Clinical trials: sponsored by Mahidol University
Renal Insufficiency, Cis-Platinum Nephropathy
Safety of Short Hydration Method for Cisplatin Administration Compared With Conventional Hydration
The aim of the study is to evaluate safety of short hydration with cisplatin administration. The main outcome is renal dysfunction following cisplatin use with short hydration protocol.
- Trial name
- NCT05884905
- Testing
- short hydration, conventional hydration
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Mahidol University
Iron Deficiency, Anaemia in Children
Effect of a Dietary Iron Program on Iron Status and IQ in Children in Phatthalung Province, Thailand
Iron deficiency (ID) continues to be one of the most prevalent disorders, which can adversely affect cognitive ability in childhood.
- Trial name
- NCT05878379
- Testing
- Dietary Iron Program
- Where
- Thailand
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Foot Dermatoses
Chlorhexidine Scrub, ZnO Nanoparticles Socks and the Combination for Treatment of Pitted Keratolysis
This study aimed to study the efficacy of chlorhexidine scrub, zinc oxide nanoparticles (ZnO-NPs) socks and the combination of chlorhexidine scrub and ZnO-NPs socks in treatment of pitted keratolysis.
- Trial name
- PK_treatment (NCT04332796)
- Testing
- Chorhexidine scrub, ZnO-NPs socks, Combination of chorhexidine scrub and ZnO-NPs socks
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Surgical Site Infection
Protocol Effect of Negative Pressure Drain to Reducing Surgical Site Infection in Surgical Wound of Abdominal Surgery
Surgical site infection (SSI) is one of main complication in surgery. It usually occurs within 30 days post operation. The superficial SSI is an infection of skin and subcutaneous layer, clinically presented by pus oozing.
- Trial name
- NCT05865821
- Testing
- Negative pressure drainage, No pressure drain
- Where
- Thailand
- Volunteers
- 130 people
- Sponsor
- Mahidol University
Iodine Deficiency
Nutritional Status and Iodized Salt Use Among School-aged Children
To determine and explore the iodized salt concentration provided in the local community, especially in the Phu Kut district whether it meets the standard or not.
- Trial name
- NCT05862376
- Where
- 2 sites in Thailand
- Volunteers
- 367 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Hip Fractures, Pain, Acute
The Impact of Integrated Preoperative Fascia Iliaca Compartment Block in Elderly Hip Fracture
This prospective randomized controlled study is aimed to determine the advantages of post-admission fascia iliaca compartment block (FICB) in geriatric hip fracture surgery combination with multimodal analgesia compared with no…
- Conditions
- Hip Fractures, Pain, Acute, Hip Fracture Surgery, Delirium in Old Age
- Trial name
- NCT05857462
- Testing
- Post-admission FICB
- Where
- Thailand
- Volunteers
- 420 people
- Sponsor
- Mahidol University
Wheat Allergy
Luminex-based Assay to Identify Major IgE-binding Episode Among IgE-mediated Wheat-allergic Patient
This study will be using Luminex-based peptide assay (LPA) to determine major IgE-binding epitope among wheat allergic children to differentiate clinical phenotype.
- Trial name
- NCT04100122
- Testing
- Blood drawing
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Mahidol University
Anesthesia; Adverse Effect, Cesarean Section Complications
Factors Associated With Failed Spinal Anesthesia for Cesarean Delivery
The aim of this study is to reveal the factor associated with failed spinal anaesthesia in cesarean delivery. We conduct the retrospective case-control study to elucidate the involving factors.
- Trial name
- NCT04685980
- Testing
- spinal anaesthesia with local anaesthetic and intrathecal morphine
- Where
- Thailand
- Volunteers
- 440 people
- Sponsor
- Mahidol University
Cesarean Section Complications, Anesthesia Complication
Incidence of Complications Associated With Anesthesia in Obesity Parturient Undergoing Cesarean Delivery
The incidence of obesity parturient has been increasing worldwide. There was a report revealing one third of pregnant women in United state considered obesity.
- Conditions
- Cesarean Section Complications, Anesthesia Complication, Obesity, Morbid
- Trial name
- NCT04657692
- Testing
- Anesthesia; general or regional
- Where
- Thailand
- Volunteers
- 527 people
- Sponsor
- Mahidol University
Colonic Polyp
Intraluminal Peppermint Oil and Adenoma Detection Rate in Screening Colonoscopy
This is a prospective randomized placebo-controlled trial to evaluate the efficacy of peppermint oil spraying into the colonic lumen through the scope channel during screening colonoscopy.
- Trial name
- NCT05559814
- Testing
- Intraluminal peppermint oil
- Where
- Thailand
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Cow Milk Allergy
Growth and Plasma Amino Acids in Infants With CMPA and Treated With a Newly Innovated Amino Acid Formula
The purpose of this study is to determine growth and protein status of infants with cow's milk protein allergy and treated with a newly innovated amino acid formula compared to those with a commercial amino acid formula.
