Clinical trials: sponsored by Mahidol University
Bronchial Asthma
Association Between Fractional Exhaled Nitric Oxide and Asthma Control
The purpose of this study is to determine mean or median of fractional exhaled nitric oxide (FeNO) in Thai atopic asthmatic patients that divided into subgroups due to level of asthma control according to the global initiative…
- Trial name
- FeNO_AS (NCT01197690)
- Where
- Thailand
- Volunteers
- 62 people
- Sponsor
- Mahidol University
Chronic Sinusitis
Efficacy and Complication of Gentamicin Nasal Irrigation in Chronic Rhinosinusitis
The propose of this study to determine efficacy and complication of gentamicin nasal irrigation in chronic rhinosinusitis
- Trial name
- NCT01430026
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Food Allergy
Atopy Patch Test in Children With Food Allergy-related Gastrointestinal Symptoms
Positive reactions in Atopy patch test in children with food allergy-related gastrointestinal symptoms
- Trial name
- APT (NCT01164293)
- Testing
- Atopy patch test with food allergen
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Acquired Hallux Valgus
Prevalence and Clinical Characteristics of the Fungal Nail and Feet Infection in Patients With Hallux Valgus
This study was designed to demonstrate the prevalence of onychomycosis in hallux valgus patients. Additionally, all the prevalence of tinea pedis, the pattern of clinical manifestations, risk factors and coexistence foot…
- Trial name
- NCT02464839
- Where
- Thailand
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Infection Due to Escherichia Coli, Acute Pyelonephritis
Sitafloxacin and Ertapenem Treatment for Acute Pyelonephritis Caused by Escherichia Coli
The aim of the investigators' study was to evaluate oral and non carbapenem antimicrobial agents which can be used in outpatient for the treatment of non-bacteremic acute pyelonephritis caused by Extended Spectrum Beta Lactamase…
- Trial name
- SETAP (NCT02537847)
- Testing
- Sitafloxacin, Ertapenem
- Where
- Thailand
- Volunteers
- 96 people
- Sponsor
- Mahidol University
Hospital Infection
Efficacy of Polymyxin B Against Infections Caused by Extensively Drug-resistant (XDR) Gram-Negative Bacteria
The objective of the study is to evaluate the efficacy of Polymyxin B for treatment Gram negative bacterial infection. The hypothesis of study is Polymyxin B would be the new antibacterial agents for Thai Gram negative infected…
- Trial name
- XDR (NCT02328183)
- Testing
- Polymyxin B
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Mahidol University
Cytochrome P-450 CYP2B6, Efavirenz
Influence of Cytochrome P2B6 on Efavirenz Dose in HIV-infected Thai Patients
Genetic polymorphisms of cytochrome P450 2B6 (CYP2B6) are associated with lower rate of EFV metabolism and lead to high exposure, as well as a higher risk of neuropsychiatric adverse event especially homozygous variant CYP2B6…
- Conditions
- Cytochrome P-450 CYP2B6, Efavirenz, HIV
- Trial name
- NCT02421289
- Testing
- Efavirenz, CYP450 2B6
- Where
- Thailand
- Volunteers
- 190 people
- Sponsor
- Mahidol University
Gastrointestinal Bleeding
Efficacy of Wireless Capsule Endoscopy and CT Enterography in Obscure Gastrointestinal Bleeding
The purpose of this study is to compare the efficacy between video capsule endoscopy and CT enterography in diagnosis of obscure gastrointestinal bleeding.
- Trial name
- NCT02219568
- Testing
- CT enterography, video capsule endoscopy
- Where
- Thailand
- Volunteers
- 52 people
- Sponsor
- Mahidol University
Hypertrophic Scars
Treatment of Hypertrophic Scars Using Fractional Laser and Fractional Laser-assisted Topical Corticosteroid Delivery
The objective of this study is to evaluate the efficacy and safety of using ablative fractional laser- assisted topical corticosteroid delivery for the treatment of hypertrophic scar.
- Trial name
- NCT02487212
- Testing
- 0.05% Clobetasol propionate, Petrolatum gel, Fractional Erbium:Yag (2,940-nm) laser
- Where
- Thailand
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Ceramic and Dental Enamel Wear
Clinical Performance and Wear Mechanism of Hot-Pressed Ceramic Crowns
The objectives of this study are to characterize the clinical performance and wear mechanisms of all-ceramic posterior crowns. The wear rate of all-ceramic crowns and opposing enamel in selected patients will be quantified.
