Clinical trials: sponsored by Mahidol University
Hypertension, Craniotomy
Control of Emergence Blood Pressure During Craniotomy for Tumor Surgery Between Labetolol and Diltiazem
The purpose of this study is to determine the effectiveness of the antihypertensive drugs in the control of emergence blood pressure after tumor resection craniotomy; compared between labetalol (Avexa) and diltiazem (Herbessor).
- Trial name
- NCT01408524
- Testing
- Diltiazem, Labetalol
- Volunteers
- 184 people
- Sponsor
- Mahidol University
Solar Elastosis
Histologic Response to UVA and UVB Exposure During the Use of Sunscreen
Anti-inflammatory and anti-oxidant agents have become the important ingredients in sunscreen. However, there is no histologic study about the effects of anti-inflammatory and anti-oxidative properties of sunscreen to prevent…
- Trial name
- NCT01892150
- Testing
- Sunscreen
- Where
- Thailand
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Cryptococcal Meningitis, HIV/AIDS
Clinical Outcomes of Cryptococcal Meningitis Among HIV-infected Patients in the Era of Antiretroviral Therapy
Cryptococcal meningitis is one of the most common central nervous system infections among HIV-infected patients. The outcome is generally severe.
- Trial name
- NCT02098525
- Where
- Thailand
- Volunteers
- 195 people
- Sponsor
- Mahidol University
Foot Deformity Congenital
Effectiveness of Parent's Manipulation in Newborn With Metatarsus Adducts. a Randomized Controlled Trial
The purpose of this study is to determine whether the result of parent's feet manipulation compared with nonmanipulated group within first 6 months of life and observe spectrum of the disease within this period.
- Trial name
- NCT02093507
- Testing
- parents manipulation
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Mahidol University
Anesthesia, Hypotension
Anesthetic Advantages of Dexmedetomidine for Hypotensive Anesthesia
The aim of this study was to evaluate the positive anesthetic properties such as reduce intraoperative analgesic requirement, time to extubation and recovery, and early postoperative pain of dexmedetomidine used as a hypotensive…
- Trial name
- NCT02083055
- Testing
- Dexmedetomidine, Nitroglycerin
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Infection After Transfusion
The Immunomodulation Effect of Blood Transfusion in Operative Spine Surgery Patients
The purpose of this study is to investigate the effect of transfusion of allogeneic (homologous) red cells on the immunologic parameters such as T-cells as well as natural killer cell count/function, various interleukins, TNF…
- Trial name
- NCT02069210
- Testing
- Blood transfusion
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Morphine
Epidural Low Dose Morphine in Postoperative Pain After Posterior Lumbar Spinal Surgery
The effect of epidural low-dose morphine-soaked microfibrillar collagen sponge in postoperative pain control after posterior lumbar spinal surgery: a randomized, double-blind, placebo-controlled study
- Trial name
- NCT02067338
- Testing
- 1 mg morphine soak in epidural oxidized cellulose, normal saline
- Where
- Thailand
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Varicose Veins, Venous Insufficiency
The Party Balloon Assisted Valsalva in Diagnosis of Superficial Venous Valvular Reflux of Lower Limb
This study was designed to compare the party balloon assisted Valsalva with the conventional Valsava for exhibiting the reverse venous flow in superficial venous valvular incompetence duplex examination.
- Trial name
- NCT02051439
- Testing
- Valsava
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Keloids, Hypertrophic Scars
Effect of Transparent, Self-drying Silicone Gel on the Treatment of Hypertrophic Abdominal Scars
Keloids and hypertrophic scars are a common subject of dermatologic consultations. Therapeutic management of such conditions remains challenging because of their high rate of recurrence and lack of curative treatment.
- Trial name
- NCT01078428
- Testing
- Topical silicone gel, Vaseline
- Where
- Thailand
- Volunteers
- 38 people
- Sponsor
- Mahidol University
Acne Scar, Wrinkle
Fractional CO2 Treatment of Acne Scars in Asians
The objective of this study is to investigate the efficacy and side effects of a fractional CO2 laser for treatment of acne scar in Asians.
- Trial name
- CO2 (NCT00748462)
- Testing
- Fractional CO2 Laser
- Where
- Thailand
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Bleeding
Reduction Bleeding in Laminectomy With Double Doses of Tranexamic Acid
Tranexamic acid has benn widely used to reduce perioperative bleeding in several operations such as cardiac surgery, liver transplant and joint arthroplasty with good results.
