Clinical trials: sponsored by Mahidol University
Adult Brain Tumor, Headache
Prevalence of Post-craniotomy Headache in Siriraj Hospital
Headache after major craniotomy may be a problem in taking care of the patients. The investigators want to identify the incidence of headache after major craniotomy and also the risk factors.
- Trial name
- NCT01806155
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Mahidol University
Nausea and Vomiting, Postoperative
10% Carbohydrate Drink for Preventing Post-operative Nausea and Vomiting (PONV) After Spinal Morphine
PONV after intrathecal morphine, occurs up to 30-40 percent. The patients having TKR normally are female, obese and non-smoker which are risk factors for PONV.
- Trial name
- NCT01301404
- Testing
- 10% carbohydrate drink
- Where
- Thailand
- Volunteers
- 120 people
- Sponsor
- Mahidol University
Peer Review, Research
Effect of Maternal and Neonatal Oxygenation
Intraoperative supplemental oxygen has been given for most parturients undergoing cesarean section under spinal anesthesia. However, evidences supporting the practice is not clear nowadays, especially for healthy parturients who…
- Trial name
- NCT01530971
- Testing
- Supplemental 3LPM oxygen via canula
- Where
- Thailand
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Chronic Idiopathic Thrombocytopenic Purpura, Helicobacter Pylori Infection
Helicobacter Pylori Infection in Children With Chronic Idiopathic Thrombocytopenic Purpura
Previous studies suggest that chronic idiopathic thrombocytopenic purpura is associated with Helicobacter pylori infection. The objective is to study the effect of Helicobacter pylori eradication on platelet count.
- Trial name
- NCT00467571
- Testing
- lansoprazole, clarithromycin, amoxycillin
- Where
- Thailand
- Volunteers
- 26 people
- Sponsor
- Mahidol University
Cataracts
Accuracy of Holladay 2 Formula in the Absence of Lens Thickness
Hypothesis: Holladay 2 formula is still accurate even used without lens thickness data.
- Trial name
- NCT01846078
- Testing
- optical biometric measurement (IOLMaster)
- Where
- Thailand
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Painful Diabetic Neuropathy
Capsaicin Nanoparticle in Patient With Painful Diabetic Neuropathy
The objectives of this study are to determine efficacy and safety of 0.75% topical capsaicin nanoparticle preparation versus placebo in patient with painful diabetic neuropathy.
- Trial name
- NCT01125215
- Testing
- 0.75% capsaicin nanoparticle cream
- Where
- 2 sites in Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Thalassemia
The Change of Coagulation Markers in Children With β-thalassemia Disease After Stem Cell Transplantation
Hypercoagulable state is well recognized in patients with β-thalassemia. Evidences of hypercoagulability include abnormal expression of phosphatidylserine on red blood cell (rbc) surface and consequent increased platelet…
- Trial name
- NCT00789516
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Wheat Allergy
Accuracy Of Skin Prick Test Using In-house Wheat Extract For The Diagnosis Of IgE-mediated Wheat Allergy: A Pilot Study
Nowadays, commercial wheat extract is widely accessible, and is used for skin prick test for wheat allergy. However, commercial wheat extracted for skin prick test have less precise test result compared to extract from omega-5…
- Trial name
- NCT01070368
- Testing
- Commercial extract and in-house wheat extract
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Mahidol University
Osteoarthritis of Knee
Accuracy of MRI-based Patients Matched Instruments vs Jig-based Instruments in Total Knee Arthroplasty (TKA)
Total knee arthroplasty (TKA) is the common and effective procedure for treatment of end-staged knee osteoarthritis. Postoperative alignment of TKA is one of the important factors which effects on survival of prosthesis.
- Trial name
- NCT01449474
- Testing
- Patient matched instruments, Jig based instruments
- Volunteers
- 80 people
- Sponsor
- Mahidol University
Allergic Rhinitis (Disorder)
The Development of Allergic Rhinitis in Children Previously Diagnosed as Nonallergic Rhinitis
The purpose of this study is to evaluate development of allergic rhinitis in children with nonallergic rhinitis.
- Trial name
- NCT01068808
- Testing
- skin prick test
- Where
- Thailand
- Volunteers
- 175 people
- Sponsor
- Mahidol University
Magnesium Sulphate, Post Pulmonary Resection
Magnesium Infusion for Pain Relief After Thoracotomy. A Randomized Controlled Trial.
