Clinical trials: sponsored by Mahidol University
Pain, Postoperative
Optimum-pressure for Reducing Postoperative Shoulder-tip Pain in Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy (LC) is the standard treatment of gallbladder disease. LC is the common procedure for general surgeons.
- Trial name
- NCT04212936
- Testing
- Intraabdominal pressure
- Where
- Thailand
- Volunteers
- 84 people
- Sponsor
- Mahidol University
Dengue Hemorrhagic Fever
Pharmacokinetics and Pharmacodynamics of Ivermectin in Pediatric Dengue Patients
Design and Outcomes This research study is designed as open-label, sequential dose-escalating clinical trial. There will be two phases of enrollment.
- Trial name
- PKIDEN (NCT03432442)
- Testing
- Ivermectin
- Where
- Thailand
- Volunteers
- 24 people
- Sponsor
- Mahidol University
Gastric Ultrasound, Learning Curve
Learning Curves of Gastric Ultrasound for Novel
Various studies have shown that gastric sonography can reliably provide information on both qualitative (nature of content) and quantitative (volume) aspects of gastric content.
- Conditions
- Gastric Ultrasound, Learning Curve, Novel in Gastric Ultrasound
- Trial name
- NCT04760106
- Testing
- gastric ultrasound
- Where
- Thailand
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Post Extubation Respiratory Failure, Re-intubation
Efficacy of HFNC Versus NIV for Prevent Reintubation in Sepsis Patients
Post extubation respiratory failure occur in 30% of extubated patients. More than 50% of them required reintubation. Noninvasive positive pressure ventilation (NIV) had been reported as an effective tool to prevent post…
- Conditions
- Post Extubation Respiratory Failure, Re-intubation, Septic Shock, Severe Sepsis
- Trial name
- NCT03246893
- Testing
- Noninvasive positive pressure ventilation, High flow oxygen nasal cannula
- Where
- Thailand
- Volunteers
- 222 people
- Sponsor
- Mahidol University
First Trimester Pregnancy
Comparative Study of Learning Curve for First Trimester Fetal Anomaly Scan
Ultrasound scans during first trimester are more difficult than routine mid-trimester ultrasound scans. Practice guidelines for first trimester fetal ultrasound scans have been provided by the International Society of Ultrasound…
- Trial name
- NCT04707456
- Testing
- Training operator
- Where
- Thailand
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Asymptomatic Infections, SARS-CoV2 Infection
Ivermectin vs Combined Hydroxychloroquine and Antiretroviral Drugs (ART) Among Asymptomatic COVID-19 Infection
This is an open label randomised controlled study of oral ivermectin (600 mcg/kg/d* 3 day) versus combined of hydroxychloroquine plus darunavir/ ritonavir for 5 days treatment among asymptomatic carrier of SAR-CoV2 adult Thai…
- Trial name
- IDRA-COVID19 (NCT04435587)
- Testing
- Ivermectin Pill, Combined ART/hydroxychloroquine
- Where
- 4 sites in Thailand
- Volunteers
- 80 people
- Sponsor
- Mahidol University
the Optimum Brushing Force for Dental Plaque Removal and the Effect of Brushing Force on Enamel Characteristic
Evaluation of the Optimum Brushing Force on Dental Plaque Removal and the Abrasive Effect of Brushing Force on Enamel Surface.
Objective 1. To determine the optimum brushing force for dental plaque removal. 2. To investigate the effect of brushing force on enamel characteristic.
- Trial name
- NCT04675736
- Testing
- brushing force
- Where
- Thailand
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Stroke, Ischemic
The Effect of The Five-Session Dual-tDCS On Lower-Limb Performance in Sub-Acute Stroke
The aim of the present study is to determine the effect of the five-session dual-tDCS combine with physical therapy on gait performance, balance and lower limbs muscle strength in patients with subacute stroke.
- Trial name
- NCT04287231
- Testing
- Transcranial direct current stimulation
- Where
- Thailand
- Volunteers
- 24 people
- Sponsor
- Mahidol University
Coagulopathy, Cardiac Surgery, Cardiopulmonary Bypass
Coagulopathy in Cardiac Surgery
Coagulopathy in cardiac surgery; a quaternary-care academic center experience Objectives: Primary: To determine incidence of coagulopathy after cardiac surgery in Thai people To determine incidence of resternotomy for stop…
- Trial name
- NCT03475940
- Where
- 2 sites in Thailand
- Volunteers
- 398 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Melasma
Efficacy and Safety of Using Combination of 755-nm Picosecond Alexandrite Laser and 2% Hydroquinone Compared With 2% Hydroquinone Alone for the Treatment of Melasma: a Randomized Split-face Controlled Trial
This study aims to assess the efficacy and safety of using combination of 755-nm picosecond alexandrite laser and 2% hydroquinone compared with 2% hydroquinone alone for the treatment of melasma: A randomized split-face…
- Trial name
- NCT04597203
- Testing
- 755-nm picosecond alexandrite laser with topical 2% hydroquinone, topical 2% hydroquinone
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Shoulder Impingement Syndrome, Subacromial Impingement
The Effect of Mobilization With Movement in Individuals With Shoulder Impingement Syndrome
This study conducted to see the effect of adding mobilization with movement to conventional physical therapy to the subject with shoulder impingement syndrome.