- Trial name
- NCT01643135
- Testing
- tranexamic acid, 0.9% NaCl
- Where
- Thailand
- Volunteers
- 78 people
- Sponsor
- Mahidol University
Primary Osteoarthritis of Knee Nos
Efficacy of Low-dose Intra-articular Tranexamic Acid in Total Knee Replacement
The purpose of this study is to determine 1) the effective dosage of intra-articular tranexamic acid injection for controlling blood loss and blood transfusion requirement in conventional total knee replacement, and 2) whether…
- Trial name
- NCT01850394
- Testing
- Tranexamic Acid, Physiologic saline
- Where
- Thailand
- Volunteers
- 152 people
- Sponsor
- Mahidol University
Observation of Neuromuscular Block, Disease (or Disorder); Gynecological
Clinical Characteristics of Spinal Levobupivacaine: Hyperbaric Compared With Isobaric Solution
The authors would like to investigate the blocking characteristics, surgical quality and side effects of intrathecal levobupivacaine whether there are any differences between the hyperbaric and the isobaric formulation for…
- Trial name
- NCT01349751
- Testing
- isobaric levobupivacaine, hyperbaric levobupivacaine
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Mahidol University
Ocular Surface Disease
Ocular Surface Reconstruction With Cultivated Autologus Mucosal Epithelial Transplantation
The purpose of this study is to elucidate the appropriate condition of developing cultivated autologous oral mucosal epithelial graft and evaluate the surgical outcome of transplantation of the cultivated cells in the patients.
- Trial name
- NCT01942421
- Testing
- Cultivated mucosal epithelial transplantation
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Mahidol University
Asthma
The Additive Anti-inflammatory Effect of Simvastatin in Combination With Inhaled Corticosteroids in Asthma
We hypothesize that simvastatin in combination with ICS might have synergistic anti-inflammatory effects on airway inflammation in asthmatic patients
- Trial name
- NCT00792337
- Testing
- simvastatin, B1-6-12
- Where
- Thailand
- Volunteers
- 53 people
- Sponsor
- Mahidol University
Asthma
Comparison of Anti-inflammatory Effects of Seroflo and Seretide in Patients With Asthma
The purpose of this study is to test hypothesis if Sereflo (ICS/LABA) could reduce airway inflammation in asthmatic patients in the same as Seretide.
- Trial name
- NCT01274325
- Testing
- Sereflo, Seretide
- Where
- 2 sites in Thailand
- Volunteers
- 51 people
- Sponsor
- Mahidol University
Chronic Obstructive Pulmonary Disease
Innate Immune Responses in Chronic Obstructive Pulmonary Disease (COPD) Patients
We hypothesize that ongoing and more severe airway inflammation in COPD may result from the impairment in activation of innate immune response
- Trial name
- NCT00826163
- Testing
- Budesonide
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Mahidol University
Endometriosis
Effect of Pre-operative Depo Medroxyprogesterone Acetate on Serum Anti-mullerian Hormone Level After Laparoscopic Ovarian Cystectomy of Endometriomas
The purpose of this study is to evaluate the ovarian reserve changes after preoperative depot medroxyprogesterone acetate (DMPA) in women with ovarian endometrioma undergoing laparoscopic cystectomy.
- Trial name
- NCT01791413
- Testing
- depot medroxyprogesterone acetate
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Primary Dysmenorrhea
The Efficacy of Ayurved Siriraj Prasaplai for Treatment Primary Dysmenorrhea
Ayurved Siriraj Prasaplai is a Thai traditional herbal drug for pain treatment. Mostly it was used for antipain during menstruation or dysmenorrhea.
- Trial name
- NCT01598012
- Testing
- Ayurved Siriraj Prasaplai with or without mefenamic acid
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Lung Surgery, Hypoxia
The Effect of Nasal Cannula During the First 2 Hours Postoperative in Patient Undergoing Thoracotomy
During early postoperative after lung resection surgery, patients without oxygen supplementation may experience hypoxemia. Oxygen supplementation can be given via oxygen mask or cannular.
- Conditions
- Lung Surgery, Hypoxia, Postoperative
- Trial name
- NCT01725464
- Testing
- oxygen cannular
- Where
- Thailand
- Volunteers
- 34 people
- Sponsor
- Mahidol University