Clinical trials: sponsored by Mahidol University
Osteoporotic Fractures, Femoral Neck Fracture
Short-term Functional Recovery Between Early- and Late Bisphosphonate Treatment Following Hemiarthroplasty
Femoral neck fracture in the elderly is one indication for initiating osteoporosis treatment. Bisphosphonates remain the first line therapy; however, many orthopaedic surgeons concern regarding their effects on fracture healing…
- Trial name
- NCT02148848
- Testing
- Risedronate
- Where
- Thailand
- Volunteers
- 86 people
- Sponsor
- Mahidol University
Allergy to Grass Pollen, Allergic Rhinitis Due to Weed Pollens
Grass Sensitisation and Allergic Rhinitis in Thai Patients
Allergic rhinitis patients are the patients who have nasal symptoms when triggered by indoor or outdoor allergens. Outdoor allergen can be divided into grass, tree, or weed.
- Trial name
- NCT01686022
- Testing
- Immunoblot
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Fibrosis, Liver
Diffusion-weighted Imaging Magnetic Resonance for Assessing Liver Fibrosis
Several noninvasive radiological techniques have been investigated for the diagnosis of liver fibrosis and cirrhosis among patients with chronic infection with hepatitis B virus or hepatitis C virus.
- Trial name
- NCT02682108
- Testing
- Diffusion-weighted magnetic resonance imaging (DW-MRI)
- Where
- Thailand
- Volunteers
- 121 people
- Sponsor
- Mahidol University
Brain Tumor
The Use of Fentanyl in General Anesthesia for Craniotomy With or Without 0.5% Levobupivacaine Scalp Block
This study evaluates the use of fentanyl during craniotomy in two groups of brain tumor patients. The control group will receive standard general anesthesia with the use of fentanyl for intraoperative pain control and the study…
- Trial name
- NCT02558569
- Testing
- Levobupivacaine, NSS
- Where
- 2 sites in Thailand
- Volunteers
- 128 people
- Sponsor
- Mahidol University
Non-alcoholic Fatty Liver Disease
The Effects of Type of Exercise in Non-alcoholic Fatty Liver Disease
The type of physical activity such as, aerobic or resistant exercise required to reduce liver fat content in patient with non-alcoholic fatty liver disease (NAFLD) remains unclear.
- Trial name
- NCT02679417
- Testing
- exercise
- Where
- Thailand
- Volunteers
- 38 people
- Sponsor
- Mahidol University
Bone Density
Vitamin D and Calcium Supplement Attenuate Bone Loss Among HIV- Infected Patients Receiving Tenofovir Disoproxil Fumarate, Lamivudine or Emtricitabine and Efavirenz
The purpose of this study is to determine whether calcium and vitamin D supplement can attenuate bone loss in HIV-infected-patients in Thailand who receive Tenofovir disoproxil fumarate.
- Trial name
- NCT02827643
- Testing
- TDF/3TC or FTC/EFV plus Calcium and vitamin D supplement, TDF/3TC or FTC/EFV
- Where
- Thailand
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Cervical Spondylosis
Recovery Profiles After c Spine Surgery: With or Without Dexmedetomidine as an Anesthetic Adjuvant
The purpose of this study is to determine the recovery profiles after general anesthesia in patient undergoing anterior cervical spine surgery.
- Trial name
- NCT02819089
- Testing
- Dexmedetomidine, NSS
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Mahidol University
Pain, Postoperative
Pain Prevalence After Cesarean Section in Siriraj Hospital
Spinal morphine has been widely provided for acute postoperative analgesia. However, the analgesic effect of spinal morphine usually last 12-24 hours.
- Trial name
- NCT02810639
- Where
- Thailand
- Volunteers
- 297 people
- Sponsor
- Mahidol University
Onychomycosis, Chronic Paronychia
A Pilot Study - Safety and Efficacy of Nailprotex® for Onychomycosis Treatment
This study was designed to demonstrate the efficacy of this product in non-dermatophyte (Scytalidium dimidiatum) onychomycosis and chronic paronychia treatment in Thai patients.