- Conditions
- Shoulder Impingement Syndrome, Subacromial Impingement, Subacromial Impingement Syndrome, Subacromial Pain Syndrome
- Trial name
- SIS (NCT04599127)
- Testing
- Mobilization with movement, Conventional physical therapy
- Where
- Indonesia
- Volunteers
- 22 people
- Sponsor
- Mahidol University
Keloid
The Safety and Efficacy of Thermo-mechanical System for Fractional Ablation Associated Triamcinolone Acetonide Drug Delivery for the Treatment of Hypertrophic Scars and Keloids
This study aims to assess the safety and efficacy of Thermo-mechanical system for fractional ablation associated triamcinolone acetonide drug delivery for the treatment of Hypertrophic scars and Keloids.
- Trial name
- NCT04597060
- Testing
- Thermomechanical system with corticosteroids, corticosteroid injection
- Where
- Thailand
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Cholangiocarcinoma, Biliary Stricture
DNA Methylation Biomarker for Diagnosis of Cholangiocarcinoma in Patients With Bile Duct Stricture
DNA methylation biomarker for diagnosis of cholangiocarcinoma in patients with bile duct stricture has high sensitivity and specificity compared with cytology from the brush specimens
- Conditions
- Cholangiocarcinoma, Biliary Stricture, DNA Methylation, Brush Cytology
- Trial name
- DNA (NCT04568512)
- Testing
- Control, Cholangiocarcinoma
- Where
- Thailand
- Volunteers
- 67 people
- Sponsor
- Mahidol University
Bilateral Total Knee Arthroplasty
Efficacy of Pain Control in Different Bupivacaine Dose in Periarticular Injection in Bilateral Total Knee Arthroplasty
To study efficacy of postoperative pain control of different concentrations of bupivacaine for periarticular infiltration, part of multimodal analgesia, in bilateral total knee arthroplasty.
- Trial name
- NCT03249662
- Testing
- bupivacaine 200 mg, bupivacaine 100 mg
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Focus on Laser Treatment of Nevus of Ota in Thai Patients
A Retrospective Study on Laser Treatment of Nevus of Ota in Thai Patients
A retrospective study on efficacy and complication of laser treatment (Q-switched Nd:YAG and picosecond laser) of nevus of Ota in Thai patients
- Trial name
- NCT04481178
- Testing
- Laser (QS, Picosecond laser)
- Where
- Thailand
- Volunteers
- 79 people
- Sponsor
- Mahidol University
Cervical Spine Degeneration
Analgesic Effectiveness of Nefopam in Patients Undergoing Anterior Cervical Spine Surgery
Nefopam is a benzoxazocine derivative which is non-opioid and non NSAIDs. The previous studies showed that nefopam can inhibit reuptake of serotonin, norepinephrine and dopamine.
- Trial name
- NCT03955705
- Testing
- Nefopam 20 mg/ml, Normal saline
- Where
- Thailand
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Renal Insufficiency, Infection
Low-dose VS High-dose IV Cyclophosphamide for Proliferative LN in Children
Proliferative lupus nephritis (LN)is the predominant cause of morbidity and mortality in juvenile Systemic Lupus Erythematosus (SLE).
- Trial name
- Low/highIVCY (NCT01861561)
- Testing
- Low-dose intravenous cyclophosphamide, High-dose intravenous cyclophosphamide
- Where
- Thailand
- Volunteers
- 43 people
- Sponsor
- Mahidol University
Acne Vulgaris, Acne
Moisturizer Containing Licochalcone A, Decanediol, L-carnitine and Salicylic Acid in Reducing Relapsing of Acne
Moisturizer containing the active ingredients of licochalcone A, decanediol, L-carnitine, and salicylic acid may be beneficial in alternative treatment of acne in maintenance phase.
- Trial name
- NCT04002024
- Testing
- Moisturizer with active ingredients
- Where
- Thailand
- Volunteers
- 50 people
- Sponsor
- Mahidol University
Hepatic Encephalopathy
Efficacy of Combined Oral L-ornithine-L-aspartate and Lactulose in Patients With Hepatic Encephalopathy
Hypothesis: Is the combination of oral L-ornithine-L-aspartate and lactulose more efficacious than oral lactulose alone in treatment of hepatic encephalopathy? Study design; Randomized, double-blinded, placebo controlled trial
- Trial name
- NCT00740142
- Testing
- L-ornithine-L-aspartate and lactulose
- Where
- Thailand
- Volunteers
- 35 people
- Sponsor
- Mahidol University
Ascending Aortic Atheromatous Plaque
Risk Factors of Ascending Aortic Atheromatous
Background Incidence of perioperative stroke In cardiac surgery is 2.6-5.2%. Ascending aortic atheromatous plaque and stroke are strongly associated.
- Trial name
- NCT03381222
- Testing
- epiaoryic scan
- Where
- Thailand
- Volunteers
- 239 people
- Sponsor
- Mahidol University