Clinical trials: sponsored by Mahidol University
Spine Disease
GDFT Based on PPV Compared With Standard Fluid Therapy in Patients Undergoing Complex Spine Surgery: RCT
The investigators will do the Goal directed fluid therapy by protocolized fluid management in the experimental group, using PPV to guide the fluid administration, compare with standard fluid management in patients undergoing…
- Trial name
- NCT03164811
- Testing
- goal directed fluid therapy, Controlled
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Contraception, Intrauterine Device
10% Lidocaine Spray for Intrauterine Device Insertion
Intrauterine device (IUD) insertion is a procedure that can cause pain. Fear of pain during IUD insertion is a barrier to use of this method.
- Trial name
- LidocaineIUD (NCT03870711)
- Testing
- lidocaine spray
- Where
- Thailand
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Clinical Outcome, Endodontic Disease
Clinical Outcomes of Bio-MA and ProRoot MTA in Endodontic Treatment
The purpose of this study is to compare the endodontic outcomes of Bio-MA and ProRoot MTA in pulpotomy, orthograde MTA apical barrier, root perforation repair, endodontic microsurgery.
- Trial name
- NCT04243993
- Testing
- Calcium silicate cement
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Carotid Stenosis, Carotid Endarterectomy
Major Adverse Cardiac Events After Carotid Endarterectomy
Carotid endarterectomy is the operation for curing the significant carotid artery stenotic patients who are also at high cardiac risk. This retrospective study is to find out the incidence and risk factors related.
- Conditions
- Carotid Stenosis, Carotid Endarterectomy, Adverse Cardiac Events
- Trial name
- NCT03596229
- Where
- Thailand
- Volunteers
- 175 people
- Sponsor
- Mahidol University
Stroke
Effects of Dual-transcranial Direct Current Stimulation During Physical Therapy in Sub-acute Stroke
The aim of the present study is to evaluate the possible effect of using dual-tDCS applied during conventional physical therapy on lower limb function in stroke patients.
- Trial name
- NCT04051671
- Testing
- Transcranial direct current stimulation
- Where
- Thailand
- Volunteers
- 19 people
- Sponsor
- Mahidol University
Epilepsy
Generic Substitution of Original Levetiracetam in Thai Epilepsy Patients
The retrospective pre-post observational study was conducted to evaluate the real-world evidence of efficacy and tolerability of generic levetiracetam (oral tablet) which was switched from original levetiracetam (oral tablet) in…
- Trial name
- NCT04132063
- Testing
- Generic levetiracetam
- Where
- Thailand
- Volunteers
- 75 people
- Sponsor
- Mahidol University
Immunology, Nephrology
Immune Response to Influenza Vaccine in ESRD Patients
On-line hemodiafiltration (HDF) clears more azotaemic toxins compared to high-flux hemodialysis (HD). The response to vaccination is impaired in dialysis patients.
- Trial name
- NCT04122222
- Testing
- Influenza vaccine
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Pertussis
2-year Follow-up After a Single Dose Acellular Pertussis Vaccination
In July 2015-November 2016, a phase II/III randomized, observer-blind,controlled study of two acellular Pertussis vaccines (aP standalone and TdaP combined vaccined) manufactured by BioNet-Asia Co., Ltd.
- Trial name
- NCT04113655
- Testing
- Pertagen (aP BioNet), Boostagen (TdaP BioNet), Adacel
- Where
- 2 sites in Thailand
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Pertussis
3-year Follow-up After a Single Dose Acellular Pertussis Vaccination
In July 2015-November 2016, a phase II/III randomized, observer-blind,controlled study of two acellular Pertussis vaccines (aP standalone and TdaP combined vaccined) manufactured by BioNet-Asia Co., Ltd.
- Trial name
- NCT04102137
- Testing
- Pertagen (aP BioNet), Boostagen (TDaP BioNet), Adacel
- Where
- Thailand
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Papanicolaou Smear
Assessing the Psychosocial Burden in Women With an Abnormal Pap Results After Screening Interventions
The primary purpose of this study is to assess the psychosocial burden in women who have experienced an abnormal pap results after screening interventions.