- Trial name
- CMPA (NCT01637688)
- Testing
- Comparison of treatment with different amino acid formulas
- Where
- Thailand
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Fasting
Recommended Clear Fluid Intake Volume at 2 Hours Prior to Esophagogastroduodenoscopy for Adult Patients
Research in developing patient fasting guidelines was developed years ago. On a physiological basis, patients with a longer fasting time may have less residual gastric content and lower risk of pulmonary aspiration.
- Trial name
- NCT04501393
- Testing
- Clear liquid intake
- Where
- Thailand
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Mahidol University
End Stage Renal Disease
Comparison of Efficacy in Removal of Advanced Glycation End Products (AGEs) Between Super High-flux Hemodialysis and Postdilution Online Hemodiafiltration: A Single-center, Prospective, Open-label, Crossover Randomized Controlled Trial
The goal of this clinical trial is to compare efficacy in advanced glycation end products removal between Super high-flux Hemodialysis and high-volume post-dilution online hemodiafiltration.
- Trial name
- NCT05777148
- Testing
- super high-flux hemodialysis, postdilution online hemodiafiltration
- Where
- Thailand
- Volunteers
- 22 people
- Sponsor
- Mahidol University
Pharmacokinetics, Pharmacogenomics
Population Pharmacokinetics and Pharmacogenomics of Oral Oxycodone in Thai Pediatric Surgical Patients
This study is designed as an experimental trial which collect prospective data at Mahidol university. It aims to characterize the responses of Thai pediatric population,age 1 - 6 years, to oxycodone oral syrup and its metabolites…
- Conditions
- Pharmacokinetics, Pharmacogenomics, Oxycodone
- Trial name
- PedPK (NCT03145272)
- Testing
- Oxycodone
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Pulmonary Embolism, Renal Cell Carcinoma
The Incidence of Pulmonary Embolism During Nephrectomy
Patients with renal carcinoma was reported at high incidence of perioperative pulmonary embolism from current study. The investigators aimed to determine the incidence and outcome of this group of patient in the tertiary-care…
- Conditions
- Pulmonary Embolism, Renal Cell Carcinoma, Nephrectomy
- Trial name
- NCT04402749
- Testing
- Nephrectomy
- Where
- Thailand
- Volunteers
- 416 people
- Sponsor
- Mahidol University
Diastolic Dysfunction, Morbid Obesity
Diastolic Dysfunction in Morbidly Obese Patients Undergo Bariatric Surgery
Morbidly obese patients are at risk for diastolic cardiac dysfunction, which can lead to adverse event, such as, diastolic heart failure postoperatively.
- Trial name
- NCT04128735
- Where
- Thailand
- Volunteers
- 116 people
- Sponsor
- Mahidol University
Instability; Back
Neuromuscular Electrical Stimulation and Motor Control
Phase I, this study aims to:- 1. Establish intra- and inter-rater reliability and minimal detectable change of ultrasound imaging measurement 2.
- Trial name
- NCT03786627
- Testing
- Combined NMES and motor control
- Where
- Thailand
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Plantar Fascitis, Fasciitis, Plantar, Chronic
Effectiveness of Strengthening Exercise Program Compare With Foot Orthoses in Patients With Plantar Heel Pain
Plantar heel pain (PHP), normally known as plantar fasciitis, is a common encountered musculoskeletal problem in the foot that can cause activities limitation, difficulty, and discomfort especially while standing and walking.
- Trial name
- NCT05059054
- Testing
- Strengthening exercise, Insole (CFO) group
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Mahidol University
Colorectal Cancer, Colorectal Adenoma
FIT and Fecal Calprotectin in Patients With Chronic Lower GI Symptoms
Chronic lower gastrointestinal (GI) symptoms, including lower abdominal pain, bowel habit change, bleeding per rectum, and abdominal bloating, are caused by functional gastrointestinal disorders (FGID) and organic intestinal…
- Conditions
- Colorectal Cancer, Colorectal Adenoma, Colitis
- Trial name
- NCT05514561
- Testing
- Fecal calprotectin, Fecal immunochemical test
- Where
- Thailand
- Volunteers
- 1,007 people
- Sponsor
- Mahidol University
Tuberculosis, Drug Induced Liver Injury
Efficacy of N-acetylcysteine to Prevent Anti-tuberculosis Drug-induced Liver Injury: A Randomized Controlled Trial
To determine the efficacy of NAC to prevent clinically significant anti-TB drugs induced liver injury (AT-DILI).
- Conditions
- Tuberculosis, Drug Induced Liver Injury, Hepatitis
- Trial name
- NCT05738681
- Testing
- N acetyl cysteine
- Where
- Thailand
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Mahidol University