, Nephrolithiasis Staghorn Calculus, Safety Issues
- Trial name
- NCT06288022
- Testing
- total tubeless mini-PCNL, tubeless mini-PCNL
- Where
- Thailand
- Volunteers
- 130 people
- Sponsor
- Mahidol University
Helicobacter Pylori Infection, Peptic Ulcer Hemorrhage
Diagnostic Performance of CIM for Helicobacter Pylori Infection in Patients With Peptic Ulcer Bleeding
The goal of this cross-sectional study is to evaluate the efficacy of current infection marker (CIM) method for H. pylori detection. The main questions it aims to answer are: To evaluate the efficacy of CIM method for H.
- Trial name
- CIM (NCT06273384)
- Where
- Thailand
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Muscle Cramp, Cirrhosis
Effect of Branched-chain Amino Acids (BCAA) to Muscle Cramps in Patients With Cirrhosis
The goal of this randomized controlled trial is to compare the efficacy and safety of branched-chain amino acids (BCAA) versus placebo for treating muscle cramps in cirrhotic patients.
- Conditions
- Muscle Cramp, Cirrhosis, Quality of Life
- Trial name
- NCT05724485
- Testing
- Branched-chain Amino Acid
- Where
- Thailand
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mahidol University
COPD, OSA
Efficacy of CPAP Therapy on Pulmonary Function Test in Patients With COPD-OSA Overlap Syndrome
To evaluate efficacy of CPAP Therapy on Pulmonary Function Test in Patients With COPD-OSA Overlap Syndrome
- Conditions
- COPD, OSA, Lung Function Decreased
- Trial name
- NCT05857475
- Testing
- CPAP therapy, Control
- Where
- Thailand
- Volunteers
- 10 people
- Sponsor
- Mahidol University
Sarcopenia, Cirrhosis, Liver
Daily Step Count Using Pedometer for Sarcopenic Management in Patient With Cirrhosis: Randomized Controlled Trial
The goal of clinical trial is to compare using pedometer in sarcopenic cirrhotic patients. The main questions it aims to answer are: 1.
- Conditions
- Sarcopenia, Cirrhosis, Liver, Daily Step Count
- Trial name
- NCT06231420
- Testing
- Encourage using pedometer, pedometer
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Mahidol University
Thin Endometrium
a-PRP Intrauterine Instillation in Women With Thin Endometrium
This study sought to compare the endometrial thickness among infertile women with a history of thin endometrium together with previous cancellation from IVF/ICSI inspection of intrauterine instillation of autologous-PRP or no…
- Trial name
- PRP(a-PRP) (NCT06234540)
- Testing
- PRP, Standard treatment
- Where
- Thailand
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Laxity; Skin
Efficacy and Safety of Fractional 1064-nm Picosecond Laser for Facial Skin Tightening
The goal of this clinical trial is to learn the efficacy and safety of fractional 1064-nm picosecond laser for facial skin tightening.
- Trial name
- NCT06231914
- Testing
- StarWalker® PQX
- Where
- Thailand
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Post COVID-19 Condition
The Effectiveness of a Health Promotion Program for Older People With Post-Covid-19 Sarcopenia
The goal of this clinical trial is to investigate the prevalence of sarcopenia in older people with post-COVID-19 living in Ratchatewi district, Bangkok and to test the effectiveness of health promotion program for older people…
- Trial name
- Sarcopenia (NCT06211686)
- Testing
- Protein powder and Resistance exercise
- Volunteers
- 50 people
- Sponsor
- Mahidol University
Sleep Disorder, Inflammatory Bowel Diseases
Sleep Disorder in Inflammatory Bowel Disease and Its Association With Disease Activity
Recently, an association between active inflammatory bowel disease (IBD) and poor sleep quality has been proposed; however, the causal relationship has not yet been established.
- Trial name
- NCT05536817
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Mahidol University