- Trial name
- NCT00520117
- Where
- Thailand
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Caesarean Section, Spinal Anesthesia
Effect of Bilateral Quadratus Lumborum Block for Pain Relief in Patients With Cesarean Section
Cesarean section commonly induces moderate to severe pain for 48 hours. These patients have additional compelling reasons to provide adequate pain relief as early mobilization is a key factor to prevent the risk of thromboembolic…
- Conditions
- Caesarean Section, Spinal Anesthesia, Quadratus Lumborum Block, Analgesia
- Trial name
- NCT03199170
- Testing
- Intrathecal morphine, Bilateral Quadratus Lumborum Block, Intrathecal morphine with bilateral Quadratus Lumborum Block
- Where
- Thailand
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Positive-Pressure Respiration/Methods, Esophagus/Physiopathology
Intraoperative PEEP Setting During Laparoscopic Gynecologic Surgery
The creation of pneumoperitoneum during laparoscopic surgery can have significant effects on the respiratory system including decreased respiratory system compliance, decreased vital capacity and functional residual capacity and…
- Conditions
- Positive-Pressure Respiration/Methods, Esophagus/Physiopathology, Pleura/Physiopathology, Gynecologic Surgical Procedures
- Trial name
- NCT03256396
- Testing
- PEEP setting based on esophageal pressure measured
- Where
- Thailand
- Volunteers
- 44 people
- Sponsor
- Mahidol University
Acute Kidney Injury
Preloading Magnesium Attenuate Cisplatin-induced Nephrotoxicity
The purpose of this study is to determine whether magnesium preloading reduce incident of cisplatin induced acute kidney injury in head and neck cancer who receiving low dose cisplatin (40 mg/m2 weekly for 7 weeks).
- Trial name
- PRAGMATIC (NCT02481518)
- Testing
- Magnesium, Control
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Mahidol University
Pulmonary Disease, Chronic Obstructive
Modified Dantien Salee Yoga Training Program in Chronic Obstructive Pulmonary Disease Rehabilitation
COPD patients will be recruited and assigned into one of each group: 1) Control group or 2) Yoga group. In Yoga groups, subjected will be asked to participate in Modified Dantien Yoga training for 12 weeks (3 times/week, 60…
- Trial name
- NCT02770677
- Testing
- Modified Dantien Salee Yoga Training Program
- Where
- Thailand
- Volunteers
- 12 people
- Sponsor
- Mahidol University
Intubation Skill, Laryngeal Mask Airway Insertion Skill
Evaluation of Learning Curve of Manual Skills in Anesthesia Residents
To determine number of cases need to perform in new anesthesia residents to be proficient in manual skills.
- Conditions
- Intubation Skill, Laryngeal Mask Airway Insertion Skill, Spinal Anesthesia Skill, Epidural Anesthesia Skill
- Trial name
- NCT01236183
- Where
- Thailand
- Volunteers
- 24 people
- Sponsor
- Mahidol University
Food Allergy
Efficacy of Lyophilized Food Extracts for Skin Prick Tests and Atopy Patch Test at Different Storage Time
Comparison the result of skin prick tests and atopy patch test of lyophilized food extracts at different storage time (0, 3 and 6 months) after preparation
- Trial name
- NCT03645629
- Testing
- skin test with food at different storage times
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Allergic Rhinitis Due to Animal Hair and Dander
Comparison Between Local and Imported Skin Prick Testing Result of Rat and Mouse Allergen Extracts
In respiratory allergy patients, skin prick test results of local rat and mouse allergen extracts are not significant different from imported ones
- Trial name
- NCT03645161
- Testing
- rat and mouse skin test
- Where
- Thailand
- Volunteers
- 230 people
- Sponsor
- Mahidol University
Allergy to Arthropod Sting
Comparison of Skin Prick Testing and Intradermal Skin Test Result of Local and Imported Insect Allergen Extracts
Comparison the results of skin prick testing and Intradermal skin test result of local and imported insect allergen extracts in patients with serious insect sting allergy reactions
- Trial name
- NCT03645291
- Testing
- Local insect allergen extracts skin test
- Where
- Thailand
- Volunteers
- 27 people
- Sponsor
- Mahidol University
Stroke
Sensorimotor Integration Exercises on Post-stroke Balance and Fall Efficacy
To study the effect of sensorimotor integration exercises on balance and fall efficacy in sub-acute stroke by performing 18 balance training exercises with three progressive steps.
- Trial name
- SMIE (NCT03584035)
- Testing
- sensory motor integration exercises, conventional physiotherapy
- Where
- 2 sites in Burma
- Volunteers
- 46 people
- Sponsor
- Mahidol University
Adult ICU Patients, Pain, Acute
Incidence of Inadequate Pain Treatment in Ventilated Critically Ill Surgical Patients
In SICU, Siriraj hospital there were no protocols place for the management of pain. All decisions were made according the attending physicians.
- Trial name
- NCT03641911
- Where
- Thailand
- Volunteers
- 118 people
- Sponsor
- Mahidol University