- Trial name
- NCT02464826
- Testing
- Nailprotex
- Where
- Thailand
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Keloids, Hypertrophic Scars
Effect of Pulse Width on Scar Treatment Using a 595-nm Pulsed Dye Laser
To investigate the effect of pulse width on the treatment response of keloidal and hypertrophic sternotomy scars to a 595-nm pulsed dye laser
- Trial name
- NCT00142441
- Testing
- Pulsed dye laser
- Where
- Thailand
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Obstructive Sleep Apnea
Randomized Cross-over TRD and CPAP for OSA
The objectives of this study is to compare short-term outcomes of CPAP and TRD in the treatment of obstructive sleep apnea. Study design is a randomized cross-over trial during 3-weeks period of each treatment in 36 patients.
- Trial name
- NCT02788487
- Testing
- Tongue retaining device, CPAP
- Where
- Thailand
- Volunteers
- 36 people
- Sponsor
- Mahidol University
Lentigines, Post Inflammatory Hyperpigmentation
Topical Corticosteroids on the Incidence of Postinflammatory Hyperpigmentation After QsNdYAG Laser
To investigate the benefit of the application of topical high potency steroid on the incidence of post inflammatory hyperpigmentation after laser treatment.
- Trial name
- NCT02492373
- Testing
- topical 0.05% Clobetasol propionate ointment, Q switched Nd:YAG laser 532 nm
- Where
- Thailand
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Enlarged Pores
Er:YAG Laser for Treatment of Enlarged Pores
To investigate the efficacy of Erbium:Yttrium aluminum garnet laser (Er:YAG) in the treatment of enlarged pores.
- Trial name
- NCT02544958
- Testing
- Er:YAG laser
- Where
- Thailand
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Hypotension and Shock
A Comparison of Crystalloid Alone Versus Crystalloid Plus Colloid in Shock Resuscitation
Fluid resuscitation is the most effective treatment of shock. Isotonic crystalloid solution is the current recommended initial fluid resuscitation.
- Trial name
- NCT02782819
- Testing
- Isotonic crystalloid solution resuscitation, Colloid solution resuscitation
- Where
- Thailand
- Volunteers
- 320 people
- Sponsor
- Mahidol University
Immediate Type Hypersensitivity
Comparison of Skin Prick Testing Results of Local and Imported Pollen Allergen Extracts and Specific IgE
Pollen allergen extracts are prepared locally and checked for efficacy by comparison to imported allergens and specific IgE.
- Trial name
- NCT02764827
- Testing
- Pollen sensitization
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Quality of Life, Sleep Apnea Syndromes
Compare Outcomes of SMG and CPAP in OSA
The objectives of this study is to compare short-term outcomes of CPAP and Adjustable thermoplastic oral appliance in the treatment of obstructive sleep apnea.
- Trial name
- NCT02766179
- Testing
- CPAP, Somnoguard
- Where
- Thailand
- Volunteers
- 50 people
- Sponsor
- Mahidol University
Insect Sting Allergy
The Causative Insects in Severe Insect Sting Allergy
Study the causative insect by skin prick test and sIgE to wasp, bee and fire ants are important but false positive by crossreactivity can occur.
- Trial name
- NCT02764242
- Testing
- Skin prick test, sIgE measurement
- Volunteers
- 20 people
- Sponsor
- Mahidol University
Immediate Hypersensitivity
Comparison Between spIgE and Skin Prick Test of Local and Imported Aeroallergens
The prevalence of Allergic rhinitis(AR) and asthma was increased world wide. In 1998, ISAAC found that prevalence of AR and asthma inThailand was in moderately high group.
- Trial name
- NCT02561390
- Testing
- Skin prick test, specific IgE measurement
- Where
- Thailand
- Volunteers
- 84 people
- Sponsor
- Mahidol University
Immediate Hypersensitivity
Comparison of Difference Histamine Concentration (1, 5 and 10 mg/ml) for Skin Prick Test Positive Control
Skin prick test (SPT) was used for diagnostic test for type 1 hypersensitivity. The efficacy and safety of SPT were proved. The positive control of SPT is histamine.
- Trial name
- NCT02561429
- Testing
- SPT
- Where
- Thailand
- Volunteers
- 180 people
- Sponsor
- Mahidol University
Normal Non-fluency
Measurements of Exhaled Nitric Oxide in Healthy Subjects in Thailand
The purpose of this study is to determine fractional exhaled nitric oxide (FeNO) level in healthy subjects among Thai populations.
- Trial name
- FeNO_nor (NCT02554617)
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mahidol University