- Trial name
- NCT00889239
- Testing
- lithia-disilicate-based crown
- Where
- Thailand
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Dental Restoration Wear
Properties and Clinical Performance of Zirconia-based Dental Ceramics
The objectives of this study are to determine the clinical performance of zirconia-based dental prostheses and their related properties.
- Trial name
- NCT00737308
- Testing
- ceramic crown
- Where
- 2 sites in Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Septic Shock, Severe Sepsis
Efficacy of Hydrocortisone in Treatment of Severe Sepsis/Septic Shock Patients With Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
Severe sepsis/septic shock is a serious condition associated with high mortality rate. Hydrocortisone has been recommended as a useful treatment to decrease mortality in hemodynamically unstable septic shock patients, not…
- Conditions
- Septic Shock, Severe Sepsis, Acute Lung Injury, Acute Respiratory Distress Syndrome
- Trial name
- NCT01284452
- Testing
- Hydrocortisone
- Where
- Thailand
- Volunteers
- 197 people
- Sponsor
- Mahidol University
Falciparum Malaria
Safety and Efficacy Study of Adjunctive Rosiglitazone in the Treatment of Uncomplicated Falciparum Malaria
The purpose of this study is to examine the safety, tolerability, and efficacy of adjunctive rosiglitazone in the treatment of uncomplicated P.falciparum malaria.
- Trial name
- NCT00149383
- Testing
- Rosiglitazone
- Where
- Thailand
- Volunteers
- 140 people
- Sponsor
- Mahidol University
Patient Fall, Muscle Balance
Home Based Exercise in Preventing Fall and Improving Balance in Older People
Prior studies have shown multifaceted falls prevention program with home-based exercise reduced falls significantly in the community setting.
- Conditions
- Patient Fall, Muscle Balance, Fear of Falling, Quality of Life
- Trial name
- NCT02089815
- Testing
- Home based exercise, fall prevention education and counseling
- Where
- Thailand
- Volunteers
- 439 people
- Sponsor
- Mahidol University
Dyspepsia, Helicobacter-associated Gastritis
High Dose PPI Triple Therapy Versus Sequential Therapy for Helicobacter Pylori Eradication
The purpose of this study is to compare the efficacy between 1-day high dose PPI-based triple therapy vs. 10-day sequential therapy for Helicobacter pylori eradication in functional dyspepsia patients.
- Conditions
- Dyspepsia, Helicobacter-associated Gastritis, Stomach Disorders
- Trial name
- NCT01888237
- Testing
- Double dose of PPI, sequence of drug use
- Where
- Thailand
- Volunteers
- 118 people
- Sponsor
- Mahidol University
Wheat Allergy, Child
The Natural History of Wheat Hypersensitivity in Thai Children
Wheat allergy is affected 0.4-1% and is a major staple of the worldwide diet. Wheat avoidance is exceedingly difficult and imposes major dietary restriction.
- Trial name
- NCT01801748
- Testing
- oral wheat challenge
- Where
- Thailand
- Volunteers
- 43 people
- Sponsor
- Mahidol University
Avian Influenza
Evaluation of Priming Effects by PLAI Vaccine on the Subsequent Response to Inactivated H5N1 Vaccine
This study aim to compare immunogenicity of the inactivated H5 influenza vaccine single dose between subjects previously vaccinated with LAIV H5N2 and naïve subjects
- Trial name
- NCT02229357
- Testing
- OrniFlu® inactivated vaccine
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Analgesia After ACL Reconstruction
Femoral Nerve Block for Analgesia After Anterior Cruciate Ligament Reconstruction
Femoral nerve block using 0.25% bupivacaine or 0.5% bupivacaine provides a longer time for analgesia after Anterior Cruciate Ligament (ACL) reconstruction.
- Trial name
- FNB for ACLR (NCT01593566)
- Testing
- 0.25% Bupivacaine, 0.5% Bupivacaine
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Mahidol University
Endometriosis
Postoperative Desogestrel for Endometriosis Related Pain
Endometriosis is one of the most common disease in reproductive aged women.Surgical intervention has a significant symptoms relief. However, symptom recurrence is often after surgery.
- Trial name
- NCT01559480
- Testing
- Desogestrel
- Where
- 2 sites in Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Body Weight Changes
Comparison of Body Weight Change During Contraception With Belara and Yasmin
The purpose of this study is to evaluate different side effect in contraceptive use of two oral combined contraceptive pills (OCP)in combination of 30 mcg ethinylestradiol/2 mg chlormadinone acetate (Belara®) and 30 mcg…
- Trial name
- NCT01608698
- Testing
- 30 mcg ethinylestradiol/2 mg chlormadinone acetate, 30 mcg ethinylestradiol/3 mg drospirenone
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mahidol University