All patients were premedicated with oral midazolam 5-15 mg. one hour before surgery. General anesthesia with double lumen endobronchial tube was given. Patient was induced by propofol and fentanyl.
- Conditions
- Magnesium Sulphate, Post Pulmonary Resection, Pain
- Trial name
- NCT01261702
- Testing
- magnesium sulphate
- Where
- Thailand
- Volunteers
- 32 people
- Sponsor
- Mahidol University
Osteoarthritis
Efficacy and Safety of Topical Essential Oil Extracted From Zingiber Cassumunar Rokb in Osteoarthritis
The objectives of this study are to assess short term efficacy and safety of of topical preparation of essential oil extracted from ZINGIBER CASSUMUNAR ROXB in patients suffering from osteoarthritic pain
- Trial name
- NCT01794260
- Testing
- Cream from Zingiber cassumunar Roxb. extract
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Mahidol University
Cognitive Function, Growth
Long-term Effects of Iron and Zinc Supplementation During Infancy on Cognitive Performance and Growth
The hypotheses of this study are: 1. Compared to children who received a placebo, children who received iron or zinc or iron and zinc combined will perform better on cognitive tests and will have better growth status at ages 8 to…
- Trial name
- FeZn_FU (NCT00824304)
- Where
- Thailand
- Volunteers
- 562 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Acute Uncomplicated Malaria With P.Vivax Infection
Comparison of Two Antimalarial Drugs Regimens in Patient With Plasmodium Vivax Malaria in Thailand
In Thailand, the proportion of P.vivax infection has now been increasing and is equal to Plasmodium falciparum since 1998. The incidence of P.vivax has recently been reported as 20 per 1000 population per year.
- Trial name
- NCT01662700
- Testing
- Artesunate, Chloroquine
- Where
- 4 sites in Thailand
- Volunteers
- 120 people
- Sponsor
- Mahidol University
Invasive Breast Cancer
Benefits of Breast MRI for Predicting of Histopathologic Cell Type of Small Breast Cancer
This study examines the additional benefits of magnetic resonance imaging (MRI) with Gadovist in early breast cancer with poor prognostic features.
- Trial name
- NCT01597999
- Testing
- MRI
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Pain, Craniotomy
Pain Prevalence After Major Craniotomy
Craniotomies are generally thought to be less painful than other operations. Indeed recent studies have confirmed that pain is a common problem during the postoperative phase following craniotomy.Pain not only causes discomfort…
- Trial name
- NCT01502540
- Where
- Thailand
- Volunteers
- 302 people
- Sponsor
- Mahidol University
Talipes Calcaneovalgus
Effectiveness of Parents' Manipulation in Newborn With Talipes Calcaneus
The purpose of this study is to determine effectiveness of parents' manipulation in newborn with talipes calcaneovalgus over observation group.
- Trial name
- NCT01767662
- Testing
- manipulation, No intervention
- Where
- Thailand
- Volunteers
- 160 people
- Sponsor
- Mahidol University
Abnormal Uterine Bleeding Unrelated to Menstrual Cycle
Cervical Ripening Before Endometrial Biopsy in Abnormal Uterine Bleeding Using Sublingual Misoprostol
Abnormal uterine bleeding is common in Thai women. Fractional curettage is an diagnostic procedure of this condition. Traditionally, fractional curettage is performed under local anesthesia such as paracervical nerve block or…
- Trial name
- NCT01762319
- Testing
- Misoprostol, Vitamin B6
- Where
- Thailand
- Volunteers
- 52 people
- Sponsor
- Mahidol University
Abnormal Uterine Bleeding Unrelated to Menstrual Cycle
Efficacy of Diclofenac on Pain During Endometrial Sampling
Abnormal uterine bleeding is common in Thai women. Traditionally, because of a larger number of patients, the diagnosis of its cause is performed via fractional curettage under local anesthesia such as paracervical nerve block or…
- Trial name
- NCT01762306
- Testing
- Diclofenac Potassium, Folic Acid
- Where
- Thailand
- Volunteers
- 90 people
- Sponsor
- Mahidol University
PIH
The Use of Sunscreen Starting on the First Day After Ablative Fractional Skin Resurfacing
The use of sunscreen on the first day after fractional ablative skin resurfacing may reduce the risk of post-inflammatory hyperpigmentation
- Trial name
- NCT01756664
- Testing
- Sunscreen, Vaseline
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mahidol University