Clinical trials: sponsored by Mahidol University
Drug Safety
Efficacy of Ascorbic Acid for Prevention of Colistin-Associated Nephrotoxicity
Ascorbic acid (Vitamin C) could protect renal toxicity from colistin.
- Trial name
- NCT01501968
- Testing
- Colistin, Colistin + Ascorbic acid
- Where
- Thailand
- Volunteers
- 54 people
- Sponsor
- Mahidol University
Drug Safety
Colistin Versus Colistin Plus Fosfomycin for Infections Caused by MDR Acinetobacter Baumannii
In Siriraj Hospital, colistin alone for treatment of MDR A. baumannii contributed to mortality 45% Fosfomycin is an antimicrobial which has activity against gram-negative bacterial including MDR A.
- Trial name
- NCT01297894
- Testing
- colistin, colistin plus fosfomycin
- Where
- Thailand
- Volunteers
- 92 people
- Sponsor
- Mahidol University
Hot Flashes
Black Cohosh Extract for the Management of Moderate to Severe Menopausal Symptoms in Thai Women
Cimicifuga racemosa (black cohosh) rhizome and root extract have been used to treat menopausal symptoms. To date, there are still scarce information about its efficacy in Thai women with menopausal symptoms.
- Trial name
- NCT01487694
- Testing
- cimicifuga racemosa
- Where
- Thailand
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Anesthesia, Time
Can the Usage of Regional Block Room Save the Time of Anesthesia Team
Study of time usage of anesthesia team inside the main operating room compares between 2 groups of Performing regional anesthesia inside the operating room Performing regional anesthesia in the block room Study purpose: How much…
- Trial name
- NCT01499589
- Testing
- regional anesthesia
- Where
- Thailand
- Volunteers
- 800 people
- Sponsor
- Mahidol University
Stevens-Johnson Syndrome
Efficacy of 0.05% Cyclosporin Eye Drop in Stevens Johnson Syndrome Patient With Chronic Dry Eye
The purpose of this study is to evaluate the efficacy of 0.05% cyclosporin ophthalmic emulsion (Restasis) in patients with Stevens-Johnson syndrome that have dry eyes by subjective symptoms and signs.
- Trial name
- NCT01488396
- Testing
- 0.05%cyclosporin eye drop
- Where
- Thailand
- Volunteers
- 31 people
- Sponsor
- Mahidol University
Severe Ocular Surface Damage, Limbal Deficiency
Efficacy of Cultivated Corneal Epithelial Stem Cell for Ocular Surface Reconstruction
The purpose of this study is to elucidate the appropriate condition of developing cultivated corneal epithelial graft and evaluate the surgical outcome of transplantation of the cultivated corneal epithelial stem cell in the…
- Trial name
- NCT01237600
- Testing
- Cultivated limbal transplantation
- Where
- Thailand
- Volunteers
- 19 people
- Sponsor
- Mahidol University
OSA, Complication
Efficacy of Adjustable Thermoplastic Oral Appliances in Patient With OSA
Somnoguard, a titratable-thermoplastic oral appliances for the treatment of OSA, has been reported its safety and efficacy in Caucasians at least in the short-term. However, there has been no reports in Thai patients.
- Trial name
- ThaiSomnoguard (NCT01466309)
- Testing
- Somnoguard oral appliances
- Where
- Thailand
- Volunteers
- 50 people
- Sponsor
- Mahidol University
Osteoarthritis of Knee
Temporary Clamping of Drains Combined With Tranexamic Acid Reduce Blood Loss After TKA: A Prospective RCT
Total knee arthroplasty (TKA) may be associated with significant blood loss, and transfusion carries substantial risk of immunologic reaction and disease transmission.
- Trial name
- NCT01449552
- Testing
- Tranexamic acid, Drain clamping, Drain clamping and tranexamic acid
- Volunteers
- 240 people
- Sponsor
- Mahidol University
Stroke
Creative Therapy to Affect Stroke Outcomes
Stroke is one of the common diseases in the elderly. It is the third ranking cause of death and affects health care system in our country.
- Trial name
- NCT01455155
- Testing
- Creative therapy (art and music therapy), Physical therapy
- Where
- Thailand
- Volunteers
- 204 people
- Sponsor
- Mahidol University
Respiratory Paralysis
Diaphragmatic Height Index: the New Diagnostic Test for Phrenic Nerve Dysfunction
Diaphragmatic contraction is controlled by phrenic nerve which consists of anterior rami of 3rd- 5th cervical nerve roots. Usually, It can't be evaluated from history taking and physical examination.
- Trial name
- NCT01450917
- Volunteers
- 245 people
- Sponsor
- Mahidol University
Osteoarthritis of Knee
The Recovery Time of Quadriceps Strength After Total Knee Arthroplasty (TKA): The Effect of Quadriceps Incision Length
Minimally invasive total knee arthroplasty (MIS-TKA) became the popular technique. It had the less postoperative pain and shorter recovery time compared to the conventional technique.
- Trial name
- NCT01450904
- Testing
- Quadriceps incision < 2 cm, Quadriceps incision 2-4 cm, Quadriceps incision > 4 cm
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Pain, Vaginal Hysterectomy
0.05 Versus 0.1 mg Spinal Morphine for Reducing Morphine Requirement After Vaginal Hysterectomy
This study aims to compare the efficacy of 0.05 mg and 0.1 mg spinal morphine in reducing postoperative morphine requirement in patients undergoing vaginal hysterectomy with/without anterior and posterior vaginoplasty.
- Trial name
- NCT01079754
- Testing
- Spinal morphine 0.05 mg, Spinal morphine 0.1 mg
- Where
- Thailand
- Volunteers
- 72 people
- Sponsor
- Mahidol University
Pain
0.05 mg Versus 0.1 mg Spinal Morphine for Reducing Morphine Requirement After Vaginal Hysterectomy
This study aims to compare the effect of spinal morphine between the dose 0.05 mg and 0.1 mg on the amount of morphine during the first 24 hours postoperative.
- Trial name
- NCT01080911
- Testing
- Morphine
- Where
- Thailand
- Volunteers
- 72 people
- Sponsor
- Mahidol University
Carcinoma, Hepatocellular
Efficacy and Safety of Sorafenib (Nexavar) in Combination With Gemcitabine in Advanced Hepatocellular Carcinoma (HCC)
This study is to evaluate the efficacy and safety of Sorafenib in combination with Gemcitabine in patients with advanced/unresectable HCC.
- Trial name
- NCT00703365
- Testing
- Sorafenib and Gemcitabine
- Where
- 3 sites in Thailand
- Volunteers
- 45 people
- Sponsor
- Mahidol University
Renal Cell Carcinoma
Efficacy and Safety of Sorafenib in Advanced Renal Cell Carcinoma (RCC)
This is the early access programme (EAP) of sorafenib in the indication of advanced renal cell carcinoma (RCC). The study is to evaluate the efficacy and safety of sorafenib in patients with advanced RCC.
- Trial name
- NCT00478114
- Testing
- sorafenib
- Where
- Thailand
- Volunteers
- 15 people
- Sponsor
- Mahidol University
Femoral Neck Fractures
Intrathecal Morphine,Femoral Nerve Block,Periarticular Bupivacaine Infiltration for Pain After Intramedullary Hip Screw
Falls are a common problem in elderly patients resulting fractured femur, which require early operation. Adequate postoperative pain control will provide good recovery.
- Trial name
- NCT01219088
- Testing
- Bupivacaine, morphine
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Mahidol University
Morphine Adverse Reaction
Efficacy of Intramuscular Naloxone 0.4mg. in Prophylaxis of Intrathecal Morphine Induced Pruritus After Cesarean Section
The purpose of this study is to determine whether intramuscular naloxone 0.4mg. is effective in prophylaxis of intrathecal morphine induced pruritus after cesarean section.
- Trial name
- NCT00890942
- Testing
- naloxone, normal saline
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Gingivitis, Halitosis
Effect of Mouthwash Containing Camellia Sinensis Extracts on Oral Malodor
The purpose of this study is to determine effect of Mouthwash containing Camellia sinensis extracts on oral malodor and gingival inflammation in gingivitis subjects.
- Trial name
- NCT00932347
- Testing
- Camellia sinensis mouthwash
- Where
- 2 sites in Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Postoperative Pain
Quality of Postoperative Pain Management in Cardiac Surgical Patients
The purpose of this study is to determine the incidence and risk factors of moderate to severe pain after cardiac surgery, and compare the preoperative pain expectation and postoperative pain experience in the same patient.
- Trial name
- NCT00949429
- Where
- Thailand
- Volunteers
- 300 people
- Sponsor
- Mahidol University
Wrinkles
Argireline in Treatment of Periorbital Wrinkles
The purpose of this study is to determine whether La Jolie gel is effective in the treatment of periorbital wrinkles.
- Trial name
- NCT01381484
- Testing
- 10% Argireline
- Where
- Thailand
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mahidol University